메뉴 건너뛰기




Volumn 4, Issue 11, 2008, Pages

A PI3-kinase-mediated negative feedback regulates neuronal excitability

Author keywords

[No Author keywords available]

Indexed keywords

METABOTROPIC RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; S6 KINASE; TARGET OF RAPAMYCIN KINASE; TRANSCRIPTION FACTOR FOXO; DROSOPHILA PROTEIN; FORKHEAD TRANSCRIPTION FACTOR; FOXO PROTEIN, DROSOPHILA; GLUTAMIC ACID; PROTEIN TYROSINE KINASE; TORSO PROTEIN, DROSOPHILA; UNCLASSIFIED DRUG;

EID: 57149117828     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000277     Document Type: Article
Times cited : (45)

References (63)
  • 2
    • 0037426916 scopus 로고    scopus 로고
    • Current compensation in neuronal homeostasis
    • Marder E, Prinz AA (2003) Current compensation in neuronal homeostasis. Neuron 37: 2-4.
    • (2003) Neuron , vol.37 , pp. 2-4
    • Marder, E.1    Prinz, A.A.2
  • 3
    • 38349133919 scopus 로고    scopus 로고
    • Activity-dependent phosphorylation of Ser187 is required for SNAP-25-negative modulation of neuronal voltage-gated calcium channels
    • Pozzi D, Condliffe S, Bozzi Y, Chikhladze M, Grumelli C, et al. (2008) Activity-dependent phosphorylation of Ser187 is required for SNAP-25-negative modulation of neuronal voltage-gated calcium channels. Proc Natl Acad Sci U S A 105: 323-328.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 323-328
    • Pozzi, D.1    Condliffe, S.2    Bozzi, Y.3    Chikhladze, M.4    Grumelli, C.5
  • 4
    • 0033360297 scopus 로고    scopus 로고
    • Plasticity in the intrinsic excitability of cortical pyramidal neurons
    • Desai NS, Rutherford LC, Turrigiano GG (1999) Plasticity in the intrinsic excitability of cortical pyramidal neurons. Nat Neurosci 2: 515-520.
    • (1999) Nat Neurosci , vol.2 , pp. 515-520
    • Desai, N.S.1    Rutherford, L.C.2    Turrigiano, G.G.3
  • 6
    • 33745745916 scopus 로고    scopus 로고
    • Role for the subthreshold currents ILeak and IH in the homeostatic control of excitability in neocortical somatostatin-positive inhibitory neurons
    • Gibson JR, Bartley AF, Huber KM (2006) Role for the subthreshold currents ILeak and IH in the homeostatic control of excitability in neocortical somatostatin-positive inhibitory neurons. J Neurophysiol 96: 420-432.
    • (2006) J Neurophysiol , vol.96 , pp. 420-432
    • Gibson, J.R.1    Bartley, A.F.2    Huber, K.M.3
  • 7
    • 0036487193 scopus 로고    scopus 로고
    • Synaptic transmission in nucleus tractus solitarius is depressed by Group II and III but not Group I presynaptic metabotropic glutamate receptors in rats
    • Chen CY, Ling Eh EH, Horowitz JM, Bonham AC (2002) Synaptic transmission in nucleus tractus solitarius is depressed by Group II and III but not Group I presynaptic metabotropic glutamate receptors in rats. J Physiol 538: 773-786.
    • (2002) J Physiol , vol.538 , pp. 773-786
    • Chen, C.Y.1    Ling, E.E.2    Horowitz, J.M.3    Bonham, A.C.4
  • 8
    • 0033758653 scopus 로고    scopus 로고
    • Activity-dependent presynaptic autoinhibition by group II metabotropic glutamate receptors at the perforant path inputs to the dentate gyrus and CA1
    • Kew JN, Ducarre JM, Pflimlin MC, Mutel V, Kemp JA (2001) Activity-dependent presynaptic autoinhibition by group II metabotropic glutamate receptors at the perforant path inputs to the dentate gyrus and CA1. Neuropharmacology 40: 20-27.
    • (2001) Neuropharmacology , vol.40 , pp. 20-27
    • Kew, J.N.1    Ducarre, J.M.2    Pflimlin, M.C.3    Mutel, V.4    Kemp, J.A.5
  • 9
    • 23644440521 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 2 modulates excitatory synaptic transmission in the rat globus pallidus
    • Poisik O, Raju DV, Verreault M, Rodriguez A, Abeniyi OA, et al. (2005) Metabotropic glutamate receptor 2 modulates excitatory synaptic transmission in the rat globus pallidus. Neuropharmacology 49 Suppl 1: 57-69.
    • (2005) Neuropharmacology , vol.49 , Issue.SUPPL. 1 , pp. 57-69
    • Poisik, O.1    Raju, D.V.2    Verreault, M.3    Rodriguez, A.4    Abeniyi, O.A.5
  • 10
    • 0031036195 scopus 로고    scopus 로고
    • Use-dependent increases in glutamate concentration activate presynaptic metabotropic glutamate receptors
    • Scanziani M, Salin PA, Vogt KE, Malenka RC, Nicoll RA (1997) Use-dependent increases in glutamate concentration activate presynaptic metabotropic glutamate receptors. Nature 385: 630-634.
    • (1997) Nature , vol.385 , pp. 630-634
    • Scanziani, M.1    Salin, P.A.2    Vogt, K.E.3    Malenka, R.C.4    Nicoll, R.A.5
  • 11
    • 0034811597 scopus 로고    scopus 로고
    • Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system
    • Schoepp DD (2001) Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system. J Pharmacol Exp Ther 299: 12-20.
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 12-20
    • Schoepp, D.D.1
  • 12
    • 34948858402 scopus 로고    scopus 로고
    • Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: A randomized Phase 2 clinical trial
    • Patil ST, Zhang L, Martenyi F, Lowe SL, Jackson KA, et al. (2007) Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial. Nat Med 13: 1102-1107.
    • (2007) Nat Med , vol.13 , pp. 1102-1107
    • Patil, S.T.1    Zhang, L.2    Martenyi, F.3    Lowe, S.L.4    Jackson, K.A.5
  • 13
    • 14044258729 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors as novel targets for anxiety and stress disorders
    • Swanson CJ, Bures M, Johnson MP, Linden AM, Monn JA, et al. (2005) Metabotropic glutamate receptors as novel targets for anxiety and stress disorders. Nat Rev Drug Discov 4: 131-144.
    • (2005) Nat Rev Drug Discov , vol.4 , pp. 131-144
    • Swanson, C.J.1    Bures, M.2    Johnson, M.P.3    Linden, A.M.4    Monn, J.A.5
  • 14
    • 33747151426 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors as a strategic target for the treatment of epilepsy
    • Alexander GM, Godwin DW (2006) Metabotropic glutamate receptors as a strategic target for the treatment of epilepsy. Epilepsy Res 71: 1-22.
    • (2006) Epilepsy Res , vol.71 , pp. 1-22
    • Alexander, G.M.1    Godwin, D.W.2
  • 15
    • 0032907608 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors: Electrophysiological properties and role in plasticity
    • Anwyl R (1999) Metabotropic glutamate receptors: electrophysiological properties and role in plasticity. Brain Res Brain Res Rev 29: 83-120.
    • (1999) Brain Res Brain Res Rev , vol.29 , pp. 83-120
    • Anwyl, R.1
  • 16
    • 5644264828 scopus 로고    scopus 로고
    • The Drosophila metabotropic glutamate receptor DmGluRA regulates activity-dependent synaptic facilitation and fine synaptic morphology
    • Bogdanik L, Mohrmann R, Ramaekers A, Bockaert J, Grau Y, et al. (2004) The Drosophila metabotropic glutamate receptor DmGluRA regulates activity-dependent synaptic facilitation and fine synaptic morphology. J Neurosci 24: 9105-9116.
    • (2004) J Neurosci , vol.24 , pp. 9105-9116
    • Bogdanik, L.1    Mohrmann, R.2    Ramaekers, A.3    Bockaert, J.4    Grau, Y.5
  • 17
    • 0006941874 scopus 로고
    • Genetic dissection of short-term and long-term facilitation at the Drosophila neuromuscular junction
    • Jan YN, Jan LY (1978) Genetic dissection of short-term and long-term facilitation at the Drosophila neuromuscular junction. Proc Natl Acad Sci U S A 75: 515-519.
    • (1978) Proc Natl Acad Sci U S A , vol.75 , pp. 515-519
    • Jan, Y.N.1    Jan, L.Y.2
  • 18
    • 0024709832 scopus 로고
    • Altered synaptic transmission in Drosophila hyperkinetic mutants
    • Stern M, Ganetzky B (1989) Altered synaptic transmission in Drosophila hyperkinetic mutants. J Neurogenet 5: 215-228.
    • (1989) J Neurogenet , vol.5 , pp. 215-228
    • Stern, M.1    Ganetzky, B.2
  • 19
    • 0025021560 scopus 로고
    • Dosage effects of a Drosophila sodium channel gene on behavior and axonal excitability
    • Stern M, Kreber R, Ganetzky B (1990) Dosage effects of a Drosophila sodium channel gene on behavior and axonal excitability. Genetics 124: 133-143.
    • (1990) Genetics , vol.124 , pp. 133-143
    • Stern, M.1    Kreber, R.2    Ganetzky, B.3
  • 20
    • 0029129194 scopus 로고
    • A potassium channel beta subunit related to the aldo-keto reductase superfamily is encoded by the Drosophila hyperkinetic locus
    • Chouinard SW, Wilson GF, Schlimgen AK, Ganetzky B (1995) A potassium channel beta subunit related to the aldo-keto reductase superfamily is encoded by the Drosophila hyperkinetic locus. Proc Natl Acad Sci U S A 92: 6763-6767.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 6763-6767
    • Chouinard, S.W.1    Wilson, G.F.2    Schlimgen, A.K.3    Ganetzky, B.4
  • 21
    • 0024976602 scopus 로고
    • Molecular analysis of the para locus, a sodium channel gene in Drosophila
    • Loughney K, Kreber R, Ganetzky B (1989) Molecular analysis of the para locus, a sodium channel gene in Drosophila. Cell 58: 1143-1154.
    • (1989) Cell , vol.58 , pp. 1143-1154
    • Loughney, K.1    Kreber, R.2    Ganetzky, B.3
  • 22
    • 0026110318 scopus 로고
    • Nerve terminal excitability and neuromuscular transmission in T(X;Y)V7 and Shaker mutants of Drosophila melanogaster
    • Mallart A, Angaut-Petit D, Bourret-Poulain C, Ferrus A (1991) Nerve terminal excitability and neuromuscular transmission in T(X;Y)V7 and Shaker mutants of Drosophila melanogaster. J Neurogenet 7: 75-84.
    • (1991) J Neurogenet , vol.7 , pp. 75-84
    • Mallart, A.1    Angaut-Petit, D.2    Bourret-Poulain, C.3    Ferrus, A.4
  • 23
    • 5444249309 scopus 로고    scopus 로고
    • Regulation of neuronal excitability through pumilio-dependent control of a sodium channel gene
    • Mee CJ, Pym EC, Moffat KG, Baines RA (2004) Regulation of neuronal excitability through pumilio-dependent control of a sodium channel gene. J Neurosci 24: 8695-8703.
    • (2004) J Neurosci , vol.24 , pp. 8695-8703
    • Mee, C.J.1    Pym, E.C.2    Moffat, K.G.3    Baines, R.A.4
  • 24
    • 0036021390 scopus 로고    scopus 로고
    • The Drosophila melanogaster translational repressor pumilio regulates neuronal excitability
    • Schweers BA, Walters KJ, Stern M (2002) The Drosophila melanogaster translational repressor pumilio regulates neuronal excitability. Genetics 161: 1177-1185.
    • (2002) Genetics , vol.161 , pp. 1177-1185
    • Schweers, B.A.1    Walters, K.J.2    Stern, M.3
  • 25
    • 0020041660 scopus 로고
    • Drosophila mutants with opposing effects on nerve excitability: Genetic and spatial interactions in repetitive firing
    • Ganetzky B, Wu CF (1982) Drosophila mutants with opposing effects on nerve excitability: genetic and spatial interactions in repetitive firing. J Neurophysiol 47: 501-514.
    • (1982) J Neurophysiol , vol.47 , pp. 501-514
    • Ganetzky, B.1    Wu, C.F.2
  • 27
    • 0027160708 scopus 로고
    • Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
    • Brand AH, Perrimon N (1993) Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118: 401-415.
    • (1993) Development , vol.118 , pp. 401-415
    • Brand, A.H.1    Perrimon, N.2
  • 28
    • 0031864164 scopus 로고    scopus 로고
    • Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons
    • Parkes TL, Elia AJ, Dickinson D, Hilliker AJ, Phillips JP, et al. (1998) Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons. Nat Genet 19: 171-174.
    • (1998) Nat Genet , vol.19 , pp. 171-174
    • Parkes, T.L.1    Elia, A.J.2    Dickinson, D.3    Hilliker, A.J.4    Phillips, J.P.5
  • 30
    • 0036523034 scopus 로고    scopus 로고
    • In vivo properties of the Drosophila inebriated-encoded neurotransmitter transporter
    • Huang Y, Stern M (2002) In vivo properties of the Drosophila inebriated-encoded neurotransmitter transporter. J Neurosci 22: 1698-1708.
    • (2002) J Neurosci , vol.22 , pp. 1698-1708
    • Huang, Y.1    Stern, M.2
  • 31
    • 33750023633 scopus 로고    scopus 로고
    • Akt and FOXO dysregulation contribute to infection-induced wasting in Drosophila
    • Dionne MS, Pham LN, Shirasu-Hiza M, Schneider DS (2006) Akt and FOXO dysregulation contribute to infection-induced wasting in Drosophila. Curr Biol 16: 1977-1985.
    • (2006) Curr Biol , vol.16 , pp. 1977-1985
    • Dionne, M.S.1    Pham, L.N.2    Shirasu-Hiza, M.3    Schneider, D.S.4
  • 32
    • 27144524370 scopus 로고    scopus 로고
    • Antagonistic actions of ecdysone and insulins determine final size in Drosophila
    • Colombani J, Bianchini L, Layalle S, Pondeville E, Dauphin-Villemant C, et al. (2005) Antagonistic actions of ecdysone and insulins determine final size in Drosophila. Science 310: 667-670.
    • (2005) Science , vol.310 , pp. 667-670
    • Colombani, J.1    Bianchini, L.2    Layalle, S.3    Pondeville, E.4    Dauphin-Villemant, C.5
  • 33
    • 34948908663 scopus 로고    scopus 로고
    • Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia
    • Palomero T, Sulis ML, Cortina M, Real PJ, Barnes K, et al. (2007) Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia. Nat Med 13: 1203-1210.
    • (2007) Nat Med , vol.13 , pp. 1203-1210
    • Palomero, T.1    Sulis, M.L.2    Cortina, M.3    Real, P.J.4    Barnes, K.5
  • 34
    • 4043171462 scopus 로고    scopus 로고
    • Upstream and downstream of mTOR
    • Hay N, Sonenberg N (2004) Upstream and downstream of mTOR. Genes Dev 18: 1926-1945.
    • (2004) Genes Dev , vol.18 , pp. 1926-1945
    • Hay, N.1    Sonenberg, N.2
  • 35
    • 0039425278 scopus 로고    scopus 로고
    • Negative regulation of the forkhead transcription factor FKHR by Akt
    • Tang ED, Nunez G, Barr FG, Guan KL (1999) Negative regulation of the forkhead transcription factor FKHR by Akt. J Biol Chem 274: 16741-16746.
    • (1999) J Biol Chem , vol.274 , pp. 16741-16746
    • Tang, E.D.1    Nunez, G.2    Barr, F.G.3    Guan, K.L.4
  • 36
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
    • Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA (1995) Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378: 785-789.
    • (1995) Nature , vol.378 , pp. 785-789
    • Cross, D.A.1    Alessi, D.R.2    Cohen, P.3    Andjelkovich, M.4    Hemmings, B.A.5
  • 37
    • 0242539698 scopus 로고    scopus 로고
    • The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling
    • Junger MA, Rintelen F, Stocker H, Wasserman JD, Vegh M, et al. (2003) The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling. J Biol 2: 20.
    • (2003) J Biol , vol.2 , pp. 20
    • Junger, M.A.1    Rintelen, F.2    Stocker, H.3    Wasserman, J.D.4    Vegh, M.5
  • 38
    • 2942563805 scopus 로고    scopus 로고
    • Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body
    • Hwangbo DS, Gershman B, Tu MP, Palmer M, Tatar M (2004) Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body. Nature 429: 562-566.
    • (2004) Nature , vol.429 , pp. 562-566
    • Hwangbo, D.S.1    Gershman, B.2    Tu, M.P.3    Palmer, M.4    Tatar, M.5
  • 39
    • 0036741749 scopus 로고    scopus 로고
    • Altering Drosophila S6 kinase activity is consistent with a role for S6 kinase in growth
    • Barcelo H, Stewart MJ (2002) Altering Drosophila S6 kinase activity is consistent with a role for S6 kinase in growth. Genesis 34: 83-85.
    • (2002) Genesis , vol.34 , pp. 83-85
    • Barcelo, H.1    Stewart, M.J.2
  • 41
    • 0036884297 scopus 로고    scopus 로고
    • Role of neurotrophins in central synapse formation and stabilization
    • Vicario-Abejon C, Owens D, McKay R, Segal M (2002) Role of neurotrophins in central synapse formation and stabilization. Nat Rev Neurosci 3: 965-974.
    • (2002) Nat Rev Neurosci , vol.3 , pp. 965-974
    • Vicario-Abejon, C.1    Owens, D.2    McKay, R.3    Segal, M.4
  • 42
    • 0025513585 scopus 로고
    • Morphological plasticity of motor axons in Drosophila mutants with altered excitability
    • Budnik V, Zhong Y, Wu CF (1990) Morphological plasticity of motor axons in Drosophila mutants with altered excitability. J Neurosci 10: 3754-3768.
    • (1990) J Neurosci , vol.10 , pp. 3754-3768
    • Budnik, V.1    Zhong, Y.2    Wu, C.F.3
  • 43
    • 0030273772 scopus 로고    scopus 로고
    • Genetic dissection of structural and functional components of synaptic plasticity. III. CREB is necessary for presynaptic functional plasticity
    • Davis GW, Schuster CM, Goodman CS (1996) Genetic dissection of structural and functional components of synaptic plasticity. III. CREB is necessary for presynaptic functional plasticity. Neuron 17: 669-679.
    • (1996) Neuron , vol.17 , pp. 669-679
    • Davis, G.W.1    Schuster, C.M.2    Goodman, C.S.3
  • 44
    • 1842715883 scopus 로고    scopus 로고
    • Excitatory and inhibitory switches for courtship in the brain of Drosophila melanogaster
    • Broughton SJ, Kitamoto T, Greenspan RJ (2004) Excitatory and inhibitory switches for courtship in the brain of Drosophila melanogaster. Curr Biol 14: 538-547.
    • (2004) Curr Biol , vol.14 , pp. 538-547
    • Broughton, S.J.1    Kitamoto, T.2    Greenspan, R.J.3
  • 45
    • 14744270234 scopus 로고    scopus 로고
    • Dissection of synaptic excitability phenotypes by using a dominant-negative Shaker K+ channel subunit
    • Mosca TJ, Carrillo RA, White BH, Keshishian H (2005) Dissection of synaptic excitability phenotypes by using a dominant-negative Shaker K+ channel subunit. Proc Natl Acad Sci U S A 102: 3477-3482.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 3477-3482
    • Mosca, T.J.1    Carrillo, R.A.2    White, B.H.3    Keshishian, H.4
  • 46
    • 0027279409 scopus 로고
    • Insulin-like receptor and insulin-like peptide are localized at neuromuscular junctions in Drosophila
    • Gorczyca M, Augart C, Budnik V (1993) Insulin-like receptor and insulin-like peptide are localized at neuromuscular junctions in Drosophila. J Neurosci 13: 3692-3704.
    • (1993) J Neurosci , vol.13 , pp. 3692-3704
    • Gorczyca, M.1    Augart, C.2    Budnik, V.3
  • 47
    • 0034141207 scopus 로고    scopus 로고
    • Complex interactions between mGluRs, intracellular Ca2+ stores and ion channels in neurons
    • Fagni L, Chavis P, Ango F, Bockaert J (2000) Complex interactions between mGluRs, intracellular Ca2+ stores and ion channels in neurons. Trends Neurosci 23: 80-88.
    • (2000) Trends Neurosci , vol.23 , pp. 80-88
    • Fagni, L.1    Chavis, P.2    Ango, F.3    Bockaert, J.4
  • 48
    • 32244439351 scopus 로고    scopus 로고
    • Group-II metabotropic glutamate receptors negatively modulate NMDA transmission at striatal cholinergic terminals: Role of P/Q-type high voltage activated Ca++ channels and endogenous dopamine
    • Mela F, Marti M, Fiorentini C, Missale C, Morari M (2006) Group-II metabotropic glutamate receptors negatively modulate NMDA transmission at striatal cholinergic terminals: role of P/Q-type high voltage activated Ca++ channels and endogenous dopamine. Mol Cell Neurosci 31: 284-292.
    • (2006) Mol Cell Neurosci , vol.31 , pp. 284-292
    • Mela, F.1    Marti, M.2    Fiorentini, C.3    Missale, C.4    Morari, M.5
  • 49
    • 0036457114 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 2/3-dependent long-term depression in the nucleus accumbens is blocked in morphine withdrawn mice
    • Robbe D, Bockaert J, Manzoni OJ (2002) Metabotropic glutamate receptor 2/3-dependent long-term depression in the nucleus accumbens is blocked in morphine withdrawn mice. Eur J Neurosci 16: 2231-2235.
    • (2002) Eur J Neurosci , vol.16 , pp. 2231-2235
    • Robbe, D.1    Bockaert, J.2    Manzoni, O.J.3
  • 50
    • 1642300764 scopus 로고    scopus 로고
    • Expression of K(Ca) channels in identified populations of developing vertebrate neurons: Role of neurotrophic factors and activity
    • Dryer SE, Lhuillier L, Cameron JS, Martin-Caraballo M (2003) Expression of K(Ca) channels in identified populations of developing vertebrate neurons: role of neurotrophic factors and activity. J Physiol Paris 97: 49-58.
    • (2003) J Physiol Paris , vol.97 , pp. 49-58
    • Dryer, S.E.1    Lhuillier, L.2    Cameron, J.S.3    Martin-Caraballo, M.4
  • 51
    • 38649142116 scopus 로고    scopus 로고
    • Homeostatic regulation of AMPA receptor expression at single hippocampal synapses
    • Hou Q, Zhang D, Jarzylo L, Huganir RL, Man HY (2008) Homeostatic regulation of AMPA receptor expression at single hippocampal synapses. Proc Natl Acad Sci U S A 105: 775-780.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 775-780
    • Hou, Q.1    Zhang, D.2    Jarzylo, L.3    Huganir, R.L.4    Man, H.Y.5
  • 52
    • 4344662040 scopus 로고    scopus 로고
    • PI3K promotes voltage-dependent calcium channel trafficking to the plasma membrane
    • Viard P, Butcher AJ, Halet G, Davies A, Nurnberg B, et al. (2004) PI3K promotes voltage-dependent calcium channel trafficking to the plasma membrane. Nat Neurosci 7: 939-946.
    • (2004) Nat Neurosci , vol.7 , pp. 939-946
    • Viard, P.1    Butcher, A.J.2    Halet, G.3    Davies, A.4    Nurnberg, B.5
  • 53
    • 0037115192 scopus 로고    scopus 로고
    • Leptin inhibits epileptiform-like activity in rat hippocampal neurones via PI 3-kinase-driven activation of BK channels
    • Shanley LJ, O'Malley D, Irving AJ, Ashford ML, Harvey J (2002) Leptin inhibits epileptiform-like activity in rat hippocampal neurones via PI 3-kinase-driven activation of BK channels. J Physiol 545: 933-944.
    • (2002) J Physiol , vol.545 , pp. 933-944
    • Shanley, L.J.1    O'Malley, D.2    Irving, A.J.3    Ashford, M.L.4    Harvey, J.5
  • 54
    • 34547955937 scopus 로고    scopus 로고
    • IGF-1 activates hEAG K(+) channels through an Akt-dependent signaling pathway in breast cancer cells: Role in cell proliferation
    • Borowiec AS, Hague F, Harir N, Guenin S, Guerineau F, et al. (2007) IGF-1 activates hEAG K(+) channels through an Akt-dependent signaling pathway in breast cancer cells: role in cell proliferation. J Cell Physiol 212: 690-701.
    • (2007) J Cell Physiol , vol.212 , pp. 690-701
    • Borowiec, A.S.1    Hague, F.2    Harir, N.3    Guenin, S.4    Guerineau, F.5
  • 55
    • 34548315744 scopus 로고    scopus 로고
    • An intermediate-conductance Ca(2+)-activated K (+) channel mediates B lymphoma cell cycle progression induced by serum
    • Wang J, Xu YQ, Liang YY, Gongora R, Warnock DG, et al. (2007) An intermediate-conductance Ca(2+)-activated K (+) channel mediates B lymphoma cell cycle progression induced by serum. Pflugers Arch 454: 945-956.
    • (2007) Pflugers Arch , vol.454 , pp. 945-956
    • Wang, J.1    Xu, Y.Q.2    Liang, Y.Y.3    Gongora, R.4    Warnock, D.G.5
  • 56
    • 11144355911 scopus 로고    scopus 로고
    • Bim regulation may determine hippocampal vulnerability after injurious seizures and in temporal lobe epilepsy
    • Shinoda S, Schindler CK, Meller R, So NK, Araki T, et al. (2004) Bim regulation may determine hippocampal vulnerability after injurious seizures and in temporal lobe epilepsy. J Clin Invest 113: 1059-1068.
    • (2004) J Clin Invest , vol.113 , pp. 1059-1068
    • Shinoda, S.1    Schindler, C.K.2    Meller, R.3    So, N.K.4    Araki, T.5
  • 57
    • 38149063843 scopus 로고    scopus 로고
    • Leptin inhibits 4-aminopyridine- and pentylenetetrazole-induced seizures and AMPAR-mediated synaptic transmission in rodents
    • Xu L, Rensing N, Yang XF, Zhang HX, Thio LL, et al. (2008) Leptin inhibits 4-aminopyridine- and pentylenetetrazole-induced seizures and AMPAR-mediated synaptic transmission in rodents. J Clin Invest 118: 272-280.
    • (2008) J Clin Invest , vol.118 , pp. 272-280
    • Xu, L.1    Rensing, N.2    Yang, X.F.3    Zhang, H.X.4    Thio, L.L.5
  • 58
    • 33646142995 scopus 로고    scopus 로고
    • Pten regulates neuronal arborization and social interaction in mice
    • Kwon CH, Luikart BW, Powell CM, Zhou J, Matheny SA, et al. (2006) Pten regulates neuronal arborization and social interaction in mice. Neuron 50: 377-388.
    • (2006) Neuron , vol.50 , pp. 377-388
    • Kwon, C.H.1    Luikart, B.W.2    Powell, C.M.3    Zhou, J.4    Matheny, S.A.5
  • 60
    • 0242353156 scopus 로고    scopus 로고
    • PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis
    • Rong R, Ahn JY, Huang H, Nagata E, Kalman D, et al. (2003) PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis. Nat Neurosci 6: 1153-1161.
    • (2003) Nat Neurosci , vol.6 , pp. 1153-1161
    • Rong, R.1    Ahn, J.Y.2    Huang, H.3    Nagata, E.4    Kalman, D.5
  • 61
    • 0037080171 scopus 로고    scopus 로고
    • Mutation of Drosophila homer disrupts control of locomotor activity and behavioral plasticity
    • Diagana TT, Thomas U, Prokopenko SN, Xiao B, Worley PF, et al. (2002) Mutation of Drosophila homer disrupts control of locomotor activity and behavioral plasticity. J Neurosci 22: 428-436.
    • (2002) J Neurosci , vol.22 , pp. 428-436
    • Diagana, T.T.1    Thomas, U.2    Prokopenko, S.N.3    Xiao, B.4    Worley, P.F.5
  • 62
    • 0032506514 scopus 로고    scopus 로고
    • Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway
    • Yano S, Tokumitsu H, Soderling TR (1998) Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway. Nature 396: 584-587.
    • (1998) Nature , vol.396 , pp. 584-587
    • Yano, S.1    Tokumitsu, H.2    Soderling, T.R.3
  • 63
    • 0035964314 scopus 로고    scopus 로고
    • Control of Drosophila perineurial glial growth by interacting neurotransmitter-mediated signaling pathways
    • Yager J, Richards S, Hekmat-Scafe DS, Hurd DD, Sundaresan V, et al. (2001) Control of Drosophila perineurial glial growth by interacting neurotransmitter-mediated signaling pathways. Proc Natl Acad Sci U S A 98: 10445-10450.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 10445-10450
    • Yager, J.1    Richards, S.2    Hekmat-Scafe, D.S.3    Hurd, D.D.4    Sundaresan, V.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.