IPD meta-analysis shows no effect of LC-PUFA supplementation on infant growth at 18 months

Acta Paediatrica, International Journal of Paediatrics

Volumn 98, Issue 1, 2009, Pages 91-97

  Rosenfeld, Eva ^a   Beyerlein, Andreas ^a   Hadders Algra, Mijna ^b   Kennedy, Katherine ^c   Singhal, Atul ^c   Fewtrell, Mary ^c   Lucas, Alan ^c   Koletzko, Berthold ^d   Von Kries, Rüdiger ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

18 months; Growth; IPD meta analysis; LC PUFA

Indexed keywords

ARACHIDONIC ACID; DOCOSAHEXAENOIC ACID; LONG CHAIN FATTY ACID; POLYUNSATURATED FATTY ACID;

ANTHROPOMETRY; ARTICLE; ARTIFICIAL MILK; BIRTH WEIGHT; BODY HEIGHT; BODY MASS; BODY WEIGHT; CHILD GROWTH; CHILD NUTRITION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DIET SUPPLEMENTATION; FEMALE; GESTATIONAL AGE; HEAD CIRCUMFERENCE; HUMAN; MAJOR CLINICAL STUDY; MALE; MATERNAL AGE; META ANALYSIS; MULTIVARIATE ANALYSIS; PREMATURITY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SMOKING; SYSTEMATIC REVIEW; TERM BIRTH; THIRD TRIMESTER PREGNANCY;

ANTHROPOMETRY; ARACHIDONIC ACID; DIETARY SUPPLEMENTS; DOCOSAHEXAENOIC ACIDS; FATTY ACIDS, UNSATURATED; FEMALE; HUMANS; INFANT; INFANT FORMULA; MALE; MULTIVARIATE ANALYSIS; NUTRITIONAL STATUS;

EID: 57449084153     PISSN: 08035253     EISSN: 16512227     Source Type: Journal    
DOI: 10.1111/j.1651-2227.2008.00988.x     Document Type: Article

References (28)

1. Uauy R, Castillo C. Lipid requirements of infants: implications for nutrient composition of fortified complementary foods. J Nutr 2003 133 : 2962S 72S.
2. Simmer K, Patole S, Rao S. Longchain polyunsaturated fatty acid supplementation in infants born at term. Cochrane Database Syst Rev 2008 CD000376.
3. Simmer K, Schulzke S, Patole S. Longchain polyunsaturated fatty acid supplementation in preterm infants. Cochrane Database Syst Rev 2008 CD000375.
4. Koletzko B, Lien E, Agostoni C, Böhles H, Campoy C, Cetin I, et al. The roles of long-chain polyunsaturated fatty acids in pregnancy, lactation and infancy: review of current knowledge and consensus recommendations. J Perinat Med 2008 36 : 5 14.
5. Lucas A, Stafford M, Morley R, Abbott R, Stephenson T, MacFadyen U, et al. Efficacy and safety of long-chain polyunsaturated fatty acid supplementation of infant-formula milk: a randomised trial. Lancet 1999 354 : 1948 54.
6. Uauy RD, Birch DG, Birch EE, Tyson JE, Hoffman DR. Effect of dietary omega-3 fatty acids on retinal function of very-low-birth-weight neonates. Pediatr Res 1990 28 : 485 92.
7. Makrides M, Neumann M, Simmer K, Pater J, Gibson R. Are long-chain polyunsaturated fatty acids essential nutrients in infancy? Lancet 1995 345 : 1463 68.
8. Clandinin MT, Van Aerde JE, Parrott A, Field CJ, Euler AR, Lien EL. Assessment of the efficacious dose of arachidonic and docosahexaenoic acids in preterm infant formulas: fatty acid composition of erythrocyte membrane lipids. Pediatr Res 1997 42 : 819 25.
9. Auestad N, Montalto MB, Hall RT, Fitzgerald KM, Wheeler RE, Connor WE, et al., for the Ross Pediatric Lipid Study. Visual acuity, erythrocyte fatty acid composition, and growth in term infants fed formulas with long chain polyunsaturated fatty acids for one year. Pediatr Res 1997 41 : 1 10.
10. Willatts P, Forsyth JS, DiModugno MK, Varma S, Colvin M. Effect of long-chain polyunsaturated fatty acids in infant formula on problem solving at 10 months of age. Lancet 1998 352 : 688 91.
11. Vanderhoof J, Gross S, Hegyi T. A multicenter long-term safety and efficacy trial of preterm formula supplemented with long-chain polyunsaturated fatty acids. J Pediatr Gastroenterol Nutr 200 31 : 121 7.
12. Makrides M, Neumann MA, Simmer K, Gibson RA. A critical appraisal of the role of dietary long-chain polyunsaturated fatty acids on neural indices of term infants: a randomized, controlled trial. Pediatrics 2000 105 : 32 8.
13. Birch EE, Garfield S, Hoffman DR, Uauy R, Birch DG. A randomized controlled trial of early dietary supply of long-chain polyunsaturated fatty acids and mental development in term infants. Dev Med Child Neurol 2000 42 : 174 81.
14. O'Connor DL, Hall R, Adamkin D, Auestad N, Castillo M, Connor WE, et al. Growth and development in preterm infants fed long-chain polyunsaturated fatty acids: a prospective, randomized controlled trial. Pediatrics 2001 108 : 359 71.
15. Makrides M, Gibson RA, Udell T, Ried K. Supplementation of infant formula with long-chain polyunsaturated fatty acids does not influence the growth of term infants. Am J Clin Nutr 2005 81 : 1094 101.
16. Innis SM, Adamkin DH, Hall RT, Kalhan SC, Lair C, Lim M, et al. Docosahexaenoic acid and arachidonic acid enhance growth with no adverse effects in preterm infants fed formula. J Pediatr 2002 140 : 547 54.
17. Hansen J, Schade D, Harris C, Merkel K, Adamkin D, Hall R, et al. Docosahexaenoic acid plus arachidonic acid enhance preterm infant growth. Prostaglandins Leukot Essent Fatty Acids 1997 57 : 198.
18. Fewtrell MS, Morley R, Abbott RA, Singhal A, Isaacs EB, Stephenson T, et al. Double-blind, randomized trial of long-chain polyunsaturated fatty acid supplementation in formula fed to preterm infants. Pediatrics 2002 110 : 73 82.
19. Carlson SE, Cooke RJ, Werkman SH, Tolley EA. First year growth of preterm infants fed standard compared to marine oil n-3 supplemented formula. Lipids 1992 27 : 901 7.
20. Carlson SE, Werkman SH, Tolley EA. Effect of long-chain n-3 fatty acid supplementation on visual acuity and growth of preterm infants with and without bronchopulmonary dysplasia. Am J Clin Nutr 1996 63 : 687 97.
21. Bouwstra H, Dijck-Brouwer DA, Wildeman JA, Tjoonk HM, van der Heide JC, Boersma ER, et al. Long-chain polyunsaturated fatty acids have a positive effect on the quality of general movements of healthy term infants. Am J Clin Nutr 2003 78 : 313 18.
22. Fewtrell MS, Abbott RA, Kennedy K, Singhal A, Morley R, Caine E, et al. Randomized, double-blind trial of long-chain polyunsaturated fatty acid supplementation with fish oil and borage oil in preterm infants. J Pediatr 2004 144 : 471 9.
23. Egger M, Smith GD, Altman DG, editors. Systematic reviews in health care: meta-analysis in context. London, BMJ Books, 2001.
24. Stewart LA, Parmar MK. Meta-analysis of the literature or of individual patient data: is there a difference? Lancet 1993 341 : 418 22.
25. Lee AP, Chernausek SD, Hokken-Koelega AC, Czernichow P. International small for gestational age advisory board consensus development conference statement: management of short children born small for gestational age. Pediatrics 2003 111 : 1253 61.
26. Cole TJ, Green PJ. Smoothing reference centile curves: the LMS method and penalized likelihood. Stat Med 1992 11 : 1305 19.
27. Cole TJ, Freeman JV, Preece MA. British 1990 growth reference centiles for weight, height, body mass index and head circumference fitted by maximum penalized likelihood. Stat Med 1998 17 : 407 29.
28. Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med 2002 21 : 1539 58.