Progesterone binding to mineralocorticoid receptors: In vitro and in vivo studies

American Journal of Physiology - Endocrinology and Metabolism

Volumn 270, Issue 4 33-4, 1996, Pages

  Myles, K ^a   Funder, J W ^a  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

Author keywords

hippocampus; steroids and behavior

Indexed keywords

ALDOSTERONE; CORTICOSTERONE; HYDROCORTISONE; MIFEPRISTONE; MINERALOCORTICOID; MINERALOCORTICOID RECEPTOR; PROGESTERONE; TRANSCORTIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COLON; CYTOSOL; FEMALE; GUINEA PIG; HEART; HIPPOCAMPUS; HORMONE BINDING; IN VITRO STUDY; IN VIVO STUDY; KIDNEY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; RECEPTOR OCCUPANCY;

EID: 0029972850     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.1996.270.4.e601     Document Type: Article

References (27)

1. τ-dependent isoform of 11β-hydroxysteroid dehydrogenase: cloning and characterization of cDNA from sheep kidney. J. Biol. Chem. 269: 25959-25962, 1994.
2. Albiston, A., V. Obeyesekere, R. Smith, and Z. Krozowski. Cloning and tissue distribution of the human 11-beta hydroxysteroid dehydrogenase type II enzyme. Mol. Cell. Endocrinol. 105: R11-R17, 1994.
3. Arriza, J. L., C. Weinberger, T. Glaser, B. L. Handelin, D. E. Houseman, and R. M. Evans. Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptors. Science Wash. DC 237: 268-275, 1987.
4. Bradford, M. M. A rapid and sensitive method for determining microgram quantities of protein utilizing the principle of protein dye binding. Anal. Biochem. 72: 248-253, 1976.
5. Bruning, P. F., K. M. Jonker, and A. W. Boerema-Baan. Absorption of steroid hormones by plastic tubing. J. Steroid Biochem. 14: 553-555, 1981.
6. Cole, T. Cloning of the mouse 11β-hydroxysteroid dehydrogenase type 2 gene: tissue specific expression and localization in distal convoluted tubules and collecting ducts of the kidney. Endocrinology 136: 4693-4696, 1995.
7. Edwards, C. R. W., P. M. Stewart, D. Burt, M. A. McIntyre, E. R. de Kloet, L. Brett, W. S. Sutano, and C. Monder. Localization of 11β-hydroxysteroid dehydrogenase-tissue specific protector of the mineralocorticoid receptor. Lancet 2: 986-989, 1988.
8. Ferrari, P., R. E. Smith, J. W. Funder, and Z. S. Krozowski. Substrate and inhibitor specificity of the cloned human 11β-hydroxysteroid dehydrogenase type 2 isoform. Am. J. Physiol. In press.
9. Funder, J. W. A la recherche du temps perdu. In: Aldosterone: Fundamental Aspects. Montrouge, France: Libbey Eurotext, 1991, p. 77-83.
10. Funder, J. W. Corticosteroid hormones and signal specificity. In: Corticosteroid Receptors: Studies on the Mechanism, Function and Neurotoxicity of Corticosteroid Action. New York: Ann. NY Acad. Sci., 1994, p. 1-7.
11. Funder, J. W., P. T. Pearce, R. Smith, and A. I. Smith. Mineralocorticoid action: target-tissue specificity is enzyme, not receptor, mediated. Science Wash. DC 242: 583-585, 1988.
12. Krozowski, Z. S., and J. W. Funder. Renal mineralocorticoid receptors and hippocampal corticosterone binding species have identical intrinsic steroid specificity. Proc. Natl. Acad. Sci. USA 80: 6056-6060, 1983.
13. Krozowski, Z., J. A. Maguire, A. N. Stein Oakley, J. Dowling, R. E. Smith, and R. K. Andrews. Immunohistochemical localization of the 11β-hydroxysteroid dehydrogenase type II enzyme in human kidney and placenta. J. Clin. Endocrinol. Metab. In press.
14. Laidlaw, J. C., J. L. Ruse, and A. G. Gornall. The influence of estrogen and progesterone on aldosterone excretion. J. Clin. Endocrinol. Metab. 22: 161-171, 1962.
15. Landau, R. L., D. M. Bergenstal, K. Lugibihl, and M. E. Kascht. The metabolic effects of progesterone in man. J. Clin. Endocrinol. Metab. 15: 1194-1215, 1955.
16. Landau, R. L., and K. Lugibihl. Inhibition of the sodium-retaining influence of aldosterone by progesterone. J. Clin. Endocrinol. Metab. 18: 1237-1245, 1958.
17. MacDonald, R. G., and J. A. Cidlowski. Alterations in specificity of the glucocorticoid receptor with temperature in rat splenic lymphocytes. J. Steroid Biochem. 10: 21-29, 1979.
18. Myles, K., and J. W. Funder. Type I (mineralocorticoid) receptors in the guinea pig. Am. J. Physiol. 267 (Endocrinol. Metab. 30): E268-E272, 1994.
19. Naray-Fejes-Toth, A., and G. Fejes-Toth. Expression cloning of the aldosterone target cell-specific 11β-hydroxysteroid dehydrogenase from rabbit collecting duct cells. Endocrinology 136: 2579-2586, 1995.
20. Oparil, S., E. N. Ehrlich, and M. D. Lindheimer. Effect of progesterone on renal sodium handling in man: relation to aldosterone excretion and plasma renin activity. Clin. Sci. Mol. Med. 49: 139-147, 1975.
21. Reul, J. M. H. M., and E. R. de Kloet. Two receptor systems for corticosterone in rat brain: microdistribution and differential occupation. Endocrinology 117: 2505-2511, 1985.
22. Roland, B. R., Z. S. Krozowski, and J. W. Funder. GR, MR, 11β-HSD1 and 11β-HSD2 expression in rat brain and kidney: in situ studies. Mol. Cell. Endocrinol. 111: R1-R7, 1995.
23. Rupprecht, R., J. M. H. M. Reul, B. van Steensel, D. Spengler, M. Soder, B. Berning, F. Holsboer, and K. Damm. Pharmacological and functional characterization of human mineralocorticoid and glucocorticoid receptor ligands. Eur. J. Pharmacol. 247: 145-154, 1993.
24. Wambach, G., and J. R. Higgins. Antimineralocorticoid action of progesterone in the rat: correlation of the effect on electrolyte excretion and interaction with renal mineralocorticoid receptors. Endocrinology 102: 1686-1693, 1978.
25. Wambach, G., and J. R. Higgins. Antihypertensive effect of progesterone in rats with mineralocorticoid-induced hypertension. Am. J. Physiol. 236 (Endocrinol. Metab. Gastrointest. Physiol. 5): E366-E370, 1979.
26. Young, M. J., and J. W. Funder. Mechanisms of aldosterone-salt-induced cardiac fibrosis: localization studies. Proc. 21st Ann. Int. Aldosterone Conf. Washington DC 1995, p. 2-3.
27. Zhou, M.-Y., E. P. Gomez-Sanchez, D. L. Cox, D. Cosby, and C. E. Gomez-Sanchez. Cloning, expression, and tissue distribution of the rat nicotinamide adenine dimicleotide-dependent 11β-hydroxysteroid dehydrogenase. Endocrinology 136: 3729-3734, 1995.