Ligand channeling within a G-protein-coupled receptor: The entry and exit of retinals in native opsin

Journal of Biological Chemistry

Volumn 278, Issue 27, 2003, Pages 24896-24903

  Schädel, Sandra A ^a   Heck, Martin ^a   Maretzki, Dieter ^a   Filipek, Slawomir ^b   Teller, David C ^c   Palczewski, Krzysztof ^d   Hofmann, Klaus Peter ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY OF WARSAW   (Poland)

^c UNIVERSITY OF WASHINGTON   (United States)

^d UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CRYSTAL STRUCTURE; HYDROLYSIS; HYDROPHOBICITY; LIPIDS; PROTEINS; QUENCHING;

LIGAND CHANNELING;

BIOCHEMISTRY;

11 CIS RETINAL; APOPROTEIN; G PROTEIN COUPLED RECEPTOR; OPSIN; RETINAL; RHODOPSIN; RHODOPSIN KINASE; LIGAND;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; COVALENT BOND; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; HYDROLYSIS; HYDROPHOBICITY; LIGAND BINDING; NONHUMAN; PHOTORECEPTOR; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN PHOSPHORYLATION; RETINA ROD OUTER SEGMENT; ANIMAL; CATTLE; CHEMISTRY; METABOLISM; X RAY CRYSTALLOGRAPHY;

ANIMALIA;

ANIMALS; CATTLE; CRYSTALLOGRAPHY, X-RAY; LIGANDS; OPSIN; PROTEIN CONFORMATION; RETINALDEHYDE; ROD OUTER SEGMENTS;

EID: 0042591319     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M302115200     Document Type: Article

References (38)

1. McBee, J. K., Palczewski, K., Baehr, W., and Pepperberg, D. R. (2001) Prog. Retin. Eye Res. 20, 469-529
2. Okada, T., Ernst, O. P., Palczewski, K., and Hofmann, K. P. (2001) Trends Biochem. Sci. 26, 318-324
3. Hofmann, K. P. (1999) Novartis Found Symp. 224, 158-175; discussion 175-180
4. Filipek, S., Stenkamp, R. E., Teller, D. C., and Palczewski, K. (2003) Annu. Rev. Physiol. 65, 851-879
5. DeGrip, W. J., DeLange, F., Klaassen, C. H., Verdegem, P. J., Wallace-Williams, S., Creemers, A. F., Bergo, V., Bovee, P. H., Raap, J., Rothschild, K. J., DeGroot, H. J., and Lugtenburg, J. (1999) Novartis Found Symp. 224, 102-118; discussion 118-123
6. Palczewski, K. (1997) Eur. J. Biochem. 248, 261-269
7. Pulvermüller, A., Palczewski, K., and Hofmann, K. P. (1993) Biochemistry 32, 14082-14088
8. Heck, M., Schädel, S. A., Maretzki, D., Bartl, F. J., Ritter, E., Palczewski, K., and Hofmann, K. P. (2003) J. Biol. Chem. 278, 3162-3169
9. Farrens, D. L., and Khorana, H. G. (1995) J. Biol. Chem. 270, 5073-5076
10. Palczewski, K., Jäger, S., Buczylko, J., Crouch, R. K., Bredberg, D. L., Hofmann, K. P., Asson-Batres, M. A., and Saari, J. C. (1994) Biochemistry 33, 13741-13750
11. Hofmann, K. P., Pulvermüller, A., Buczylko, J., Van Hooser, P., and Palczewski, K. (1992) J. Biol. Chem. 267, 15701-15706
12. Jäger, S., Palczewski, K., and Hofmann, K. P. (1996) Biochemistry 35, 2901-2908
13. Sachs, K., Maretzki, D., and Hofmann, K. P. (2000) Methods Enzymol. 315, 238-251
14. Sachs, K., Maretzki, D., Meyer, C. K., and Hofmann, K. P. (2000) J. Biol. Chem. 275, 6189-6194
15. Teller, D. C., Okada, T., Behnke, C. A., Palczewski, K., and Stenkamp, R. E. (2001) Biochemistry 40, 7761-7772
16. Palczewski, K., Kumasaka, T., Hori, T., Behnke, C. A., Motoshima, H., Fox, B. A., Le Trong, I., Teller, D. C., Okada, T., Stenkamp, R. E., Yamamoto, M., and Miyano, M. (2000) Science 289, 739-745
17. Papermaster, D. S. (1982) Methods Enzymol. 81, 48-52
18. Kühn, H., and Wilden, U. (1982) Methods Enzymol. 81, 489-496
19. Surya, A., Foster, K. W., and Knox, B. E. (1995) J. Biol. Chem. 270, 5024-5031
20. Sali, A., Potterton, L., Yuan, F., van Vlijmen, H., and Karplus, M. (1995) Proteins 23, 318-326
21. Bowie, J. U., Luthy, R., and Eisenberg, D. (1991) Science 253, 164-170
22. Ebrey, T. G. (1972) Photochem. Photobiol. 15, 585-588
23. Ebrey, T. G. (1971) Proc. Natl. Acad. Sci. U. S. A. 68, 713-716
24. Fukada, Y., and Yoshizawa, T. (1981) Biochim. Biophys. Acta 675, 195-200
25. Cohen, G. B., Oprian, D. D., and Robinson, P. R. (1992) Biochemistry 31, 12592-12601
26. Cohen, G. B., Yang, T., Robinson, P. R., and Oprian, D. D. (1993) Biochemistry 32, 6111-6115
27. Kandori, H., Shichida, Y., and Yoshizawa, T. (2001) Biochemistry (Mosc.) 66, 1197-1209
28. Kawamura, S., Wakabayashi, S., Maeda, A., and Yoshizawa, T. (1978) Vision Res. 18, 457-462
29. Sun, H., and Nathans, J. (2001) J. Bioenerg. Biomembr. 33, 523-530
30. Palczewski, K., Van Hooser, J. P., Garwin, G. G., Chen, J., Liou, G. I., and Saari, J. C. (1999) Biochemistry 38, 12012-12019
31. Matsumoto, H., and Yoshizawa, T. (1978) Vision Res. 18, 607-609
32. Daemen, F. J. (1978) Nature 276, 847-848
33. Jang, G. F., Kuksa, V., Filipek, S., Bartl, F., Ritter, E., Gelb, M. H., Hofmann, K. P., and Palczewski, K. (2001) J. Biol. Chem. 276, 26148-26153
34. Kefalov, V. J., Crouch, R. K., and Cornwall, M. C. (2001) Neuron 29, 749-755
35. Buczylko, J., Saari, J. C., Crouch, R. K., and Palczewski, K. (1996) J. Biol. Chem. 271, 20621-20630
36. Roderick, S. L., Chan, W. W., Agate, D. S., Olsen, L. R., Vetting, M. W., Rajashankar, K. R., and Cohen, D. E. (2002) Nat. Struct. Biol. 9, 507-511
37. Sakmar, T. P., Franke, R. R., and Khorana, H. G. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 8309-8313
38. Saam, J., Tajkhorshid, E., Hayashi, S., and Schulten, K. (2002) Biophys. J. 83, 3097-3112