Impact of fatty acid status on immune function of children in low-income countries

Maternal and Child Nutrition

Volumn 7, Issue SUPPL. 2, 2011, Pages 89-98

  Prentice, Andrew M ^a,b   van der Merwe, Liandré ^a,b  

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

^b MEDICAL RESEARCH COUNCIL LABORATORIES   (Gambia)

Author keywords

Children; Enteropathy; Fatty acid; Growth; Immunity; Low income countries; PUFA

Indexed keywords

DOCOSAHEXAENOIC ACID; FATTY ACID; ICOSAPENTAENOIC ACID; LINOLEIC ACID; LONG CHAIN FATTY ACID; LONG CHAIN POLYUNSATURATED FATTY ACID; MATERNAL ANTIBODY; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; POLYUNSATURATED FATTY ACID; UNCLASSIFIED DRUG;

ADAPTIVE IMMUNITY; ADIPOCYTE; ADIPOSE TISSUE; ANTICOAGULATION; ASTHMA; BIRTH WEIGHT; BODY GROWTH; BREAST FEEDING; BREAST MILK; CELL FUNCTION; CROHN DISEASE; DENDRITIC CELL; DEVELOPING COUNTRY; DIET SUPPLEMENTATION; DOSE RESPONSE; DRUG MEGADOSE; DRUG TREATMENT FAILURE; ENTERITIS; ENTEROPATHY; ESSENTIAL FATTY ACID DEFICIENCY; FAT INTAKE; GAMBIA; HUMAN; HYGIENE; IMMUNOMODULATION; IMMUNOSTIMULATION; IMMUNOTOXICITY; INFANT; INFANT MORTALITY; INNATE IMMUNITY; LIPID PEROXIDATION; LIPID STORAGE; LOWEST INCOME GROUP; LYMPHOCYTE; META ANALYSIS (TOPIC); NUTRITIONAL STATUS; PAKISTAN; PATIENT COMPLIANCE; PREGNANCY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; RHEUMATOID ARTHRITIS; RISK REDUCTION; RURAL AREA; SAMPLE SIZE; SIDE EFFECT; TREATMENT OUTCOME; ULCERATIVE COLITIS;

ARTHRITIS, RHEUMATOID; ASTHMA; BREAST FEEDING; DEVELOPING COUNTRIES; DIETARY SUPPLEMENTS; FATTY ACIDS, UNSATURATED; GAMBIA; HUMANS; IMMUNITY; INFANT; INFANT NUTRITIONAL PHYSIOLOGICAL PHENOMENA; INFLAMMATORY BOWEL DISEASES; META-ANALYSIS AS TOPIC; POVERTY; RANDOMIZED CONTROLLED TRIALS AS TOPIC;

ANIMALIA;

EID: 79952210957     PISSN: 17408695     EISSN: 17408709     Source Type: Journal    
DOI: 10.1111/j.1740-8709.2011.00313.x     Document Type: Review

References (51)

1. Black R.E., Allen L.H., Bhutta Z.A., Caulfield L.E., de Onis M., Ezzati M., Mathers C., Rivera J., for the Maternal and Child Undernutrition Study Group. (2008) Maternal and child undernutrition: global and regional exposures and health consequences. Lancet 371, 243-60.
2. Calder P.C. (2006) n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases. American Journal of Clinical Nutrition 83 (6 Suppl.), 1505S-1519S.
3. Calder P.C. (2008) The relationship between the fatty acid composition of immune cells and their function. Prostaglandins, Leukotrienes, and Essential Fatty Acids 79, 101-108.
4. Calder P.C. (2009) Fatty acids and immune function: relevance to inflammatory bowel diseases. International Reviews of Immunology 28, 506-534.
5. Calder P.C. (2010) Does early exposure to long chain polyunsaturated fatty acids provide immune benefits? Journal of Pediatrics 156, 869-871.
6. Calder P.C., Albers R., Antoine J.M., Blum S., Bourdet-Sicard R., Ferns G.A. etal. (2009) Inflammatory disease processes and interactions with nutrition. British Journal of Nutrition 101 (Suppl. 1), S1-S45.
7. Campbell D.I., McPhail G., Lunn P.G., Elia M. & Jeffries D.J. (2004) Intestinal inflammation measured by fecal neopterin in Gambian children with enteropathy: association with growth failure, Giardia lamblia, and intestinal permeability. Journal of Pediatric Gastroenterology and Nutrition 39, 153-157.
8. Campbell D.I., Murch S.H., Elia M., Sullivan P.B., Sanyang M.S., Jobarteh B. etal. (2003) Chronic T cell-mediated enteropathy in rural west African children: relationship with nutritional status and small bowel function. Pediatric Research 54, 306-311.
9. Fan Y.Y., McMurray D.N., Ly L.H. & Chapkin R.S. (2003) Dietary (n-3) polyunsaturated fatty acids remodel mouse T-cell lipid rafts. Journal of Nutrition 133, 1913-1920.
10. FAO (1994) Fats and oils in human nutrition: report of a joint expert consultation, FAO Food and Nutrition Paper No. 57. Food & Agriculture Organisation: Rome.
11. Galli C. & Calder P.C. (2009) Effects of fat and fatty acid intake on inflammatory and immune responses: a critical review. Annals of Nutrition and Metabolism 55, 123-139.
12. Ganapathy S. (2009) Long chain polyunsaturated fatty acids and immunity in infants. Indian Pediatrics 46, 785-790.
13. German J.B. (2011) Dietary lipids from an evolutionary perspective: sources, structures and functions. Maternal and Child Nutrition 7 (Suppl. 2), 2-16.
14. Glaser C., Lattka E., Rzehak P., Steer C. & Koletzko B. (2011) Genetic variation in polyunsaturated fatty acid metabolism and its potential relevance for human development and health. Maternal and Child Nutrition 7 (Suppl. 2), 27-40.
15. Goto R., Mascie-Taylor C.G. & Lunn P.G. (2009) Impact of intestinal permeability, inflammation status and parasitic infections on infant growth faltering in rural Bangladesh. British Journal of Nutrition 101, 1509-1516.
16. Gottrand F. (2008) Long-chain polyunsaturated fatty acids influence the immune system of infants. Journal of Nutrition 138, 1807S-1812S.
17. Grimble R.F. (2001) Nutritional modulation of immune function. Proceedings of the Nutrition Society 60, 389-397.
18. Harbige L.S. (2003) Fatty acids, the immune response, and autoimmunity: a question of n-6 essentiality and the balance between n-6 and n-3. Lipids 38, 323-341.
19. Harbige L.S. & Fisher B.A. (2001) Dietary fatty acid modulation of mucosally-induced tolerogenic immune responses. Proceedings of the Nutrition Society 60, 449-456.
20. Horejsí V. (2003) The roles of membrane microdomains (rafts) in T cell activation. Immunological Reviews 191, 148-164.
21. Horvath A., Koletzko B. & Szajewska H. (2007) Effect of supplementation of women in high-risk pregnancies with long-chain polyunsaturated fatty acids on pregnancy outcomes and growth measures at birth: a meta-analysis of randomized controlled trials. British Journal of Nutrition 98, 253-259.
22. Hughes D.A., Pinder A.C., Piper Z., Johnson I.T. & Lund E.K. (1996) Fish oil supplementation inhibits the expression of major histocompatibility complex class II molecules and adhesion molecules on human monocytes. American Journal of Clinical Nutrition 63, 267-272.
23. Katagiri Y.U., Kiyokawa N. & Fujimoto J. (2001) A role for lipid rafts in immune cell signaling. Microbiol Immunol 45, 1-8.
24. Lauritzen L. & Carlson S.E. (2011) Maternal fatty acid status during pregnancy and lactation and relation to newborn and infant status. Maternal and Child Nutrition 7 (Suppl. 2), 41-58.
25. Leite M.S., Pacheco P., Gomes R.N., Guedes A.T., Castro-Faria-Neto H.C., Bozza P.T. & Koatz V.L. (2005) Mechanisms of increased survival after lipopolysaccharide-induced endotoxic shock in mice consuming olive oil-enriched diet. Shock 23, 173-8.
26. Lunn P.G., Northrop-Clewes C.A. & Downes R.M. (1991) Intestinal permeability, mucosal injury, and growth faltering in Gambian infants. Lancet 338, 907-910.
27. Makrides M., Collins C.T. & Gibson R.A. (2011) Impact of fatty acid status on growth and neurobehavioural development in humans. Maternal and Child Nutrition 7 (Suppl. 2), 80-88.
28. Makrides M., Gibson R.A., Udell T., Ried K. & International LCPUFA Investigators (2005) Supplementation of infant formula with long-chain polyunsaturated fatty acids does not influence the growth of term infants. American Journal of Clinical Nutrition 81, 1094-1101.
29. Mattacks C.A., Sadler D. & Pond C.M. (2004) Site-specific differences in fatty acid composition of dendritic cells and associated adipose tissue in popliteal depot, mesentery, and omentum and their modulation by chronic inflammation and dietary lipids. Lymphatic Research and Biology 2, 107-129.
30. Michaelsen K.F., Dewey K.G., Perez-Exposito A.B., Nurhasan M., Lauritzen L. & Roos N. (2011) Food sources and intake of n-6 and n-3 fatty acids in low-income countries with emphasis on infants, young children (6-24 months), and pregnant and lactating women. Maternal and Child Nutrition 7 (Suppl. 2), 124-139.
31. van der Merwe L. (2009) Long-chain omega-3 polyunsaturated fatty acids in relation to gut integrity, growth, and cognitive development of rural African children. PhD Thesis, University of London.
32. Pond C.M. (2005) Adipose tissue and the immune system. Prostaglandins, Leukotrienes, and Essential Fatty Acids 73, 17-30.
33. Prentice A.M. & Paul A.A. (2000) Fat and energy needs of children in developing countries. American Journal of Clinical Nutrition 72 (5 Suppl.), 1253S-1265S.
34. Raviv S. & Smith L.J. (2010) Diet and asthma. Current Opinion in Pulmonary Medicine 16, 71-76.
35. Razzaq T.M., Ozegbe P., Jury E.C., Sembi P., Blackwell N.M. & Kabouridis P.S. (2004) Regulation of T-cell receptor signalling by membrane microdomains. Immunology 113, 413-426.
36. Roig-Pérez S., Cortadellas N., Moretó M. & Ferrer R. (2010) Intracellular mechanisms involved in docosahexaenoic acid-induced increases in tight junction permeability in caco-2 cell monolayers. Journal of Nutrition 140, 1557-1563.
37. Rosenfeld E., Beyerlein A., Hadders-Algra M., Kennedy K., Singhal A., Fewtrell M. etal. (2009) IPD meta-analysis shows no effect of LC-PUFA supplementation on infant growth at 18 months. Acta Paediatrica 98, 91-97.
38. Sanderson P., MacPherson G.G., Jenkins C.H. & Calder P.C. (1997) Dietary fish oil diminishes the antigen presentation activity of rat dendritic cells. Journal of Leukocyte Biology 62, 771-777.
39. Serhan C.N., Arita M., Hong S. & Gotlinger K. (2004) Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their endogenous aspirin-triggered epimers. Lipids 39, 1125-1132.
40. Shaikh S.R. & Edidin M. (2007) Immunosuppressive effects of polyunsaturated fatty acids on antigen presentation by human leukocyte antigen class I molecules. Journal of Lipid Research 48, 127-138.
41. Simmer K., Patole S.K. & Rao S.C. (2008a) Longchain polyunsaturated fatty acid supplementation in infants born at term. Cochrane Database of Systematic Reviews, CD000376.
42. Simmer K., Schulzke S.M. & Patole S. (2008b) Longchain polyunsaturated fatty acid supplementation in preterm infants. Cochrane Database of Systematic Reviews, CD000375.
43. Smit E.N., Muskiet F.A. & Boersma E.R. (2004) The possible role of essential fatty acids in the pathophysiology of malnutrition: a review. Prostaglandins, Leukotrienes, and Essential Fatty Acids 71, 241-250.
44. Smit E.N., Oelen E.A., Seerat E., Boersma E.R. & Muskiet F.A. (2000) Fish oil supplementation improves docosahexaenoic acid status of malnourished infants. Archives of Disease in Childhood 82, 366-369.
45. Stulnig T.M., Berger M., Sigmund T., Raederstorff D., Stockinger H. & Waldhäusl W. (1998) Polyunsaturated fatty acids inhibit T cell signal transduction by modification of detergent-insoluble membrane domains. Journal of Cell Biology 143, 637-644.
46. Stulnig T.M., Huber J., Leitinger N., Imre E.M., Angelisova P., Nowotny P. etal. (2001) Polyunsaturated eicosapentaenoic acid displaces proteins from membrane rafts by altering raft lipid composition. Journal of Biological Chemistry 276, 37335-37340.
47. Sullivan P.B. (2002) Studies of the small intestine in persistent diarrhea and malnutrition: the Gambian experience. Journal of Pediatric Gastroenterology and Nutrition 34 (Suppl. 1), S11-S13.
48. Tilley S.L., Coffman T.M. & Koller B.H. (2001) Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes. Journal of Clinical Investigation 108, 15-23.
49. Vachier I., Chanez P., Bonnans C., Godard P., Bousquet J. & Chavis C. (2002) Endogenous anti-inflammatory mediators from arachidonate in human neutrophils. Biochemical and Biophysical Research Communications 290, 219-224.
50. Weatherill A.R., Lee J.Y., Zhao L., Lemay D.G., Youn H.S. & Hwang D.H. (2005) Saturated and polyunsaturated fatty acids reciprocally modulate dendritic cell functions mediated through TLR4. Journal of Immunology 174, 5390-5397.
51. Yaqoob P. & Calder P.C. (2007) Fatty acids and immune function: new insights into mechanisms. British Journal of Nutrition 98 (Suppl. 1), S41-S45.