Novel role of curcumin in the prevention of cytokine-induced islet death in vitro and diabetogenesis in vivo

British Journal of Pharmacology

Volumn 155, Issue 5, 2008, Pages 702-713

  Kanitkar, M ^a   Gokhale, K ^a   Galande, S ^a   Bhonde, R R ^a  

^a NATIONAL CENTRE FOR CELL SCIENCE   (India)

Author keywords

Curcumin; Cytokines; Islet death; MLD STZ

Indexed keywords

CURCUMIN; CYTOKINE; GLUCOSE TRANSPORTER 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL DEATH; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; DIABETOGENESIS; DISEASE COURSE; DRUG EFFICACY; DRUG MECHANISM; GLUCOSE BLOOD LEVEL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET CELL; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN PHOSPHORYLATION; STREPTOZOCIN DIABETES;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BLOOD GLUCOSE; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; CURCUMIN; CYTOKINES; DIABETES MELLITUS, EXPERIMENTAL; I-KAPPA B PROTEINS; INSULIN; ISLETS OF LANGERHANS; MALE; MICE; MICE, INBRED STRAINS; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 54949151846     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/bjp.2008.311     Document Type: Article

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