Antimalarial activity and toxicity evaluation of a quantified Nauclea pobeguinii extract

Journal of Ethnopharmacology

Volumn 131, Issue 1, 2010, Pages 10-16

  Mesia, Kahunu ^a,b   Cimanga, Richard K ^a,b   Dhooghe, Liene ^b   Cos, Paul ^b   Apers, Sandra ^b   Totté, Jozef ^b   Tona, Gaston L ^a   Pieters, Luc ^b   Vlietinck, Arnold J ^b   Maes, Louis ^b  

^a UNIVERSITY OF KINSHASA   (Congo)

^b UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

Antiplasmodial activity; Malaria; Nauclea pobeguinii; Rubiaceae; Strictosamide

Indexed keywords

19 O METHYLANGUSTOLINE; 3 KETOQUINOVIC ACID; 3 O BETA FUCOSYLQUINOVIC ACID; 5 CARBOXYSTRICTOSIDINE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CREATININE; NAUCLEA POBEGUINII EXTRACT; PLANT EXTRACT; STRICTOSAMIDE; UNCLASSIFIED DRUG; UREA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ARTICLE; BARK; CARBON NUCLEAR MAGNETIC RESONANCE; CONGO; CYTOTOXICITY; DRUG STRUCTURE; FEMALE; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; MALARIA; MALE; MEDICINAL PLANT; MOUSE; NAUCLEA POBEGUINII; NONHUMAN; PARASITEMIA; PHYTOCHEMISTRY; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; PLASMODIUM YOELII; PROTON NUCLEAR MAGNETIC RESONANCE; RUBIACEAE; SINGLE DRUG DOSE; SURVIVAL TIME; TRADITIONAL MEDICINE;

ACUTE TOXICITY TESTS; ANIMALS; ANTIMALARIALS; CELLS, CULTURED; DRUG EVALUATION, PRECLINICAL; FEMALE; HUMANS; MICE; PLANT BARK; PLANT EXTRACTS; PLANT STEMS; PLASMODIUM FALCIPARUM; RANDOM ALLOCATION; RUBIACEAE;

MUS; NAUCLEA; PLASMODIUM FALCIPARUM; RUBIACEAE;

EID: 77955340711     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2010.05.008     Document Type: Article

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