Positive Selection Detection in 40,000 Human Immunodeficiency Virus (HIV) Type 1 Sequences Automatically Identifies Drug Resistance and Positive Fitness Mutations in HIV Protease and Reverse Transcriptase

Journal of Virology

Volumn 78, Issue 7, 2004, Pages 3722-3732

  Chen, Lamei ^a   Perlina, Alla ^b   Lee, Christopher J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Specialty Laboratories   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; PROTEINASE; RNA DIRECTED DNA POLYMERASE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; AMINO ACID SEQUENCE; ARTICLE; DRUG DESIGN; DRUG RESISTANCE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; SEQUENCE ANALYSIS; TREATMENT PLANNING; VIRUS MUTATION; VIRUS REPLICATION; ANTIBIOTIC RESISTANCE; AUTOMATION; DRUG EFFECT; ENZYMOLOGY; GENETIC DATABASE; GENETIC LINKAGE; GENETIC SELECTION; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; METABOLISM; MISSENSE MUTATION; NUCLEOTIDE SEQUENCE; PHENOTYPE; STRUCTURE ACTIVITY RELATION; VIROLOGY;

AMINO ACID SEQUENCE; ANTI-HIV AGENTS; AUTOMATION; BASE SEQUENCE; DATABASES, GENETIC; DNA MUTATIONAL ANALYSIS; DRUG RESISTANCE, VIRAL; HIV INFECTIONS; HIV PROTEASE; HIV-1; HIV-1 REVERSE TRANSCRIPTASE; HUMANS; LOD SCORE; MUTATION, MISSENSE; PHENOTYPE; SELECTION (GENETICS); STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 1842509978     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.78.7.3722-3732.2004     Document Type: Article

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