메뉴 건너뛰기




Volumn 406, Issue 3, 2011, Pages 311-314

A novel approach to overcome temozolomide resistance in glioma and melanoma: Inactivation of MGMT by gene therapy

Author keywords

Conditionally replicating adenoviruses; Gene therapy; Glioma; Melanoma; MGMT; TMZ

Indexed keywords

BETA INTERFERON; INTERLEUKIN 24; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; PROTEIN P53; TEMOZOLOMIDE;

EID: 79952739967     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.02.042     Document Type: Short Survey
Times cited : (49)

References (46)
  • 8
    • 0030993717 scopus 로고    scopus 로고
    • Temozolomide: a review of its discovery, chemical properties, pre-clinical development and clinical trials
    • Newlands E.S., Stevens M.F., Wedge S.R., Wheelhouse R.T., Brock C. Temozolomide: a review of its discovery, chemical properties, pre-clinical development and clinical trials. Cancer Treat. Rev. 1997, 23:35-61.
    • (1997) Cancer Treat. Rev. , vol.23 , pp. 35-61
    • Newlands, E.S.1    Stevens, M.F.2    Wedge, S.R.3    Wheelhouse, R.T.4    Brock, C.5
  • 10
    • 0037010048 scopus 로고    scopus 로고
    • Systemic chemotherapy for the treatment of metastatic melanoma
    • Li Y., McClay E.F. Systemic chemotherapy for the treatment of metastatic melanoma. Semin. Oncol. 2002, 29:413-426.
    • (2002) Semin. Oncol. , vol.29 , pp. 413-426
    • Li, Y.1    McClay, E.F.2
  • 13
    • 0030911619 scopus 로고    scopus 로고
    • Effect of single and multiple administration of an O6-benzylguanine/temozolomide combination: an evaluation in a human melanoma xenograft model
    • Wedge S.R., Porteous J.K., Newlands E.S. Effect of single and multiple administration of an O6-benzylguanine/temozolomide combination: an evaluation in a human melanoma xenograft model. Cancer Chemother. Pharmacol. 1997, 40:266-272.
    • (1997) Cancer Chemother. Pharmacol. , vol.40 , pp. 266-272
    • Wedge, S.R.1    Porteous, J.K.2    Newlands, E.S.3
  • 14
    • 33751074140 scopus 로고    scopus 로고
    • Targeting gene-virotherapy of cancer and its prosperity
    • Liu X.Y. Targeting gene-virotherapy of cancer and its prosperity. Cell Res. 2006, 16:879-886.
    • (2006) Cell Res. , vol.16 , pp. 879-886
    • Liu, X.Y.1
  • 15
    • 67349228816 scopus 로고    scopus 로고
    • Armed replicating adenoviruses for cancer virotherapy
    • Cody J.J., Douglas J.T. Armed replicating adenoviruses for cancer virotherapy. Cancer Gene Ther. 2009, 16:473-488.
    • (2009) Cancer Gene Ther. , vol.16 , pp. 473-488
    • Cody, J.J.1    Douglas, J.T.2
  • 16
    • 31544464704 scopus 로고    scopus 로고
    • Targeted modulation of MGMT: clinical implications
    • Liu L., Gerson S.L. Targeted modulation of MGMT: clinical implications. Clin. Cancer Res. 2006, 12:328-331.
    • (2006) Clin. Cancer Res. , vol.12 , pp. 328-331
    • Liu, L.1    Gerson, S.L.2
  • 17
    • 57749115016 scopus 로고    scopus 로고
    • Interleukin-24 overcomes temozolomide resistance and enhances cell death by down-regulation of O6-methylguanine-DNA methyltransferase in human melanoma cells
    • Zheng M., Bocangel D., Ramesh R., Ekmekcioglu S., Poindexter N., Grimm E.A., Chada S. Interleukin-24 overcomes temozolomide resistance and enhances cell death by down-regulation of O6-methylguanine-DNA methyltransferase in human melanoma cells. Mol. Cancer Ther. 2008, 7:3842-3851.
    • (2008) Mol. Cancer Ther. , vol.7 , pp. 3842-3851
    • Zheng, M.1    Bocangel, D.2    Ramesh, R.3    Ekmekcioglu, S.4    Poindexter, N.5    Grimm, E.A.6    Chada, S.7
  • 19
    • 58749097764 scopus 로고    scopus 로고
    • Temozolomide- and fotemustine-induced apoptosis in human malignant melanoma cells: response related to MGMT, MMR, DSBs, and p53
    • Naumann S.C., Roos W.P., Jost E., Belohlavek C., Lennerz V., Schmidt C.W., Christmann M., Kaina B. Temozolomide- and fotemustine-induced apoptosis in human malignant melanoma cells: response related to MGMT, MMR, DSBs, and p53. Br. J. Cancer 2009, 100:322-333.
    • (2009) Br. J. Cancer , vol.100 , pp. 322-333
    • Naumann, S.C.1    Roos, W.P.2    Jost, E.3    Belohlavek, C.4    Lennerz, V.5    Schmidt, C.W.6    Christmann, M.7    Kaina, B.8
  • 20
    • 33947611627 scopus 로고    scopus 로고
    • Perspectives in biomolecular therapeutic intervention in cancer: from the early to the new strategies with type I interferons
    • Vannucchi S., Chiantore M.V., Mangino G., Percario Z.A., Affabris E., Fiorucci G., Romeo G. Perspectives in biomolecular therapeutic intervention in cancer: from the early to the new strategies with type I interferons. Curr. Med. Chem. 2007, 14:667-679.
    • (2007) Curr. Med. Chem. , vol.14 , pp. 667-679
    • Vannucchi, S.1    Chiantore, M.V.2    Mangino, G.3    Percario, Z.A.4    Affabris, E.5    Fiorucci, G.6    Romeo, G.7
  • 21
    • 26844476755 scopus 로고    scopus 로고
    • Therapeutic implications of interferon regulatory factor (IRF)-1 and IRF-2 in diffusely infiltrating astrocytomas (DIA): response to interferon (IFN)-beta in glioblastoma cells and prognostic value for DIA
    • Yoshino A., Katayama Y., Yokoyama T., Watanabe T., Ogino A., Ota T., Komine C., Fukushima T., Kusama K. Therapeutic implications of interferon regulatory factor (IRF)-1 and IRF-2 in diffusely infiltrating astrocytomas (DIA): response to interferon (IFN)-beta in glioblastoma cells and prognostic value for DIA. J. Neurooncol. 2005, 74:249-260.
    • (2005) J. Neurooncol. , vol.74 , pp. 249-260
    • Yoshino, A.1    Katayama, Y.2    Yokoyama, T.3    Watanabe, T.4    Ogino, A.5    Ota, T.6    Komine, C.7    Fukushima, T.8    Kusama, K.9
  • 24
    • 24744452216 scopus 로고    scopus 로고
    • IFN-beta down-regulates the expression of DNA repair gene MGMT and sensitizes resistant glioma cells to temozolomide
    • Natsume A., Ishii D., Wakabayashi T., Tsuno T., Hatano H., Mizuno M., Yoshida J. IFN-beta down-regulates the expression of DNA repair gene MGMT and sensitizes resistant glioma cells to temozolomide. Cancer Res. 2005, 65:7573-7579.
    • (2005) Cancer Res. , vol.65 , pp. 7573-7579
    • Natsume, A.1    Ishii, D.2    Wakabayashi, T.3    Tsuno, T.4    Hatano, H.5    Mizuno, M.6    Yoshida, J.7
  • 27
    • 28544435618 scopus 로고    scopus 로고
    • Is mda-7/IL-24 a " magic bullet" for cancer?
    • Fisher P.B. Is mda-7/IL-24 a " magic bullet" for cancer?. Cancer Res. 2005, 65:10128-10138.
    • (2005) Cancer Res. , vol.65 , pp. 10128-10138
    • Fisher, P.B.1
  • 28
    • 0036674617 scopus 로고    scopus 로고
    • Live or let die: the cell's response to p53
    • Vousden K.H., Lu X. Live or let die: the cell's response to p53. Nat. Rev. Cancer 2002, 2:594-604.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 594-604
    • Vousden, K.H.1    Lu, X.2
  • 30
    • 0031987277 scopus 로고    scopus 로고
    • Regulation of p53 downstream genes
    • el-Deiry W.S. Regulation of p53 downstream genes. Semin. Cancer Biol. 1998, 8:345-357.
    • (1998) Semin. Cancer Biol. , vol.8 , pp. 345-357
    • el-Deiry, W.S.1
  • 31
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • Miyashita T., Reed J.C. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 1995, 80:293-299.
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 32
    • 33846252663 scopus 로고    scopus 로고
    • Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine
    • Roos W.P., Batista L.F., Naumann S.C., Wick W., Weller M., Menck C.F., Kaina B. Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine. Oncogene 2007, 26:186-197.
    • (2007) Oncogene , vol.26 , pp. 186-197
    • Roos, W.P.1    Batista, L.F.2    Naumann, S.C.3    Wick, W.4    Weller, M.5    Menck, C.F.6    Kaina, B.7
  • 33
    • 0030611436 scopus 로고    scopus 로고
    • Inhibition of O6-alkylguanine DNA-alkyltransferase or poly(ADP-ribose) polymerase increases susceptibility of leukemic cells to apoptosis induced by temozolomide
    • Tentori L., Orlando L., Lacal P.M., Benincasa E., Faraoni I., Bonmassar E., D'Atri S., Graziani G. Inhibition of O6-alkylguanine DNA-alkyltransferase or poly(ADP-ribose) polymerase increases susceptibility of leukemic cells to apoptosis induced by temozolomide. Mol. Pharmacol. 1997, 52:249-258.
    • (1997) Mol. Pharmacol. , vol.52 , pp. 249-258
    • Tentori, L.1    Orlando, L.2    Lacal, P.M.3    Benincasa, E.4    Faraoni, I.5    Bonmassar, E.6    D'Atri, S.7    Graziani, G.8
  • 34
    • 33645105856 scopus 로고    scopus 로고
    • O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells
    • Hermisson M., Klumpp A., Wick W., Wischhusen J., Nagel G., Roos W., Kaina B., Weller M. O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells. J. Neurochem. 2006, 96:766-776.
    • (2006) J. Neurochem. , vol.96 , pp. 766-776
    • Hermisson, M.1    Klumpp, A.2    Wick, W.3    Wischhusen, J.4    Nagel, G.5    Roos, W.6    Kaina, B.7    Weller, M.8
  • 35
    • 34250802722 scopus 로고    scopus 로고
    • O6-methylguanine-DNA methyltransferase is downregulated in transformed astrocyte cells: implications for anti-glioma therapies
    • Sasai K., Akagi T., Aoyanagi E., Tabu K., Kaneko S., Tanaka S. O6-methylguanine-DNA methyltransferase is downregulated in transformed astrocyte cells: implications for anti-glioma therapies. Mol. Cancer 2007, 6:36.
    • (2007) Mol. Cancer , vol.6 , pp. 36
    • Sasai, K.1    Akagi, T.2    Aoyanagi, E.3    Tabu, K.4    Kaneko, S.5    Tanaka, S.6
  • 36
    • 0029936652 scopus 로고    scopus 로고
    • Wild-type p53 suppresses transcription of the human O6-methylguanine-DNA methyltransferase gene
    • Harris L.C., Remack J.S., Houghton P.J., Brent T.P. Wild-type p53 suppresses transcription of the human O6-methylguanine-DNA methyltransferase gene. Cancer Res. 1996, 56:2029-2032.
    • (1996) Cancer Res. , vol.56 , pp. 2029-2032
    • Harris, L.C.1    Remack, J.S.2    Houghton, P.J.3    Brent, T.P.4
  • 37
    • 0034901404 scopus 로고    scopus 로고
    • Enforced expression of wild-type p53 curtails the transcription of the O(6)-methylguanine-DNA methyltransferase gene in human tumor cells and enhances their sensitivity to alkylating agents
    • Srivenugopal K.S., Shou J., Mullapudi S.R., Lang F.F., Rao J.S., Ali-Osman F. Enforced expression of wild-type p53 curtails the transcription of the O(6)-methylguanine-DNA methyltransferase gene in human tumor cells and enhances their sensitivity to alkylating agents. Clin. Cancer Res. 2001, 7:1398-1409.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 1398-1409
    • Srivenugopal, K.S.1    Shou, J.2    Mullapudi, S.R.3    Lang, F.F.4    Rao, J.S.5    Ali-Osman, F.6
  • 38
    • 71949113556 scopus 로고    scopus 로고
    • P53-Mediated down-regulation of the human DNA repair gene O6-methylguanine-DNA methyltransferase (MGMT) via interaction with Sp1 transcription factor
    • Bocangel D., Sengupta S., Mitra S., Bhakat K.K. P53-Mediated down-regulation of the human DNA repair gene O6-methylguanine-DNA methyltransferase (MGMT) via interaction with Sp1 transcription factor. Anticancer Res. 2009, 29:3741-3750.
    • (2009) Anticancer Res. , vol.29 , pp. 3741-3750
    • Bocangel, D.1    Sengupta, S.2    Mitra, S.3    Bhakat, K.K.4
  • 39
    • 0037062951 scopus 로고    scopus 로고
    • RNA interference
    • Hannon G.J. RNA interference. Nature 2002, 418:244-251.
    • (2002) Nature , vol.418 , pp. 244-251
    • Hannon, G.J.1
  • 40
    • 77955519631 scopus 로고    scopus 로고
    • Oncolytic-adenovirus-expressed RNA interference for cancer therapy
    • Pei D.S., Di J.H., Chen F.F., Zheng J.N. Oncolytic-adenovirus-expressed RNA interference for cancer therapy. Expert Opin. Biol. Ther. 2010, 10:1331-1341.
    • (2010) Expert Opin. Biol. Ther. , vol.10 , pp. 1331-1341
    • Pei, D.S.1    Di, J.H.2    Chen, F.F.3    Zheng, J.N.4
  • 42
    • 0034927057 scopus 로고    scopus 로고
    • Replication-selective virotherapy for cancer: Biological principles, risk management and future directions
    • Kirn D., Martuza R.L., Zwiebel J. Replication-selective virotherapy for cancer: Biological principles, risk management and future directions. Nat. Med. 2001, 7:781-787.
    • (2001) Nat. Med. , vol.7 , pp. 781-787
    • Kirn, D.1    Martuza, R.L.2    Zwiebel, J.3
  • 43
    • 39149095268 scopus 로고    scopus 로고
    • Enhanced antitumor activity by a selective conditionally replicating adenovirus combining with MDA-7/interleukin-24 for B-lymphoblastic leukemia via induction of apoptosis
    • Qian W., Liu J., Tong Y., Yan S., Yang C., Yang M., Liu X. Enhanced antitumor activity by a selective conditionally replicating adenovirus combining with MDA-7/interleukin-24 for B-lymphoblastic leukemia via induction of apoptosis. Leukemia 2008, 22:361-369.
    • (2008) Leukemia , vol.22 , pp. 361-369
    • Qian, W.1    Liu, J.2    Tong, Y.3    Yan, S.4    Yang, C.5    Yang, M.6    Liu, X.7
  • 44
    • 37549007090 scopus 로고    scopus 로고
    • Adenovirus-based strategies overcome temozolomide resistance by silencing the O6-methylguanine-DNA methyltransferase promoter
    • Alonso M.M., Gomez-Manzano C., Bekele B.N., Yung W.K., Fueyo J. Adenovirus-based strategies overcome temozolomide resistance by silencing the O6-methylguanine-DNA methyltransferase promoter. Cancer Res. 2007, 67:11499-11504.
    • (2007) Cancer Res. , vol.67 , pp. 11499-11504
    • Alonso, M.M.1    Gomez-Manzano, C.2    Bekele, B.N.3    Yung, W.K.4    Fueyo, J.5
  • 46
    • 78650173536 scopus 로고    scopus 로고
    • Down-regulation of O6-methylguanine-DNA methyl transferase enhances the effect of temozolomide in melanoma cells
    • Jiang G., Zheng J.N., Liu Y.Q. Down-regulation of O6-methylguanine-DNA methyl transferase enhances the effect of temozolomide in melanoma cells. Med. Hypotheses 2011, 76:147-148.
    • (2011) Med. Hypotheses , vol.76 , pp. 147-148
    • Jiang, G.1    Zheng, J.N.2    Liu, Y.Q.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.