Eicosapentaenoic acid ameliorates diabetic nephropathy of type 2 diabetic KKAy/Ta mice: Involvement of MCP-1 suppression and decreased ERK1/2 and p38 phosphorylation

Nephrology Dialysis Transplantation

Volumn 21, Issue 3, 2006, Pages 605-615

  Hagiwara, Shinji ^a   Makita, Yuichiro ^a   Gu, Leyi ^a   Tanimoto, Mitsuo ^a   Zhang, Minfang ^a   Nakamura, Shinji ^a   Kaneko, Shigeru ^a   Itoh, Takamichi ^a   Gohda, Tomohito ^a   Horikoshi, Satoshi ^a   Tomino, Yasuhiko ^a  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

2; Diabetic nephropathy; EPA; ERK1 ; KKAy ; MCP 1; PDGF; Ta mice

Indexed keywords

ALBUMIN; ICOSAPENTAENOIC ACID ETHYL ESTER; LEPTIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; PHOSPHATIDYLINOSITOL 3 KINASE; STRESS ACTIVATED PROTEIN KINASE; TRIACYLGLYCEROL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; DIABETIC NEPHROPATHY; DOWN REGULATION; DRUG DOSE REGIMEN; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR MATRIX; GLUCOSE INTOLERANCE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; KIDNEY FIBROSIS; MALE; MESANGIUM CELL; MOUSE; MOUSE STRAIN; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRIACYLGLYCEROL BLOOD LEVEL; URINALYSIS; WESTERN BLOTTING;

ANIMALS; CELLS, CULTURED; CHEMOKINE CCL2; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; EICOSAPENTAENOIC ACID; IMMUNOHISTOCHEMISTRY; KIDNEY GLOMERULUS; MALE; MESANGIAL CELLS; MICE; MICE, OBESE; MITOGEN-ACTIVATED PROTEIN KINASE 1; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TREATMENT OUTCOME;

EID: 33644869129     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfi208     Document Type: Article

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