In vivo dual inhibition of cyclooxygenase and lipoxygenase by ML-3000 reduces the progression of experimental osteoarthritis: Suppression of collagenase 1 and interleukin-1β synthesis

Arthritis and Rheumatism

Volumn 44, Issue 10, 2001, Pages 2320-2330

  Jovanovic, Dragan V ^a   Fernandes, Julio C ^b   Martel Pelletier, Johanne ^c   Jolicoeur, François Cyril ^a   Reboul, Pascal ^a   Laufer, Stefan ^b   Tries, Susanne ^c   Pelletier, Jean Pierre ^a  

^a NOTRE DAME HOSPITAL   (Canada)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c TEVA PHARMACEUTICALS   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

LEUKOTRIENE B4; LICOFELONE; LIPOXYGENASE; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTERIOR CRUCIATE LIGAMENT; ARTICLE; CARTILAGE; CONTROLLED STUDY; DOG; DRUG BLOOD LEVEL; DRUG MECHANISM; ENZYME INHIBITION; HISTOLOGY; IMMUNOHISTOCHEMISTRY; NONHUMAN; OSTEOARTHRITIS; PRIORITY JOURNAL; SYNOVIAL FLUID; SYNOVITIS;

ACETIC ACIDS; ANIMALS; COLLAGENASES; CYCLOOXYGENASE INHIBITORS; DOGS; INTERLEUKIN-1; LIPOXYGENASE; LIPOXYGENASE INHIBITORS; OSTEOARTHRITIS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PYRROLES;

EID: 0034757607     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/1529-0131(200110)44:10<2320::AID-ART394>3.0.CO;2-P     Document Type: Article

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