Tryptanthrin inhibits Th2 development, and IgE-mediated degranulation and IL-4 production by rat basophilic leukemia RBL-2H3 cells

Journal of Ethnopharmacology

Volumn 134, Issue 2, 2011, Pages 450-459

  Iwaki, Kanso ^a   Ohashi, Emiko ^a   Arai, Norie ^a   Kohno, Keizo ^a   Ushio, Shimpei ^a   Taniguchi, Makoto ^b   Fukuda, Shigeharu ^a  

^a HAYASHIBARA BIOCHEMICAL LABORATORIES INC   (Japan)

^b Mimasaka University   (Japan)

Author keywords

Degranulation; Interleukin 4 (IL 4); RBL 2H3 cells; T helper type 2 (Th2) cells; Tryptanthrin; Type I allergy

Indexed keywords

ANTIALLERGIC AGENT; CD3 ANTIBODY; GAMMA INTERFERON; IMMUNOGLOBULIN E; INTERLEUKIN 4; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; TRANSCRIPTION FACTOR C MAF; TRANSCRIPTION FACTOR GATA 3; TRYPTANTHRIN; UNCLASSIFIED DRUG;

ALLERGIC REACTION; ANIMAL CELL; ARTICLE; BAGG ALBINO MOUSE; BASOPHIL; CD4+ T LYMPHOCYTE; CELL CLONE; CELL DIFFERENTIATION; CELL EXPANSION; CELL MATURATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DOWN REGULATION; DRUG MECHANISM; EFFECTOR CELL; ENZYME PHOSPHORYLATION; FEMALE; IMMEDIATE TYPE HYPERSENSITIVITY; IN VITRO STUDY; MAST CELL DEGRANULATION; MAST CELL LEUKEMIA; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPIC VARIATION; PROTEIN EXPRESSION; RAT; SPLEEN CELL; TH1 CELL; TH2 CELL;

ANIMALS; ANTI-ALLERGIC AGENTS; ANTIGENS, PLANT; BASOPHILS; CELL DEGRANULATION; CELL DIFFERENTIATION; CELL LINE, TUMOR; DOWN-REGULATION; FEMALE; HYPERSENSITIVITY; IMMUNOGLOBULIN E; INTERLEUKIN-4; LEUKEMIA, BASOPHILIC, ACUTE; MAST CELLS; MICE; MICE, INBRED BALB C; PHOSPHORYLATION; PHYTOTHERAPY; PLANT EXTRACTS; POLYGONUM; PROTO-ONCOGENE PROTEINS C-MAF; QUINAZOLINES; RATS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TH2 CELLS;

MUS; POLYGONUM TINCTORIUM; RATTUS;

EID: 79952704411     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2010.12.041     Document Type: Article

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