Accurate quantification of functional analogy among close homologs

PLoS Computational Biology

Volumn 7, Issue 2, 2011, Pages

  Chikina, Maria D ^a   Troyanskaya, Olga G ^a,b  

^a PRINCETON UNIVERSITY   (United States)

^b Princeton University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE EXPRESSION; MOLECULAR BIOLOGY;

ACCURATE QUANTIFICATIONS; ANIMAL MODEL; BIOLOGICAL PROCESS; EXPERIMENTAL KNOWLEDGE; FUNCTIONAL SIMILARITY; HOMOLOGOUS PROTEINS; HUMAN DISEASE; SEQUENCE COMPARISONS; SEQUENCE SIMILARITY; SIMILARITY MEASURE;

PROTEINS;

LAMIN; SNAP25 PROTEIN; SNARE PROTEIN; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; SYNAPTOSOMAL ASSOCIATED PROTEIN 25;

AMINO ACID SEQUENCE; ARTICLE; BAYES THEOREM; CONTROLLED STUDY; CONVERGENT EVOLUTION; CYTOSOL; GENE EXPRESSION; GENE MUTATION; MOLECULAR BIOLOGY; PREDICTION; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; ANIMAL; BIOLOGY; CHEMISTRY; DNA MICROARRAY; EVALUATION; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORK; GENETICS; HUMAN; MOLECULAR EVOLUTION; PHYSIOLOGY; SPECIES DIFFERENCE; STATISTICS; STRUCTURAL HOMOLOGY;

ANIMALIA;

ANIMALS; BAYES THEOREM; COMPUTATIONAL BIOLOGY; EVOLUTION, MOLECULAR; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORKS; HUMANS; LAMINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SPECIES SPECIFICITY; STRUCTURAL HOMOLOGY, PROTEIN; SUPEROXIDE DISMUTASE; SYNAPTOSOMAL-ASSOCIATED PROTEIN 25;

EID: 79952481894     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1001074     Document Type: Article

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