Modulation of steroidogenic gene expression and hormone synthesis in H295R cells exposed to PCP and TCP

Toxicology

Volumn 282, Issue 3, 2011, Pages 146-153

  Ma, Yanbo ^a,b   Liu, Chunsheng ^a   Lam, Paul K S ^c   Wu, Rudolf S S ^d   Giesy, John P ^c,d,e,f,g   Hecker, Markus ^e   Zhang, Xiaowei ^e   Zhou, Bingsheng ^a  

^a INSTITUTE OF HYDROBIOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c CITY UNIVERSITY OF HONG KONG   (Hong Kong)

^d UNIVERSITY OF HONG KONG   (Hong Kong)

^e UNIVERSITY OF SASKATCHEWAN   (Canada)

^f KING SAUD UNIVERSITY   (Saudi Arabia)

^g MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

CAMP; Chlorophenol; Endocrine disruption; Gene expression; H295R; Steroid hormone

Indexed keywords

2,4,6 TRICHLOROPHENOL; 3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; AROMATASE; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CYCLIC AMP; CYTOCHROME P450 17; ESTRADIOL; PENTACHLOROPHENOL; STEROIDOGENIC ACUTE REGULATORY PROTEIN; TESTOSTERONE 17BETA DEHYDROGENASE;

ADRENAL CORTEX CARCINOMA; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION REGULATION; HORMONE SYNTHESIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; STEROIDOGENESIS; TESTOSTERONE SYNTHESIS;

EID: 79952310970     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2011.01.024     Document Type: Article

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