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Volumn 232, Issue 1-2, 2011, Pages 151-157

Induction of hippocampal neurogenesis by a tolerogenic peptide that ameliorates lupus manifestations

Author keywords

A model of systemic lupus erythematosus; A tolerogenic peptide; ERK and Akt pathways; Growth and neurotrophic factors; Hippocampal neurogenesis

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BROXURIDINE; HCDR1 PEPTIDE; IMMUNOMODULATING AGENT; MITOGEN ACTIVATED PROTEIN KINASE; NERVE GROWTH FACTOR; NEURON SPECIFIC NUCLEAR PROTEIN; PROTEIN KINASE B; SOMATOMEDIN C; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 79952248042     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2010.11.001     Document Type: Article
Times cited : (19)

References (51)
  • 1
    • 0034656167 scopus 로고    scopus 로고
    • Peripheral infusion of IGF-I selectively induces neurogenesis in the adult rat hippocampus
    • Aberg M.A., Aberg N.D., Hedbacker H., Oscarsson J., Eriksson P.S. Peripheral infusion of IGF-I selectively induces neurogenesis in the adult rat hippocampus. J. Neurosci. 2000, 20:2896-2903.
    • (2000) J. Neurosci. , vol.20 , pp. 2896-2903
    • Aberg, M.A.1    Aberg, N.D.2    Hedbacker, H.3    Oscarsson, J.4    Eriksson, P.S.5
  • 2
    • 24744435759 scopus 로고    scopus 로고
    • Neurogenesis and neuroprotection induced by peripheral immunomodulatory treatment of experimental autoimmune encephalomyelitis
    • Aharoni R., Arnon R., Eilam R. Neurogenesis and neuroprotection induced by peripheral immunomodulatory treatment of experimental autoimmune encephalomyelitis. J. Neurosci. 2005, 25:8217-8228.
    • (2005) J. Neurosci. , vol.25 , pp. 8217-8228
    • Aharoni, R.1    Arnon, R.2    Eilam, R.3
  • 3
    • 30044451754 scopus 로고    scopus 로고
    • The immunomodulator glatiramer acetate augments the expression of neurotrophic factors in brains of experimental autoimmune encephalomyelitis mice
    • Aharoni R., Eilam R., Domev H., Labunskay G., Sela M., Arnon R. The immunomodulator glatiramer acetate augments the expression of neurotrophic factors in brains of experimental autoimmune encephalomyelitis mice. Proc. Natl Acad. Sci. USA 2005, 102:19045-19050.
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 19045-19050
    • Aharoni, R.1    Eilam, R.2    Domev, H.3    Labunskay, G.4    Sela, M.5    Arnon, R.6
  • 5
    • 33947696072 scopus 로고    scopus 로고
    • Neuroimmunopathology in a murine model of neuropsychiatric lupus
    • Ballok D.A. Neuroimmunopathology in a murine model of neuropsychiatric lupus. Brain Res. Rev. 2007, 54:67-79.
    • (2007) Brain Res. Rev. , vol.54 , pp. 67-79
    • Ballok, D.A.1
  • 6
    • 59249098539 scopus 로고    scopus 로고
    • Adult hippocampal neurogenesis: regulation, functional implications, and contribution to disease pathology
    • Balu D.T., Lucki I. Adult hippocampal neurogenesis: regulation, functional implications, and contribution to disease pathology. Neurosci. Biobehav. Rev. 2009, 33:232-252.
    • (2009) Neurosci. Biobehav. Rev. , vol.33 , pp. 232-252
    • Balu, D.T.1    Lucki, I.2
  • 8
    • 0028902623 scopus 로고
    • Intrinsic and extrinsic factors regulating vertebrate neurogenesis
    • Calof A.L. Intrinsic and extrinsic factors regulating vertebrate neurogenesis. Curr. Opin. Neurobiol. 1995, 5:19-27.
    • (1995) Curr. Opin. Neurobiol. , vol.5 , pp. 19-27
    • Calof, A.L.1
  • 9
    • 0028364703 scopus 로고
    • Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus
    • Cameron H.A., Gould E. Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus. Neuroscience 1994, 61:203-209.
    • (1994) Neuroscience , vol.61 , pp. 203-209
    • Cameron, H.A.1    Gould, E.2
  • 11
    • 76849091900 scopus 로고    scopus 로고
    • Reduced adult neurogenesis and altered emotional behaviors in autoimmune-prone B-cell activating factor transgenic mice
    • Crupi R., Cambiaghi M., Spatz L., Hen R., Thorn M., Friedman E., Vita G., Battaglia F. Reduced adult neurogenesis and altered emotional behaviors in autoimmune-prone B-cell activating factor transgenic mice. Biol. Psychiatry 2010, 67:558-566.
    • (2010) Biol. Psychiatry , vol.67 , pp. 558-566
    • Crupi, R.1    Cambiaghi, M.2    Spatz, L.3    Hen, R.4    Thorn, M.5    Friedman, E.6    Vita, G.7    Battaglia, F.8
  • 12
    • 0032752063 scopus 로고    scopus 로고
    • Cellular survival: a play in three Akts
    • Datta S.R., Brunet A., Greenberg M.E. Cellular survival: a play in three Akts. Genes Dev. 1999, 13:2905-2927.
    • (1999) Genes Dev. , vol.13 , pp. 2905-2927
    • Datta, S.R.1    Brunet, A.2    Greenberg, M.E.3
  • 13
    • 0036729758 scopus 로고    scopus 로고
    • Phosphatidylinositol 3 kinase regulates synapse specificity of hippocampal long-term depression
    • Daw M.I., Bortolotto Z.A., Saulle E., Zaman S., Collingridge G.L., Isaac J.T. Phosphatidylinositol 3 kinase regulates synapse specificity of hippocampal long-term depression. Nat. Neurosci. 2002, 5:835-836.
    • (2002) Nat. Neurosci. , vol.5 , pp. 835-836
    • Daw, M.I.1    Bortolotto, Z.A.2    Saulle, E.3    Zaman, S.4    Collingridge, G.L.5    Isaac, J.T.6
  • 14
    • 0035173156 scopus 로고    scopus 로고
    • A subset of lupus anti-DNA antibodies cross-reacts with the NR2 glutamate receptor in systemic lupus erythematosus
    • DeGiorgio L.A., Konstantinov K.N., Lee S.C., Hardin J.A., Volpe B.T., Diamond B. A subset of lupus anti-DNA antibodies cross-reacts with the NR2 glutamate receptor in systemic lupus erythematosus. Nat. Med. 2001, 7:1189-1193.
    • (2001) Nat. Med. , vol.7 , pp. 1189-1193
    • DeGiorgio, L.A.1    Konstantinov, K.N.2    Lee, S.C.3    Hardin, J.A.4    Volpe, B.T.5    Diamond, B.6
  • 15
    • 33847308098 scopus 로고    scopus 로고
    • A role for MAP kinase signaling in behavioral models of depression and antidepressant treatment
    • Duman C.H., Schlesinger L., Kodama M., Russell D.S., Duman R.S. A role for MAP kinase signaling in behavioral models of depression and antidepressant treatment. Biol. Psychiatry 2007, 61:661-670.
    • (2007) Biol. Psychiatry , vol.61 , pp. 661-670
    • Duman, C.H.1    Schlesinger, L.2    Kodama, M.3    Russell, D.S.4    Duman, R.S.5
  • 16
    • 33947372594 scopus 로고    scopus 로고
    • Nerve growth factor promotes survival of new neurons in the adult hippocampus
    • Frielingsdorf H., Simpson D.R., Thal L.J., Pizzo D.P. Nerve growth factor promotes survival of new neurons in the adult hippocampus. Neurobiol. Dis. 2007, 26:47-55.
    • (2007) Neurobiol. Dis. , vol.26 , pp. 47-55
    • Frielingsdorf, H.1    Simpson, D.R.2    Thal, L.J.3    Pizzo, D.P.4
  • 17
  • 18
    • 34547164535 scopus 로고    scopus 로고
    • An overview of the pathogenesis of systemic lupus erythematosus
    • Lippincott Williams & Wilkins, Philadelphia, PA, D.J. Wallace, B.H. Hahn (Eds.)
    • Hahn B.H. An overview of the pathogenesis of systemic lupus erythematosus. Dubois' Lupus Erythematosus 2006, 46-53. Lippincott Williams & Wilkins, Philadelphia, PA. 4th ed. D.J. Wallace, B.H. Hahn (Eds.).
    • (2006) Dubois' Lupus Erythematosus , pp. 46-53
    • Hahn, B.H.1
  • 19
    • 3242788185 scopus 로고    scopus 로고
    • Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis
    • Hao Y., Creson T., Zhang L., Li P., Du F., Yuan P., Gould T.D., Manji H.K., Chen G. Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis. J. Neurosci. 2004, 24:6590-6599.
    • (2004) J. Neurosci. , vol.24 , pp. 6590-6599
    • Hao, Y.1    Creson, T.2    Zhang, L.3    Li, P.4    Du, F.5    Yuan, P.6    Gould, T.D.7    Manji, H.K.8    Chen, G.9
  • 20
    • 0033529638 scopus 로고    scopus 로고
    • Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase
    • Hetman M., Kanning K., Cavanaugh J.E., Xia Z. Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase. J. Biol. Chem. 1999, 274:22569-22580.
    • (1999) J. Biol. Chem. , vol.274 , pp. 22569-22580
    • Hetman, M.1    Kanning, K.2    Cavanaugh, J.E.3    Xia, Z.4
  • 21
    • 34249803812 scopus 로고    scopus 로고
    • Interaction of FGF-2 with IGF-1 and BDNF in stimulating Akt, ERK, and neuronal survival in hippocampal cultures
    • Johnson-Farley N.N., Patel K., Kim D., Cowen D.S. Interaction of FGF-2 with IGF-1 and BDNF in stimulating Akt, ERK, and neuronal survival in hippocampal cultures. Brain Res. 2007, 1154:40-49.
    • (2007) Brain Res. , vol.1154 , pp. 40-49
    • Johnson-Farley, N.N.1    Patel, K.2    Kim, D.3    Cowen, D.S.4
  • 23
    • 0030809453 scopus 로고    scopus 로고
    • Epidermal growth factor and fibroblast growth factor-2 have different effects on neural progenitors in the adult rat brain
    • Kuhn H.G., Winkler J., Kempermann G., Thal L.J., Gage F.H. Epidermal growth factor and fibroblast growth factor-2 have different effects on neural progenitors in the adult rat brain. J. Neurosci. 1997, 17:5820-5829.
    • (1997) J. Neurosci. , vol.17 , pp. 5820-5829
    • Kuhn, H.G.1    Winkler, J.2    Kempermann, G.3    Thal, L.J.4    Gage, F.H.5
  • 25
    • 0012315645 scopus 로고    scopus 로고
    • Neurotrophin secretion: current facts and future prospects
    • Lessmann V., Gottmann K., Malcangio M. Neurotrophin secretion: current facts and future prospects. Prog. Neurobiol. 2003, 69:341-374.
    • (2003) Prog. Neurobiol. , vol.69 , pp. 341-374
    • Lessmann, V.1    Gottmann, K.2    Malcangio, M.3
  • 26
    • 4444381084 scopus 로고    scopus 로고
    • Learning enhances the survival of new neurons beyond the time when the hippocampus is required for memory
    • Leuner B., Mendolia-Loffredo S., Kozorovitskiy Y., Samburg D., Gould E., Shors T.J. Learning enhances the survival of new neurons beyond the time when the hippocampus is required for memory. J. Neurosci. 2004, 24:7477-7481.
    • (2004) J. Neurosci. , vol.24 , pp. 7477-7481
    • Leuner, B.1    Mendolia-Loffredo, S.2    Kozorovitskiy, Y.3    Samburg, D.4    Gould, E.5    Shors, T.J.6
  • 27
    • 21644484449 scopus 로고    scopus 로고
    • A peptide based on the complementarity determining region 1 of a human monoclonal autoantibody ameliorates spontaneous and induced lupus manifestations in correlation with cytokine immunomodulation
    • Luger D., Dayan M., Zinger H., Liu J.P., Mozes E. A peptide based on the complementarity determining region 1 of a human monoclonal autoantibody ameliorates spontaneous and induced lupus manifestations in correlation with cytokine immunomodulation. J. Clin. Immunol. 2004, 24:579-590.
    • (2004) J. Clin. Immunol. , vol.24 , pp. 579-590
    • Luger, D.1    Dayan, M.2    Zinger, H.3    Liu, J.P.4    Mozes, E.5
  • 29
    • 16544378081 scopus 로고    scopus 로고
    • The BAFF/APRIL system: an important player in systemic rheumatic diseases
    • Mackay F., Sierro F., Grey S.T., Gordon T.P. The BAFF/APRIL system: an important player in systemic rheumatic diseases. Curr. Dir. Autoimmun. 2005, 8:243-265.
    • (2005) Curr. Dir. Autoimmun. , vol.8 , pp. 243-265
    • Mackay, F.1    Sierro, F.2    Grey, S.T.3    Gordon, T.P.4
  • 30
    • 33751032081 scopus 로고    scopus 로고
    • Decreased nerve growth factor levels in hyperthyroid Graves' ophthalmopathy highlighting the role of neuroprotective factor in autoimmune thyroid diseases
    • Molnár I., Bokk A. Decreased nerve growth factor levels in hyperthyroid Graves' ophthalmopathy highlighting the role of neuroprotective factor in autoimmune thyroid diseases. Cytokine 2006, 35:109-114.
    • (2006) Cytokine , vol.35 , pp. 109-114
    • Molnár, I.1    Bokk, A.2
  • 31
    • 0345189366 scopus 로고    scopus 로고
    • Inflammatory blockade restores adult hippocampal neurogenesis
    • Monje M.L., Toda H., Palmer T.D. Inflammatory blockade restores adult hippocampal neurogenesis. Science 2003, 302:1760-1765.
    • (2003) Science , vol.302 , pp. 1760-1765
    • Monje, M.L.1    Toda, H.2    Palmer, T.D.3
  • 32
    • 21344443488 scopus 로고    scopus 로고
    • T- and B-cell abnormalities in systemic lupus erythematosus
    • Nagy G., Koncz A., Perl A. T- and B-cell abnormalities in systemic lupus erythematosus. Crit. Rev. Immunol. 2005, 25:123-140.
    • (2005) Crit. Rev. Immunol. , vol.25 , pp. 123-140
    • Nagy, G.1    Koncz, A.2    Perl, A.3
  • 33
    • 63749129584 scopus 로고    scopus 로고
    • B-cell activating factor (BAFF) plays a role in the mechanism of action of a tolerogenic peptide that ameliorates lupus
    • Parameswaran R., Ben David H., Sharabi A., Zinger H., Mozes E. B-cell activating factor (BAFF) plays a role in the mechanism of action of a tolerogenic peptide that ameliorates lupus. Clin. Immunol. 2009, 131:223-232.
    • (2009) Clin. Immunol. , vol.131 , pp. 223-232
    • Parameswaran, R.1    Ben David, H.2    Sharabi, A.3    Zinger, H.4    Mozes, E.5
  • 34
    • 0035234670 scopus 로고    scopus 로고
    • Neurotrophins as synaptic modulators
    • Poo M.M. Neurotrophins as synaptic modulators. Nat. Rev. Neurosci. 2001, 2:24-32.
    • (2001) Nat. Rev. Neurosci. , vol.2 , pp. 24-32
    • Poo, M.M.1
  • 35
    • 29344448889 scopus 로고    scopus 로고
    • Amelioration of SLE-like manifestations in (NZBxNZW)F1 mice following treatment with a peptide based on the complementarity determining region 1 of an autoantibody is associated with a down-regulation of apoptosis and of the pro-apoptotic factor JNK kinase
    • Rapoport M.J., Sharabi A., Aharoni D., Bloch O., Zinger H., Dayan M., Mozes E. Amelioration of SLE-like manifestations in (NZBxNZW)F1 mice following treatment with a peptide based on the complementarity determining region 1 of an autoantibody is associated with a down-regulation of apoptosis and of the pro-apoptotic factor JNK kinase. Clin. Immunol. 2005, 117:262-270.
    • (2005) Clin. Immunol. , vol.117 , pp. 262-270
    • Rapoport, M.J.1    Sharabi, A.2    Aharoni, D.3    Bloch, O.4    Zinger, H.5    Dayan, M.6    Mozes, E.7
  • 37
    • 33751206845 scopus 로고    scopus 로고
    • The negative regulators Foxj1 and Foxo3a are up-regulated by a peptide that inhibits systemic lupus erythematosus-associated T cell responses
    • Sela U., Dayan M., Hershkoviz R., Cahalon L., Lider O., Mozes E. The negative regulators Foxj1 and Foxo3a are up-regulated by a peptide that inhibits systemic lupus erythematosus-associated T cell responses. Eur. J. Immunol. 2006, 36:2971-2980.
    • (2006) Eur. J. Immunol. , vol.36 , pp. 2971-2980
    • Sela, U.1    Dayan, M.2    Hershkoviz, R.3    Cahalon, L.4    Lider, O.5    Mozes, E.6
  • 38
    • 68249153387 scopus 로고    scopus 로고
    • The role of dendritic cells in the mechanism of action of a peptide that ameliorates lupus in murine models
    • Sela U., Sharabi A., Dayan M., Hershkoviz R., Mozes E. The role of dendritic cells in the mechanism of action of a peptide that ameliorates lupus in murine models. Immunology 2009, 128:e395-e405.
    • (2009) Immunology , vol.128
    • Sela, U.1    Sharabi, A.2    Dayan, M.3    Hershkoviz, R.4    Mozes, E.5
  • 39
    • 51549118939 scopus 로고    scopus 로고
    • The suppression of murine lupus by a tolerogenic peptide involves foxp3-expressing CD8 cells that are required for the optimal induction and function of foxp3-expressing CD4 cells
    • Sharabi A., Mozes E. The suppression of murine lupus by a tolerogenic peptide involves foxp3-expressing CD8 cells that are required for the optimal induction and function of foxp3-expressing CD4 cells. J. Immunol. 2008, 181:3243-3251.
    • (2008) J. Immunol. , vol.181 , pp. 3243-3251
    • Sharabi, A.1    Mozes, E.2
  • 40
    • 33745019520 scopus 로고    scopus 로고
    • A peptide based on the complementarity-determining region 1 of an autoantibody ameliorates lupus by up-regulating CD4+ CD25+ cells and TGF-beta
    • Sharabi A., Zinger H., Zborowsky M., Sthoeger Z.M., Mozes E. A peptide based on the complementarity-determining region 1 of an autoantibody ameliorates lupus by up-regulating CD4+ CD25+ cells and TGF-beta. Proc. Natl Acad. Sci. USA 2006, 103:8810-8815.
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 8810-8815
    • Sharabi, A.1    Zinger, H.2    Zborowsky, M.3    Sthoeger, Z.M.4    Mozes, E.5
  • 41
    • 38449119975 scopus 로고    scopus 로고
    • The role of apoptosis in the ameliorating effects of a CDR1-based peptide on lupus manifestations in a mouse model
    • Sharabi A., Luger D., Ben-David H., Dayan M., Zinger H., Mozes E. The role of apoptosis in the ameliorating effects of a CDR1-based peptide on lupus manifestations in a mouse model. J. Immunol. 2007, 179:4979-4987.
    • (2007) J. Immunol. , vol.179 , pp. 4979-4987
    • Sharabi, A.1    Luger, D.2    Ben-David, H.3    Dayan, M.4    Zinger, H.5    Mozes, E.6
  • 42
    • 70349158575 scopus 로고    scopus 로고
    • Disturbed distribution of proliferative brain cells during lupus-like disease
    • Stanojcic M., Burstyn-Cohen T., Nashi N., Lemke G., Sakic B. Disturbed distribution of proliferative brain cells during lupus-like disease. Brain Behav. Immun. 2009, 23:1003-1013.
    • (2009) Brain Behav. Immun. , vol.23 , pp. 1003-1013
    • Stanojcic, M.1    Burstyn-Cohen, T.2    Nashi, N.3    Lemke, G.4    Sakic, B.5
  • 43
    • 0037320314 scopus 로고    scopus 로고
    • Modulation of autoreactive responses of peripheral blood lymphocytes of patients with systemic lupus erythematosus by peptides based on human and murine anti-DNA autoantibodies
    • Sthoeger Z.M., Dayan M., Tcherniack A., Green L., Toledo S., Segal R., Elkayam O., Mozes E. Modulation of autoreactive responses of peripheral blood lymphocytes of patients with systemic lupus erythematosus by peptides based on human and murine anti-DNA autoantibodies. Clin. Exp. Immunol. 2003, 131:385-392.
    • (2003) Clin. Exp. Immunol. , vol.131 , pp. 385-392
    • Sthoeger, Z.M.1    Dayan, M.2    Tcherniack, A.3    Green, L.4    Toledo, S.5    Segal, R.6    Elkayam, O.7    Mozes, E.8
  • 44
    • 34848866530 scopus 로고    scopus 로고
    • Hypoxia/reoxygenation stimulates proliferation through PKC-dependent activation of ERK and Akt in mouse neural progenitor cells
    • Sung S.M., Jung D.S., Kwon C.H., Park J.Y., Kang S.K., Kim Y.K. Hypoxia/reoxygenation stimulates proliferation through PKC-dependent activation of ERK and Akt in mouse neural progenitor cells. Neurochem. Res. 2007, 32:1932-1939.
    • (2007) Neurochem. Res. , vol.32 , pp. 1932-1939
    • Sung, S.M.1    Jung, D.S.2    Kwon, C.H.3    Park, J.Y.4    Kang, S.K.5    Kim, Y.K.6
  • 45
    • 27344439321 scopus 로고    scopus 로고
    • Novel brain reactive autoantibodies: prevalence in systemic lupus erythematosus and association with psychoses and seizures
    • Tin S.K., Xu Q., Thumboo J., Lee L.Y., Tse C., Fong K.Y. Novel brain reactive autoantibodies: prevalence in systemic lupus erythematosus and association with psychoses and seizures. J. Neuroimmunol. 2005, 169:153-160.
    • (2005) J. Neuroimmunol. , vol.169 , pp. 153-160
    • Tin, S.K.1    Xu, Q.2    Thumboo, J.3    Lee, L.Y.4    Tse, C.5    Fong, K.Y.6
  • 46
    • 1642382623 scopus 로고    scopus 로고
    • The potential pathogenetic link between peripheral immune activation and the central innate immune response in neuropsychiatric systemic lupus erythematosus
    • Tomita M., Khan R.L., Blehm B.H., Santoro T.J. The potential pathogenetic link between peripheral immune activation and the central innate immune response in neuropsychiatric systemic lupus erythematosus. Med. Hypotheses 2004, 62:325-335.
    • (2004) Med. Hypotheses , vol.62 , pp. 325-335
    • Tomita, M.1    Khan, R.L.2    Blehm, B.H.3    Santoro, T.J.4
  • 47
    • 0032905515 scopus 로고    scopus 로고
    • Regulation of the hypothalamic-pituitary-adrenal axis by cytokines: actions and mechanisms of action
    • Turnbull A.V., Rivier C.L. Regulation of the hypothalamic-pituitary-adrenal axis by cytokines: actions and mechanisms of action. Physiol. Rev. 1999, 79:1-71.
    • (1999) Physiol. Rev. , vol.79 , pp. 1-71
    • Turnbull, A.V.1    Rivier, C.L.2
  • 48
    • 0037079993 scopus 로고    scopus 로고
    • Reduced hippocampal neurogenesis in adult transgenic mice with chronic astrocytic production of interleukin-6
    • Vallières L., Campbell I.L., Gage F.H., Sawchenko P.E. Reduced hippocampal neurogenesis in adult transgenic mice with chronic astrocytic production of interleukin-6. J. Neurosci. 2002, 22:486-492.
    • (2002) J. Neurosci. , vol.22 , pp. 486-492
    • Vallières, L.1    Campbell, I.L.2    Gage, F.H.3    Sawchenko, P.E.4
  • 49
    • 0025799004 scopus 로고
    • Diagnosis and pathogenesis of CNS lupus
    • van Dam A.P. Diagnosis and pathogenesis of CNS lupus. Rheumatol. Int. 1991, 11:1-11.
    • (1991) Rheumatol. Int. , vol.11 , pp. 1-11
    • van Dam, A.P.1
  • 50
    • 0028939618 scopus 로고
    • The pathogenic human monoclonal anti-DNA that induces experimental systemic lupus erythematosus in mice is encoded by a VH4 gene segment
    • Waisman A., Shoenfeld Y., Blank M., Ruiz P.J., Mozes E. The pathogenic human monoclonal anti-DNA that induces experimental systemic lupus erythematosus in mice is encoded by a VH4 gene segment. Int. Immunol. 1995, 7:689-696.
    • (1995) Int. Immunol. , vol.7 , pp. 689-696
    • Waisman, A.1    Shoenfeld, Y.2    Blank, M.3    Ruiz, P.J.4    Mozes, E.5
  • 51
    • 34047106679 scopus 로고    scopus 로고
    • Autoantibodies involved in neuropsychiatric SLE and antiphospholipid syndrome
    • Zandman-Goddard G., Chapman J., Shoenfeld Y. Autoantibodies involved in neuropsychiatric SLE and antiphospholipid syndrome. Semin. Arthritis Rheum. 2007, 36:297-315.
    • (2007) Semin. Arthritis Rheum. , vol.36 , pp. 297-315
    • Zandman-Goddard, G.1    Chapman, J.2    Shoenfeld, Y.3


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