Novel role of curcumin combined with bone marrow transplantation in reversing experimental diabetes: Effects on pancreatic islet regeneration, oxidative stress, and inflammatory cytokines

European Journal of Pharmacology

Volumn 658, Issue 1, 2011, Pages 41-48

  El Azab, Mona F ^a   Attia, Fadia M ^b   El Mowafy, Abdalla M ^c  

^a Suez Canal University   (Egypt)

^b Suez Canal University Faculty of Medicine   (Egypt)

^c MANSOURA UNIVERSITY   (Egypt)

Author keywords

Antioxidant; Bone marrow transplantation; Curcumin; Diabetes; Inflammation; Islet regeneration

Indexed keywords

CURCUMIN; GLUCOSE; INSULIN; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BONE MARROW TRANSPLANTATION; CELL REGENERATION; CONTROLLED STUDY; DIABETES MELLITUS; DRUG EFFECT; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; HYPOINSULINEMIA; INSULIN BLOOD LEVEL; INSULIN RELEASE; LIPID PEROXIDATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; WEIGHT GAIN;

ANIMALS; ANTIOXIDANTS; BLOOD GLUCOSE; BODY WEIGHT; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; CURCUMIN; CYTOKINES; DIABETES MELLITUS, EXPERIMENTAL; GLUCOSE TOLERANCE TEST; INFLAMMATION; INSULIN; INSULIN-SECRETING CELLS; INTERLEUKIN-1BETA; ISLETS OF LANGERHANS; LIPID PEROXIDATION; MICE; OXIDATIVE STRESS; REGENERATION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 79952817657     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.02.010     Document Type: Article

References (54)

1. H. Aebi Catalase in vitro Meth. Enzymol. 105 1984 121 126
2. J.F. Alvarez, A. Barbera, B. Nadal, S. Barcelo-Batllori, S. Piquer, M. Claret, J.J. Guinovart, N. Guinovart, and R. Gomis Stable and functional regeneration of pancreatic beta-cell population in nSTZ-rats treated with tungstate Diabetologia 47 2004 470 477 (Pubitemid 38491243)
3. P. Anand, A.B. Kunnumakkara, R.A. Newman, and B.B. Aggarwal Bioavailability of curcumin: problems and promises Mol. Pharmacol. 4 2007 807 818
4. P.S. Babu, and K. Srinivasan Influence of dietary curcumin and cholesterol on the progression of experimentally induced diabetes in albino rat Mol. Cell. Biochem. 152 1995 13 21
5. J.F. Bach Insulin-dependent diabetes mellitus as an autoimmune disease Endocr. Rev. 15 1994 516 542
6. M. Banerjee, and R.R. Bhonde Islet generation from intra islet precursor cells of diabetic pancreas: in vitro studies depicting in vivo differentiation JOP 4 2003 137 145 (Pubitemid 38963781)
7. M. Banerjee, A. Kumar, and R. Bhonde Reversal of experimental diabetes by multiple bone marrow transplantation Biochem. Biophys. Res. Commun. 328 2005 318 325 (Pubitemid 40164671)
8. A. Colman Making new beta cells from stem cells Semin. Cell Dev. Biol. 15 2004 337 345 (Pubitemid 38582002)
9. D. Donnini, A.M. Zambito, and G. Perella Glucose may induce cell death through a free radical-mediated mechanism Biochem. Biophys. Res. Commun. 219 1996 412 417 (Pubitemid 26090285)
10. M.F. El-Azab, H.Z. Hishe, Y.M. Moustafa, and E.E. El-Awady Effect of resveratrol and curcumin on tumor volume and survival in Ehrlich ascites carcinoma-bearing mice Bull. Fac. Pharm. Cairo Univ. 47 2009 207 223
11. M. El-Azab, H. Hishe, Y. Moustafa, and E. El-Awady Anti-angiogenic effect of resveratrol or curcumin in Ehrlich ascites carcinoma-bearing mice Eur. J. Pharmacol. 652 2011 4 17
12. A.M. El-Mowafy, M.E. El-Mesery, H.A. Salem, M.M. Al-Gayyar, and M.M. Darweish Prominent chemopreventive and chemoenhancing effects for resveratrol: unraveling molecular targets and the role of CRP Chemotherapy 56 2010 60 65
13. C. Feillet-Coudray, E. Rock, C. Coudray, K. Grzelkowska, V. Azais-Braesco, D. Dardevet, and A. Mazur Lipid peroxidation and antioxidant status in experimental diabetes Clin. Chim. Acta 284 1999 31 43 (Pubitemid 29324863)
14. A. Fernandes, L.C. King, Y. Guz, R. Stein, C.V. Wright, and G. Teitelman Differentiation of new insulin-producing cells is induced by injury in adult pancreatic islets Endocrinology 138 1997 1750 1762 (Pubitemid 27137131)
15. S. Fujisawa, T. Atsumi, M. Ishihara, and Y. Kadoma Cytotoxicity, reactive oxygen species - generating activity and radical scavenging activity of curcumin and other related compounds Anticancer Res. 24 2004 563 570
16. S.C. Gautam, X. Gao, and S. Dulchavsky Immunomodulation by curcumin Adv. Exp. Med. Biol. 595 2007 321 341
17. A. Grandjean-Laquerriere, S.C. Gangloff, R. Le Naour, C. Trentesaux, W. Hornebeck, and M. Guenounou Relative contribution of NFkB and AP-1 in the modulation by curcumin and pyrrolidine dithiocarbamate of the UVB-induced cytokine expression by kertinocytes Cytokine 18 2002 168 177 (Pubitemid 34775439)
18. A. Gururaj, M. Belakavadi, D. Venkatesh, D. Marmé, and B. Salimath Molecular mechanisms of anti-angiogenic effect of curcumin Biochem. Biophys. Res. Commun. 297 2002 934 942 (Pubitemid 35230341)
19. H.E. Hussain Hypoglycemic, hypolipidemic and antioxidant properties of combination of curcumin from Curcuma longa, Linn. and partially purified product from Abroma augusta, Linn. in streptozotocin induced diabetes Ind. J. Clin. Biochem. 17 2002 33 43
20. A. Ianus, G.G. Holz, N.D. Theise, and M.A. Hussain In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion J. Clin. Invest. 111 2003 843 850 (Pubitemid 37074959)
21. L. Jin, H.Y. Xue, L.J. Jin, S.Y. Li, and Y.P. Xu Antioxidant and pancreas-protective effect of aucubin on rats with streptozotocin-induced diabetes Eur. J. Pharmacol. 582 2008 162 167
22. M. Kanitkar, K. Gokhale, S. Galande, and R.R. Bhonde Novel role of curcumin in the prevention of cytokine-induced islet death in vitro and diabetogenesis in vivo Br. J. Pharmacol. 155 2008 702 713
23. S.H. Kim, S.H. Hyun, and S.Y. Choung Anti-diabetic effect of cinnamon extract on blood glucose in db/db mice J. Ethnopharmacol. 104 2006 119 123 (Pubitemid 43234091)
24. S. Kim, J.S. Shin, H.J. Kim, R.C. Fisher, M.J. Lee, and C.W. Kim Streptozotocin-induced diabetes can be reversed by hepatic oval cell activation through hepatic transdifferentiation and pancreatic islet regeneration Lab. Invest. 87 2007 702 712 (Pubitemid 46920105)
25. R.A. Lawrence, and R.F. Burk Glutathione peroxidase activity in selenium deficient rat liver Biochem. Biophys. Res. Commun. 71 1976 952 958
26. A. Lechner, and J.F. Habener Stem/progenitor cells derived from adult tissues: potential for the treatment of diabetes mellitus Am. J. Physiol. Endocrinol. Metab. 284 2003 259 266
27. Y.C. Lei, J.S. Hwang, C.C. Chan, C.T. Lee, and T.J. Cheng Enhanced oxidative stress and endothelial dysfunction in streptozotocin-diabetic rats exposed to fine particles Environ. Res. 99 2005 335 343
28. T. Mandrup-Poulsen, K. Bendtzen, J.H. Nielsen, G. Bendixen, and J. Nerup Cytokines cause functional and structural damage to isolated islets of Langerhans Allergy 40 1985 424 429 (Pubitemid 16256630)
29. D. Mathis, L. Vence, and C. Benoist Beta-cell death during progression to diabetes Nature 414 2001 792 798
30. D.O. Moon, M.O. Kim, Y.H. Choi, Y.M. Park, and G.Y. Kim Curcumin attenuates inflammatory response in IL-1beta-induced human synovial fibroblasts and collagen-induced arthritis in mouse model Int. Immunopharmacol. 10 2010 605 610
31. R. Motterlini, R. Foresti, R. Bassi, and C.J. Green Curcumin, an antioxidant and anti-inflammatory agent, induces heme oxygenase-1 and protects endothelial cells against oxidative stress Free Radic. Biol. Med. 28 2000 1303 1312 (Pubitemid 30417475)
32. M. Nishikimi, N. Appaji, and K. Yagi The occurrence of superoxide anion in the reaction of reduced phenazine methosulfate and molecular oxygen Biochem. Biophys. Res. Commun. 46 1972 849 854
33. H. Ohkawa, N. Ohishi, and K. Yagi Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction Anal. Biochem. 95 1979 351 358 (Pubitemid 9194347)
34. T. Ohkuwa, Y. Sato, and M. Naoi Hydroxyl radical formation in diabetic rat induced by streptozotocin Life Sci. 56 1995 1789 1798
35. L. Pari, and P. Murugan Effect of thetrahydrocurcumin on blood glucose, plasma insulin and hepatic key enzymes in streptozotocin induced diabetic rats Basic Clin. Physiol. Pharmacol. 16 2005 257 274 (Pubitemid 43089170)
36. T.T. Phan, P. See, S.T. Lee, and S.Y. Chan Protective effects of curcumin against oxidative damage on skin cells in vitro: its implications for wound healing J. Trauma 51 2001 927 931 (Pubitemid 33117458)
37. A. Rabinovitch, and W.L. Suarez-Pinzon Cytokines and their roles in pancreatic islet beta-cell destruction and insulin-dependent diabetes mellitus Biochem. Pharmacol. 55 1998 1139 1149 (Pubitemid 28206701)
38. D.A. Rees, and J.C. Alcolado Animal models of diabetes mellitus Diabet. Med. 22 2005 359 370 (Pubitemid 40516231)
39. M.V. Risbud, and R.R. Bhonde Models of pancreatic regeneration in diabetes Diab. Res. Clin. Pract. 58 2002 155 165 (Pubitemid 36159011)
40. L. Rosenberg In vivo cell transformation: neogenesis of beta cells from pancreatic ductal cells Cell Transplant. 4 1995 371 383
41. A.K. Saxena, P. Srivastava, R.K. Kale, and N.Z. Baquer Impaired antioxidant status in diabetic rat liver. Effect of vanadate Biochem. Pharmacol. 45 1993 539 542 (Pubitemid 23064556)
42. S. Sharma, K. Chopra, S.K. Kulkarni, and J.N. Agrewala Resveratrol and curcumin suppress immune response through CD28/CTLA-4 and CD80 co-stimulatory pathway Clin. Exp. Immunol. 147 2007 155 163 (Pubitemid 44915567)
43. S.A. Shirley, A.J. Montpetit, R.F. Lockey, and S.S. Mohapatra Curcumin prevents human dendritic cell response to immune stimulants Biochem. Biophys. Res. Commun. 374 2008 431 436
44. J.M.W. Slack Developmental biology of the pancreas Development 121 1995 1569 1580
45. A. Srinivasan, V.P. Menon, V. Periaswamy, and K.N. Rajasekaran Protection of pancreatic beta cell by the potential anti-oxidant bis-o-hydroxycinnmoyl methane, analogue of natural curcuminoid in experimental diabetes J. Pharm. Sci. 6 2003 327 333 (Pubitemid 38097546)
46. S.A. Steer, A.L. Scarim, K.T. Chambers, and J.A. Corbett Interleukin-1 stimulates beta-cell necrosis and release of the immunological adjuvant HMGB1 PLoS Med. 3 2006 253 265
47. S. Stosić-Grujicić, D. Maksimović, V. Badovinac, T. Samardzić, V. Trajković, M. Lukić, and M. Mostarica Stojković Antidiabetogenic effect of pentoxifylline is associated with systemic and target tissue modulation of cytokines and nitric oxide production J. Autoimmun. 16 2001 47 58 (Pubitemid 32174174)
48. T. Szkudelski The mechanism of alloxan and streptozotocin action in B cells of rat pancreas Physiol. Res. 50 2001 536 546
49. M. Tiedge, S. Lortz, J. Drinkgern, and S. Lenzen Relation between antioxidant enzyme gene expression and antioxidative defense status of insulin-producing cells Diabetes 46 1997 1733 1742 (Pubitemid 27456404)
50. N.H. Ugochukwu, N.D. Bagayoko, and M.E. Antwi The effects of dietary caloric restriction on antioxidant status and lipid peroxidation in mild and severe streptozotocin-induced diabetic rats Clin. Chim. Acta 348 2004 121 129 (Pubitemid 39209010)
51. S. Venkateswaran, and L. Pari Antioxidant effect of Phaseolus vulgaris in streptozotocin-induced diabetic rats Asia Pac. J. Clin. Nutr. 11 2002 206 209
52. W.M. Weber, L.A. Hunsaker, C.N. Roybal, E.V. Borovnikova-Marjon, S.F. Abcouwer, R.E. Royer, L.M. Deck, and D.L. Vander Jagt Activation of NF kappa B is inhibited by curcumin and related enones Bioorg. Med. Chem. 14 2006 2450 2461 (Pubitemid 43254754)
53. S.P. Weisberg, R. Leibel, and D.V. Tortoriello Dietary curcumin significantly improves obesity-associated inflammation and diabetes in mouse models of diabesity Endocrinology 149 2008 3549 3558 (Pubitemid 351919581)
54. C. Zhang, A. Browne, D. Child, and R.E. Tanzi Curcumin decreases amyloid-beta peptide levels by attenuating the maturation of amyloid-beta precursor protein J. Biol. Chem. 285 2010 28472 28480