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Volumn 14, Issue 2, 2011, Pages 204-211

Isoflavones: Effects on bone health

Author keywords

bone turnover; genistein; Isoflavones; osteoporosis

Indexed keywords

BIOCHEMICAL MARKER; GENISTEIN; ISOFLAVONE; PLACEBO; SOYBEAN PROTEIN; TAMOXIFEN;

EID: 79952807333     PISSN: 13697137     EISSN: 14730804     Source Type: Journal    
DOI: 10.3109/13697137.2010.529198     Document Type: Review
Times cited : (34)

References (50)
  • 1
    • 27744483584 scopus 로고    scopus 로고
    • Available medical choices for the management of menopause
    • DOI 10.1016/j.maturitas.2005.09.008, PII S0378512205002550, Management of the Ssymptomatic Postmenopusal Women
    • Castelo-Branco C, Palacios S, Calaf J, Vázquez F, Lanchares JL. Available medical choices for the management of menopause. Maturitas 2005;52(Suppl 1):S61-70 (Pubitemid 41625567)
    • (2005) Maturitas , vol.52 , Issue.SUPPL. 1
    • Castelo-Branco, C.1    Palacios, S.2    Calaf, J.3    Vazquez, F.4    Lanchares, J.L.5
  • 2
    • 77953745547 scopus 로고    scopus 로고
    • A brief historical overview of the past two decades of soy and isoflavone research
    • Messina M. A brief historical overview of the past two decades of soy and isoflavone research. J Nutr 2010;140:1350-4S
    • (2010) J Nutr , vol.140
    • Messina, M.1
  • 3
    • 77952270920 scopus 로고    scopus 로고
    • Cardiovascular friendly natural products: A promising approach in the management of CVD
    • Shukla SK, Gupta S, Ojha SK, Sharma SB. Cardiovascular friendly natural products: A promising approach in the management of CVD. Nat Prod Res 2010;24:873-98
    • (2010) Nat Prod Res , vol.24 , pp. 873-898
    • Shukla, S.K.1    Gupta, S.2    Ojha, S.K.3    Sharma, S.B.4
  • 4
    • 67650242711 scopus 로고    scopus 로고
    • Soybean isoflavones in bone health
    • Ishimi Y. Soybean isoflavones in bone health. Forum Nutr 2009; 61:104-16
    • (2009) Forum Nutr , vol.61 , pp. 104-116
    • Ishimi, Y.1
  • 5
    • 0031039888 scopus 로고    scopus 로고
    • Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors and α and β
    • DOI 10.1210/en.138.3.863
    • Kuiper GG, Carlsson B, Grandien K, et al. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta. Endocrinology 1997;138: 863-70 (Pubitemid 27089735)
    • (1997) Endocrinology , vol.138 , Issue.3 , pp. 863-870
    • Kuiper, G.G.J.M.1    Carlsson, B.2    Grandien, K.3    Enmark, E.4    Haggblad, J.5    Nilsson, S.6    Gustafsson, J.-A.7
  • 7
    • 0029945381 scopus 로고    scopus 로고
    • Variable effects of tyrosine kinase inhibitors on avian osteoclastic activity and reduction of bone loss in ovariectomized rats
    • DOI 10.1002/(SICI)1097-4644(19960616)61:4<629::AID-JCB17>3.0.CO;2-A
    • Blair HC, Jordan SE, Peterson TG, Barnes S. Variable effects of tyrosine kinase inhibitors on avian osteoclastic activity and reduction of bone loss in ovariectomized rats. J Cell Biochem 1996;61:629-37 (Pubitemid 26240141)
    • (1996) Journal of Cellular Biochemistry , vol.61 , Issue.4 , pp. 629-637
    • Blair, H.C.1    Jordan, S.E.2    Peterson, T.G.3    Barnes, S.4
  • 10
    • 0033966168 scopus 로고    scopus 로고
    • Stimulatory effect of daidzein in osteoblastic MC3T3-E1 cells
    • DOI 10.1016/S0006-2952(99)00351-2, PII S0006295299003512
    • Sugimoto E, Yamaguchi M. Stimulatory effect of daidzein in osteoblastic MC3T3-E1 cells. Biochem Pharmacol 2000;59: 471-5 (Pubitemid 30045585)
    • (2000) Biochemical Pharmacology , vol.59 , Issue.5 , pp. 471-475
    • Sugimoto, E.1    Yamaguchi, M.2
  • 12
    • 0028418866 scopus 로고
    • Evaluation of the effect of soybean milk and soybean milk peptides on bone metabolism in the rat model with ovariectomized osteoporosis
    • Omi N, Aoi S, Murata K, Ezawa I. Evaluation of the effect of soybean milk and soybean milk peptides on bone metabolism in the rat model with ovariectomized osteoporosis. J Nutr Sci Vitaminol (Tokyo) 1994;40:201-11
    • (1994) J Nutr Sci Vitaminol (Tokyo) , vol.40 , pp. 201-211
    • Omi, N.1    Aoi, S.2    Murata, K.3    Ezawa, I.4
  • 19
    • 62749123477 scopus 로고    scopus 로고
    • Neonatal exposure to daidzein, genistein, or the combination modulates bone development in female CD-1 mice
    • Kaludjerovic J, Ward WE. Neonatal exposure to daidzein, genistein, or the combination modulates bone development in female CD-1 mice. J Nutr 2009;139:467-73
    • (2009) J Nutr , vol.139 , pp. 467-473
    • Kaludjerovic, J.1    Ward, W.E.2
  • 20
    • 46849116642 scopus 로고    scopus 로고
    • Effects of genistein on vertebral trabecular bone microstructure, bone mineral density, microcracks, osteocyte density, and bone strength in ovariectomized rats
    • DOI 10.1007/s00774-007-0830-4
    • Dai R, Ma Y, Sheng Z, et al. Effects of genistein on vertebral trabecular bone microstructure, bone mineral density, microcracks, osteocyte density, and bone strength in ovariectomized rats. J Bone Miner Metab 2008;26:342-9 (Pubitemid 351953024)
    • (2008) Journal of Bone and Mineral Metabolism , vol.26 , Issue.4 , pp. 342-349
    • Dai, R.1    Ma, Y.2    Sheng, Z.3    Jin, Y.4    Zhang, Y.5    Fang, L.6    Fan, H.7    Liao, E.8
  • 23
    • 0031774496 scopus 로고    scopus 로고
    • Soy protein isolate diet does not prevent increased cortical bone turnover in ovariectomized macaques
    • DOI 10.1007/s002239900479
    • Lees CJ, Ginn TA. Soy protein isolate diet does not prevent increased cortical bone turnover in ovariectomized macaques. Calcif Tissue Int 1998;62:557-8 (Pubitemid 28240893)
    • (1998) Calcified Tissue International , vol.62 , Issue.6 , pp. 557-558
    • Lees, C.J.1    Ginn, T.A.2
  • 24
  • 25
    • 0035181619 scopus 로고    scopus 로고
    • High dietary phytoestrogen intake is associated with higher bone mineral density in postmenopausal but not premenopausal women
    • DOI 10.1210/jc.86.11.5217
    • Mei J, Yeung SSC, Kung AWC. High dietary phytoestrogen intake is associated with higher bone mineral density in postmenopausal but not premenopausal women. J Clin Endocrinol Metab 2001;86:5217-21 (Pubitemid 33070238)
    • (2001) Journal of Clinical Endocrinology and Metabolism , vol.86 , Issue.11 , pp. 5217-5221
    • Mei, J.1    Yeung, S.S.C.2    Kung, A.W.C.3
  • 26
    • 0035161868 scopus 로고    scopus 로고
    • Soy intake related to menopausal symptoms, serum lipids, and bone mineral density in postmenopausal Japanese women
    • DOI 10.1016/S0029-7844(00)01080-2, PII S0029784400010802
    • Somekawa Y, Chiguchi M, Ishibashi T, Aso T. Soy intake related to menopausal symptoms, serum lipids, and bone mineral density in postmenopausal Japanese women. Obstet Gynecol 2001;97: 109-15 (Pubitemid 32057167)
    • (2001) Obstetrics and Gynecology , vol.97 , Issue.1 , pp. 109-115
    • Somekawa, Y.1    Chiguchi, M.2    Ishibashi, T.3    Aso, T.4
  • 27
    • 0006847291 scopus 로고    scopus 로고
    • Relationship between urinary isoflavones and bone metabolism in postmenopausal Japanese women
    • Fukui Y, Miura A, Nara Y, Uesugi T, Yamori H, Yamori Y. Relationship between urinary isoflavones and bone metabolism in postmenopausal Japanese women. J Nutr 2000;130:686S
    • (2000) J Nutr , vol.130
    • Fukui, Y.1    Miura, A.2    Nara, Y.3    Uesugi, T.4    Yamori, H.5    Yamori, Y.6
  • 28
    • 0006770340 scopus 로고    scopus 로고
    • Soy consumption and bone mineral density in older Japanese American women in King County, Washington
    • Rice MM, LaCroix AZ, Lampe JW, et al. Soy consumption and bone mineral density in older Japanese American women in King County, Washington. J Nutr 2000;130:685S
    • (2000) J Nutr , vol.130
    • Rice, M.M.1    LaCroix, A.Z.2    Lampe, J.W.3
  • 29
    • 0034470114 scopus 로고    scopus 로고
    • Dietary phytoestrogen intake in mid-life Australian-born women
    • Guthrie JR, Ball M, Murkies A, Dennerstein L. Dietary phytoestrogen intake in mid-life Australian-born women. Climacteric 2000;3:254-61
    • (2000) Climacteric , vol.3 , pp. 254-261
    • Guthrie, J.R.1    Ball, M.2    Murkies, A.3    Dennerstein, L.4
  • 30
    • 0034855063 scopus 로고    scopus 로고
    • Dietary soy supplementation reduces LDL oxidation and bone turnover in healthy post-menopausal women
    • Scheiber M, Liu J, Subbiah M, Rebar R, Setchell KDR. Dietary soy supplementation reduces LDL oxidation and bone turnover in healthy post-menopausal women. Menopause 2001; 8:384-92
    • (2001) Menopause , vol.8 , pp. 384-392
    • Scheiber, M.1    Liu, J.2    Subbiah, M.3    Rebar, R.4    Setchell, K.D.R.5
  • 31
    • 10944269574 scopus 로고    scopus 로고
    • Soybean intake and bone mineral density change in Korean college women. Epidemiological observations
    • Song YS, Paik HY. Soybean intake and bone mineral density change in Korean college women. Epidemiological observations. J Nutr 2002;132:616S.
    • (2002) J Nutr , vol.132
    • Song, Y.S.1    Paik, H.Y.2
  • 32
    • 0033934021 scopus 로고    scopus 로고
    • Osteoporosi e fitoestrogeni: Valutazione della densita minerale ossea mediante tomografia computerizzata quantitativa periferica nelle donne lattoovovegetariane nella premenopausa
    • Di Leo C, Tarolo GL, Bestetti A, et al. Osteoporosis and phytoestrogens: An assessment of bone mineral density via quantitative peripheral computed tomography in milk-egg-vegetarian women in the premenopause. Radiol Med (Torino) 2000;99:250-7 (Pubitemid 30422501)
    • (2000) Radiologia Medica , vol.99 , Issue.4 , pp. 250-257
    • Di Leo, C.1    Tarolo, G.L.2    Bestetti, A.3    Tagliabue, L.4    Del Sole, A.5    Aliberti, G.6    Cestaro, B.7    Pepe, L.8
  • 33
    • 0036789026 scopus 로고    scopus 로고
    • Soy isoflavones: No effects on bone mineral content and bone mineral density in healthy, menstruating young adult women after one year
    • Anderson JJ, Chen X, Boass A, et al. Soy isoflavones: No effects on bone mineral content and bone mineral density in healthy, menstruating young adult women after one year. J Am Coll Nutr 2002;21:388-93
    • (2002) J Am Coll Nutr , vol.21 , pp. 388-393
    • Anderson, J.J.1    Chen, X.2    Boass, A.3
  • 34
    • 40549095352 scopus 로고    scopus 로고
    • Long-term consumption of isoflavone-enriched foods does not affect bone mineral density, bone metabolism, or hormonal status in early postmenopausal women: A randomized, double-blind, placebo controlled study
    • Brink E, Coxam V, Robins S, Wahala K, Cassidy A, Branca F; PHYTOS Investigators. Long-term consumption of isoflavoneenriched foods does not affect bone mineral density, bone metabolism, or hormonal status in early postmenopausal women: A randomized, double-blind, placebo controlled study. Am J Clin Nutr 2008;87:761-70 (Pubitemid 351364559)
    • (2008) American Journal of Clinical Nutrition , vol.87 , Issue.3 , pp. 761-770
    • Brink, E.1    Coxam, V.2    Robins, S.3    Wahala, K.4    Cassidy, A.5    Branca, F.6
  • 35
    • 67649887107 scopus 로고    scopus 로고
    • Soy proteins and isoflavones affect bone mineral density in older women: A randomized controlled trial
    • Kenny AM, Mangano KM, Abourizk RH, et al. Soy proteins and isoflavones affect bone mineral density in older women: A randomized controlled trial. Am J Clin Nutr 2009;90:234-42
    • (2009) Am J Clin Nutr , vol.90 , pp. 234-242
    • Kenny, A.M.1    Mangano, K.M.2    Abourizk, R.H.3
  • 38
    • 34948856861 scopus 로고    scopus 로고
    • Possible role of equol status in the effects of isoflavone on bone and fat mass in postmenopausal Japanese women: A double-blind, randomized, controlled trial
    • DOI 10.1097/gme.0b013e3180305299
    • Wu J, Oka J, Ezaki J, et al. Possible role of equol status in the effects of isoflavone on bone and fat mass in postmenopausal Japanese women: A double-blind, randomized, controlled trial. Menopause 2007;14:866-74 (Pubitemid 47517585)
    • (2007) Menopause , vol.14 , Issue.5 , pp. 866-874
    • Wu, J.1    Oka, J.2    Ezaki, J.3    Ohtomo, T.4    Ueno, T.5    Uchiyama, S.6    Toda, T.7    Uehara, M.8    Ishimi, Y.9
  • 39
    • 39149133683 scopus 로고    scopus 로고
    • Soy isoflavone intake increases bone mineral density in the spine of menopausal women: Meta-analysis of randomized controlled trials
    • Ma DF, Qin LQ, Wang PY, Katoh R. Soy isoflavone intake increases bone mineral density in the spine of menopausal women: Meta-analysis of randomized controlled trials. Clin Nutr 2008;27:57-64
    • (2008) Clin Nutr , vol.27 , pp. 57-64
    • Ma, D.F.1    Qin, L.Q.2    Wang, P.Y.3    Katoh, R.4
  • 40
    • 17844379469 scopus 로고    scopus 로고
    • One year soy protein supplementation has positive effects on bone formation markers but not bone density in postmenopausal women
    • Arjmandi BH, Lucas EA, Khalil DA, et al. One year soy protein supplementation has positive effects on bone formation markers but not bone density in postmenopausal women. Nutr J 2005;4:8.
    • (2005) Nutr J , vol.4 , pp. 8
    • Arjmandi, B.H.1    Lucas, E.A.2    Khalil, D.A.3
  • 41
    • 10944247894 scopus 로고    scopus 로고
    • Decreased bone resorption with soy isoflavone supplementation in postmenopausal women
    • Harkness LS, Fiedler K, Sehgal AR, Oravec D, Lermer E. Decreased bone resorption with soy isoflavones supplementation in postmenopausal women. J Womens Health 2004;13:1000-7 (Pubitemid 40017338)
    • (2004) Journal of Women's Health , vol.13 , Issue.9 , pp. 1000-1007
    • Harkness, L.S.1    Fiedler, K.2    Sehgal, A.R.3    Oravec, D.4    Lerner, E.5
  • 43
    • 4544248865 scopus 로고    scopus 로고
    • Soymilk or progesterone for prevention of bone loss: A 2 year randomized, placebo-controlled trial
    • DOI 10.1007/s00394-004-0497-8
    • Lydeking-Olsen E, Beck-Jensen JE, Setchell KD, Holm-Jensen T. Soymilk or progesterone for prevention of bone loss: A 2 year randomized, placebo-controlled trial. Eur J Nutr 2004;43: 246-57 (Pubitemid 39222536)
    • (2004) European Journal of Nutrition , vol.43 , Issue.4 , pp. 246-257
    • Lydeking-Olsen, E.1    Beck-Jensen, J.-E.2    Setchell, K.D.R.3    Holm-Jensen, T.4
  • 44
    • 0344873273 scopus 로고    scopus 로고
    • Evidence of Estrogenic Effect by the Three-Month-Intervention of Isoflavone on Vaginal Maturation and Bone Metabolism in Early Postmenopausal Women
    • DOI 10.1507/endocrj.50.613
    • Uesugi T, Toda T, Okuhira T Chen JT. Evidence of estrogenic effect by the three-month-intervention of isoflavone on vaginal maturation and bone metabolism in early postmenopausal women. Endocr J 2003;50:613-19 (Pubitemid 37442837)
    • (2003) Endocrine Journal , vol.50 , Issue.5 , pp. 613-619
    • Uesugi, T.1    Toda, T.2    Okuhira, T.3    Chen, J.-T.4
  • 45
    • 39149122124 scopus 로고    scopus 로고
    • Soy isoflavone intake attenuated bone loss in postmenopausal women
    • Yi YB, Shu YX. Soy isoflavone intake attenuated bone loss in postmenopausal women. Acta Nutr SINICA 2004;26:49-53
    • (2004) Acta Nutr SINICA , vol.26 , pp. 49-53
    • Yi, Y.B.1    Shu, Y.X.2
  • 46
    • 39149117640 scopus 로고    scopus 로고
    • The effect of soy isoflavone on bone metabolism in postmenopausal women
    • Gao YP, Li RH, Guo SZ. The effect of soy isoflavone on bone metabolism in postmenopausal women. J Shanxi Med Univ 2006;37:633-5
    • (2006) J Shanxi Med Univ , vol.37 , pp. 633-635
    • Gao, Y.P.1    Li, R.H.2    Guo, S.Z.3
  • 47
    • 63449093711 scopus 로고    scopus 로고
    • Effect of long-term intervention of soy isoflavones on bone mineral density in women: A meta-analysis of randomized controlled trials
    • Liu J, Ho SC, Su YX, Chen WQ, Zhang CX, Chen YM. Effect of long-term intervention of soy isoflavones on bone mineral density in women: A meta-analysis of randomized controlled trials. Bone 2009;44:948-53
    • (2009) Bone , vol.44 , pp. 948-953
    • Liu, J.1    Ho, S.C.2    Su, Y.X.3    Chen, W.Q.4    Zhang, C.X.5    Chen, Y.M.6
  • 48
    • 39049113293 scopus 로고    scopus 로고
    • Soy isoflavone intake inhibits bone resorption and stimulates bone formation in menopausal women: meta-analysis of randomized controlled trials
    • DOI 10.1038/sj.ejcn.1602748, PII 1602748
    • Ma DF, Qin LQ, Wang PY, Katoh R. Soy isoflavone intake inhibits bone resorption and stimulates bone formation in menopausal women: Meta-analysis of randomized controlled trials. Eur J Clin Nutr 2008;62:155-61 (Pubitemid 351234248)
    • (2008) European Journal of Clinical Nutrition , vol.62 , Issue.2 , pp. 155-161
    • Ma, D.-F.1    Qin, L.-Q.2    Wang, P.-Y.3    Katoh, R.4
  • 49
    • 33644964482 scopus 로고    scopus 로고
    • Cooperative effects of isoflavones and exercise on bone and lipid metabolism in postmenopausal Japanese women: A randomized placebo-controlled trial
    • Wu J, Oka J, Higuchi M, et al. Cooperative effects of isoflavones and exercise on bone and lipid metabolism in postmenopausal Japanese women: A randomized placebo-controlled trial. Metabolism 2006;55:423-33
    • (2006) Metabolism , vol.55 , pp. 423-433
    • Wu, J.1    Oka, J.2    Higuchi, M.3
  • 50
    • 25144490031 scopus 로고    scopus 로고
    • Prospective cohort study of soy food consumption and risk of bone fracture among postmenopausal women
    • DOI 10.1001/archinte.165.16.1890
    • Zhang X, Shu XO, Li H, et al. Prospective cohort study of soy food consumption and risk of bone fracture among postmenopausal women. Arch Intern Med 2005;165:1890-5 (Pubitemid 41352084)
    • (2005) Archives of Internal Medicine , vol.165 , Issue.16 , pp. 1890-1895
    • Zhang, X.1    Shu, X.-O.2    Li, H.3    Yang, G.4    Li, Q.5    Gao, Y.-T.6    Zheng, W.7


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