Effect of electron-withdrawing substituents on the epoxide ring: An experimental and theoretical electron density analysis of a series of epoxide derivatives

Journal of Organic Chemistry

Volumn 76, Issue 5, 2011, Pages 1305-1318

  Grabowsky, Simon ^a   Schirmeister, Tanja ^b   Paulmann, Carsten ^c   Pfeuffer, Thomas ^b   Luger, Peter ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c UNIVERSITY OF HAMBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ATOMIC CHARGE; BUILDING BLOCKES; C-C BONDS; CRITICAL POINTS; DRUG DESIGN; ELECTRON DENSITIES; ELECTRON DENSITY ANALYSIS; ELECTRON-WITHDRAWING SUBSTITUENTS; ELECTRONWITHDRAWING; ELECTROSTATIC CONTRIBUTIONS; INTERMOLECULAR INTERACTIONS; LATTICE ENERGIES; MOLECULAR SURFACES; NUCLEOPHILIC RING-OPENING; ORGANIC SYNTHESIS; PROTEASE INHIBITOR; SOURCE FUNCTIONS; WORK FOCUS;

CARRIER CONCENTRATION; DENSITY FUNCTIONAL THEORY; DRUG INTERACTIONS; ELECTRON DENSITY MEASUREMENT; FUNCTIONAL GROUPS;

ELECTRONS;

CARBON; EPOXIDE;

ARTICLE; ATOM; CHEMICAL BOND; CHEMICAL INTERACTION; ELECTRON; NUCLEOPHILICITY; RING OPENING; SUBSTITUTION REACTION; SYNTHESIS;

CRYSTALLOGRAPHY, X-RAY; ELECTRONS; EPOXY COMPOUNDS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; QUANTUM THEORY; STEREOISOMERISM;

EID: 79952175154     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo102125n     Document Type: Article

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