Biological activity and ligand binding mode to the progesterone receptor of A-homo analogues of progesterone

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 5, 2011, Pages 1683-1691

  Alvarez, Lautaro D ^a,b   Dansey, María V ^a   Martí, Marcelo A ^a   Bertucci, Paola Y ^b   Di Chenna, Pablo H ^a   Pecci, Adalí ^a,b   Burton, Gerardo ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b INSTITUTO DE FISIOLOGÍA   (Argentina)

Author keywords

A Homo pregnane; Molecular dynamics; Progestagen; Progesterone receptor

Indexed keywords

5 PREGNENE 3,20 DIONE; 5 PREGNENE 4,20 DIONE; COMPLEMENTARY DNA; GESTAGEN; LIGAND; MINERALOCORTICOID RECEPTOR; PROGESTERONE; PROGESTERONE RECEPTOR; PROTEIN BCL XL; RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOLOGICAL ACTIVITY; BREAST CANCER; CANCER CELL; CELL STRAIN COS1; CRYSTAL STRUCTURE; HORMONE RECEPTOR INTERACTION; HYDROGEN BOND; LIGAND BINDING; MOLECULAR DYNAMICS; MOLECULAR MODEL; NONHUMAN; QUANTUM MECHANICS; STRUCTURE ACTIVITY RELATION;

ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; LIGANDS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; PREGNANES; PROGESTERONE; RECEPTORS, PROGESTERONE;

EID: 79952184243     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2011.01.033     Document Type: Article

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