메뉴 건너뛰기




Volumn 8, Issue 3, 2011, Pages 133-140

Vaccinating against Helicobacter pylori infection

Author keywords

[No Author keywords available]

Indexed keywords

CHOLERA VACCINE; ESCHERICHIA COLI VACCINE; HELICOBACTER PYLORI VACCINE; PLACEBO; UREASE;

EID: 79952454960     PISSN: 17595045     EISSN: 17595053     Source Type: Journal    
DOI: 10.1038/nrgastro.2011.1     Document Type: Review
Times cited : (93)

References (75)
  • 1
    • 0027176157 scopus 로고
    • An international association between Helicobacter pylori infection and gastric cancer
    • Eurogast Study Group
    • Eurogast Study Group. An international association between Helicobacter pylori infection and gastric cancer. Lancet 341, 1359-1362 (1993).
    • (1993) Lancet , vol.341 , pp. 1359-1362
  • 2
    • 0028766786 scopus 로고
    • Helicobacter pylori in peptic ulcer disease
    • NIH Consensus Conference
    • NIH Consensus Conference. Helicobacter pylori in peptic ulcer disease. J. Am. Med. Assn. 272, 65-69 (1994).
    • (1994) J. Am. Med. Assn. , vol.272 , pp. 65-69
  • 3
    • 0025945933 scopus 로고
    • Helicobcter pylori infection and the risk of gastric carcinoma
    • Parsonnet, J. et al. Helicobcter pylori infection and the risk of gastric carcinoma. N. Engl. J. Med. 325, 1127-1131 (1991).
    • (1991) N. Engl. J. Med. , vol.325 , pp. 1127-1131
    • Parsonnet, J.1
  • 4
    • 84920247287 scopus 로고
    • Unidentified curved bacilli on gastric epithelium in active chronic gastritis
    • Warren, J. R. & Marshall, B. J. Unidentified curved bacilli on gastric epithelium in active chronic gastritis. Lancet 1, 1273-1275 (1983)
    • (1983) Lancet , vol.1 , pp. 1273-1275
    • Warren, J.R.1    Marshall, B.J.2
  • 7
    • 0025897596 scopus 로고
    • Epidemiology of Helicobacter pylori in an asymptomatic population in the United States. Effect of age, race, and socioeconomic status
    • Graham, D. Y et al. Epidemiology of Helicobacter pylori in an asymptomatic population in the United States. Effect of age, race, and socioeconomic status. Gastroenterology 100, 1495-1501 (1991).
    • (1991) Gastroenterology , vol.100 , pp. 1495-1501
    • Graham, D.Y.1
  • 8
    • 17544368511 scopus 로고    scopus 로고
    • Seroprevalence of six infectious diseases among adults in the United States by race/ethnicity: Data from the third national health and nutrition examination survey
    • Kruszon-Moran, D. & McQuillan, G. M. Seroprevalence of six infectious diseases among adults in the United States by race/ethnicity: data from the third national health and nutrition examination survey. Adv. Data 352, 1-9 (2005).
    • (2005) Adv. Data , vol.352 , pp. 1-9
    • Kruszon-Moran, D.1    McQuillan, G.M.2
  • 9
    • 77949350508 scopus 로고    scopus 로고
    • Y Considering global vaccination against Helicobacter pylori
    • Luther, J. & Kao, J. Y Considering global vaccination against Helicobacter pylori. South. Med. J. 103, 185-186 (2010).
    • (2010) South. Med. J. , vol.103 , pp. 185-186
    • Luther, J.1    Kao, J.2
  • 10
    • 0038579390 scopus 로고    scopus 로고
    • Helicobacter pylori in the developing world
    • Frenck, R. W. Jr & Clemens, J. Helicobacter pylori in the developing world. Microbes Infect. 8, 705-713 (2003).
    • (2003) Microbes Infect. , vol.8 , pp. 705-713
    • Frenck Jr., R.W.1    Clemens, J.2
  • 11
    • 2142712568 scopus 로고    scopus 로고
    • What is the Helicobacter pylori global reinfection rate? Can
    • Parsonnet, J. What is the Helicobacter pylori global reinfection rate? Can. J. Gastroenterol. 17 (Suppl. B), 46-48 (2003).
    • (2003) J. Gastroenterol. , vol.17 , Issue.SUPPL. B , pp. 46-48
    • Parsonnet, J.1
  • 12
    • 27744472492 scopus 로고    scopus 로고
    • The recurrence of Helicobacter pylori infection: Incidence and variables influencing it A critical review
    • Gisbert, J. The recurrence of Helicobacter pylori infection: incidence and variables influencing it A critical review. Am. J. Gastroenterol. 100, 2083-2099 (2005).
    • (2005) Am. J. Gastroenterol. , vol.100 , pp. 2083-2099
    • Gisbert, J.1
  • 13
    • 0035852299 scopus 로고    scopus 로고
    • Quantifying the population impact of a prophylactic Helicobacter pylori vaccine
    • DOI 10.1016/S0264-410X(01)00401-7, PII S0264410X01004017
    • Rupnow, M. F., Shachter, R. D., Owens, D. K. & Parsonnet, J. Quantifying the population impact of a prophylactic Helicobacter pylori vaccine. Vaccine 20, 879-885 (2001). (Pubitemid 34015829)
    • (2001) Vaccine , vol.20 , Issue.5-6 , pp. 879-885
    • Rupnow, M.F.T.1    Shachter, R.D.2    Owens, D.K.3    Parsonnet, J.4
  • 14
    • 34250378240 scopus 로고    scopus 로고
    • Progress in vaccine development against Helicobacter pylori
    • DOI 10.1111/j.1574-695X.2007.00237.x
    • Svennerholm, A. M. & Lundgren, A. Progress in vaccine development against Helicobacter pylori. FEMS Immunol. Med. Microbiol. 50, 146-156 (2007). (Pubitemid 46918647)
    • (2007) FEMS Immunology and Medical Microbiology , vol.50 , Issue.2 , pp. 146-156
    • Svennerholm, A.-M.1    Lundgren, A.2
  • 15
    • 0021259505 scopus 로고
    • Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration
    • Marshall, B. J. & Warren, J. R. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet 1, 1311-1315 (1984).
    • (1984) Lancet , vol.1 , pp. 1311-1315
    • Marshall, B.J.1    Warren, J.R.2
  • 16
    • 0025151949 scopus 로고
    • A small animal model of human Helicobacter pylori active chronic gastritis
    • Lee, A., Fox, J. G., Otto, G. & Murphy, J. A smal animal model of human Helicobacter pylori active chronic gastritis. Gastroenterology 99, 1315-1323 (1990). (Pubitemid 20381865)
    • (1990) Gastroenterology , vol.99 , Issue.5 , pp. 1315-1323
    • Lee, A.1    Fox, J.G.2    Otto, G.3    Murphy, J.4
  • 18
    • 84890131571 scopus 로고    scopus 로고
    • eds Sutton, P & Mitchell, H. CABI, Wallingford
    • st edn Ch. 9 (eds Sutton, P & Mitchell, H.) 167-190 (CABI, Wallingford, 2010).
    • (2010) st Edn Ch. 9 , pp. 167-190
    • Blanchard, T.G.1    Nedrud, J.G.2
  • 19
    • 0029079502 scopus 로고
    • Oral immunization with Helicobacter pylori urease B subunit as a treatment against Helicobacter infection in mice
    • Corthesy-Theulaz, I. et al. Oral immunization with Helicobacter pylori urease B subunit as a treatment against Helicobacter infection in mice. Gastroenterology 109, 115-121 (1995).
    • (1995) Gastroenterology , vol.109 , pp. 115-121
    • Corthesy-Theulaz, I.1
  • 20
    • 0028205426 scopus 로고
    • Therapeutic immunisation against helicobacter infection [4]
    • Doidge, C et al. Therapeutic immunisation against Helicobacter infection. Lancet 343, 914-915 (1994). (Pubitemid 24113641)
    • (1994) Lancet , vol.343 , Issue.8902 , pp. 914-915
    • Doidge, C.1    Gust, I.2    Lee, A.3    Buck, F.4    Hazell, S.5    Manne, U.6
  • 21
    • 0033953585 scopus 로고    scopus 로고
    • Therapeutic immunization against Helicobacter pylori infection in the absence of antibodies
    • DOI 10.1046/j.1440-1711.2000.00881.x
    • Sutton, P et al. Therapeutic immunization against Helicobacter pylori infection in the absence of antibodies. Immunol. Cell. Biol. 78, 28-30 (2000). (Pubitemid 30090986)
    • (2000) Immunology and Cell Biology , vol.78 , Issue.1 , pp. 28-30
    • Sutton, P.1    Wilson, J.2    Kosaka, T.3    Wolowczuk, I.4    Lee, A.5
  • 22
    • 0027653244 scopus 로고
    • Immunisation against gastric infection with Helicobacter species: First step in the prophylaxis of gastric cancer?
    • Chen, M. et al. Immunisation against gastric infection with Helicobacter species: first step in the prophylaxis of gastric cancer? Zentralbl. Bakteriol. 280, 155-165 (1993).
    • (1993) Zentralbl Bakteriol. , vol.280 , pp. 155-165
    • Chen, M.1
  • 23
    • 0027265078 scopus 로고
    • Protection of germ-free mice from infection by Helicobacter felis after active oral or passive IgA immunization
    • DOI 10.1016/0264-410X(93)90309-L
    • Czinn, S. J., Cai, A. & Nedrud, J. G. Protection of germ-free mice from infection by Helicobacter felis after active oral or passive IgA mmunization. Vaccine 11, 637-642 (1993). (Pubitemid 23142620)
    • (1993) Vaccine , vol.11 , Issue.6 , pp. 637-642
    • Czinn, S.J.1    Cai, A.2    Nedrud, J.G.3
  • 25
    • 0029069313 scopus 로고
    • Oral Immunization with recombinant Helicobacter pylori urease induces secretory IgA antibodies and protects mice from challenge with Helicobacter felis
    • Lee, C K. et al. Oral Immunization with recombinant Helicobacter pylori urease induces secretory IgA antibodies and protects mice from challenge with Helicobacter felis. J. Infect. Dis. 172, 161-172 (1995).
    • (1995) J. Infect. Dis. , vol.172 , pp. 161-172
    • Lee, C.K.1
  • 26
    • 0028902758 scopus 로고
    • Development of a mouse model of Helicobacter pylori infection that mimics human disease
    • Marchetti, M. et al. Development of a mouse model of Helicobacter pylori infection that mimics human disease. Science 267, 1655-1658 (1995).
    • (1995) Science , vol.267 , pp. 1655-1658
    • Marchetti, M.1
  • 27
    • 0028068834 scopus 로고
    • Immunization of BALB/c mice against Helicobacter felis infection with Helicobacter pylori urease
    • Michetti, P et al. Immunization of BALB/c mice against Helicobacter felis infection with Helicobacter pylori urease. Gastroenterology 107, 1002-1011 (1994).
    • (1994) Gastroenterology , vol.107 , pp. 1002-1011
    • Michetti, P.1
  • 28
    • 0030965889 scopus 로고    scopus 로고
    • Novel intranasal immunization techniques for antibody induction and protection of mice against gastric Helicobacter felis infection
    • DOI 10.1016/S0264-410X(97)00203-X, PII S0264410X97002034
    • Weltzin, R. et al. Novel intranasal immunization techniques for antibody induction and protection of mice against gastric Helicobacter felis infection. Vaccine 15, 370-376 (1997). (Pubitemid 27157692)
    • (1997) Vaccine , vol.15 , Issue.4 , pp. 370-376
    • Weltzin, R.1    Kleanthous, H.2    Guirakhoo, F.3    Monath, T.P.4    Lee, C.K.5
  • 31
    • 0032078331 scopus 로고    scopus 로고
    • Systemic immunization with urease protects mice against Helicobacter pylori infection
    • DOI 10.1016/S0264-410X(97)00258-2, PII S0264410X97002582
    • Guy, B. et al. Systemic immunization with urease protects mice against Helicobacter pylori infection. Vaccine 16, 850-856 (1998). (Pubitemid 28238673)
    • (1998) Vaccine , vol.16 , Issue.8 , pp. 850-856
    • Guy, B.1    Hessler, C.2    Fourage, S.3    Haensler, J.4    Vialon-Lafay, E.5    Rokbi, B.6    Millet, M.-J.Q.7
  • 32
    • 59849109226 scopus 로고    scopus 로고
    • Vaccination of mice against H. pylori induces a strong Th-17 response and immunity that is neutrophil dependent
    • Delyria, E. S., Redline, R. W. & Blanchard, T. G. vaccination of mice against H. pylori induces a strong Th-17 response and immunity that is neutrophil dependent. Gastroenterology 136, 247-256 (2008).
    • (2008) Gastroenterology , vol.136 , pp. 247-256
    • Delyria, E.S.1    Redline, R.W.2    Blanchard, T.G.3
  • 33
    • 66149155792 scopus 로고    scopus 로고
    • Interleukin-17 is a critical mediator of vaccine-induced reduction of Helicobacter infection in the mouse model
    • Velin, D. et al. Interleukin-17 is a critical mediator of vaccine-induced reduction of Helicobacter infection in the mouse model. Gastroenterology 136, 2237-2246 (2009).
    • (2009) Gastroenterology , vol.136 , pp. 2237-2246
    • Velin, D.1
  • 34
    • 0035877051 scopus 로고    scopus 로고
    • The role of T cell subsets and cytokines in the pathogenesis of Helicobacter pylori gastritis in mice
    • Eaton, K. A., Mefford, M. & Thevenot, T. The role of T cell subsets and cytokines in the pathogenesis of Helicobacter pylori gastritis in mice. J. Immunol. 166, 7456-7461 (2001). (Pubitemid 32525623)
    • (2001) Journal of Immunology , vol.166 , Issue.12 , pp. 7456-7461
    • Eaton, K.A.1    Mefford, M.2    Thevenot, T.3
  • 35
    • 22344452214 scopus 로고    scopus 로고
    • Mast cells are critical mediators of vaccine-induced Helicobacter clearance in the mouse model
    • DOI 10.1053/j.gastro.2005.04.010, PII S001650850500692X
    • Velin, D., Bachmann, D., Bouzourene, H. & Michetti, P Mast cells are critical mediators of vaccine-induced Helicobacter clearance in the mouse model. Gastroenterology 129, 142-155 (2005). (Pubitemid 41002051)
    • (2005) Gastroenterology , vol.129 , Issue.1 , pp. 142-155
    • Velin, D.1    Bachmann, D.2    Bouzourene, H.3    Michetti, P.4
  • 42
    • 0033529607 scopus 로고    scopus 로고
    • Immunization of rhesus monkeys with a mucosal prime, parenteral boost strategy protects against infection with Helicobacter pylori
    • DOI 10.1016/S0264-410X(99)00144-9, PII S0264410X99001449
    • Lee, C. K. et al. Immunization of rhesus monkeys with a mucosal prime, parenteral boost strategy protects against infection with Helicobacter pylori. Vaccine 17, 3072-3082 (1999). (Pubitemid 29366987)
    • (1999) Vaccine , vol.17 , Issue.23-24 , pp. 3072-3082
    • Lee, C.K.1    Soike, K.2    Giannasca, P.3    Hill, J.4    Weltzin, R.5    Kleanthous, H.6    Blanchard, J.7    Monath, T.P.8
  • 43
    • 0031754639 scopus 로고    scopus 로고
    • Vaccination of gnotobiotic piglets against Helicobacter pylori
    • Eaton, K. A., Ringler, S. S. & Krakowka, S. vaccination of gnotobiotic piglets against Helicobacter pylori. J. Infect Dis. 178, 1399-1405 (1998).
    • (1998) J. Infect Dis. , vol.178 , pp. 1399-1405
    • Eaton, K.A.1    Ringler, S.S.2    Krakowka, S.3
  • 45
    • 0036839343 scopus 로고    scopus 로고
    • Safety and efficacy of low dose Escherichia coli enterotoxin adjuvant for urease based oral immunisation against Helicobacter pylori in healthy volunteers
    • DOI 10.1136/gut.51.5.634
    • Banerjee, S. et al. Safety and efficacy of low dose Escherichia coli enterotoxin adjuvant for urease based oral immunisation against Helicobacter pylori in healthy volunteers. Gut 51, 634-640 (2002). (Pubitemid 35216848)
    • (2002) Gut , vol.51 , Issue.5 , pp. 634-640
    • Banerjee, S.1    Medina-Fatimi, A.2    Nichols, R.3    Tendler, D.4    Michetti, M.5    Simon, J.6    Kelly, C.P.7    Monath, T.P.8    Michetti, P.9
  • 48
    • 74149085715 scopus 로고    scopus 로고
    • Toward the development of a stable, freeze-dried formulation of Helicobacter pylori killed whole cell vaccine adjuvanted with a novel mutant of Escherichia coli heat-labile toxin
    • Summerton, N. A. et al. Toward the development of a stable, freeze-dried formulation of Helicobacter pylori killed whole cell vaccine adjuvanted with a novel mutant of Escherichia coli heat-labile toxin. Vaccine 28, 1404-1411 (2010).
    • (2010) Vaccine , vol.28 , pp. 1404-1411
    • Summerton, N.A.1
  • 49
    • 0035010023 scopus 로고    scopus 로고
    • Safety and immunogenicity of oral inactivated whole-cell Helicobacter pylori vaccine with adjuvant among volunteers with or without subclinical infection
    • DOI 10.1128/IAI.69.6.3581-3590.2001
    • Kotloff, K. L. et al. Safety and immunogenicity of oral inactivated whole-cell Helicobacter pylori vaccine with adjuvant among volunteers with or without subclinical infection. Infect Immun. 69, 3581-3590 (2001). (Pubitemid 32493271)
    • (2001) Infection and Immunity , vol.69 , Issue.6 , pp. 3581-3590
    • Kotloff, K.L.1    Sztein, M.B.2    Wasserman, S.S.3    Losonsky, G.A.4    DiLorenzo, S.C.5    Walker, R.I.6
  • 50
    • 0029056004 scopus 로고
    • The GroES homolog of Helicobacter pylori confers protective immunity against mucosal infection in mice
    • Ferrero, R. L. et al. The GroES homolog of Helicobacter pylori confers protective immunity against mucosal infection in mice. Proc. Natl Acad. Sci. USA 92, 6499-6503 (1995).
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 6499-6503
    • Ferrero, R.L.1
  • 51
    • 0034116071 scopus 로고    scopus 로고
    • Pilot study of phoP/phoQ-deleted Salmonella enterica serovar typhimurium expressing Helicobacter priori urease in adult volunteers
    • DOI 10.1128/IAI.68.4.2135-2141.2000
    • Angelakopoulos, H. & Hohmann, E. L. Pilot study of phoP/phoQ-deleted Salmonella enterica serovar typhimurium expressing Helicobacter pylori urease in adult volunteers. Infect. Immun. 68, 2135-2141 (2000). (Pubitemid 30164846)
    • (2000) Infection and Immunity , vol.68 , Issue.4 , pp. 2135-2141
    • Angelakopoulos, H.1    Hohmann, E.L.2
  • 52
    • 0032873474 scopus 로고    scopus 로고
    • Safety and immunogenicity of phoP/phoQ-deleted Salmonella typhi expressing Helicobacter pylori urease in adult volunteers
    • DOI 10.1016/S0264-410X(99)00246-7, PII S0264410X99002467
    • DiPetrillo, M. D. et al. Safety and immunogenicity of phoP/phoQ-deleted Salmonella typhi expressing Helicobacter pylori urease in adult volunteers. Vaccine 18, 449-459 (1999). (Pubitemid 29462601)
    • (1999) Vaccine , vol.18 , Issue.5-6 , pp. 449-459
    • Dipetrillo, M.D.1    Tibbetts, T.2    Kleanthous, H.3    Killeen, K.P.4    Hohmann, E.L.5
  • 53
    • 0035852273 scopus 로고    scopus 로고
    • Safety and immunogenicity of live recombinant Salmonella enterica serovar Typhi Ty21a expressing urease A and B from Helicobacter pylori in human volunteers
    • DOI 10.1016/S0264-410X(01)00391-7, PII S0264410X01003917
    • Bumann, D. et al. Safety and immunogenicity of live recombinant Salmonella enterica serovar Typhi Ty21a expressing urease A and B from Helicobacter pylori in human volunteers. Vaccine 20, 845-852 (2001). (Pubitemid 34015824)
    • (2001) Vaccine , vol.20 , Issue.5-6 , pp. 845-852
    • Bumann, D.1    Metzger, W.G.2    Mansouri, E.3    Palme, O.4    Wendland, M.5    Hurwitz, R.6    Haas, G.7    Aebischer, T.8    Von Specht, B.-U.9    Meyer, T.F.10
  • 54
    • 2442498417 scopus 로고    scopus 로고
    • Impact of vector-priming on the immunogenicity of a live recombinant Salmonella enterica serovar typhi Ty21a vaccine expressing urease A and B from Helicobacter pylori in human volunteers
    • DOI 10.1016/j.vaccine.2003.11.020, PII S0264410X03008144
    • Metzger, W. G. et al. Impact of vector-priming on the immunogenicity of a live recombinant Salmonella enterica serovar typhi Ty21a vaccine expressing urease A and B from Helicobacter pylori in human volunteers. Vaccine 22, 2273-2277 (2004). (Pubitemid 38626066)
    • (2004) Vaccine , vol.22 , Issue.17-18 , pp. 2273-2277
    • Metzger, W.G.1    Mansouri, E.2    Kronawitter, M.3    Diescher, S.4    Soerensen, M.5    Hurwitz, R.6    Bumann, D.7    Aebischer, T.8    Von Specht, B.-U.9    Meyer, T.F.10
  • 55
    • 48249087613 scopus 로고    scopus 로고
    • Correlation of T cell response and bacterial clearance in human volunteers challenged with Helicobacter pylori revealed by randomised controlled vaccination with Ty21a-based Salmonella vaccines
    • Aebischer, T et al. Correlation of T cell response and bacterial clearance in human volunteers challenged with Helicobacter pylori revealed by randomised controlled vaccination with Ty21a-based Salmonella vaccines. Gut 57, 1065-1072 (2008).
    • (2008) Gut , vol.57 , pp. 1065-1072
    • Aebischer, T.1
  • 57
    • 70349512606 scopus 로고    scopus 로고
    • Regulatory T cells: How do they suppress immune responses?
    • Sakaguchi, S. et al. Regulatory T cells: how do they suppress immune responses? Int. Immunol. 21, 1105-1111 (2009).
    • (2009) Int Immunol. , vol.21 , pp. 1105-1111
    • Sakaguchi, S.1
  • 58
    • 41549159660 scopus 로고    scopus 로고
    • Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces
    • Rubtsov, Y P. et al. Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces. Immunity 28, 546-558 (2008).
    • (2008) Immunity , vol.28 , pp. 546-558
    • Rubtsov, Y.P.1
  • 59
    • 25444492869 scopus 로고    scopus 로고
    • Eradication of Helicobacter pylori and resolution of gastritis in the gastric mucosa of IL-10-deficient mice
    • DOI 10.1111/j.1523-5378.2005.00349.x
    • Matsumoto, Y et al. Eradication of Helicobacter pylori and resolution of gastritis in the gastric mucosa of IL-10-deficient mice. Helicobacter 10, 407-415 (2005). (Pubitemid 41368699)
    • (2005) Helicobacter , vol.10 , Issue.5 , pp. 407-415
    • Matsumoto, Y.1    Blanchard, T.G.2    Drakes, M.L.3    Basu, M.4    Redline, R.W.5    Levine, A.D.6    Czinn, S.J.7
  • 60
    • 0037795727 scopus 로고    scopus 로고
    • + regulatory T cells is associated with a loss of regulation leading to increased pathology in Helicobacter pylori-infected mice
    • DOI 10.1046/j.1365-2249.2003.02177.x
    • Raghavan, S. et al. Absence of CD4+CD25+ regulatory T cells is associated with a loss of regulation leading to increased pathology in Helicobacter pylori-infected mice. Clin. Exp. Immunol. 132, 393-400 (2003). (Pubitemid 36713944)
    • (2003) Clinical and Experimental Immunology , vol.132 , Issue.3 , pp. 393-400
    • Raghavan, S.1    Fredriksson, M.2    Svennerholm, A.-M.3    Holmgren, J.4    Suri-Payer, E.5
  • 62
    • 33646016588 scopus 로고    scopus 로고
    • Induction of CTLA-4-mediated anergy contributes to persistent colonization in the murine model of gastric Helicobacter pylori infection
    • Anderson, K. M., Czinn, S. J., Redline, R. W. & Blanchard, T G. Induction of CTLA-4-mediated anergy contributes to persistent colonization in the murine model of gastric Helicobacter pylori infection. J. Immunol. 176, 5306-5313 (2006).
    • (2006) J. Immunol. , vol.176 , pp. 5306-5313
    • Anderson, K.M.1    Czinn, S.J.2    Redline, R.W.3    Blanchard, T.G.4
  • 63
    • 0038583518 scopus 로고    scopus 로고
    • Severe inflammation and reduced bacteria load in murine Helicobacter infection caused by lack of phagocyte oxidase activity
    • DOI 10.1086/374780
    • Blanchard, T G., Yu, F., Hsieh, C L. & Redline, R. W. Severe inflammation and reduced bacteria load in murine helicobacter infection caused by lack of phagocyte oxidase activity J. Infect. Dis. 187, 1609-1615 (2003). (Pubitemid 36578967)
    • (2003) Journal of Infectious Diseases , vol.187 , Issue.10 , pp. 1609-1615
    • Blanchard, T.G.1    Yu, F.2    Hsieh, C.-L.3    Redline, R.W.4
  • 64
    • 0028170496 scopus 로고
    • Gastric T lymphocyte responses to Helicobacter pylori in patients with H. pylori colonisation
    • Fan, X. J. et al. Gastric T lymphocyte responses to Helicobacter pylori in patients with H. pylori colonisation. Gut 35, 1379-1384 (1994).
    • (1994) Gut , vol.35 , pp. 1379-1384
    • Fan, X.J.1
  • 65
    • 0026011764 scopus 로고
    • Blood lymphocyte proliferation, cytokine secretion and appearance of T cells with activation surface markers in cultures with Helicobacter pylori. Comparison of the responses of subjects with and without antibodies to H. pylori
    • Karttunen, R. Blood lymphocyte proliferation, cytokine secretion and appearance of T cells with activation surface markers in cultures with Helicobacter pylori. Comparison of the responses of subjects with and without antibodies to H. pylori. Clin. Exp. Immunol. 83, 396-400 (1991).
    • (1991) Clin. Exp. Immunol. , vol.83 , pp. 396-400
    • Karttunen, R.1
  • 66
    • 0025250448 scopus 로고
    • Helicobacter pylori induces lymphocyte activation in peripheral blood cultures
    • Karttunen, R. Helicobacter pylori induces lymphocyte activation in peripheral blood cultures. Clin. Exp. Immunol. 82, 485-488 (1990).
    • (1990) Clin. Exp. Immunol. , vol.82 , pp. 485-488
    • Karttunen, R.1
  • 67
    • 0028913117 scopus 로고
    • Interferon gamma and interleukin 4 secreting cells in the gastric antrum in Helicobacter pylori positive and negative gastritis
    • Karttunen, R., Karttunen, T., Ekre, H. P & MacDonald, T T Interferon gamma and interleukin 4 secreting cells in the gastric antrum in Helicobacter pylori positive and negative gastritis. Gut 36, 341-345 (1995).
    • (1995) Gut , vol.36 , pp. 341-345
    • Karttunen, R.1    Karttunen, T.2    Ekre, H.P.3    MacDonald, T.T.4
  • 69
    • 3242668165 scopus 로고    scopus 로고
    • + regulatory T cells
    • DOI 10.1111/j.0300-9475.2004.01447.x
    • Raghavan, S., Suri-Payer, E. & Holmgren, J. Antigen-specific in vitro suppression of murine Helicobacter pylori-reactive immunopathological T cells by CD4CD25 regulatory T cells. Scand. J. Immunol. 60, 82-88 (2004). (Pubitemid 38943054)
    • (2004) Scandinavian Journal of Immunology , vol.60 , Issue.1-2 , pp. 82-88
    • Raghavan, S.1    Suri-Payer, E.2    Holmgren, J.3
  • 72
    • 0036081209 scopus 로고    scopus 로고
    • Clearance of Helicobacter pylori infection and resolution of postimmunization gastritis in a kinetic study of prophylactically immunized mice
    • DOI 10.1128/IAI.70.7.3529-3538.2002
    • Garhart, C A., Redline, R. W., Nedrud, J. G. & Czinn, S. J. Clearance of Helicobacter pylori infection and resolution of postimmunization gastritis in a kinetic study of prophylactically mmunized mice. Infect. Immun. 70, 3529-3538 (2002). (Pubitemid 34665989)
    • (2002) Infection and Immunity , vol.70 , Issue.7 , pp. 3529-3538
    • Garhart, C.A.1    Redline, R.W.2    Nedrud, J.G.3    Czinn, S.J.4
  • 73
    • 51249102620 scopus 로고    scopus 로고
    • Safety and mmunogenicity of an intramuscular Helicobacter pylori vaccine in noninfected volunteers: A phase i study
    • Malfertheiner, P et al. Safety and mmunogenicity of an intramuscular Helicobacter pylori vaccine in noninfected volunteers: a phase I study. Gastroenterology 135, 787-795 (2008).
    • (2008) Gastroenterology , vol.135 , pp. 787-795
    • Malfertheiner, P.1
  • 75
    • 67449126811 scopus 로고    scopus 로고
    • The CD4+ T cell-mediated IFN-gamma response to Helicobacter infection is essential for clearance and determines gastric cancer risk
    • Sayi, A. et al. The CD4+ T cell-mediated IFN-gamma response to Helicobacter infection is essential for clearance and determines gastric cancer risk. J. Immunol. 182, 7085-7101 (2009).
    • (2009) J. Immunol. , vol.182 , pp. 7085-7101
    • Sayi, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.