Schiff bases derived from p-aminobenzyl alcohol as trigger groups for pH-dependent prodrug activation

Tetrahedron Letters

Volumn 51, Issue 33, 2010, Pages 4371-4374

  Müller, Ivonne A ^a   Kratz, Felix ^a   Jung, Manfred ^b   Warnecke, André ^a  

^a TUMOR BIOLOGY CENTER   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Acid sensitive; Benzyl elimination; Prodrug activation; Schiff base

Indexed keywords

4 AMINOBENZYL; 4 AMINOBENZYLOXYCARBONYL; 7 ISOCYANATO 4 METHYLCOUMARIN; BENZALDEHYDE; BENZALDEHYDE DERIVATIVE; BENZYL DERIVATIVE; CARBONYL DERIVATIVE; COUMARIN DERIVATIVE; IMINE; PRODRUG; SCHIFF BASE; UNCLASSIFIED DRUG;

ACIDITY; ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; DRUG ACTIVATION; ELIMINATION REACTION; HYDROLYSIS; PH MEASUREMENT; SYNTHESIS; TEMPERATURE MEASUREMENT;

EID: 77955424900     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2010.06.055     Document Type: Article

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