Synthesis and hydrolytic evaluation of acid-labile imine-linked cytotoxic isatin model systems

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 5, 2011, Pages 1771-1778

  Matesic, Lidia ^a   Locke, Julie M ^a   Vine, Kara L ^a   Ranson, Marie ^a   Bremner, John B ^a   Skropeta, Danielle ^a  

^a UNIVERSITY OF WOLLONGONG   (Australia)

Author keywords

Acid catalysed; Hydrolysis; Imines; Isatin; Prodrugs

Indexed keywords

ACID; BENZOIC ACID; CARBONYL DERIVATIVE; CYTOTOXIC AGENT; CYTOTOXIN; IMINE; ISATIN DERIVATIVE; PHENYLACETIC ACID; PHENYLPROPIONIC ACID DERIVATIVE; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE;

ARTICLE; CATALYSIS; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; HYDROLYSIS; MOLECULAR STABILITY; PH;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; IMINES; ISATIN; LYMPHOMA; MODELS, BIOLOGICAL; MOLECULAR STRUCTURE;

EID: 79952195584     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2011.01.015     Document Type: Article

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