Programmed death 1 mRNA in peripheral blood as biomarker of acute renal allograft rejection

Chinese Medical Journal

Volumn 124, Issue 5, 2011, Pages 674-678

  Wang, Ya Wen ^a   Wang, Zhen ^a   Shi, Bing Yi ^b  

^a General Hospital of Chinese People's Liberation Army   (China)

^b 309TH HOSPITAL OF PLA   (China)

Author keywords

Acute rejection; Biomarker; Kidney transplantation; Programmed death 1

Indexed keywords

CREATININE; MESSENGER RNA; PROGRAMMED DEATH 1 RECEPTOR;

ADULT; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DELAYED GRAFT FUNCTION; DISEASE SEVERITY; FEMALE; GRAFT FAILURE; HUMAN; HUMAN CELL; KIDNEY ALLOGRAFT REJECTION; KIDNEY BIOPSY; KIDNEY TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; NON INVASIVE PROCEDURE; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADULT; ANTIGENS, CD; APOPTOSIS REGULATORY PROTEINS; BIOLOGICAL MARKERS; DELAYED GRAFT FUNCTION; FEMALE; GRAFT REJECTION; HUMANS; LEUKOCYTES, MONONUCLEAR; MALE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; YOUNG ADULT;

EID: 79952545441     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.2011.05.007     Document Type: Article

References (34)

1. El-Zoghby ZM, Stegall MD, Lager DJ, Kremers WK, Amer H, Gloor JM, et al. Identifying specific causes of kidney allograft loss. Am J Transplant 2009; 9: 527-535.
2. Beckingham IJ, Nicholson ML, Bell PR. Analysis of factors associated with complications following renal transplant needle core biopsy. Br J Urol 1994; 73: 13-15.
3. Opelz G. Critical evaluation of the association of acute with chronic graft rejection in kidney and heart transplant recipients: the Collaborative Transplant Study. Transplant Proc 1997; 29: 73-76.
4. Mazariegos GV, Zahorchak AF, Reyes J, Ostrowski L, Flynn B, Zeevi A, et al. Dendritic cell subset ratio in peripheral blood correlates with successful withdrawal of immunosuppression in liver transplant patients. Am J Transplant 2003; 3: 689-696.
5. Mazariegos GV, Zahorchak AF, Reyes J, Chapman H, Zeevi A, Thomson AW. Dendritic cell subset ratio in tolerant, weaning and nontolerant liver recipients is not affected by extent of immunosuppression. Am J Transplant 2005; 5: 314-322.
6. Brouard S, Mansfield E, Braud C, Li L, Giral M, Hsieh SC, et al. Identification of a peripheral blood transcriptional biomarker panel associated with operational renal allograft tolerance. Proc Natl Acad Sci U S A 2007; 104: 15448-15453.
7. Martinez-Llordella M, Lozano JJ, Puig-Pey I, Orlando G, Tisone G, Lerut J, et al. Using transcriptional profiling to develop a diagnostic test of operational tolerance in liver transplant recipients. J Clin Invest 2008; 118: 2845-2857.
8. Muthukumar T, Dadhania D, Ding R, Snopkowski C, Naqvi R, Lee JB, et al. Messenger RNA for FOXP3 in the urine of renal-allograft recipients. N Engl J Med 2005; 353: 2342-2351.
9. Chen L. Co-inhibitorymolecules of the B7-CD28 family in the control of T-cell immunity. Nat Rev Immunol 2004; 4: 336-347.
10. Greenwald RJ, Freeman GJ, SharpeAH. The B7 family revisited. Ann Rev Immunol 2005; 23: 515-548.
11. Clarkson MR, Sayegh MH. T-cell costimulatory pathways in allograft rejection and tolerance. Transplantation 2005; 80: 555-563.
12. Keir ME, Butte MJ, Freeman GJ, Sharpe AH. PD-1 and its ligands in tolerance and immunity. Ann Rev Immunol 2008; 26: 677-704.
13. Wang J, Yoshida T, Nakaki F, Hiai H, Okazaki T, Honjo T. Establishment of NOD-Pd-cd1-/- mice as an efficient animalmodel of type I diabetes. Proc Natl Acad Sci U S A 2005; 102: 11823-11828.
14. Keir ME, Liang SC, Guleria I, Latchman YE, Qipo A, Albacker LA, et al. Tissue expression of PD-L1 mediates peripheral T cell tolerance. J Exp Med 2006; 203: 883-895.
15. Barber DL, Wherry EJ, Masopust D, Zhu B, Allison JP, Sharpe AH, et al. Restoring function in exhausted CD8 T cells during chronic viral infection. Nature 2006; 439: 682-687.
16. Day CL, Kaufmann DE, Kiepiela P, Brown JA, Moodley ES, Reddy S, et al. PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature 2006; 443: 350-354.
17. Boni C, Fisicaro P, Valdatta C, Amadei B, Di Vincenzo P, Giuberti T, et al. Characterization of hepatitis B virus (HBV)- specific T-cell dysfunction in chronic HBV infection. J Virol 2007; 81: 4215-4225.
18. Maier H, IsogawaM, Freeman GJ, Chisari FV. PD-1: PD-L1 interactions contribute to the functional supp ression of virus-specific CD8+ T lymphocytes in the liver. J Immunol 2007; 178: 2714-2720.
19. Tejani AH, Sullivan EK, Alexander SR, Fine RN, Harmon WE, Kohaut EC. Predictive factors for delayed graft function (DGF) and its impact on renal graft survival in children: a report of the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS). Pediatr Transplant 1999; 3: 293-300.
20. Krüger B, Krick S, Dhillon N, Lerner SM, Ames S, Bromberg JS, et al. Donor Toll-like receptor 4 contributes to ischemia and reperfusion injury following human kidney transplantation. Proc Natl Acad Sci U S A 2009; 106: 3390-3395.
21. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001; 25: 402-408.
22. Solez K, Colvin RB, Racusen LC, Haas M, Sis B, Mengel M, et al. Banff 07 classification of renal allograft pathology: updates and future directions. Am J Transplant 2008; 8: 753-760.
23. Hori J, WangM, MiyashitaM, Tanemoto K, Takahashi H, Takemori T, et al. B7-H1-induced apoptosis as a mechanism of immune privilege of corneal allografts. J Immunol 2006; 177: 5928-5935.
24. Probst HC, McCoy K, Okazaki T, Honjo T, van den Broek M. Resting dendritic cells induce peripheral CD8+ T cell tolerance through PD-1 and CTLA-4. Nat Immunol 2005; 6: 280-286.
25. Polanczyk MJ, Hopke C, Vandenbark AA, Offner H. Treg suppressive activity involves estrogen-dependent expression of programmed death-1 (PD-1). Int Immunol 2007; 19: 337-343.
26. Kitazawa Y, Fujino M, Wang Q, Kimura H, Azuma M, Kubo M, et al. Involvement of the programmed death1 /programmed death-1 ligand pathway in CD4+CD25+ regulatory T cell activity to suppress alloimmune responses. Transplantation 2007; 83: 774-782.
27. Alakulppi NS, Kyllönen LE, Partanen J, Salmela KT, Laine JT. Diagnosis of acute renal allograft rejection by analyzing whole blood mRNA expression of lymphocyte marker molecules. Transplantation 2007; 83: 791-798.
28. Truong W, Hancock WW, Anderson CC, Merani S, Shapiro AM. Coinhibitory T-cell signaling in islet allograft rejection and tolerance. Cell Transplant 2006; 15: 105-119.
29. Habicht A, Kewalaramani R, Vu MD, Demirci G, Blazar BR, Sayegh MH, et al. Striking dichotomy of PD-L1 and PD-L2 pathways in regulating alloreactive CD4+ and CD8+ T cells in vivo. Am J Transplant 2007; 7: 2683-2692.
30. Lu LF, Lind EF, Gondek DC, Bennett KA, Gleeson MW, Pino-Lagos K, et al. Mast cells are essential inter-mediaries in regulatory T cell tolerance. Nature 2006; 442: 997-1002.
31. Borel JF, Baumann G. Molecular mechanism of immunosuppressive agents. Bull Mem Acad R Med Belg 1994; 149: 97-101.
32. Chemnitz, JM, Parry RV, Nichols KE, June CH, Riley JL. SHP-1 and SHP-2 associate with immunoreceptor tyrosinebased switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation. J Immunol 2004; 173: 945-954.
33. Cao J, Liu FX, Yu MX. Expression of programmed death 1 and its ligands in the liver of autoimmune hepatitis C57BL/6 mice. Chin Med J 2009; 122: 1941-1946.
34. Kirk AD, Mannon RB, Swanson SJ, Hale DA. Strategies for minimizing immunosuppression in kidney transplantation. Transplant Int 2005; 18: 2-14.