Long chain polyunsaturated fatty acids and immunity in infants

Indian Pediatrics

Volumn 46, Issue 9, 2009, Pages 785-790

  Ganapathy, Sridhar ^a,b  

^a Lion Tarachand Bapa Hospital   (India)

^b 14 276 Tata Co op Building   (India)

Author keywords

Immunity; Infants nutrition; Polyunsaturated fatty acids

Indexed keywords

ARACHIDONIC ACID; DOCOSAHEXAENOIC ACID; GAMMA LINOLENIC ACID; ICOSAPENTAENOIC ACID; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; LINOLEIC ACID; LONG CHAIN POLYUNSATURATED FATTY ACID; PLACEBO; POLYUNSATURATED FATTY ACID; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTIFICIAL MILK; ATOPY; BRAIN GROWTH; BREAST MILK; CHILD DEVELOPMENT; CLINICAL TRIAL; CYTOKINE PRODUCTION; DERMATITIS; HUMAN; IMMUNE SYSTEM; IMMUNITY; IMMUNOMODULATION; INFANT DISEASE; INFANT NUTRITION; INTESTINE FLORA; LACTATION; LOW BIRTH WEIGHT; NUTRIENT; PREGNANCY; REVIEW; THROMBOCYTOPENIA;

FATTY ACIDS, UNSATURATED; HUMANS; IMMUNE SYSTEM; INFANT; INFANT, LOW BIRTH WEIGHT; INFANT, NEWBORN; MILK, HUMAN;

EID: 70349600726     PISSN: 00196061     EISSN: 00196061     Source Type: Journal    
DOI: None     Document Type: Review

References (26)

1. Koletzko B, Mrotzek M, Eng B, Bremer HJ. Fatty acid composition of human milk in Germany. Am J Clin Nutr 1988; 47: 954-959. (Pubitemid 18154385)
2. Fleith M, Clandinin MT. Dietary PUFA for preterm and term infants: review of clinical studies. Crit Rev Food Sci Nutr 2005; 45: 205-229. (Pubitemid 41657357)
3. th ed. London: Taylor & Francis Inc; 1999.
4. Wara DW, Barrett DJ. Cell-mediated immunity in the newborn: clinical aspects. Pediatrics 1979; 64: 822-828. (Pubitemid 10195725)
5. Hassan J, Reen DJ. Reduced primary antigenspecific T-cell precursor frequencies in neonates is associated with deficient interleukin-2 production. Immunology 1996; 87: 604-608. (Pubitemid 26116470)
6. Chheda S, Palkowetz KH, Garofalo R, Rassin DK, Goldman AS. Decreased interleukin-10 production by neonatal monocytes and T cells: Relationship to decreased production and expression of tumor necrosis factor-alpha and its receptors. Pediatr Res 1996; 40: 475-483. (Pubitemid 26282584)
7. Lewis DB, Prickett KS, Larsen A, Grabstein K, Weaver M, Wilson CB. Restricted production of interleukin 4 by activated human T cells. Proc Natl Acad Sci USA 2005; 85: 9743-9747.
8. Lilic D, Cant AJ, Abinun M, Calvert JE, Spickett GP. Cytokine production differs in children and adults. Pediatr Res 1997; 42: 237-240. (Pubitemid 27311347)
9. Calder PC, Krauss-Etschmann S, de Jong EC, Dupont C, Frick JS, Frokiaer H, et al. Early nutrition and immunity: progress and perspectives. Br J Nutr 2006; 96: 774-790. (Pubitemid 46470203)
10. Newburg DS. Innate immunity and human milk. J Nutr 2005; 135: 1308-1312.
11. Heird WC. The role of polyunsaturated fatty acids in term and preterm infants and breastfeeding mothers. Pediatr Clin North Am 2001; 48: 173-188. (Pubitemid 32193134)
12. Prentice A. Regional variations in the composition of human milk. In: Jensens RG, editor. Handbook of Milk Composition. New York: Academic Press; 1995. p. 115-221.
13. Calder PC. Polyunsaturated fatty acids, inflammation, and immunity. Lipids 2001; 36: 1007-1024. (Pubitemid 33065203)
14. Neonate and Infant Nutrition and Immunity. Available from: URL: http://www.arkinternational.co.uk/Infant%20nutrition.pdf. Accessed April 21, 2009.
15. Field CJ, Johnson IR, Schley PD. Nutrients and their role in host resistance to infection. J Leukoc Biol 2002; 71:16-32.
16. Koletzko B, Larqué E, Demmelmair H. Placental transfer of long-chain polyunsaturated fatty acids (LC-PUFA). J Perinat Med 2007; 35 (Suppl 1): S5-S11. (Pubitemid 46279663)
17. Helland IB, Saugstad OD, Smith L, Saarem K, Solvoll K, Ganes T, et al. Similar effects on infants of n-3 and n-6 fatty acids supplementation to pregnant and lactating women. Pediatrics 2001; 108: 1-10.
18. Foote KD, Mckinnon MJ, Innis SM. Effect of early introduction of formula vs fat-free parenteral nutrition on essential fatty acid status of preterm infants. Am J Clin Nutr 1991; 54: 93-97.
19. Chatrath R, Saili A, Jain M, Dutta AK. Immune Status of full-term small-for-gestational age neonates in India. J Trop Pediatr 1997; 43: 345-348. (Pubitemid 28040674)
20. Schanler RJ. Suitability of human milk for the low birthweight infant. Clin Perinatol 1995; 22: 207-222.
21. + cell and deficient Interleukin-10 production by formula fed infants, compared with human-fed, is corrected with supplementation of long-chain polyunsaturated fatty acids. J Pediatr Gastroenterol Nutr 2000; 31: 291-299.
22. Damsgaard CT, Lauritzen L, Kjær TMR, Holm PMI, Fruekilde MB, Michaelsen KF, et al. Fish oil supplementation modulates immune function in healthy infants. J Nutr 2007; 137: 1031-1036. (Pubitemid 46596905)
23. Denburg JA, Hatfield HM, Cyr MM, Hayes L, Holt PG, Sehmi R, et al. Fish oil supplementation in pregnancy modifies neonatal progenitors at birth in infants at risk of atopy. Pediatr Res 2005; 57: 276-281. (Pubitemid 40165608)
24. Duchén K, Yu G, Björkstén B. Atopic sensitization during the first year of life in relation to long chain polyunsaturated fatty acid levels in human milk. Pediatr Res 1998: 44: 478-484. (Pubitemid 28447331)
25. Liet JM, Piloquet H, Marchini JS, Maugère P, Bobin C, Rozé JC, et al. Leucine metabolism in preterm infants receiving parenteral nutrition with medium-chain compared with long-chain triacylglycerol emulsions. Am J Clin Nutr 1999; 69: 539-543. (Pubitemid 29104578)
26. Koletzko B, Baker S, Cleghorn G, Neto UF, Gopalan S, Hernell O, et al. Global standard for the composition of infant formula: Recommendations of an ESPGHAN coordinated International Expert Group. J Pediatr Gastroenterol Nutr 2005; 41: 584-599. (Pubitemid 41579668)