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Volumn 41, Issue 14, 2002, Pages 4582-4594

Anisotropic dynamics of the JE-2147-HIV protease complex: Drug resistance and thermodynamic binding mode examined in a 1.09 Å structure

(5) Reiling, K Kinkead a Endres, Nicholas F a Dauber, Deborah S a Craik, Charles S a Stroud, Robert M a

a UNIVERSITY OF CALIFORNIA (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG RESISTANCE;

ANISOTROPY; ENZYME INHIBITION; ENZYMES; MOLECULAR STRUCTURE; THERMODYNAMIC PROPERTIES;

BIOCHEMISTRY;

INDINAVIR; JE 2147; KYNOSTATIN 272; NELFINAVIR; PROTEINASE; PROTEINASE INHIBITOR; RITONAVIR; SAQUINAVIR; UNCLASSIFIED DRUG; VIRUS ENZYME;

ANISOTROPY; ARTICLE; COMPLEX FORMATION; DRUG PROTEIN BINDING; DYNAMICS; ENTHALPY; ENTROPY; ENZYME ANALYSIS; ENZYME BINDING; ENZYME STRUCTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; STRUCTURE ANALYSIS; THERMODYNAMICS;

AMINO ACID SEQUENCE; ANISOTROPY; ASPARTIC ACID; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; DIPEPTIDES; HIV PROTEASE; HIV PROTEASE INHIBITORS; KINETICS; MODELS, MOLECULAR; PHENYLBUTYRATES; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; THERMODYNAMICS;

RNA VIRUSES;

EID: 0037046143 PISSN: 00062960 EISSN: None Source Type: Journal
DOI: 10.1021/bi011781z Document Type: Article

Times cited : (56)

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