Effect of octreotide, captopril or insulin on renal changes and UAE in long-term experimental diabetes

Kidney International

Volumn 53, Issue 1, 1998, Pages 173-180

  Grønbæk, Henning ^a   Vogel, Ioa ^b   Østerby, Ruth ^b   Lancranjan, Ioana ^b   Flyvbjerg, Allan ^b   Ørskov, Hans ^b  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b NONE

Author keywords

Captopril; Diabetes; IGF I; Insulin; Kidney morphology; Octreotide; Renal hypertrophy; Urinary albumin excretion

Indexed keywords

ACETIC ACID; ALBUMIN; BOVINE INSULIN; CAPTOPRIL; GLUCOSE; INSULIN ZINC SUSPENSION; OCTREOTIDE; PLACEBO; SOMATOMEDIN C; STREPTOZOCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; FEMALE; GLOMERULUS; KIDNEY SIZE; NONHUMAN; PRIORITY JOURNAL; PROTEINURIA; RAT; STREPTOZOCIN DIABETES; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0031887860     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.1998.00720.x     Document Type: Article

References (39)

1. FLYVBJERG A: The role of insulin-like growth factor I in initial renal hypertrophy in experimental diabetes, in Growth Hormone and Insulin-Like Growth Factor I in Human and Experimental Diabetes, edited by FLYVBJERG A, ØRSKOV H, ALBERTI KGMM, Chichester, John Wiley & Sons, 1993, p 271
2. GRØNBÆK H, NIELSEN B, ØSTERBY R, HARRIS AG, ØRSKOV H, FLYVBJERG A: Effect of octreotide and insulin on manifest renal and glomerular hypertrophy and urinary albumin excretion in long-term experimental diabetes in rats. Diabetologia 38:135-144, 1995
3. ZATZ R, DUNN R, MEYER TW, ANDERSON S, RENNKE HG, BRENNER BM, TROY JL, DEGRAPHENRIED RL, NUNN AW, SANDSTRÖM D: Prevention of diabetic glomerulopathy by pharmacological amelioration of glomerulary capillary hypertension. J Clin Invest 77:1925-1930, 1986
4. MYERS BD, MEYER TW: Angiotensin converting enzyme inhibitors in the prevention of experimental diabetic glomerulopathy. Am J Kidney Dis 13:20-24, 1989
5. ANDERSON S: Effects of angiotensin converting enzyme inhibitors in experimental diabetes. J Am Soc Nephrol 1:S51-S54, 1990
6. WOLF G, HABERSTROH U, NEILSON EG: Angiotensin-II stimulates the proliferation and biosynthesis of type-I collagen in cultured murine mesangial cells. Am J Pathol 140:95-107, 1992
7. TAKASAKI I, CHOVANIAN AV, SARZANI R, BRECHER P: Effect of hypertension on fibronectin expression in the rat aorta. J Biol Chem 265:21935-21939, 1990
8. HIRSCHBERG R, KOPPLE JD: Insulin-like growth factor I and renal function. Diabetes Rev 3:177-195, 1995
9. BACH LA, RECHLER MM: Insulin-like growth factor binding proteins. Diabetes Rev 3:38-61, 1995
10. FLYVBJERG A, LANDAU D, DOMENE H, HERNANDEZ L, GRØNBÆK H, LEROITH D: The role of growth hormone, insulin-like growth factors (IGFs), and IGF-binding proteins in experimental diabetic kidney disease. Metabolism 44:67-71, 1995
11. FLYVBJERG A, MARSHALL SM, FRYSTYK J, HANSEN KW, HARRIS AG, ØRSKOV H: Octreotide administration in diabetic rats: Effects on renal hypertrophy and urinary albumin excretion. Kidney Int 41:805-812, 1992
12. GRØNBÆK H, VOLMERS P, BJØRN SF, ØSTERBY R, ØRSKOV H, FLYVBJERG A: Effect of GH/IGF-1 deficiency on long-term renal changes and urinary albumin excretion in diabetic dwarf rats. Am J Physiol 272:E918-E924, 1997
13. FLYVBJERG A, FRYSTYK J, THORLACIUS-USSING O, ØRSKOV H: Somatostatin analogue administration prevents increase in kidney somatomedin C and initial renal growth in diabetic and uninephrectomized rats. Diabetologia 32:261-265, 1989
14. GRØNBÆK H, NIELSIN B, FRYSTYK J, FLYVBJERG A, ØRSKOV H: Effect of lanreotide on local kidney IGF-I and renal growth in experimental diabetes in the rat. Exp Nephrol 4:295-303, 1996
15. PFEFFER JM, PFEFFER MA, FROHLICH ED: Validity of an indirect tail-cuff method for determining systolic arterial pressure in unanesthetized normotensive and spontaneously hypertensive rats. J Lab Clin Med 78:957-962, 1971
16. GUNDERSEN HJG, BENDTSEN TF, KORBO L, MARCUSSEN N, MØLLER A, NIELSEN K, NYENGAARD JR, PAKKENBERG B, SØRENSEN FB, VESTERBY A, WEST MJ: Some new, simple and efficient stereological methods and their use in pathological research and diagnosis. APMIS 96:379-394, 1988
17. GUNDERSEN HJG, BAGGER P, BENDTSEN TF, EVANS SM, KORBO L, MARCUSSEN N, MØLLER A, NIELSEN K, NYENGAARD JR, PAKKENBERG B, SØRENSEN FB, VESTERBY A, WEST MJ: The new stereological tools: Disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis. APMIS 96:857-881, 1988
18. D'ERCOLE AJ, STILES AD, UNDERWOOD LE: Tissue concentrations of somatomedin C: Further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of action. Proc Natl Acad Sci USA 81:935-939, 1984
19. GRØNBÆK H, FRYSTYK J, ØRSKOV H, FLYVBJERG A: Effect of sodium selenite on growth, insulin-like growth factor binding proteins, and insulin-like growth factor I in rats. J Endocrinol 145:105-112, 1995
20. CHRISTENSEN CK, ØRSKOV C: Rapid screening PEG radioimmunoassay for quantification of pathological microalbuminuria. Diabetic Nephrol 3:92-94, 1984
21. WOLF G, NEILSON EG, GOLDFARB S, ZIYADEH FN: The influence of glucose concentration on angiotensin II-induced hypertrophy of proximal tubular cells in culture. Biochem Biophys Res Commun 176:902-909, 1991
22. RAY PE, AGUILERA G, KOPP JB, HORIKOSHI S, KLOTMAN PE: Angiotensin II receptor-mediated proliferation of cultured human fetal mesangial cells. Kidney Int 40:764-771, 1991
23. NEW JP, CANAVAN JP, FLYVBJERG A, HAMON G, BILOUS RW, MARSHALL SM: Renal enlargement and insulin-like growth factor-1 accumulation in the Wistar rat model of experimental diabetes is not prevented by angiotensin converting enzyme inhibition. Diabetologia 39:166-171, 1996
24. ZATZ R, DUNN BR, MEYER TW, ANDERSON TW, RENNKE HG, BRENNER BM: Prevention of diabetic glomerulopathy by pharmacological amelioration of glomerular capillary hypertension. J Clin Invest 77:1925-1930, 1986
25. HAJNAZARIAN M, COSIO FG, NAHMAN NS, MAHAN JD: Angiotensin-converting enzyme inhibition partially prevents diabetic organomegaly. Am J Kidney Dis 23:105-117, 1994
26. GRØNBÆK H, NIELSEN B, FRYSTYK J, ØRSKOV H, FLYVBJERG A: Effect of octreotide on experimental diabetic renal and glomerular growth: Importance of early intervention. J Endocrinol 147:95-102, 1995
27. WEISS O, RUBINGER D, NEPHESH I, MOSHE R, RAZ I: The influence of octreotide on IGF system gene expression in the kidney of diabetic rats. (abstract) Diabetologia 38:A206, 1995
28. VORA J, OWENS DR, LUZIO SD, ATIEA J, RYDER R, HAYES TM: Renal response to intravenous somatostatin in insulin-dependent diabetic patients and normal subjects. J Clin Endocrinol Metab 64:975-979, 1987
29. PEDERSEN MM, CHRISTENSEN SE, CHRISTIANSEN JS, PEDERSEN EB, MOGENSEN CE, ØRSKOV H: Acute effects of a somatostatin analogue on kidney function in type 1 diabetic patients. Diabetic Med 7:304-309, 1990
30. SERRI O, BEAUREGARD H, BRAZEAU P, ABRIBAT T, LAMBERT J, HARRIS A, VACHON L: Somatostatin analogue, octreotide, reduces increased glomerular filtration rate and kidney size in insulin-dependent diabetes. JAMA 265:888-892, 1991
31. HIRSCHBERG R, KOPPLE JD: Evidence that insulin-like growth factor I increases renal plasma flow and glomerular filtration rate in fasted rats. J Clin Invest 83:326-330, 1989
32. RASCH R: Prevention of diabetic glomerulopathy in streptozotocin diabetic rats by insulin treatment: Kidney size and glomerular volume. Diabetologia 16:125-128, 1979
33. RASCH R: Prevention of diabetic glomerulopathy in streptozotocin diabetic rats by insulin treatment: Glomerular basement membrane thickness. Diabetologia 16:319-324, 1979
34. STACKHOUSE S, MILLER PL, PARK SK, MEYER TW: Reversal of glomerular hyperfiltration and renal hypertrophy by blood glucose normalization in diabetic rats. Diabetes 39:989-995, 1990
35. NYENGAARD JR, FLYVBJERG A, RASCH R: The impact of renal growth, regression and regrowth in experimental diabetes mellitus on number and size of proximal and distal tubular cells in the rat kidney. Diabetologia 36:1126 -1131, 1993
36. ØSTERBY R, GUNDERSEN HJG, CHRISTENSEN NJ: The acute effect of insulin on capillary endothelial cells. Diabetes 27:745-749, 1978
37. MOGENSEN CE, CHRISTENSEN NJ, GUNDERSEN HJG: The acute effect of insulin on renal haemodynamics and protein excretion in diabetics. Diabetologia 15:153-157, 1978
38. FLYVBJERG A, THORLACIUS-USSING O, NÆRAA R, INGERSLEV J, ØRSKOV H: Kidney tissue somatomedin C and initial renal growth in diabetic and uninephrectomized rats. Diabetologia 31:310-314, 1988
39. FLYVBJERG A, BORNFELDT KE, MARSHALL SM, ARNOVIST HJ, ØRSKOV H: Kidney IGF-I mRNA in initial renal hypertrophy in experimental diabetes in rats. Diabetologia 33:334-338, 1990