Acidic hydrolysis of N-ethoxybenzylimidazoles (NEBIs): Potential applications as pH-sensitive linkers for drug delivery

Bioconjugate Chemistry

Volumn 18, Issue 2, 2007, Pages 293-296

  Kong, Seong Deok ^a   Luong, Alice ^a   Manorek, Gerald ^b   Howell, Stephen B ^b   Yang, Jerry ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONTROLLED DRUG DELIVERY; CYTOTOXICITY; DISEASES; HYDROLYSIS; PH EFFECTS; PHYSIOLOGY; PLANTS (BOTANY); TARGETED DRUG DELIVERY;

ACIDIC HYDROLYSIS; CANCER DRUG DELIVERIES; DOXORUBICIN; DRUG-DELIVERY SYSTEMS; IMIDAZOL; KINETIC ANALYSIS; N-LINKED; PH SENSITIVE; PHYSIOLOGICAL PH; RATE OF HYDROLYSIS;

PH SENSORS;

ANTINEOPLASTIC AGENT; DOXORUBICIN; IMIDAZOLE DERIVATIVE; N (4 FORMYLBENZOYL)DOXORUBICIN; N ETHOXYBENZYLIMIDAZOLE; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; CANCER CELL; CONCENTRATION RESPONSE; CONTROLLED DRUG RELEASE; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; HALF LIFE TIME; HUMAN; HUMAN CELL; HYDROLYSIS; KINETICS; OVARY CANCER; PH; PROTON NUCLEAR MAGNETIC RESONANCE; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

EID: 33947621538     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc060224s     Document Type: Article

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