Novel mechanism of the vascular protector prostacyclin: Regulating microRNA expression

Biochemistry

Volumn 50, Issue 10, 2011, Pages 1691-1699

  Mohite, Anita ^a   Chillar, Annirudha ^a   So, Shui Ping ^a   Cervantes, Vanessa ^a   Ruan, Ke He ^a  

^a UNIVERSITY OF HOUSTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOCYTES; ADIPOSE TISSUE; APOPTOSIS; ARACHIDONIC ACIDS; CATALYTIC FUNCTIONS; CELL LINES; CYCLOOXYGENASES; DOWN-REGULATION; EMBRYO IMPLANTATION; HYBRID ENZYMES; LIPID DEPOSITION; MICROARRAY ANALYSIS; MICRORNA (MIRNA); MICRORNA EXPRESSION; NUCLEAR RECEPTORS; PATHOPHYSIOLOGICAL; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; PRIMARY CULTURE; SYNTHASES; UP-REGULATION;

AMINO ACIDS; CELL CULTURE; CELL DEATH; ENZYME INHIBITION; ENZYMES; GENE EXPRESSION;

GENE EXPRESSION REGULATION;

2 CHLORO 5 NITROBENZANILIDE; AMINO ACID; CAY 10441; CYCLOOXYGENASE 1; INSULIN; MICRORNA; MICRORNA 106A; MICRORNA 140; MICRORNA 148A; MICRORNA 31; MICRORNA 374; MICRORNA 466F 3; MICRORNA 467B; MICRORNA 711; MICRORNA 720; MICRORNA 7A; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROSTACYCLIN; PROSTACYCLIN RECEPTOR; PROSTACYCLIN SYNTHASE; UNCLASSIFIED DRUG;

ADIPOCYTE; ADIPOSE TISSUE; AMINO ACID METABOLISM; APOPTOSIS; ARTICLE; CATALYSIS; CELL LINE; DOWN REGULATION; DRUG MECHANISM; GENE CONTROL; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE TARGETING; LIPID STORAGE; MICROARRAY ANALYSIS; NEOPLASM; NIDATION; OBESITY; PATHOPHYSIOLOGY; PRIORITY JOURNAL; UPREGULATION; VASCULITIS;

ADIPOCYTES; ANIMALS; CELLS, CULTURED; DOWN-REGULATION; EPOPROSTENOL; HUMANS; MICE; MICRORNAS; PROTO-ONCOGENE PROTEINS C-AKT; UP-REGULATION;

EID: 79952410483     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi101654w     Document Type: Article

References (37)

1. 2) by layers of the arterial wall. An explanation for the anti-thrombotic properties of vascular endothelium Thromb. Res. 11, 323-344
2. Majerus, P. W. (1983) Arachidonate metabolism in vascular disorders J. Clin. Invest. 72, 1521-1525 (Pubitemid 14229030)
3. Vane, J. and Corin, R. E. (2003) Prostacyclin: A vascular mediator Eur. J. Vasc. Endovasc. Surg. 26, 571-578 (Pubitemid 37461770)
4. Narumiya, S., Sugimoto, Y., and Ushikubi, F. (1999) Prostanoid receptors: Structures, properties, and functions Physiol. Rev. 79, 1193-1226 (Pubitemid 29473315)
5. Wise, H. (2003) Multiple signaling options for prostacyclin Acta Pharmacol. Sin. 24, 625-630
6. Braissant, O., Foufelle, F., Scotto, C., Dauca, M., and Wahli, W. (1996) Differential expression of peroxisome proliferator-activated receptors (PPARs): Tissue distribution of PPAR-α, -β, and -γ in the adult rat Endocrinology 137, 354-366 (Pubitemid 26005011)
7. Kliewer, S. A., Forman, B. M., Blumberg, B., Ong, E. S., Borgmeyer, U., Mangelsdorf, D. J., Umesono, K., and Evans, R. M. (1994) Differential expression and activation of a family of murine peroxisome proliferator-activated receptors Proc. Natl. Acad. Sci. U.S.A. 91, 7355-7359 (Pubitemid 24226862)
8. Becker, J., Delayre-Orthez, C., Frossard, N., and Pons, F. (2006) Regulation of inflammation by PPARs: A future approach to treat lung inflammatory diseases? Fundam. Clin. Pharmacol. 20, 429-447 (Pubitemid 44393958)
9. Lefebvre, P., Chinetti, G., Fruchart, J. C., and Staels, B. (2006) Sorting out the roles of PPARα in energy metabolism and vascular homeostasis J. Clin. Invest. 116, 571-580 (Pubitemid 43326861)
10. Fajas, L., Auboeuf, D., Raspé, E., Schoonjans, K., Lefebvre, A. M., Saladin, R., Najib, J., Laville, M., Fruchart, J. C., Deeb, S., Vidal-Puig, A., Flier, J., Briggs, M. R., Staels, B., Vidal, H., and Auwerx, J. (1997) The organization, promoter analysis, and expression of the human PPARγ gene J. Biol. Chem. 272, 18779-18789 (Pubitemid 27318225)
11. Falcettia, E., Flavell, D. M., Staels, B., Tinker, A., Haworth, S. G., and Clapp, L. H. (2007) IP receptor-dependent activation of PPARγ by stable prostacyclin analogues Biochem. Biophys. Res. Commun. 360, 821-827 (Pubitemid 47077394)
12. 2 synthesis in obese Zucker rats Am. J. Physiol. 296, R715-R721
13. Massiera, F., Saint-Marc, P., Seydoux, J., Murata, T., Kobayashi, T., Narumiya, S., Guesnet, P., Amri, E. Z., Negrel, R., and Ailhaud, G. (2003) Arachidonic acid and prostacyclin signaling promote adipose tissue development: A human health concern? J. Lipid Res. 44, 271-279 (Pubitemid 37287770)
14. Páramo, J. A., Orbe, J., Beloqui, O., Colina, I., Benito, A., Rodríguez, J. A., and Díez, J. (2008) Association of age, inflammatory markers and subclinical atherosclerosis in subjects free from cardiovascular disease Med. Clin. (Barcelona) 131, 361-366
15. Stary, H. C. (2003) Atlas of Atherosclerosis: Progression and Regression, 2nd ed., Parthenon Publishing Group, New York.
16. Strong, J. P., Malcom, G. T., McMahan, C. A., Tracy, R. E., Newman, W. P., III, and Herderick, E. E. (1999) Prevalence and extent of atherosclerosis in adolescents and young adults: Implications for prevention from the Pathobiological Determinants of Atherosclerosis in Youth Study JAMA, J. Am. Med. Assoc. 281, 727-735 (Pubitemid 29113454)
17. Ruan, K. H., Deng, H., and So, S. P. (2006) Engineering of a protein with cyclooxygenase and prostacyclin synthase activities that converts arachidonic acid to prostacyclin Biochemistry 45, 14003-14011 (Pubitemid 44846189)
18. Ruan, K. H., So, S. P., Cervantes, V., Wu, H., Wijaya, C., and Jentzen, R. R. (2008) An active triple-catalytic hybrid enzyme engineered by linking cyclo-oxygenase isoform-1 to prostacyclin synthase that can constantly biosynthesize prostacyclin, the vascular protector FEBS J. 275, 5820-5829
19. Ruan, K. H., So, S. P., Wu, H., and Cervantes, V. (2008) Large-scale expression, purification, and characterization of an engineered prostacyclin-synthesizing enzyme with therapeutic potential Arch. Biochem. Biophys. 480, 41-50
20. Farh, K. K., Grimson, A., Jan, C., Lewis, B. P., Johnston, W. K., Lim, L. P., Burge, C. B., and Bartel, D. P. (2005) The widespread impact of mammalian microRNAs on mRNA repression and evolution Science 310, 1817-1821 (Pubitemid 41814382)
21. Pasquinelli, A. E., Hunter, S., and Bracht, J. (2005) MicroRNAs: A developing story Curr. Opin. Genet. Dev. 15, 200-205 (Pubitemid 40410666)
22. Ambros, V. (2004) The functions of animal microRNAs Nature 431, 350-355 (Pubitemid 39265675)
23. Du, T. and Zamore, P. D. (2007) Beginning to understand microRNA function Cell Res. 17, 661-663 (Pubitemid 47255935)
24. Hwang, H. W. and Mendell, J. T. (2006) MicroRNAs in cell proliferation, cell death, and tumorigenesis Br. J. Cancer 94, 776-780
25. Jovanovic, M. and Hengartner, M. O. (2006) miRNAs and apoptosis: RNAs to die for Oncogene 25, 6176-6187 (Pubitemid 44527848)
26. Rane, S., Sayed, D., and Abdellatif, M. (2007) MicroRNA with a MacroFunction Cell Cycle 6, 1850-1855 (Pubitemid 47327902)
27. Van Rooij, E. and Olson, E. N. (2007) MicroRNAs: Powerful new regulators of heart disease and provocative therapeutic targets J. Clin. Invest. 117, 2369-2376 (Pubitemid 47494334)
28. Blenkiron, C. and Miska, E. A. (2007) miRNAs in cancer: Approaches, aetiology, diagnostics and therapy Hum. Mol. Genet. 16, R106-R113
29. Poy, M. N., Eliasson, L., Krutzfeldt, J., Kuwajima, S., Ma, X., Macdonald, P. E., Pfeffer, S., Tuschl, T., Rajewsky, N., Rorsman, P., and Stoffel, M. (2004) A pancreatic islet-specific microRNA regulates insulin secretion Nature 432, 226-230 (Pubitemid 39545853)
30. Esau, C., Davis, S., Murray, S. F., Yu, X. X., Pandey, S. K., Pear, M., Watts, L., Booten, S. L., Graham, M., McKay, R., Subramaniam, A., Propp, S., Lollo, B. A., Freier, S., Bennett, C. F., Bhanot, S., and Monia, B. P. (2006) miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting Cell Metab. 3, 87-98
31. Rodriguez, A., Vigorito, E., Clare, S., Warren, M. V., Couttet, P., Soond, D. R., van Dongen, S., Grocock, R. J., Das, P. P., Miska, E. A., Vetrie, D., Okkenhaug, K., Enright, A. J., Dougan, G., Turner, M., and Bradley, A. (2007) Requirement of bic/microRNA-155 for normal immune function Science 316, 608-611 (Pubitemid 46683148)
32. Kajimoto, K., Naraba, H., and Iwai, N. (2006) MicroRNA and 3T3-L1 pre-adipocyte differentiation RNA 12, 1626-1632 (Pubitemid 44316027)
33. Tang, Q. Q., Zhang, J. W., and Daniel Lane, M. (2004) Sequential gene promoter interactions by C/EBPβ, C/EBPα, and PPARγ during adipogenesis Biochem. Biophys. Res. Commun. 318, 213-218
34. Yun, S. J., Kim, E. K., Tucker, D. F., Kim, C. D., Birnbaum, M. J., and Bae, S. S. (2008) Isoform-specific regulation of adipocyte differentiation by Akt/protein kinase Bα Biochem. Biophys. Res. Commun. 371, 138-143
35. Nakae, J., Kitamura, T., Kitamura, Y., Biggs, W. H., III, Arden, K. C., and Accili, D. (2003) The forkhead transcription factor Foxo1 regulates adipocyte differentiation Dev. Cell 4, 119-129 (Pubitemid 36105338)
36. Fritzius, T. and Moelling, K. (2008) Akt- and Foxo1-interacting WD-repeat-FYVE protein promotes adipogenesis EMBO J. 27, 1399-1410 (Pubitemid 351655180)
37. Kasza, Z., Fetalvero, K. M., Ding, M., Wagner, R. J., Acs, K., Guzman, A. K., Douville, K. L., Powell, R. J., Hwa, J., and Martin, K. A. (2009) Novel signaling pathways promote a paracrine wave of prostacyclin-induced vascular smooth muscle differentiation J. Mol. Cell. Cardiol. 46, 682-694