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Volumn 6, Issue 3, 2011, Pages

Sequencing illustrates the transcriptional response of Legionella pneumophila during infection and identifies seventy novel small non-coding RNAs

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY RNA; RIBOSOME RNA; RNA 6S; UNCLASSIFIED DRUG; UNTRANSLATED RNA; BACTERIAL RNA; SMALL UNTRANSLATED RNA;

EID: 79952300775     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0017570     Document Type: Article
Times cited : (71)

References (54)
  • 1
    • 70350141708 scopus 로고    scopus 로고
    • Legionella, protozoa, and biofilms: interactions within complex microbial systems
    • Taylor M, Ross K, Bentham R, (2009) Legionella, protozoa, and biofilms: interactions within complex microbial systems. Microb Ecol 58: 538-547.
    • (2009) Microb Ecol , vol.58 , pp. 538-547
    • Taylor, M.1    Ross, K.2    Bentham, R.3
  • 2
    • 33845321418 scopus 로고    scopus 로고
    • Occurrence of infected amoebae in cooling towers compared with natural aquatic environments: implications for emerging pathogens
    • Berk SG, Gunderson JH, Newsome AL, Farone AL, Hayes BJ, et al. (2006) Occurrence of infected amoebae in cooling towers compared with natural aquatic environments: implications for emerging pathogens. Environ Sci Technol 40: 7440-7444.
    • (2006) Environ Sci Technol , vol.40 , pp. 7440-7444
    • Berk, S.G.1    Gunderson, J.H.2    Newsome, A.L.3    Farone, A.L.4    Hayes, B.J.5
  • 3
    • 0034566380 scopus 로고    scopus 로고
    • Legionella pneumophila pathogesesis: a fateful journey from amoebae to macrophages
    • Swanson MS, Hammer BK, (2000) Legionella pneumophila pathogesesis: a fateful journey from amoebae to macrophages. Annu Rev Microbiol 54: 567-613.
    • (2000) Annu Rev Microbiol , vol.54 , pp. 567-613
    • Swanson, M.S.1    Hammer, B.K.2
  • 4
    • 3142512687 scopus 로고    scopus 로고
    • Differentiate to thrive: lessons from the Legionella pneumophila life cycle
    • Molofsky AB, Swanson MS, (2004) Differentiate to thrive: lessons from the Legionella pneumophila life cycle. Mol Microbiol 53: 29-40.
    • (2004) Mol Microbiol , vol.53 , pp. 29-40
    • Molofsky, A.B.1    Swanson, M.S.2
  • 5
    • 0142125296 scopus 로고    scopus 로고
    • Legionella pneumophila CsrA is a pivotal repressor of transmission traits and activator of replication
    • Molofsky AB, Swanson MS, (2003) Legionella pneumophila CsrA is a pivotal repressor of transmission traits and activator of replication. Mol Microbiol 50: 445-461.
    • (2003) Mol Microbiol , vol.50 , pp. 445-461
    • Molofsky, A.B.1    Swanson, M.S.2
  • 6
    • 33745767998 scopus 로고    scopus 로고
    • Virulence strategies for infecting phagocytes deduced from the in vivo transcriptional program of Legionella pneumophila
    • Bruggemann H, Hagman A, Jules M, Sismeiro O, Dillies MA, et al. (2006) Virulence strategies for infecting phagocytes deduced from the in vivo transcriptional program of Legionella pneumophila. Cell Microbiol 8: 1228-1240.
    • (2006) Cell Microbiol , vol.8 , pp. 1228-1240
    • Bruggemann, H.1    Hagman, A.2    Jules, M.3    Sismeiro, O.4    Dillies, M.A.5
  • 7
    • 74949137952 scopus 로고    scopus 로고
    • A single-base resolution map of an archaeal transcriptome
    • Wurtzel O, Sapra R, Chen F, Zhu Y, Simmons BA, et al. (2010) A single-base resolution map of an archaeal transcriptome. Genome Res 20: 133-141.
    • (2010) Genome Res , vol.20 , pp. 133-141
    • Wurtzel, O.1    Sapra, R.2    Chen, F.3    Zhu, Y.4    Simmons, B.A.5
  • 9
    • 77950349491 scopus 로고    scopus 로고
    • Deep sequencing-based discovery of the Chlamydia trachomatis transcriptome
    • Albrecht M, Sharma CM, Reinhardt R, Vogel J, Rudel T, (2010) Deep sequencing-based discovery of the Chlamydia trachomatis transcriptome. Nucleic Acids Res 38: 868-877.
    • (2010) Nucleic Acids Res , vol.38 , pp. 868-877
    • Albrecht, M.1    Sharma, C.M.2    Reinhardt, R.3    Vogel, J.4    Rudel, T.5
  • 10
    • 68249102779 scopus 로고    scopus 로고
    • A strand-specific RNA-Seq analysis of the transcriptome of the typhoid bacillus Salmonella typhi
    • Perkins TT, Kingsley RA, Fookes MC, Gardner PP, James KD, et al. (2009) A strand-specific RNA-Seq analysis of the transcriptome of the typhoid bacillus Salmonella typhi. PLoS Genet 5: e1000569.
    • (2009) PLoS Genet , vol.5
    • Perkins, T.T.1    Kingsley, R.A.2    Fookes, M.C.3    Gardner, P.P.4    James, K.D.5
  • 11
    • 71549126189 scopus 로고    scopus 로고
    • Activation of gene expression by small RNA
    • Frohlich KS, Vogel J, (2009) Activation of gene expression by small RNA. Curr Opin Microbiol 12: 674-682.
    • (2009) Curr Opin Microbiol , vol.12 , pp. 674-682
    • Frohlich, K.S.1    Vogel, J.2
  • 12
    • 33646483181 scopus 로고    scopus 로고
    • The role of RNAs in the regulation of virulence-gene expression
    • Romby P, Vandenesch F, Wagner EG, (2006) The role of RNAs in the regulation of virulence-gene expression. Curr Opin Microbiol 9: 229-236.
    • (2006) Curr Opin Microbiol , vol.9 , pp. 229-236
    • Romby, P.1    Vandenesch, F.2    Wagner, E.G.3
  • 13
    • 0033956060 scopus 로고    scopus 로고
    • The COG database: a tool for genome-scale analysis of protein functions and evolution
    • Tatusov RL, Galperin MY, Natale DA, Koonin EV, (2000) The COG database: a tool for genome-scale analysis of protein functions and evolution. Nucleic Acids Res 28: 33-36.
    • (2000) Nucleic Acids Res , vol.28 , pp. 33-36
    • Tatusov, R.L.1    Galperin, M.Y.2    Natale, D.A.3    Koonin, E.V.4
  • 14
    • 38049103107 scopus 로고    scopus 로고
    • Phosphatidylcholine synthesis is required for optimal function of Legionella pneumophila virulence determinants
    • Conover GM, Martinez-Morales F, Heidtman MI, Luo ZQ, Tang M, et al. (2008) Phosphatidylcholine synthesis is required for optimal function of Legionella pneumophila virulence determinants. Cell Microbiol 10: 514-528.
    • (2008) Cell Microbiol , vol.10 , pp. 514-528
    • Conover, G.M.1    Martinez-Morales, F.2    Heidtman, M.I.3    Luo, Z.Q.4    Tang, M.5
  • 15
    • 65249173349 scopus 로고    scopus 로고
    • SigmaS controls multiple pathways associated with intracellular multiplication of Legionella pneumophila
    • Hovel-Miner G, Pampou S, Faucher SP, Clarke M, Morozova I, et al. (2009) SigmaS controls multiple pathways associated with intracellular multiplication of Legionella pneumophila. J Bacteriol 191: 2461-2473.
    • (2009) J Bacteriol , vol.191 , pp. 2461-2473
    • Hovel-Miner, G.1    Pampou, S.2    Faucher, S.P.3    Clarke, M.4    Morozova, I.5
  • 16
    • 73649119529 scopus 로고    scopus 로고
    • Control of flagellar gene regulation in Legionella pneumophila and its relation to growth phase
    • Albert-Weissenberger C, Sahr T, Sismeiro O, Hacker J, Heuner K, et al. (2010) Control of flagellar gene regulation in Legionella pneumophila and its relation to growth phase. J Bacteriol 192: 446-455.
    • (2010) J Bacteriol , vol.192 , pp. 446-455
    • Albert-Weissenberger, C.1    Sahr, T.2    Sismeiro, O.3    Hacker, J.4    Heuner, K.5
  • 17
    • 73349084316 scopus 로고    scopus 로고
    • The metal efflux island of Legionella pneumophila is not required for survival in macrophages and amoebas
    • Kim EH, Charpentier X, Torres-Urquidy O, McEvoy MM, Rensing C, (2009) The metal efflux island of Legionella pneumophila is not required for survival in macrophages and amoebas. FEMS Microbiol Lett 301: 164-170.
    • (2009) FEMS Microbiol Lett , vol.301 , pp. 164-170
    • Kim, E.H.1    Charpentier, X.2    Torres-Urquidy, O.3    McEvoy, M.M.4    Rensing, C.5
  • 18
    • 10044263696 scopus 로고    scopus 로고
    • Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity
    • Cazalet C, Rusniok C, Bruggemann H, Zidane N, Magnier A, et al. (2004) Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity. Nat Genet 36: 1165-1173.
    • (2004) Nat Genet , vol.36 , pp. 1165-1173
    • Cazalet, C.1    Rusniok, C.2    Bruggemann, H.3    Zidane, N.4    Magnier, A.5
  • 19
    • 0021590872 scopus 로고
    • Metabolic pathways and nitrogen metabolism in Legionella pneumophila
    • Keen MG, Hoffman PS, (1984) Metabolic pathways and nitrogen metabolism in Legionella pneumophila. Curr Microbiology 11: 81-88.
    • (1984) Curr Microbiology , vol.11 , pp. 81-88
    • Keen, M.G.1    Hoffman, P.S.2
  • 20
    • 77952569352 scopus 로고    scopus 로고
    • Glucose metabolism in Legionella pneumophila: dependence on the Entner-Doudoroff pathway and connection with intracellular bacterial growth
    • Harada E, Iida K, Shiota S, Nakayama H, Yoshida S, (2010) Glucose metabolism in Legionella pneumophila: dependence on the Entner-Doudoroff pathway and connection with intracellular bacterial growth. J Bacteriol 192: 2892-2899.
    • (2010) J Bacteriol , vol.192 , pp. 2892-2899
    • Harada, E.1    Iida, K.2    Shiota, S.3    Nakayama, H.4    Yoshida, S.5
  • 21
    • 77954595080 scopus 로고    scopus 로고
    • Isotopologue profiling of Legionella pneumophila: role of serine and glucose as carbon substrates
    • Eylert E, Herrmann V, Jules M, Gillmaier N, Lautner M, et al. (2010) Isotopologue profiling of Legionella pneumophila: role of serine and glucose as carbon substrates. J Biol Chem 285: 22232-22243.
    • (2010) J Biol Chem , vol.285 , pp. 22232-22243
    • Eylert, E.1    Herrmann, V.2    Jules, M.3    Gillmaier, N.4    Lautner, M.5
  • 22
    • 14844304337 scopus 로고    scopus 로고
    • Intracellular multiplication of Legionella pneumophila depends on host cell amino acid transporter SLC1A5
    • Wieland H, Ullrich S, Lang F, Neumeister B, (2005) Intracellular multiplication of Legionella pneumophila depends on host cell amino acid transporter SLC1A5. Mol Microbiol 55: 1528-1537.
    • (2005) Mol Microbiol , vol.55 , pp. 1528-1537
    • Wieland, H.1    Ullrich, S.2    Lang, F.3    Neumeister, B.4
  • 23
    • 77956552974 scopus 로고    scopus 로고
    • ArgR-regulated genes are derepressed in the Legionella-containing vacuole
    • Hovel-Miner G, Faucher SP, Charpentier X, Shuman HA, (2010) ArgR-regulated genes are derepressed in the Legionella-containing vacuole. J Bacteriol 192: 4504-4516.
    • (2010) J Bacteriol , vol.192 , pp. 4504-4516
    • Hovel-Miner, G.1    Faucher, S.P.2    Charpentier, X.3    Shuman, H.A.4
  • 24
    • 70449372419 scopus 로고    scopus 로고
    • The TolC protein of Legionella pneumophila plays a major role in multi-drug resistance and the early steps of host invasion
    • Ferhat M, Atlan D, Vianney A, Lazzaroni JC, Doublet P, et al. (2009) The TolC protein of Legionella pneumophila plays a major role in multi-drug resistance and the early steps of host invasion. PLoS One 4: e7732.
    • (2009) PLoS One , vol.4
    • Ferhat, M.1    Atlan, D.2    Vianney, A.3    Lazzaroni, J.C.4    Doublet, P.5
  • 25
    • 33744963426 scopus 로고    scopus 로고
    • Escherichia coli interactions with Acanthamoeba: a symbiosis with environmental and clinical implications
    • Alsam S, Jeong SR, Sissons J, Dudley R, Kim KS, et al. (2006) Escherichia coli interactions with Acanthamoeba: a symbiosis with environmental and clinical implications. J Med Microbiol 55: 689-694.
    • (2006) J Med Microbiol , vol.55 , pp. 689-694
    • Alsam, S.1    Jeong, S.R.2    Sissons, J.3    Dudley, R.4    Kim, K.S.5
  • 26
    • 0034756244 scopus 로고    scopus 로고
    • Pathogenicity of Legionella pneumophila
    • Cianciotto NP, (2001) Pathogenicity of Legionella pneumophila. Int J Med Microbiol 291: 331-343.
    • (2001) Int J Med Microbiol , vol.291 , pp. 331-343
    • Cianciotto, N.P.1
  • 27
    • 1642534348 scopus 로고    scopus 로고
    • Cell biology of the intracellular infection by Legionella pneumophila
    • Molmeret M, Bitar DM, Han L, Kwaik YA, (2004) Cell biology of the intracellular infection by Legionella pneumophila. Microbes Infect 6: 129-139.
    • (2004) Microbes Infect , vol.6 , pp. 129-139
    • Molmeret, M.1    Bitar, D.M.2    Han, L.3    Kwaik, Y.A.4
  • 28
    • 42949174067 scopus 로고    scopus 로고
    • Proteomic characterization of the whole secretome of Legionella pneumophila and functional analysis of outer membrane vesicles
    • Galka F, Wai SN, Kusch H, Engelmann S, Hecker M, et al. (2008) Proteomic characterization of the whole secretome of Legionella pneumophila and functional analysis of outer membrane vesicles. Infect Immun 76: 1825-1836.
    • (2008) Infect Immun , vol.76 , pp. 1825-1836
    • Galka, F.1    Wai, S.N.2    Kusch, H.3    Engelmann, S.4    Hecker, M.5
  • 29
    • 0036840406 scopus 로고    scopus 로고
    • Characterization of the gene encoding the major secreted lysophospholipase A of Legionella pneumophila and its role in detoxification of lysophosphatidylcholine
    • Flieger A, Neumeister B, Cianciotto NP, (2002) Characterization of the gene encoding the major secreted lysophospholipase A of Legionella pneumophila and its role in detoxification of lysophosphatidylcholine. Infect Immun 70: 6094-6106.
    • (2002) Infect Immun , vol.70 , pp. 6094-6106
    • Flieger, A.1    Neumeister, B.2    Cianciotto, N.P.3
  • 30
    • 38949201066 scopus 로고    scopus 로고
    • The type II secretion system of Legionella pneumophila elaborates two aminopeptidases, as well as a metalloprotease that contributes to differential infection among protozoan hosts
    • Rossier O, Dao J, Cianciotto NP, (2008) The type II secretion system of Legionella pneumophila elaborates two aminopeptidases, as well as a metalloprotease that contributes to differential infection among protozoan hosts. Appl Environ Microbiol 74: 753-761.
    • (2008) Appl Environ Microbiol , vol.74 , pp. 753-761
    • Rossier, O.1    Dao, J.2    Cianciotto, N.P.3
  • 33
    • 65549169936 scopus 로고    scopus 로고
    • The LetA-RsmYZ-CsrA regulatory cascade, together with RpoS and PmrA, post-transcriptionally regulates stationary phase activation of Legionella pneumophila Icm/Dot effectors
    • Rasis M, Segal G, (2009) The LetA-RsmYZ-CsrA regulatory cascade, together with RpoS and PmrA, post-transcriptionally regulates stationary phase activation of Legionella pneumophila Icm/Dot effectors. Mol Microbiol 72: 995-1010.
    • (2009) Mol Microbiol , vol.72 , pp. 995-1010
    • Rasis, M.1    Segal, G.2
  • 34
    • 61749088917 scopus 로고    scopus 로고
    • Bacterial chromosome-encoded small regulatory RNAs
    • Brantl S, (2009) Bacterial chromosome-encoded small regulatory RNAs. Future Microbiol 4: 85-103.
    • (2009) Future Microbiol , vol.4 , pp. 85-103
    • Brantl, S.1
  • 35
    • 17844379221 scopus 로고    scopus 로고
    • 6S RNA is a widespread regulator of eubacterial RNA polymerase that resembles an open promoter
    • Barrick JE, Sudarsan N, Weinberg Z, Ruzzo WL, Breaker RR, (2005) 6S RNA is a widespread regulator of eubacterial RNA polymerase that resembles an open promoter. RNA 11: 774-784.
    • (2005) RNA , vol.11 , pp. 774-784
    • Barrick, J.E.1    Sudarsan, N.2    Weinberg, Z.3    Ruzzo, W.L.4    Breaker, R.R.5
  • 36
    • 77949425194 scopus 로고    scopus 로고
    • The primary transcriptome of the major human pathogen Helicobacter pylori
    • Sharma CM, Hoffmann S, Darfeuille F, Reignier J, Findeiss S, et al. (2010) The primary transcriptome of the major human pathogen Helicobacter pylori. Nature 464: 250-255.
    • (2010) Nature , vol.464 , pp. 250-255
    • Sharma, C.M.1    Hoffmann, S.2    Darfeuille, F.3    Reignier, J.4    Findeiss, S.5
  • 37
    • 75149149874 scopus 로고    scopus 로고
    • Deep RNA sequencing of L. monocytogenes reveals overlapping and extensive stationary phase and sigma B-dependent transcriptomes, including multiple highly transcribed noncoding RNAs
    • Oliver HF, Orsi RH, Ponnala L, Keich U, Wang W, et al. (2009) Deep RNA sequencing of L. monocytogenes reveals overlapping and extensive stationary phase and sigma B-dependent transcriptomes, including multiple highly transcribed noncoding RNAs. BMC Genomics 10: 641.
    • (2009) BMC Genomics , vol.10 , pp. 641
    • Oliver, H.F.1    Orsi, R.H.2    Ponnala, L.3    Keich, U.4    Wang, W.5
  • 38
    • 0031939779 scopus 로고    scopus 로고
    • A bacterial RNA that functions as both a tRNA and an mRNA
    • Muto A, Ushida C, Himeno H, (1998) A bacterial RNA that functions as both a tRNA and an mRNA. Trends Biochem Sci 23: 25-29.
    • (1998) Trends Biochem Sci , vol.23 , pp. 25-29
    • Muto, A.1    Ushida, C.2    Himeno, H.3
  • 39
    • 26244446952 scopus 로고    scopus 로고
    • Phylogenetic relationships and species differentiation of 39 Legionella species by sequence determination of the RNase P RNA gene rnpB
    • Rubin CJ, Thollesson M, Kirsebom LA, Herrmann B, (2005) Phylogenetic relationships and species differentiation of 39 Legionella species by sequence determination of the RNase P RNA gene rnpB. Int J Syst Evol Microbiol 55: 2039-2049.
    • (2005) Int J Syst Evol Microbiol , vol.55 , pp. 2039-2049
    • Rubin, C.J.1    Thollesson, M.2    Kirsebom, L.A.3    Herrmann, B.4
  • 40
    • 72049118448 scopus 로고    scopus 로고
    • Photooxidative stress-induced and abundant small RNAs in Rhodobacter sphaeroides
    • Berghoff BA, Glaeser J, Sharma CM, Vogel J, Klug G, (2009) Photooxidative stress-induced and abundant small RNAs in Rhodobacter sphaeroides. Mol Microbiol 74: 1497-1512.
    • (2009) Mol Microbiol , vol.74 , pp. 1497-1512
    • Berghoff, B.A.1    Glaeser, J.2    Sharma, C.M.3    Vogel, J.4    Klug, G.5
  • 42
    • 77958028354 scopus 로고    scopus 로고
    • Regulatory RNA in bacterial pathogens
    • Papenfort K, Vogel J, (2010) Regulatory RNA in bacterial pathogens. Cell Host Microbe 8: 116-127.
    • (2010) Cell Host Microbe , vol.8 , pp. 116-127
    • Papenfort, K.1    Vogel, J.2
  • 44
    • 16244421995 scopus 로고    scopus 로고
    • IcmS-dependent translocation of SdeA into macrophages by the Legionella pneumophila type IV secretion system
    • Bardill JP, Miller JL, Vogel JP, (2005) IcmS-dependent translocation of SdeA into macrophages by the Legionella pneumophila type IV secretion system. Mol Microbiol 56: 90-103.
    • (2005) Mol Microbiol , vol.56 , pp. 90-103
    • Bardill, J.P.1    Miller, J.L.2    Vogel, J.P.3
  • 45
    • 34249887901 scopus 로고    scopus 로고
    • Legionella pneumophila adaptation to intracellular life and the host response: clues from genomics and transcriptomics
    • Jules M, Buchrieser C, (2007) Legionella pneumophila adaptation to intracellular life and the host response: clues from genomics and transcriptomics. FEBS Lett 581: 2829-2838.
    • (2007) FEBS Lett , vol.581 , pp. 2829-2838
    • Jules, M.1    Buchrieser, C.2
  • 46
    • 0019501041 scopus 로고
    • Amino acid requirements for Legionella pneumophila growth
    • Tesh MJ, Miller RD, (1981) Amino acid requirements for Legionella pneumophila growth. J Clin Microbiol 13: 865-869.
    • (1981) J Clin Microbiol , vol.13 , pp. 865-869
    • Tesh, M.J.1    Miller, R.D.2
  • 47
    • 0032701004 scopus 로고    scopus 로고
    • Relationships between a new type IV secretion system and the icm/dot virulence system of Legionella pneumophila
    • Segal G, Russo JJ, Shuman HA, (1999) Relationships between a new type IV secretion system and the icm/dot virulence system of Legionella pneumophila. Mol Microbiol 34: 799-809.
    • (1999) Mol Microbiol , vol.34 , pp. 799-809
    • Segal, G.1    Russo, J.J.2    Shuman, H.A.3
  • 48
    • 72849114230 scopus 로고    scopus 로고
    • Prokaryotic transcriptomics: a new view on regulation, physiology and pathogenicity
    • Sorek R, Cossart P, (2010) Prokaryotic transcriptomics: a new view on regulation, physiology and pathogenicity. Nat Rev Genet 11: 9-16.
    • (2010) Nat Rev Genet , vol.11 , pp. 9-16
    • Sorek, R.1    Cossart, P.2
  • 49
    • 60549089721 scopus 로고    scopus 로고
    • Gene dosage compensation calibrates four regulatory RNAs to control Vibrio cholerae quorum sensing
    • Svenningsen SL, Tu KC, Bassler BL, (2009) Gene dosage compensation calibrates four regulatory RNAs to control Vibrio cholerae quorum sensing. EMBO J 28: 429-439.
    • (2009) EMBO J , vol.28 , pp. 429-439
    • Svenningsen, S.L.1    Tu, K.C.2    Bassler, B.L.3
  • 50
    • 3142564584 scopus 로고    scopus 로고
    • The small RNA chaperone Hfq and multiple small RNAs control quorum sensing in Vibrio harveyi and Vibrio cholerae
    • Lenz DH, Mok KC, Lilley BN, Kulkarni RV, Wingreen NS, et al. (2004) The small RNA chaperone Hfq and multiple small RNAs control quorum sensing in Vibrio harveyi and Vibrio cholerae. Cell 118: 69-82.
    • (2004) Cell , vol.118 , pp. 69-82
    • Lenz, D.H.1    Mok, K.C.2    Lilley, B.N.3    Kulkarni, R.V.4    Wingreen, N.S.5
  • 51
    • 0033979096 scopus 로고    scopus 로고
    • Expression and use of the green fluorescent protein as a reporter system in Legionella pneumophila
    • Kohler R, Bubert A, Goebel W, Steinert M, Hacker J, et al. (2000) Expression and use of the green fluorescent protein as a reporter system in Legionella pneumophila. Mol Gen Genet 262: 1060-1069.
    • (2000) Mol Gen Genet , vol.262 , pp. 1060-1069
    • Kohler, R.1    Bubert, A.2    Goebel, W.3    Steinert, M.4    Hacker, J.5
  • 52
    • 0026512947 scopus 로고
    • A quantitative model of intracellular growth of Legionella pneumophila in Acanthamoeba castellanii
    • Moffat JF, Tompkins LS, (1992) A quantitative model of intracellular growth of Legionella pneumophila in Acanthamoeba castellanii. Infect Immun 60: 296-301.
    • (1992) Infect Immun , vol.60 , pp. 296-301
    • Moffat, J.F.1    Tompkins, L.S.2
  • 54
    • 53249132629 scopus 로고    scopus 로고
    • Identification of genetic variants using bar-coded multiplexed sequencing
    • Craig DW, Pearson JV, Szelinger S, Sekar A, Redman M, et al. (2008) Identification of genetic variants using bar-coded multiplexed sequencing. Nat Methods 5: 887-893.
    • (2008) Nat Methods , vol.5 , pp. 887-893
    • Craig, D.W.1    Pearson, J.V.2    Szelinger, S.3    Sekar, A.4    Redman, M.5


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