Ubiquitination-resistant p53 protein transduction therapy facilitates anti-cancer effect on the growth of human malignant glioma cells

FEBS Letters

Volumn 579, Issue 18, 2005, Pages 3965-3969

  Michiue, Hiroyuki ^a   Tomizawa, Kazuhito ^a   Matsushita, Masayuki ^a   Tamiya, Takashi ^b   Lu, Yun Fei ^c   Ichikawa, Tomotsugu ^a   Date, Isao ^a   Matsui, Hideki ^a,c  

^a OKAYAMA UNIVERSITY   (Japan)

^b KAGAWA UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Brain tumor; Gene therapy; p53; Poly arginine; TAT

Indexed keywords

ARGININE; COMPLEMENTARY DNA; LYSINE; MUTANT PROTEIN; PROTEIN MDM2; PROTEIN P53;

AMINO ACID SUBSTITUTION; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFECT; GLIOMA CELL; HUMAN; HUMAN CELL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN PURIFICATION; RAT; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TUMOR GROWTH; UBIQUITINATION;

ADENOVIRIDAE; ANTINEOPLASTIC AGENTS; BLOTTING, WESTERN; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL SURVIVAL; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE THERAPY; GENES, P53; GENES, REPORTER; GLIOMA; HUMANS; IN SITU NICK-END LABELING; MUTAGENESIS, SITE-DIRECTED; PEPTIDES; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; TIME FACTORS; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITIN;

EID: 21844477537     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2005.06.021     Document Type: Article

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