메뉴 건너뛰기




Volumn 30, Issue 175, 2011, Pages 75-81

Cyclooxygenases inhibitors and other compounds with antiinflamatory potential in osteoarthrosis - Part I;Inhibitory cyklooksygenaz i inne zwiqzki o potencjale przeciwzapalnym w chorobie zwyrodnieniowej stawów (osteoartrozie - OA) - czȩść i

Author keywords

Cyclooxygenases; Dual cyclooxygenases and 5 lipooxygenase inhibitors; Leucotriens; Licofelone; Nonselective and selective cyclooxygenases inhibitors; Osteoarthrosis; Prostaglandins

Indexed keywords

ANTIINFLAMMATORY AGENT; LICOFELONE; LIPOXYGENASE INHIBITOR; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN SYNTHASE INHIBITOR; PYRROLE DERIVATIVE;

EID: 79952144183     PISSN: 14269686     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (1)

References (28)
  • 1
    • 23544472526 scopus 로고    scopus 로고
    • Licofelone-a 5-LOX, COX-1 and COX- Inhibitor-is as effective as naproxen and has improved Gl tolerability in patients with osteoarthritis
    • Bias P., Buchner A.: Licofelone-a 5-LOX, COX-1 and COX- inhibitor-is as effective as naproxen and has improved Gl tolerability in patients with osteoarthritis. Arthritis Rheum., 2003, 48 (supl.), S72.
    • (2003) Arthritis Rheum. , vol.48 , Issue.SUPL
    • Bias, P.1    Buchner, A.2
  • 2
    • 2342496237 scopus 로고    scopus 로고
    • The gastrointestinal tolerability of the LOX/COX inhibitor, licofelone, is similar to placebo and superior to naproxen therapy in healthy volunteers: Results from a randomized, controlled trial
    • Bias P., Buchner A., Klesser B. i wsp.: The gastrointestinal tolerability of the LOX/COX inhibitor, licofelone, is similar to placebo and superior to naproxen therapy in healthy volunteers: results from a randomized, controlled trial. Am J Gastroenterol., 2004, 99, 611-618.
    • (2004) Am J Gastroenterol. , vol.99 , pp. 611-618
    • Bias, P.1    Buchner, A.2    Klesser, B.3
  • 3
    • 1042270689 scopus 로고    scopus 로고
    • Licofelone, an inhibitor of COX-1, COX2, and 5-LOX, is as effective as naproxen and shows improved safety during 12 weeks treatment in patients with osteoarthritis of the knee
    • Blanco F.J., Buchner A., Bias P.: Licofelone, an inhibitor of COX-1, COX2, and 5-LOX, is as effective as naproxen and shows improved safety during 12 weeks treatment in patients with osteoarthritis of the knee. Ann Rheum Dis., 2003, 62, 261.
    • (2003) Ann Rheum Dis. , vol.62 , pp. 261
    • Blanco, F.J.1    Buchner, A.2    Bias, P.3
  • 4
    • 0034707105 scopus 로고    scopus 로고
    • Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis
    • VIGOR Study Group
    • Bombardier C., Laine L., Reicin A. i wsp.: Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group. N. Engl. J. Med., 2000, 343, 1520.
    • (2000) N. Engl. J. Med. , vol.343 , pp. 1520
    • Bombardier, C.1    Laine, L.2    Reicin, A.3
  • 5
    • 1542297649 scopus 로고    scopus 로고
    • Selective cyclooxygenase-2 inhibitors: Similarities and differences
    • Brune K., Hinz B.: Selective cyclooxygenase-2 inhibitors: similarities and differences. Scand. J. Rheumatol. 2004, 33, 1-6.
    • (2004) Scand. J. Rheumatol. , vol.33 , pp. 1-6
    • Brune, K.1    Hinz, B.2
  • 6
    • 38149026239 scopus 로고    scopus 로고
    • Co nowego w niesterydowych lekach przeciwzapalnych?
    • Dzielska-Olczak M.: Co nowego w niesterydowych lekach przeciwzapalnych? Pol.Merk. Lek., 2007, 138, 454-458.
    • (2007) Pol.Merk. Lek. , vol.138 , pp. 454-458
    • Dzielska-Olczak, M.1
  • 7
    • 0038718727 scopus 로고    scopus 로고
    • Relative contribution of acetylated cyclo-oxygenase (COX)-2 and 5-lipooxygenase (LOX) in regulating gastric mucosal integrity and adaptation to aspirin
    • Fiorucci S., Distrutti E., de Lima O.M. i wsp.: Relative contribution of acetylated cyclo-oxygenase (COX)-2 and 5-lipooxygenase (LOX) in regulating gastric mucosal integrity and adaptation to aspirin. FASEB J., 2003, 17, 1171-1173.
    • (2003) FASEB J. , vol.17 , pp. 1171-1173
    • Fiorucci, S.1    Distrutti, E.2    De Lima, O.M.3
  • 8
    • 0032701224 scopus 로고    scopus 로고
    • The cyclooxygenase isoforms: Structural insights into the conversion of arachidonic acid to prostaglandins
    • Garavito R.M., DeWitt D.L.: The cyclooxygenase isoforms: structural insights into the conversion of arachidonic acid to prostaglandins. Biochem. Biophys. Acta., 1999, 1441, 278-287.
    • (1999) Biochem. Biophys. Acta. , vol.1441 , pp. 278-287
    • Garavito, R.M.1    DeWitt, D.L.2
  • 9
    • 78650608368 scopus 로고    scopus 로고
    • Licofelone - Novel analgesic and anti-inflammatory agent for osteoarthritis: An overview
    • Gaur K., Kori M.L., Tyagi L.K. i wsp.: Licofelone - novel analgesic and anti-inflammatory agent for osteoarthritis: An overview. Pharm Chem., 2009, 1, 67-71.
    • (2009) Pharm Chem. , vol.1 , pp. 67-71
    • Gaur, K.1    Kori, M.L.2    Tyagi, L.K.3
  • 10
    • 0034863527 scopus 로고    scopus 로고
    • Dual inhibition of 5-lipoxygenase and cyclooxygenases 1 and 2 by ML 300 reduces joint destruction in adjuvant arthritis
    • Gay R.E., Niedhart M., Pataky F. i wsp.: Dual inhibition of 5-lipoxygenase and cyclooxygenases 1 and 2 by ML 300 reduces joint destruction in adjuvant arthritis. J. Rheumatol., 2001, 28, 2060-2065.
    • (2001) J. Rheumatol. , vol.28 , pp. 2060-2065
    • Gay, R.E.1    Niedhart, M.2    Pataky, F.3
  • 11
    • 0029899186 scopus 로고    scopus 로고
    • A single amino acid difference between cyclooxygenase-1 (COX-1) and -2 (COX-2) reverses the selectivity of COX-2 specific inhibitors
    • Gierse J.K., McDonald, Rangwala SA. i wsp.: A single amino acid difference between cyclooxygenase-1 (COX-1) and -2 (COX-2) reverses the selectivity of COX-2 specific inhibitors. J. Biol. Chem., 1996, 271, 15180-15184.
    • (1996) J. Biol. Chem. , vol.271 , pp. 15180-15184
    • Gierse, J.K.1    McDonald2    Rangwala, S.A.3
  • 12
    • 0029816469 scopus 로고    scopus 로고
    • Effect of lipoxygenase inhibitors and leukotriene antagonists on acute and chronic gastric haemorrhagic mucosal lesions in ulcer models in the rat
    • Gyomber E., Vattay P., Szabo S., Rainsford K.D.: Effect of lipoxygenase inhibitors and leukotriene antagonists on acute and chronic gastric haemorrhagic mucosal lesions in ulcer models in the rat. J Gastroenterol Hepatol., 1996, 11, 922-927.
    • (1996) J Gastroenterol Hepatol. , vol.11 , pp. 922-927
    • Gyomber, E.1    Vattay, P.2    Szabo, S.3    Rainsford, K.D.4
  • 13
    • 38949136999 scopus 로고    scopus 로고
    • Acetaminophen (paracetamol) is a selective cyclooxygenase-2 inhibitor in man
    • Hinz B., Cheremina O., Brune K.: Acetaminophen (paracetamol) is a selective cyclooxygenase-2 inhibitor in man. FASEB J., 2008, 22, 383-390.
    • (2008) FASEB J. , vol.22 , pp. 383-390
    • Hinz, B.1    Cheremina, O.2    Brune, K.3
  • 14
    • 0034757607 scopus 로고    scopus 로고
    • In vivo dual Inhibition of cyclooxygenase and lipoxygenase by ML-3000 reduces the progression of experimental osteoarthritis: Supression of collagenase-1 and interleukin-1 beta synthesis
    • Jovanovic D.V., Fernandes J.C., Martel-Pelletier J. i wsp.: In vivo dual Inhibition of cyclooxygenase and lipoxygenase by ML-3000 reduces the progression of experimental osteoarthritis: supression of collagenase-1 and interleukin-1 beta synthesis. Arthritis Rheum., 2001, 44, 2320-2330.
    • (2001) Arthritis Rheum. , vol.44 , pp. 2320-2330
    • Jovanovic, D.V.1    Fernandes, J.C.2    Martel-Pelletier, J.3
  • 15
    • 0026588059 scopus 로고
    • Prostaglandin endoperoxide synthase gene structure: Identification of the transcriptional start site and 5′-flanking regulatory sequences
    • Kraemer S.A., Meade E.A., DeWitt D.L.: Prostaglandin endoperoxide synthase gene structure: identification of the transcriptional start site and 5′-flanking regulatory sequences. Arch. Biochem. Byophys., 1992, 293, 391-400.
    • (1992) Arch. Biochem. Byophys. , vol.293 , pp. 391-400
    • Kraemer, S.A.1    Meade, E.A.2    DeWitt, D.L.3
  • 16
    • 0030461132 scopus 로고    scopus 로고
    • Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents
    • Kurumbail R.G., Stevens A.M., Gierse J.K. i wsp.: Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents. Nature, 1996, 384, 644-648.
    • (1996) Nature , vol.384 , pp. 644-648
    • Kurumbail, R.G.1    Stevens, A.M.2    Gierse, J.K.3
  • 17
    • 33749339372 scopus 로고    scopus 로고
    • Cardiovascular risk and inhibition of cyclooxygenase: A systematic review of the observational studies of selective and nonselective inhibitors of cyclooxygenase 2
    • McGettigan P., Henry D.: Cardiovascular risk and inhibition of cyclooxygenase: a systematic review of the observational studies of selective and nonselective inhibitors of cyclooxygenase 2. JAMA, 2006, 296, 1633-1644.
    • (2006) JAMA , vol.296 , pp. 1633-1644
    • McGettigan, P.1    Henry, D.2
  • 18
    • 0038147318 scopus 로고    scopus 로고
    • Therapeutic role of dual inhibitors of 5-LOX and COX, selective and non-selective nonsteroidal anti-inflammatory drugs
    • Martel-Pelletier J.M., Lajeunesse D., Rebout P. i wsp.: Therapeutic role of dual inhibitors of 5-LOX and COX, selective and non-selective nonsteroidal anti-inflammatory drugs. Ann. Rheum. Dis., 2003, 62, 501-509.
    • (2003) Ann. Rheum. Dis. , vol.62 , pp. 501-509
    • Martel-Pelletier, J.M.1    Lajeunesse, D.2    Rebout, P.3
  • 19
    • 3242889081 scopus 로고    scopus 로고
    • Lumiracoxib (Prexige): A new selective COX-2 inhibitor
    • Mysler E.: Lumiracoxib (Prexige): a new selective COX-2 inhibitor. Int. J. Clin. Pract., 2004, 58, 606-611.
    • (2004) Int. J. Clin. Pract. , vol.58 , pp. 606-611
    • Mysler, E.1
  • 20
    • 77954697249 scopus 로고    scopus 로고
    • Przeciwzapalne 'prowygaszenlowe' pochodne wielonienasyconych kwasów tluszczowych omega 3i omega 6
    • Nowak J.Z.: Przeciwzapalne 'prowygaszenlowe' pochodne wielonienasyconych kwasów tluszczowych omega 3i omega 6. Postȩpy Hig. Med. Dośw., 2010, 64, 115-132.
    • (2010) Postȩpy Hig. Med. Dośw. , vol.64 , pp. 115-132
    • Nowak, J.Z.1
  • 21
    • 1042270689 scopus 로고    scopus 로고
    • Licofelone, an inhibitor of COX-1, COX-2 and 5-LOX, is as effective as celecoxib and shows improved tolerability during 12 weeks of treatment in patients with OA of the knee
    • Pavelka K., Bias P., Buchner A. i wsp.: Licofelone, an inhibitor of COX-1, COX-2 and 5-LOX, is as effective as celecoxib and shows improved tolerability during 12 weeks of treatment in patients with OA of the knee. Ann. Rheum. Dis., 2003, 62 (supl.1), 261.
    • (2003) Ann. Rheum. Dis. , vol.62 , Issue.SUPL.1 , pp. 261
    • Pavelka, K.1    Bias, P.2    Buchner, A.3
  • 22
    • 69949158726 scopus 로고    scopus 로고
    • Evolution of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): Cyclooxygenase (COX) Inhibition and beyond
    • Praveen Rao P.N., Knaus E.E.: Evolution of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): Cyclooxygenase (COX) Inhibition and Beyond. J. Pharm. Pharmaceut. Sci., 2008, 11, 81-110.
    • (2008) J. Pharm. Pharmaceut. Sci. , vol.11 , pp. 81-110
    • Praveen Rao, P.N.1    Knaus, E.E.2
  • 23
    • 67449128722 scopus 로고    scopus 로고
    • Protective effects of licofelone, a 5-lipoxygenase and cycl-oxygenase inhibitor, versus naproxen on cartilage loss in knee osteoarthritis: A first multicentre clinical trial using quantitative MRI
    • Raynauld J.P., Martel-Pelletier J., Bias P. i wsp.: Protective effects of licofelone, a 5-lipoxygenase and cycl-oxygenase inhibitor, versus naproxen on cartilage loss in knee osteoarthritis: a first multicentre clinical trial using quantitative MRI. Ann. Rheum. Dis., 2009, 68, 938-947.
    • (2009) Ann. Rheum. Dis. , vol.68 , pp. 938-947
    • Raynauld, J.P.1    Martel-Pelletier, J.2    Bias, P.3
  • 24
    • 0034644396 scopus 로고    scopus 로고
    • Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis. The CLASS study: A randomized controlled trial
    • Silverstein F.E., Faich G., Goldstein J.L. i wsp.: Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis. The CLASS study: A randomized controlled trial. JAMA, 2000, 284, 1247.
    • (2000) JAMA , vol.284 , pp. 1247
    • Silverstein, F.E.1    Faich, G.2    Goldstein, J.L.3
  • 25
    • 40549108939 scopus 로고    scopus 로고
    • Licofelone, a dual COX/5-LOX inhibitor, induces apoptosis in HCA-7 colon cancer cells through the mitochondrial pathway independently from its ability to affect the arachidonic acid cascade
    • Tavolari S., Bonafe M., Marini M. i wsp.: Licofelone, a dual COX/5-LOX inhibitor, induces apoptosis in HCA-7 colon cancer cells through the mitochondrial pathway independently from its ability to affect the arachidonic acid cascade. Carcinogenesis, 2008, 29, 371-380.
    • (2008) Carcinogenesis , vol.29 , pp. 371-380
    • Tavolari, S.1    Bonafe, M.2    Marini, M.3
  • 26
    • 0025349874 scopus 로고
    • Effects of leukotrienes on susceptibility of the rat stomach to damage and investigation of the mechanism of action
    • Wallace J.L., McKnight G.W., Keenan C.M. i wsp.: Effects of leukotrienes on susceptibility of the rat stomach to damage and investigation of the mechanism of action. Gastroenterology, 1990, 98, 1178-1186.
    • (1990) Gastroenterology , vol.98 , pp. 1178-1186
    • Wallace, J.L.1    McKnight, G.W.2    Keenan, C.M.3
  • 27
    • 0033594911 scopus 로고    scopus 로고
    • Nonsteroid drug selectivities for cyclooxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: A full in vitro analysis
    • Warner T.D., Giullano F., Vojnovic I.i wsp.: Nonsteroid drug selectivities for cyclooxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis. Proc Natl. Acad. Sci. USA, 1999, 96, 7563-7568.
    • (1999) Proc Natl. Acad. Sci. USA , vol.96 , pp. 7563-7568
    • Warner, T.D.1    Giullano, F.2    Vojnovic, I.3
  • 28
    • 38149029249 scopus 로고    scopus 로고
    • COX-2 selectivity alone does not define the cardiovascular risks associated with non-steroidal anti-infl ammatory drugs
    • Warner T.D., Mitchell J.A.: COX-2 selectivity alone does not define the cardiovascular risks associated with non-steroidal anti-infl ammatory drugs. Lancet, 2008 , 371, 270-273.
    • (2008) Lancet , vol.371 , pp. 270-273
    • Warner, T.D.1    Mitchell, J.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.