The cyclooxygenase isoforms: Structural insights into the conversion of arachidonic acid to prostaglandins

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1441, Issue 2-3, 1999, Pages 278-287

  Garavito, R Michael ^a   Dewitt, David L ^a  

^a Michigan State University   (United States)

Author keywords

Aspirin; Cyclooxygenase; Membrane protein; Prostaglandin biosynthesis

Indexed keywords

5 (4 FLUOROPHENYL) 1 [(4 METHYLSULFONYL)PHENYL] 3 TRIFLUOROMETHYLPYRAZOLE; 5 BROMO 2 (4 FLUOROPHENYL) 3 (4 METHYLSULFONYLPHENYL)THIOPHENE; ACETYLSALICYLIC ACID; CELECOXIB; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2 INHIBITOR; FLURBIPROFEN; IBUPROFEN; ISOENZYME; L 746483; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN SYNTHASE; SC 588; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARACHIDONIC ACID METABOLISM; BINDING SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME STRUCTURE; MEMBRANE BINDING; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN LIPID INTERACTION; REVIEW;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BINDING SITES; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DIMERIZATION; FATTY ACIDS; HUMANS; ISOENZYMES; MEMBRANE PROTEINS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES;

EID: 0032701224     PISSN: 13881981     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1388-1981(99)00147-X     Document Type: Review

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