RIP2-mediated LKB1 deletion causes axon degeneration in the spinal cord and hind-limb paralysis

DMM Disease Models and Mechanisms

Volumn 4, Issue 2, 2011, Pages 193-202

  Sun, Gao ^a   Reynolds, Richard ^a   Leclerc, Isabelle ^a   Rutter, Guy A ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PROTEIN KINASE LKB1; RAT INSULIN 2 PROMOTER; TUBULIN; TUMOR PROMOTER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; CELL INFILTRATION; CELL STRUCTURE; CONTROLLED STUDY; DEMYELINATION; GENE; GENE DELETION; GENE MUTATION; HIND LIMB PARALYSIS; IMMUNOFLUORESCENCE TEST; KNOCKOUT MOUSE; LYMPHOCYTIC INFILTRATION; MICROTUBULE; MOUSE; NERVE FIBER DEGENERATION; NEUROFILAMENT; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PARALYSIS; PRIORITY JOURNAL; PRKAA1 GENE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SPINAL CORD; SPINAL CORD ATROPHY; SPINOCEREBELLAR TRACT; SPINOTHALAMIC TRACT; TRANSGENE; TUMOR SUPPRESSOR GENE; WESTERN BLOTTING; WHITE MATTER;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; AXONS; CATALYTIC DOMAIN; CELL MOVEMENT; GENE DELETION; HINDLIMB; INTEGRASES; MACROPHAGES; MICE; MICE, KNOCKOUT; MICROTUBULES; MOTOR ACTIVITY; NERVE DEGENERATION; PARALYSIS; PROTEIN-SERINE-THREONINE KINASES; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASE 2; SENSORY RECEPTOR CELLS; SIGNAL TRANSDUCTION; SPINAL CORD; TRANSGENES;

MUS;

EID: 79952331147     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.006833     Document Type: Article

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