A novel method to enable SNAr reaction of aminopyrrolopyrazoles

Tetrahedron Letters

Volumn 52, Issue 14, 2011, Pages 1692-1696

  Guo, Chuangxing ^a   Dong, Liming ^a   Marakovits, Joseph ^a   Kephart, Susan ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN SERINE THREONINE KINASE INHIBITOR; PYRAZOLE DERIVATIVE; PYRIMIDINE DERIVATIVE; PYRROLE DERIVATIVE;

ACYLATION; ANALYTIC METHOD; ARTICLE; CATALYSIS; DECOMPOSITION; ELIMINATION REACTION; HYDROLYSIS; SYNTHESIS;

EID: 79952360459     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2011.01.148     Document Type: Article

References (16)

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15. a of the 3-aminopyrazole was predicted to be 4.8 using ACD Lab v11 software.
16. a) of the aminoheteroarenes was estimated using ACDLab v11 software.