Decreased intake of a liquid diet in nonfood-deprived rats following intra-PVN injections of GLP-1 (7-36) amide

Pharmacology Biochemistry and Behavior

Volumn 58, Issue 3, 1997, Pages 673-677

  McMahon, L R ^a   Wellman, P J ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Feeding; Norepinephrine; Paraventricular nucleus; Peptide

Indexed keywords

GLUCAGON LIKE PEPTIDE 1 [7-36] AMIDE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; FLUID INTAKE; FOOD INTAKE; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; THALAMUS MIDLINE NUCLEUS;

EID: 0030819077     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(97)90017-4     Document Type: Article

References (26)

1. Alvarez E., Roncero I., Chowen J. A., Thorens B., Blazquez E. Expression of the glucagon-like peptide-1 receptor gene in rat brain. J. Neurochem. 66:1996;920-927.
2. Asarian L., Cuomo A. M., Corp E., Hrupka B., Geary N. Glucagon-like peptide-1 (7-36 amide) elicits behavioral satiety in sham feeding rats. Soc. Neurosci. Abstr. 22:1996;16.
3. Cooper S. J. Drugs and hormones. Their effects on ingestion Toates F. M., Rowland N. E. Feeding and drinking, vol. 1. 1987;231-269 Elsevier Science Publishers B.A, New York.
4. Fletcher P. J., Patterson I. A. A comparison of the effects of tryptamine and 5-hydroxytryptamine on feeding following injection into the paraventricular nucleus of the hypothalamus. Pharmacol. Biochem. Behav. 32:1989;907-911.
5. Jin S. L., Han V. K. M., Simmons J. G., Towle A. C., Lauder J. M., Lund P. K. Distribution of glucagon like peptide 1 (GLP-1), glucagon, and glicentin, in the rat brain. An immunocytochemical study J. Comp. Neurol. 271:1988;519-532.
6. Kanse S. M., Kreymann B., Ghatei M. A., Bloom S. R. Identification and characterization of glucagon-like peptide-1 7-36 amide-binding sites in the rat brain and lung. FEBS Lett. 241:1988;209-212.
7. Kreymann B., Ghatei M. A., Burnet P., Williams G., Kanse S., Diani A. R., Bloom S. R. Characterization of glucagon-like peptide-1-(7-36) amide in the hypothalamus. Brain Res. 502:1989;325-331.
8. Leibowitz S. F. Paraventricular nucleus. A primary site mediating adrenergic stimulation of feeding and drinking Pharmacol. Biochem. Behav. 8:1978;163-175.
9. Leibowitz S. F. Hypothalamic paraventricular nucleus. Interaction between α2-noredrenergic system and circulating hormones and nutrients in relation to energy balance Neurosci. Biobehav. Rev. 12:1988;101-109.
10. Leibowitz S. F., Myers R. D. The neurochemistry of ingestion. Chemical stimulation of the brain and in vivo measurement of transmitter release Toates F. M., Rowland N. E. Feeding and drinking, vol. 1. 1987;271-315 Elsevier Science Publishers B.A, New York.
11. Moran T. H., Wohn A., Schwartz G. J., Ladenheim E. E. Fourth ventricular administration of glucagon-like peptide-1. -36 amide (GLP-1) inhibits food intake in rats Soc. Neurosci. Abstr. 22:1996;15.
12. Navarro M., Rodriguez de Foncesa F., Zueco J. A., Gomez R., Blazquez E. Changes in food intake induced by GLP-1. -36 amide in the rat 15th International Diabetes Federation Congress:1994;. Kobe, Japan;
13. Orskov C. Glucagon-like peptide-1, a new hormone of the entero-insular axis. Diabetologia. 35:1992;701-711.
14. Paxinos G., Watson C. The rat brain in stereotaxic coordinates. 2:1986;Academic Press, New York.
15. Roland C. R., Oppenheimer R. L., Chang K., Leibowitz S. F. Hypophysectomy disturbs the noradrenergic feeding system of the paraventricular nucleus. Psychoneuroendocrinology. 10:1985;109-120.
16. Shughrue P. J., Lane M. V., Merchenthaler I. The distribution of glucagon-like peptide-1 receptor (GLP1-R) mRNA in the rat brain. Endocrinology. 137:1996;5159-5162.
17. Smith G. P., Gibbs J. Postprandial satiety. Sprague J. M., Epstein A. N. Progress in psychobiology and physiological psychology, vol. 8. 1979;179-242 Academic Press, New York.
18. Stanley B. G. Neuropeptide Y in multiple hypothalamic sites controls eating behavior, endocrine, and autonomic systems for body energy balance. Colmers W. F., Wahlestedt C. The biology of neuropeptide Y and related peptides. 1993;457-509 Humana Press, Totowa, NJ.
19. Tang-Christensen M., Larsen P. J., Goke R., Fink-Jensen A., Jessop D. S., Moller M., Sheikh S. P. Central administration of GLP-1-(7-36) amide inhibits food and water intake in rats. Am. J. Physiol. 271:1996;R848-R856.
20. Thiele T. E., Van Dijk G., Donahey J. C. K., Campfield L. A., Smith F. J., Bernstein I. L., Woods S. C., Seeley R. J. Central infusion of leptin (OB protein) and GLP-1-(7-36) amide differentially stimulate c-fos expression in rat brain. Soc. Neurosci. Abstr. 15:1996;1411.
21. Turton M. D., O'Shea D., Gunn I., Beak S. A., Edwards C. M. B., Meeran K., Choi S. J., Taylor G. M., Heath M. M., Lambert P. D., Wilding J. P. H., Smith D. M., Ghatei M. A., Herbert J., Bloom S. R. A role for glucagon-like peptide-1 in the central regulation of feeding. Nature. 379:1996;69-72.
22. 2 in the paraventricular nucleus of the hypothalamus increases feeding J. Endocrinol. (Suppl.). 148:1996;P126.
23. Wang Z., Wang R. M., Owji A. A., Smith D. M., Ghatei M. A., Bloom S. R. Glucagon-like peptide-1 is a physiological incretin in rat. J. Clin. Invest. 95:1995;417-421.
24. Weiss G. F., Papadokos P., Knudson K., Leibowitz S. F. Medial hypothalamic serotonin. effects on deprivation and norepinephrine-induced feeding Pharmacol. Biochem. Behav. 25:1986;1223-1230.
25. Wellman P. J., Davies B. T. Suppression of feeding induced by phenylephrine microinjections within the paraventricular hypothalamus in rats. Appetite. 17:1991;121-128.
26. Wellman P. J., Davies B. T., Morien A., McMahon L. R. Modulation of feeding by hypothalamic paraventricular nucleus α1- and α2-adrenergic receptors. Life Sci. 53:1993;669-679.