Nitrophenols isolated from diesel exhaust particles regulate steroidogenic gene expression and steroid synthesis in the human H295R adrenocortical cell line

Toxicology and Applied Pharmacology

Volumn 229, Issue 1, 2008, Pages 109-120

  Furuta, Chie ^a,b   Noda, Shiho ^b   Li, ChunMei ^c   Suzuki, Akira K ^c   Taneda, Shinji ^c   Watanabe, Gen ^a,b   Taya, Kazuyoshi ^a,b  

^a GIFU UNIVERSITY   (Japan)

^b Faculty of Agriculture   (Japan)

^c NATIONAL INSTITUTE FOR ENVIRONMENTAL STUDIES   (Japan)

Author keywords

3 methyl 4 nitrophenol; 4 nitro 3 phenylphenol; Adrenocortical H295R cell; Diesel exhaust particles; Steroidogenesis; Steroidogenic enzymes

Indexed keywords

3 METHYL 4 NITROPHENOL; 3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; 4 NITRO 3 PHENYLPHENOL; 8 BROMO CYCLIC AMP; AROMATASE; CYTOCHROME P450 17; ESTRADIOL; HYDROCORTISONE; NITROPHENOL; PROGESTERONE; STEROID; STEROID 21 MONOOXYGENASE; TESTOSTERONE; TESTOSTERONE 17BETA DEHYDROGENASE;

ADRENAL CORTEX CELL; ARTICLE; CONTROLLED STUDY; EXHAUST GAS; GENE EXPRESSION; HUMAN; HUMAN CELL; PROGESTERONE RELEASE; STEROIDOGENESIS;

8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; BIPHENYL COMPOUNDS; CELL LINE, TUMOR; CRESOLS; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTRADIOL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; HYDROCORTISONE; HYDROXYSTEROID DEHYDROGENASES; NITROPHENOLS; PHOSPHOPROTEINS; PROGESTERONE; TESTOSTERONE; VEHICLE EMISSIONS;

EID: 42749087549     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2008.01.026     Document Type: Article

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