-
1
-
-
34948852956
-
-
US 4 661 484
-
(a) Okushima, H.; Narimatsu, A.; Kobayashi, M.; Furuya, R.; Kitada, Y. US 4 661 484, 1987.
-
(1987)
-
-
Okushima, H.1
Narimatsu, A.2
Kobayashi, M.3
Furuya, R.4
Kitada, Y.5
-
2
-
-
0020608178
-
-
(b) Blancafort, P.; Serradell, M. N.; Castañer, J.; Thorpe, P. Drugs Future 1983, 8, 223.
-
(1983)
Drugs Future
, vol.8
, pp. 223
-
-
Blancafort, P.1
Serradell, M.N.2
Castañer, J.3
Thorpe, P.4
-
3
-
-
34948836481
-
-
US 6 262 096B1, 2001
-
(c) Kim, K. S.; Kimball, S. D.; Cai, Z.-W.; Rawlins, D. B.; Misra, R. N.; Poss, M. A.; Webster, K. R.; Hunt, J. T.; Han, W.-C. US 6 262 096B1, 2001.
-
-
-
Kim, K.S.1
Kimball, S.D.2
Cai, Z.-W.3
Rawlins, D.B.4
Misra, R.N.5
Poss, M.A.6
Webster, K.R.7
Hunt, J.T.8
Han, W.-C.9
-
6
-
-
0037035042
-
-
Yang, J.-S.; Lin, Y.-H.; Yang, C-S. Org. Lett. 2002, 4, 777.
-
(2002)
Org. Lett
, vol.4
, pp. 777
-
-
Yang, J.-S.1
Lin, Y.-H.2
Yang, C.-S.3
-
7
-
-
0013157111
-
-
Yin, J.; Zhao, M. M.; Huffman, M. A.; McNamara, J. M. Org. Lett. 2002, 4, 3481.
-
(2002)
Org. Lett
, vol.4
, pp. 3481
-
-
Yin, J.1
Zhao, M.M.2
Huffman, M.A.3
McNamara, J.M.4
-
8
-
-
20044388313
-
-
Usui, S.; Suzuki, T.; Hattori, Y.; Etoh, K.; Fujieda, H.; Nishizuka, M.; Imagawa, M.; Nakagawa, H.; Kohda, K.; Miyata, N. Bioorg. Med. Chem. Lett. 2005, 15, 1547.
-
(2005)
Bioorg. Med. Chem. Lett
, vol.15
, pp. 1547
-
-
Usui, S.1
Suzuki, T.2
Hattori, Y.3
Etoh, K.4
Fujieda, H.5
Nishizuka, M.6
Imagawa, M.7
Nakagawa, H.8
Kohda, K.9
Miyata, N.10
-
9
-
-
1842639592
-
-
Byth, K. F.; Culshaw, J. D.; Green, S.; Oakes, S. E.; Thomas, A. P. Bioorg. Med. Chem. Lett. 2004, 14, 2245.
-
(2004)
Bioorg. Med. Chem. Lett
, vol.14
, pp. 2245
-
-
Byth, K.F.1
Culshaw, J.D.2
Green, S.3
Oakes, S.E.4
Thomas, A.P.5
-
10
-
-
31144432132
-
-
Tundel, R. E.; Anderson, K. W.; Buchwald, S. L. J. Org. Chem. 2006, 71, 430.
-
(2006)
J. Org. Chem
, vol.71
, pp. 430
-
-
Tundel, R.E.1
Anderson, K.W.2
Buchwald, S.L.3
-
11
-
-
33749849177
-
-
Anderson, K. W.; Tundel, R. E.; Ikawa, T.; Altman, R. A.; Buchwald, S. L. Angew. Chem. 2006, 45, 6523.
-
(2006)
Angew. Chem
, vol.45
, pp. 6523
-
-
Anderson, K.W.1
Tundel, R.E.2
Ikawa, T.3
Altman, R.A.4
Buchwald, S.L.5
-
12
-
-
34948815819
-
-
At the time of this manuscript's preparation, a search via ACD and ACX failed to find any commercially available arylnonaflates
-
At the time of this manuscript's preparation, a search via ACD and ACX failed to find any commercially available arylnonaflates.
-
-
-
-
16
-
-
0034712156
-
-
(d) Wolfe, J. P.; Tomori, H.; Sadighi, J. P.; Yin, J.; Buchwald, S. L. J. Org. Chem. 2000, 65, 1158.
-
(2000)
J. Org. Chem
, vol.65
, pp. 1158
-
-
Wolfe, J.P.1
Tomori, H.2
Sadighi, J.P.3
Yin, J.4
Buchwald, S.L.5
-
17
-
-
3543046740
-
-
(e) Jensen, T. A.; Liang, X.; Tanner, D.; Skaerbaek, N. J. Org. Chem. 2004, 69, 4936.
-
(2004)
J. Org. Chem
, vol.69
, pp. 4936
-
-
Jensen, T.A.1
Liang, X.2
Tanner, D.3
Skaerbaek, N.4
-
18
-
-
0033597748
-
-
For examples of NaOPh in Pd-catalyzed couplings of carbamates to aryl halides, see: (a) Hartwig, J. F, Kawatsura, M, Hauck, S. I, Shaughnessy, K. H, Alcazar-Roman, L. M. J. Org. Chem. 1999, 64, 5575
-
For examples of NaOPh in Pd-catalyzed couplings of carbamates to aryl halides, see: (a) Hartwig, J. F.; Kawatsura, M.; Hauck, S. I.; Shaughnessy, K. H.; Alcazar-Roman, L. M. J. Org. Chem. 1999, 64, 5575.
-
-
-
-
19
-
-
0022012266
-
-
For the use of NaOPh in Suzuki couplings, see
-
(b) For the use of NaOPh in Suzuki couplings, see: Miyaura, N.; Yamada, K.; Suginome, H.; Suzuki, A. J. Am. Chem. Soc. 1985, 107, 972.
-
(1985)
J. Am. Chem. Soc
, vol.107
, pp. 972
-
-
Miyaura, N.1
Yamada, K.2
Suginome, H.3
Suzuki, A.4
-
20
-
-
34948908876
-
-
For the use of NaOPh in isoprene dimerization, see: Komatsu, A.; Akutagawa, S.; Someya, T. U 3859374, 1975.
-
(c) For the use of NaOPh in isoprene dimerization, see: Komatsu, A.; Akutagawa, S.; Someya, T. U 3859374, 1975.
-
-
-
-
21
-
-
33846563488
-
-
3, see: (a) Shekhar, S.; Hartwig, J. F. Organometallics 2007, 26, 340.
-
3, see: (a) Shekhar, S.; Hartwig, J. F. Organometallics 2007, 26, 340.
-
-
-
-
23
-
-
34948898793
-
-
All microwave reactions were conducted in a 2-5 mL Biotage Microwave Vial Kit with sealable cap (code no. 351521) using a magnetic stirbar. Microwave heating was performed with a single-mode cavity Emrys SmithCreator.
-
All microwave reactions were conducted in a 2-5 mL Biotage Microwave Vial Kit with sealable cap (code no. 351521) using a magnetic stirbar. Microwave heating was performed with a single-mode cavity Emrys SmithCreator.
-
-
-
-
24
-
-
34948897734
-
-
General Procedure for Compounds Shown in Table 3 A 2-5 mL Biotage microwave vial was charged with the aryl halide (1.10 mmol, sodium phenolate (191 mg, 1.65 mmol, Pd2(dba)3 (12.6 mg, 0.0137 mmol, 2.5 mol% of Pd, and Xantphos (19.1 mg, 0.0330 mmol, 3.0 mol, followed by degassed 1,4-dioxane (6.50 mL, The mixture was stirred while degassing with argon for 1 min. The heteroaryl amine (1.21 mmol) was added last, the vial was immediately capped and sealed, then heated at 80°C for 2 h. After cooling to r.t, the mixture was diluted with EtOAc (400 mL, washed with 1 N aq NaOH (3 x 100 mL) and brine (100 mL, dried over anhyd Na2SO4, filtered, and the solvent removed under vacuum. The resulting residue was purified over silica gel (12 g, hexanes-EtOAc) and the product was freeze-dried from MeCN-H2O to provide the pure product
-
2O to provide the pure product.
-
-
-
-
25
-
-
0033531744
-
-
For studies on the scope and limitations of Pd-catalyzed formation of biarylethers from sodium phenolates, see: (a) Mann, G, Incarvito, C, Rheingold, A. L, Hartwig, J. F. J. Am. Chem. Soc. 1999, 121, 3224
-
For studies on the scope and limitations of Pd-catalyzed formation of biarylethers from sodium phenolates, see: (a) Mann, G.; Incarvito, C.; Rheingold, A. L.; Hartwig, J. F. J. Am. Chem. Soc. 1999, 121, 3224.
-
-
-
-
26
-
-
0037047555
-
-
(b) Kataoka, N.; Shelby, Q.; Stambuli, J. P.; Hartwig, J. F. J. Org. Chem. 2002, 67, 5553.
-
(2002)
J. Org. Chem
, vol.67
, pp. 5553
-
-
Kataoka, N.1
Shelby, Q.2
Stambuli, J.P.3
Hartwig, J.F.4
-
27
-
-
0033549049
-
-
(c) Aranyos, A.; Old, D. W.; Kiyomori, A.; Wolfe, J. P.; Sadighi, J. P.; Buchwald, S. L. J. Am. Chem. Soc. 1999, 121, 4369.
-
(1999)
J. Am. Chem. Soc
, vol.121
, pp. 4369
-
-
Aranyos, A.1
Old, D.W.2
Kiyomori, A.3
Wolfe, J.P.4
Sadighi, J.P.5
Buchwald, S.L.6
|