-
1
-
-
62249171613
-
Current developments in anti-HIV/AIDS gene therapy
-
Tsygankov, A.Y.: Current developments in anti-HIV/AIDS gene therapy. Curr. Opin. Investig Drugs 10(2), 137-149 (2009)
-
(2009)
Curr. Opin. Investig Drugs
, vol.10
, Issue.2
, pp. 137-149
-
-
Tsygankov, A.Y.1
-
3
-
-
0029967721
-
HIV-1 dynamics in vivo: Virion clearance rate, infected cell life-span, and viral generation time
-
Perelson, A.S., Neumann, A.U., Markowitz, M., Leonard, J., Ho, D.: HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time. Science 271, 1582-1586 (1996) (Pubitemid 26097216)
-
(1996)
Science
, vol.271
, Issue.5255
, pp. 1582-1586
-
-
Perelson, A.S.1
Neumann, A.U.2
Markowitz, M.3
Leonard, J.M.4
Ho, D.D.5
-
4
-
-
62249095476
-
The challenge of finding a cure for HIV infection
-
Richman, D., Margolis, D., Delaney, M., Greene, W.C., Hazuda, D., Pomerantz, R.J.: The challenge of finding a cure for HIV infection. Science 323, 1304-1307 (2009)
-
(2009)
Science
, vol.323
, pp. 1304-1307
-
-
Richman, D.1
Margolis, D.2
Delaney, M.3
Greene, W.C.4
Hazuda, D.5
Pomerantz, R.J.6
-
5
-
-
34447528803
-
Modeling within-host HIV-1 dynamics and the evolution of drug resistance: Trade-offs between viral enzyme function and drug susceptibility
-
DOI 10.1016/j.jtbi.2007.04.014, PII S0022519307001968
-
Rong, L., Gilchrist, M.A., Feng, Z., Perelson, A.S.: Modeling within-host HIV-1 dynamics and the evolution of drug resistance: Trade-offs between viral enzyme function and drug susceptibility. J. Theo. Biol. 247, 804-818 (2007) (Pubitemid 47081052)
-
(2007)
Journal of Theoretical Biology
, vol.247
, Issue.4
, pp. 804-818
-
-
Rong, L.1
Gilchrist, M.A.2
Feng, Z.3
Perelson, A.S.4
-
6
-
-
33846106932
-
Distinguishing HIV-1 drug resistance, accessory, and viral fitness mutations using conditional selection pressure analysis of treated versus untreated patient samples
-
Chen, L., Lee, C.: Distinguishing HIV-1 drug resistance, accessory, and viral fitness mutations using conditional selection pressure analysis of treated versus untreated patient samples. Biology Direct 1(1), 14 (2006)
-
(2006)
Biology Direct
, vol.1
, Issue.1
, pp. 14
-
-
Chen, L.1
Lee, C.2
-
7
-
-
34250380707
-
HIV-1 protease substrate binding and product release pathways explored with coarse-grained molecular dynamics
-
DOI 10.1529/biophysj.106.100560
-
Trylska, J., Tozzini, V., Chang, C., McCammon, J.A.: HIV-1 protease substrate binding and product release pathways explored with coarse-grained molecular dynamics. Biophys. J. 92, 4179-4187 (2007) (Pubitemid 46910534)
-
(2007)
Biophysical Journal
, vol.92
, Issue.12
, pp. 4179-4187
-
-
Trylska, J.1
Tozzini, V.2
Chang, C.-E.A.3
McCammon, J.A.4
-
8
-
-
33846247964
-
Computing the amino acid specificity of fluctuations in biomolecular systems
-
Hamacher, K., McCammon, J.A.: Computing the amino acid specificity of fluctuations in biomolecular systems. J. Chem. Theory Comput. 2(3), 873-878 (2006)
-
(2006)
J. Chem. Theory Comput
, vol.2
, Issue.3
, pp. 873-878
-
-
Hamacher, K.1
McCammon, J.A.2
-
9
-
-
49049087284
-
Relating sequence evolution of HIV1-protease to its underlying molecular mechanics
-
Hamacher, K.: Relating sequence evolution of HIV1-protease to its underlying molecular mechanics. Gene 422, 30-36 (2008)
-
(2008)
Gene
, vol.422
, pp. 30-36
-
-
Hamacher, K.1
-
10
-
-
33846054821
-
The HIV positive selection mutation database
-
DOI 10.1093/nar/gkl855
-
Pan, C., Kim, J., Chen, L., Wang, Q., Lee, C.: The hiv positive selection mutation database. Nuc. Acids Res. 35(1), D371-D375 (2007) (Pubitemid 46056234)
-
(2007)
Nucleic Acids Research
, vol.35
, Issue.SUPPL. 1
-
-
Pan, C.1
Kim, J.2
Chen, L.3
Wang, Q.4
Lee, C.5
-
11
-
-
1842509978
-
Positive Selection Detection in 40,000 Human Immunodeficiency Virus (HIV) Type 1 Sequences Automatically Identifies Drug Resistance and Positive Fitness Mutations in HIV Protease and Reverse Transcriptase
-
DOI 10.1128/JVI.78.7.3722-3732.2004
-
Chen, L., Perlina, A., Lee, C.J.: Positive Selection Detection in 40,000 Human Immunodeficiency Virus (HIV) Type 1 Sequences Automatically Identifies Drug Resistance and Positive Fitness Mutations in HIV Protease and Reverse Transcriptase. J. Virol. 78(7), 3722-3732 (2004) (Pubitemid 38568311)
-
(2004)
Journal of Virology
, vol.78
, Issue.7
, pp. 3722-3732
-
-
Chen, L.1
Perlina, A.2
Lee, C.J.3
-
12
-
-
84944486544
-
Prediction and entropy of printed english
-
Shannon, C.E.: Prediction and entropy of printed english. The Bell System Technical Journal 30, 50-64 (1951)
-
(1951)
The Bell System Technical Journal
, vol.30
, pp. 50-64
-
-
Shannon, C.E.1
-
13
-
-
33646413711
-
Immunological bioinformatics
-
MIT Press
-
Lund, O., Nielsen,M., Lundegaard, C., Brunak, C.K.S.: Immunological Bioinformatics. MIT Press, Cambridge (2005)
-
(2005)
Cambridge
-
-
Lund Nielsen O, M.1
Lundegaard, C.2
Brunak, C.K.S.3
-
14
-
-
35948976625
-
Information theoretical measures to analyze trajectories in rational molecular design
-
DOI 10.1002/jcc.20759
-
Hamacher, K.: Information theoretical measures to analyze trajectories in rational molecular design. J. Comp. Chem. 28(16), 2576-2580 (2007) (Pubitemid 350074133)
-
(2007)
Journal of Computational Chemistry
, vol.28
, Issue.16
, pp. 2576-2580
-
-
Hamacher, K.1
-
15
-
-
77956354009
-
Protein domain phylogenies - Information theory and evolutionary dynamics
-
Fred, A., Filipe, J., Gamboa, H. (eds.)
-
Hamacher, K.: Protein domain phylogenies - information theory and evolutionary dynamics. In: Fred, A., Filipe, J., Gamboa, H. (eds.) BIOINFORMATICS 2010, pp. 114-122 (2010)
-
(2010)
BIOINFORMATICS 2010
, pp. 114-122
-
-
Hamacher, K.1
-
16
-
-
77955800065
-
Distance-dependent classification of amino acids by information theory
-
Pape, S., Hoffgaard, F., Hamacher, K.: Distance-dependent classification of amino acids by information theory. Proteins: Structure, Function, and Bioinformatics 78, 2322-2328 (2010)
-
(2010)
Proteins: Structure, Function, and Bioinformatics
, vol.78
, pp. 2322-2328
-
-
Pape, S.1
Hoffgaard, F.2
Hamacher, K.3
-
17
-
-
77952957266
-
Co-evolution in HIV enzymes
-
Fred, A., Filipe, J., Gamboa, H. (eds.)
-
Boba, P., Weil, P., Hoffgaard, F., Hamacher, K.: Co-evolution in HIV enzymes. In: Fred, A., Filipe, J., Gamboa, H. (eds.) BIOINFORMATICS 2010, pp. 39-47 (2010)
-
(2010)
BIOINFORMATICS 2010
, pp. 39-47
-
-
Boba, P.1
Weil, P.2
Hoffgaard, F.3
Hamacher, K.4
-
18
-
-
70449726432
-
Estimating sufficient statistics in co-evolutionary analysis by mutual information
-
Weil, P., Hoffgaard, F., Hamacher, K.: Estimating sufficient statistics in co-evolutionary analysis by mutual information. Computational Biology and Chemistry 33(6), 440-444 (2009)
-
(2009)
Computational Biology and Chemistry
, vol.33
, Issue.6
, pp. 440-444
-
-
Weil, P.1
Hoffgaard, F.2
Hamacher, K.3
-
19
-
-
79952531542
-
-
Boba, P., Hamacher, K. (2009), http://bioserver.bio.tu-darmstadt.de/HIV
-
(2009)
-
-
Boba, P.1
Hamacher, K.2
-
21
-
-
9944232661
-
Taking aim at a moving target: Designing drugs to inhibit drug-resistant HIV-1 reverse transcriptases
-
DOI 10.1016/j.sbi.2004.10.013, PII S0959440X04001897
-
Sarafianos, S.G., Das, K., Hughes, S.H., Arnold, E.: Taking aim at a moving target: designing drugs to inhibit drug-resistant hiv-1 reverse transcriptases. Current Opinion in Structural Biology 14(6), 716-730 (2004) (Pubitemid 39592583)
-
(2004)
Current Opinion in Structural Biology
, vol.14
, Issue.6
, pp. 716-730
-
-
Sarafianos, S.G.1
Das, K.2
Hughes, S.H.3
Arnold, E.4
-
22
-
-
68149096920
-
The search for potent, small molecule nnrtis: A review
-
Prajapati, D.G., Ramajayam, R., Yadav, M.R., Giridhar, R.: The search for potent, small molecule nnrtis: A review. Bioorganic & Medicinal Chemistry 17(16), 5744-5762 (2009)
-
(2009)
Bioorganic & Medicinal Chemistry
, vol.17
, Issue.16
, pp. 5744-5762
-
-
Prajapati, D.G.1
Ramajayam, R.2
Yadav, M.R.3
Giridhar, R.4
-
23
-
-
13044254785
-
JE-2147: A dipeptide protease inhibitor (PI) that potently inhibits multi-PI-resistant HIV-1
-
DOI 10.1073/pnas.96.15.8675
-
Yoshimura, K., Kato, R., Yusa, K., Kavlick, M.F., Maroun, V., Nguyen, A., Mimoto, T., Ueno, T., Shintani, M., Falloon, J., Masur, H., Hayashi, H., Erickson, J., Mitsuya, H.: JE- 2147: A dipeptide protease inhibitor (PI) that potently inhibits multi-PI-resistantHIV-1. Proc. Natl. Acad. Sci. 96, 8675-8680 (1999) (Pubitemid 29354850)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.15
, pp. 8675-8680
-
-
Yoshimura, K.1
Kato, R.2
Yusa, K.3
Kavlick, M.F.4
Maroun, V.5
Nguyen, A.6
Mimoto, T.7
Ueno, T.8
Shintani, M.9
Falloon, J.10
Masur, H.11
Hayashi, H.12
Erickson, J.13
Mitsuya, H.14
-
24
-
-
0037046143
-
Anisotropic dynamics of the JE- 2147-HIV protease complex: Drug resistance and thermodynamic binding mode examined in a 1.09 a structure
-
Reiling, K., Endres, N., Dauber, D., Craik, C., Stroud, R.: Anisotropic dynamics of the JE- 2147-HIV protease complex: Drug resistance and thermodynamic binding mode examined in a 1.09 a structure. Biochemistry 41, 4582 (2002)
-
(2002)
Biochemistry
, vol.41
, pp. 4582
-
-
Reiling, K.1
Endres, N.2
Dauber, D.3
Craik, C.4
Stroud, R.5
-
25
-
-
33744491862
-
Restrained molecular dynamics simulations of HIV-1 protease: The first step in validating a new target for drug design
-
DOI 10.1002/bip.20497
-
Perryman, A.L., Lin, J.H., McCammon, J.A.: Restrained molecular dynamics simulations of hiv-1 protease: The first step in validating a new target for drug design. Biopolymers 82(3), 272-284 (2006) (Pubitemid 43798156)
-
(2006)
Biopolymers
, vol.82
, Issue.3
, pp. 272-284
-
-
Perryman, A.L.1
Lin, J.-H.2
McCammon, J.A.3
-
27
-
-
0029878720
-
VMD - Visual Molecular Dynamics
-
Humphrey, W., Dalke, A., Schulten, K.: VMD - Visual Molecular Dynamics. Journal of Molecular Graphics 14, 33-38 (1996)
-
(1996)
Journal of Molecular Graphics
, vol.14
, pp. 33-38
-
-
Humphrey, W.1
Dalke, A.2
Schulten, K.3
|