Brain glucose transporter protein 2 and sporadic alzheimer's disease

Translational Neuroscience

Volumn 1, Issue 3, 2010, Pages 200-206

  Šalković Petrišić, Melita ^a   Riederer, Peter ^b  

^a UNIVERSITY OF ZAGREB   (Croatia)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Animal model; Glucose transporter protein 2; Sporadic Alzheimer's disease; Streptozotocin Intracerebroventricular administration

Indexed keywords

GLUCOSE TRANSPORTER 1; GLUCOSE TRANSPORTER 2; GLUCOSE TRANSPORTER 3; GLUCOSE TRANSPORTER 4; INSULIN; ISOPROTEIN; STREPTOZOCIN;

ALZHEIMER DISEASE; ARTICLE; BRAIN LEVEL; BRAIN METABOLISM; DISEASE COURSE; GLUCOSE UTILIZATION; HUMAN; INSULIN METABOLISM; MOLECULAR PATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION;

EID: 79952345722     PISSN: 20813856     EISSN: 20816936     Source Type: Journal    
DOI: 10.2478/v10134-010-0030-y     Document Type: Article

References (74)

1. Hoyer S., Glucose metabolism and insulin receptor signal transduction in Alzheimer's disease, Eur. J. Pharmacol., 2007, 490, 115-125
2. Maher F., Vannucci S.J., Simpson I.A., Glucose transporter proteins in brain, FASEB J, 1994, 8, 1003-1011 (Pubitemid 24338544)
3. McEwen B.S., Reagan L.P., Glucose transporter expression in the central nervous system: Relationship to synaptic function, Eur. J. Pharmacol., 2004, 490, 13-24 (Pubitemid 38482158)
4. Duelli R., Kuschinsky W., Brain glucose transporters: Relationship to local energy demand, News Physiol. Sci., 2001, 16, 71-76 (Pubitemid 33578326)
5. Vannucci S.J., Koehler-Stec E.M., Li K., Reynolds T.H., Clark R., Simpson I.A., GLUT4 glucose transporter expression in rodent brain: Effect of diabetes, Brain Res., 1998, 797, 1-11 (Pubitemid 28331484)
6. Grillo C.A., Piroli G.G., Hendry R.M., Reagan L.P., Insulin-stimulated translocation of GLUT4 to the plasma membrane in rat hippocampus is PI3-kinase dependent, Brain Res., 2009, 1296, 35-45
7. Apelt J., Mehlhorn G., Schliebs R., Insulin-sensitive GLUT4 glucose transporters are colocalized with GLUT3-expressing cells and demonstrate a chemically distinct neuronspecific localization in rat brain, J. Neurosci. Res., 1999, 57, 693-705 (Pubitemid 29411483)
8. Piroli G.G., Grillo C.A., Charron M.J., McEwen B.J., Reagan l.P., Biphasic effects of stress upon GLUT8 glucose transporter expression and trafficking in the diabetic rat hippocampus, Brain Res., 2004, 1006, 28-35 (Pubitemid 38392079)
9. Olson A.L., Pessin J.E., Structure, function, and regulation of the mammalian facilitative glucose transporter gene family, Annu. Rev. Nutr., 1996, 16, 235-256 (Pubitemid 26286854)
10. Leloup C., Arluison M., Lepetit N., Cartier N., Marfaing-Jallat P., Ferre P. et al., Glucose transporter 2 (GLUT2): Expression in specific brain nuclei, Brain Res., 1994, 638, 221-226 (Pubitemid 24063308)
11. Arluison M., Quignon M., Nguyen P., Thorens B., Leloup C., Penicaud L., Distribution and anatomical localization of the glucose transporter 2 (GLUT2) in the adult rat brain-an immunohistochemical study, J. Chem. Neuroanat., 2004, 28, 117-136 (Pubitemid 39336524)
12. Arluison M., Quignon M., Thorens B., Leloup C., Penicaud L., Immunocytochemical localization of the glucose transporter 2 (GLUT2) in the adult rat brain. II. Electron microscopic study, J. Chem. Neuroanat., 2004, 28, 137-146 (Pubitemid 39336525)
13. Pénicaud L., Leloup C., Lorsignol A., Alquier T., Guillod E., Brain glucose sensing mechanism and glucose homeostasis, Curr. Opin. Clin. Nutr. Metab. Care, 2002, 5, 539-543 (Pubitemid 40684650)
14. Levin B.E., Glucosensing neurons do more than just sense glucose, Int. J. Obes. Relat. Metab. Disord., 2001, 25 Suppl 5, S68-72 (Pubitemid 34146327)
15. Santos M.S., Pereira E.M., Carvaho A.P., Stimulation of immunoreactive insulin release by glucose in rat brain synaptosomes, NeuroChem. Res., 1999, 24, 33-36 (Pubitemid 29067773)
16. Li B., Xi X., Roane D.S., Ryan D.H., Martin R.J., Distribution of glucokinase, glucose transporter GLUT2, sulfonylurea receptor-1, glucagon-like peptide-1 receptor and neuropeptide Y messenger RNAs in rat brain by quantitative real time RT-PCR, Brain Res. Mol. Brain. Res., 2003, 113,139-142 (Pubitemid 36579076)
17. Banks W.A., The source of cerebral insulin, Eur. J. Pharmacol., 2004, 490, 5-12 (Pubitemid 38482157)
18. Wozniak M., Rydzewski B., Baker S.P., Raizada M.K., The cellular and physiological actions of insulin in the central nervous system, Neurochem. Int., 1993, 22, 1-10
19. van Houten M., Posner B.I., Kopriwa B.M., Brawer J.R., Insulin-binding sites in the rat brain: In vivo localization to the circumventricular organs by quantitative radioautography, Endocrinology, 1979, 105, 666-673 (Pubitemid 9257453)
20. van Houten M., Posner B.I., Kopriwa B.M., Brawer J.R., Insulin binding sites localized to nerve terminals in rat median eminence and arcuate nucleus, Science, 1980, 207, 1081-1083 (Pubitemid 10105157)
21. Unger J., McNeill T.H., Moxley R.T.3rd, White M., Moss A., Livingston J.N., Distribution of insulin receptor-like immunoreactivity in the rat forebrain, Neuroscience, 1989, 31, 143-157 (Pubitemid 19209704)
22. Abbott M.A., Wells D.G., Fallon J.R., The insulin receptor tyrosine kinase substrate p 58/53 and the insulin receptor are components of CNS synapses, J. Neurosci., 1999, 19, 7300-7308 (Pubitemid 29404586)
23. Johnston A.M., Pirola L., Van Obberghen E., Molecular mechanisms of insulin receptor substrate protein-mediated modulation of insulin signalling, FEBS Lett., 2003, 546, 32-36 (Pubitemid 36789763)
24. Lester-Coll N., Rivera E.J., Soscia S.J., Doiron K., Wands J.R., de la Monte S.M., Intracerebral streptozotocin model of type 3 diabetes: Relevance to sporadic Alzheimer's's disease, J. Alzheimer'ss Dis., 2006, 9, 13-33
25. Šalkovic-Petrišic M., Osmanovic J., Grünblatt E., Riederer P., Hoyer S., Modeling sporadic Alzheimer's's disease: The insulin resistant brain state generates multiple long-term morphobiological abnormalities including hyperphosphorylated tau protein and amyloidbeta, J. Alzheimer'ss Dis., 2009, 18, 729-750
26. Zhao W., Chen H., Xu H., Moore E., Meiri N., Quon M.J., et al., Brain insulin receptors and spatial memory, J. Biol. Chem., 1999, 274, 34893-34902
27. Park C.R., Cognitive effects of insulin in the central nervous system, Neurosci. Biobehav. Rev., 2001, 25, 311-323 (Pubitemid 32624374)
28. Zhao W.Q., Chen H., Quon M.H., Alkon D.L., Insulin and the insulin receptor in experimental models of learning and memory, Eur. J. Pharmacol., 2004, 490, 71-81 (Pubitemid 38482161)
29. Moosavi M., Naghdi N., Maghsoudi N., Asl S.Z., The effect of intrahippocampal insulin microinjection on spatial learning and memory, Horm. Behav., 2006, 50, 748-752 (Pubitemid 44738856)
30. Reagan L.P., Glucose, stress and hippocampal neuronal vulnerability, Int. Rev. Neurobiol., 2002, 51, 289-324
31. Simpson I.A., Davies P., Decreased concentrations of GLUT1 and GLUT3 glucose transporters in the brains of patients with Alzheimer's's disease, Ann. Neurol., 1994, 35, 546-551 (Pubitemid 24153837)
32. Patil S., Melrose J., Chan C., Involvement of astroglial ceramide in palmitic acid-induced Alzheimer's-like changes in primary neurons, Eur. J. Neurosci., 2007, 26, 2131-2141 (Pubitemid 47620475)
33. Harik S.I., Changes in the glucose transporter of brain capillaries, Can. J. Physiol. Pharmacol., 1992, 70 Suppl, S113-117 (Pubitemid 23091614)
34. Liu Y., Liu F., Iqbal K., Grundke-Iqbal I., Gong C.X., Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer's disease, FEBS Lett., 2008, 582, 359-364
35. Kalaria R.N., Harik S.I., Reduced glucose transporter at the blood-brain barrier and in cerebral cortex in Alzheimer's disease, J. Neurochem., 1989, 53, 1083-1088 (Pubitemid 19238473)
36. Liu F., Iqbal K., Grundke-Iqbal I., Hart G.W., Gong C.X., O-GlcNAcylation regulates phosphorylation of tau: A mechanism involved in Alzheimer's's disease, Proc. Natl Acad. Sci. USA, 2004, 101,10804-10809 (Pubitemid 38955823)
37. Hsiao K., Chapman P., Nilsen S., Eckman C., Harigaya Y., Younkin S., et al., Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice, Science, 1996, 274, 99-102 (Pubitemid 26332733)
38. Bigl M., Apelt J., Eschrich K., Schliebs R., Cortical glucose metabolism is altered in aged transgenic Tg2576 mice mice that demonstrate Alzheimer's plaque pathology, J. Neural Transm., 2003, 110, 77-94 (Pubitemid 36135556)
39. Kouznetsova E., Klingner M., Sorger D., Sabri O., Grossmann U., Steinbach J., et al., Developmental and amyloid plaque-related changes in cerebral cortical capillaries in transgenic Tg2576 mice Alzheimer's mice, Int. J. Dev. Neurosci., 2006, 24, 187-193 (Pubitemid 43294625)
40. Hooijmans C.R., Graven C., Dederen P.J., Tanila H., van Groen T., Kiliaan A.J., Amyloid beta deposition is related to decreased glucose transporter-1 levels and hippocampal atrophy in brains of aged APP/ PS1 mice, Brain Res., 2007, 1181, 93-103 (Pubitemid 350050914)
41. Um H.S., Kang E.B., Leem Y.H., Cho I.H., Yang C.H., Chae K.R., et al., Exercise training acts as a therapeutic strategy for reduction of the pathogenic phenotypes for Alzheimer's's disease in an NSE/APPswtransgenic model, Int. J. Mol. Med., 2008, 22, 529-539
42. Lannert H., Hoyer S., Intracerebroventricular administration of streptozotocin causes longterm diminutions in learning and memory abilities and in cerebral energy metabolism in adult rats, Behav. Neurosci., 1998, 112, 1199-1208 (Pubitemid 28519002)
43. Šalkovic-Petrišic M., Hoyer S., Central insulin resistance as a trigger for sporadic Alzheimer's-like pathology: An experimental approach, J. Neural. Transm. Suppl., 2007, 72, 217-233
44. Weinstock M., Shoham S., Rat models of dementia based on reductions in regional glucose metabolism, cerebral blood flow and cytochrome oxidase activity, J. Neural. Transm., 2004, 111, 347-366 (Pubitemid 38316610)
45. Šalkovic-Petrišic M., Tribl F., Schmidt M., Hoyer S., Riederer P., Alzheimer's-like changes in protein kinase B and glycogen synthase kinase-3 in rat frontal cortex and hippocampus after damage to the insulin signalling pathway, J. Neurochem., 2006, 96, 1005-1015
46. Grünblatt E., Šalkovic-Petrišic M., Osmanovic J., Riederer P., Hoyer S., Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau protein, J. Neurochem., 2007, 101, 757-770 (Pubitemid 46633313)
47. Löffler T, Lee S.K., Nöldner M, Chatterjee S.S., Hoyer S., Schliebs R., Effect of Ginkgo biloba extract (EGb761) on glucose metabolismrelated markers in streptozotocin-damaged rat brain. J Neural Transm. 2001, 108:1457-1474 (Pubitemid 34020449)
48. Szkudelski T., The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas, Physiol. Res., 2001, 50, 336-346
49. Blondel O., Portha B., Early appearance of in vivo insulin resistance in adult streptozotocininjected rats, Diabet. Metab., 1989, 15, 382-387 (Pubitemid 20076229)
50. Kadowaki T., Kasuga M., Akanuma Y., Ezaki O., Takaku F., Decreased autophosphorylation of the insulin receptor-kinase in streptozotocindiabetic rats, J. Biol. Chem., 1984, 259,14208-14216 (Pubitemid 15223998)
51. Giorgino F., Chen J.H., Smith R.J., Changes in tyrosine phosphorylation of insulin receptors and a 170,000 molecular weight nonreceptor protein in vivo in skeletal muscle of streptozotocin-induced diabetic rats: Effects of insulin and glucose, Endocrinology, 1992, 130, 1433-1444
52. Schnedl W.J., Ferber S., Johnson J.H., Newgard C.B., STZ transport and cytotoxicity. Specific enhancement in GLUT2-expressing cells, Diabetes, 1994, 43, 1326-1333
53. Thulesen J., Orskov C., Holst J.J., Poulsen S.S., Short-term insulin treatment prevents the diabetogenic action of streptozotocin in rats, Endocrinology, 1997, 138, 62-68 (Pubitemid 27009406)
54. De Vos A., Heimberg H., Quartier E., Huypens P., Bouwens L., Pipeleers D., et al., Human and rat beta cells differ in glucose transporter but not in glucokinase gene expression, J. Clin. Invest., 1995, 96, 2489-2495
55. Hosokawa M., Dolci W., Thorens B., Differential sensitivity of GLUT1- and GLUT2- expressing beta cells to streptozotocin, Biochem. Biophys. Res. Commun., 2001, 289, 1114-1117 (Pubitemid 34076306)
56. Gai W., Schott-Ohly P., Schulte im Walde S., Gleichmann H., Differential target molecules for toxicity induced by streptozotocin and alloxan in pancreatic islets of mice in vitro, Exp. Clin. Endocrinol. Diabetes, 2004, 112, 29-37 (Pubitemid 38220430)
57. Lenzen S., Oxidative stress: The vulnerable beta-cell, Biochem. Soc. Trans., 2008, 36, 343-347
58. Wang Z., Gleichmann H., Glucose transporter 2 expression: Prevention of streptozotocininduced reduction in beta-cells with 5-thio-D-glucose, Exp. Clin. Endocrinol. Diabetes, 1995, 103 Suppl 2, 83-97
59. Ganda O.P., Rossini A.A., Like A.A., Studies on streptozotocin diabetes, Diabetes, 1976, 25, 595-603
60. Masiello P., Cubeddu T.L., Frosina G., Bergamini E., Protective effect of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase, against streptozotocininduced diabetes, Diabetologia, 1985, 28, 683-686 (Pubitemid 16226407)
61. Masiello P., Novelli M., Fierabracci V., Bergamini E., Protection by 3-aminobenzamide and nicotinamide against streptozotocininduced beta-cell toxicity in vivo and in vitro, Res. Commun. Chem. Pathol. Pharmacol., 1990, 69, 17-32 (Pubitemid 20231903)
62. Šalkovic M., Sabolic I., Lackovic Z., Striatal dopaminergic D1 and D2 receptors after intracerebroventricular application of alloxan and streptozotocin in rat, J. Neural. Transm. Gen. Sect., 1995, 100, 137-145
63. Brant A.M., Jess T.J., Milligan G., Brown C.M., Gould G.W., Immunological analysis of glucose transporters expressed in different regions of the rat brain and central nervous system, Biochem. Biophys. Res. Commun., 1993, 192, 1297-1302 (Pubitemid 23218553)
64. Ngarmukos C., Baur E.L., Kumagai A.K., Co-localization of GLUT1 and GLUT4 in the blood-brain barrier of the rat ventromedial hypothalamus, Brain Res., 2001, 900, 1-8 (Pubitemid 32452259)
65. Nitsch R., Hoyer S., Local action of the diabetogenic drug, streptozotocin, on glucose and energy metabolism in rat brain cortex, Neurosci. Lett., 2001, 128, 199-202
66. Plaschke K., Hoyer S., Action of the diabetogenic drug streptozotocin on glycolytic and glycogenolytic metabolism in adult rat brain cortex and hippocampus, Int. J. Dev. Neurosci., 1993, 11, 477-483
67. Hoyer S., Lannert H., Long-term abnormalities in brain glucose/ energy metabolism after inhibition of the neuronal insulin receptor: Implication of tau-protein, J. Neural. Transm. Suppl., 2007, 72, 195-202
68. Grieb P., Kryczka T., Fiedorowicz M., Frontczak-Baniewicz M., Walski M., Expansion of the Golgi apparatus in rat cerebral cortex following intracerebroventricular injections of streptozotocin, Acta Neurobiol. Exp. (Wars), 2004, 64, 481-489 (Pubitemid 39576426)
69. Tahirovic I., Sofic E., Sapcanin A., Gavrankapetanovic I., Bach- Rojecky L., Šalkovic-Petrišic M., et al., Reduced brain antioxidant capacity in rat models of betacytotoxic-induced experimental sporadic Alzheimer's's disease and diabetes mellitus, Neurochem. Res., 2007, 32, 1709-1717 (Pubitemid 47428865)
70. Sapcanin A., Sofic E., Tahirovic I., Šalkovic-Petrišic M., Hoyer S., Riederer P., Antioxidant capacity in rat brain after intracerebroventricular treatment with streptozotocin and alloxan- a preliminary study, Neurotox. Res., 2008, 13, 97-104
71. Duelli R., Maurer M.H., Staudt R., Sokoloff L., Kuschinsky W., Correlation between local glucose transporter densities and local 3-O-methylglucose transport in rat brain, Neurosci. Lett., 2001, 310, 101-104 (Pubitemid 32822814)
72. Landrigan P.J., Sonawane B., Butler R.N., Trasande L., Callan R., Droller D., Early environmental origins of neurodegenerative disease in later life, Environ. Health Perspect., 2005, 113, 1230-1233 (Pubitemid 41387665)
73. de la Monte S.M., Tong M., Lawton M., Longato L., Nitrosamine exposure exacerbates high fat diet-mediated type 2 diabetes mellitus, non-alcoholic steatohepatitis, and neurodegeneration with cognitive impairment, Mol. Neurodegener., 2009, 4, 54
74. de la Monte S.M., Tong M., Mechanisms of nitrosamine-mediated neurodegeneration: Potential relevance to sporadic Alzheimer's disease, J. Alzheimer's Dis., 2009, 17, 817-825