Amphiphilic, low molecular weight poly(ethylene imine) derivatives with enhanced stability for efficient pulmonary gene delivery

Journal of Gene Medicine

Volumn 13, Issue 2, 2011, Pages 123-133

  Roesler, Susanne ^a,b   Koch, Felix P V ^a   Schmehl, Thomas ^b   Weissmann, Norbert ^b   Seeger, Werner ^b   Gessler, Tobias ^b   Kissel, Thomas ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

Gene delivery; Low molecular weight PEI; Membrane interaction; PEI copolymers; Pulmonary application in mice; Surface activity

Indexed keywords

COPOLYMER; DNA; ISOTONIC SOLUTION; MACROGOL; POLYETHYLENEIMINE DERIVATIVE; PROPYLENE GLYCOL;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CRITICAL MICELLE CONCENTRATION; CYTOTOXICITY; DNA BINDING; ENDOSOME; GENE DELIVERY SYSTEM; GENETIC TRANSFECTION; HEMOLYSIS; IN VITRO STUDY; IN VIVO STUDY; LUNG; MOUSE; NONHUMAN; PRIORITY JOURNAL; SYNTHESIS;

ANIMALS; CELL LINE; CELL MEMBRANE; DNA; ERYTHROCYTES; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; IMINES; LUNG; MICE; MICE, INBRED C57BL; MICELLES; PLASMIDS; POLYETHYLENES; SURFACE-ACTIVE AGENTS; TRANSFECTION;

MAMMALIA; MUS;

EID: 79952637995     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.1538     Document Type: Article

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