-
1
-
-
0035947372
-
Impairment of the ubiquitin-proteasome system by protein aggregation
-
Bence N.F., Sampat R.M., and Kopito R.R. Impairment of the ubiquitin-proteasome system by protein aggregation. Science 292 5521 (2001) 1552-1555
-
(2001)
Science
, vol.292
, Issue.5521
, pp. 1552-1555
-
-
Bence, N.F.1
Sampat, R.M.2
Kopito, R.R.3
-
2
-
-
34547807613
-
Global changes to the ubiquitin system in Huntington's disease
-
Bennett E.J., Shaler T.A., Woodman B., Ryu K.Y., Zaitseva T.S., Becker C.H., Bates G.P., Schulman H., and Kopito R.R. Global changes to the ubiquitin system in Huntington's disease. Nature 448 7154 (2007) 704-708
-
(2007)
Nature
, vol.448
, Issue.7154
, pp. 704-708
-
-
Bennett, E.J.1
Shaler, T.A.2
Woodman, B.3
Ryu, K.Y.4
Zaitseva, T.S.5
Becker, C.H.6
Bates, G.P.7
Schulman, H.8
Kopito, R.R.9
-
3
-
-
0015901619
-
Effect of ethanol on the hydroxylation of tyrosine and tryptophan in rat brain in vivo
-
Carlsson A., and Lindqvist M. Effect of ethanol on the hydroxylation of tyrosine and tryptophan in rat brain in vivo. J. Pharm. Pharmacol. 25 6 (1973) 437-440
-
(1973)
J. Pharm. Pharmacol.
, vol.25
, Issue.6
, pp. 437-440
-
-
Carlsson, A.1
Lindqvist, M.2
-
4
-
-
0028812398
-
Cerebrospinal fluid homovanillic acid is reduced in untreated Huntington's disease
-
Garcia Ruiz P.J., Mena M.A., Sanchez Bernardos V., Diaz Neira W., Gimenez Roldan S., Benitez J., and Garcia de Yebenes J. Cerebrospinal fluid homovanillic acid is reduced in untreated Huntington's disease. Clin. Neuropharmacol. 18 1 (1995) 58-63
-
(1995)
Clin. Neuropharmacol.
, vol.18
, Issue.1
, pp. 58-63
-
-
Garcia Ruiz, P.J.1
Mena, M.A.2
Sanchez Bernardos, V.3
Diaz Neira, W.4
Gimenez Roldan, S.5
Benitez, J.6
Garcia de Yebenes, J.7
-
5
-
-
20144378366
-
Cannabinoid CB(1) receptors in the basal ganglia and motor response to activation or blockade of these receptors in parkin-null mice
-
Gonzalez S., Mena M.A., Lastres-Becker I., Serrano A., de Yebenes J.G., Ramos J.A., and Fernandez-Ruiz J. Cannabinoid CB(1) receptors in the basal ganglia and motor response to activation or blockade of these receptors in parkin-null mice. Brain Res. 1046 1-2 (2005) 195-206
-
(2005)
Brain Res.
, vol.1046
, Issue.1-2
, pp. 195-206
-
-
Gonzalez, S.1
Mena, M.A.2
Lastres-Becker, I.3
Serrano, A.4
de Yebenes, J.G.5
Ramos, J.A.6
Fernandez-Ruiz, J.7
-
6
-
-
33747768203
-
Huntington's disease: seeing the pathogenic process through a genetic lens
-
Gusella J.F., and Macdonald M.E. Huntington's disease: seeing the pathogenic process through a genetic lens. Trends Biochem. Sci. 31 9 (2006) 533-540
-
(2006)
Trends Biochem. Sci.
, vol.31
, Issue.9
, pp. 533-540
-
-
Gusella, J.F.1
Macdonald, M.E.2
-
7
-
-
0036279143
-
Molecular findings in familial Parkinson disease in Spain
-
Hoenicka J., Vidal L., Morales B., Ampuero I., Jimenez-Jimenez F.J., Berciano J., del Ser T., Jimenez A., Ruiz P.G., and de Yebenes J.G. Molecular findings in familial Parkinson disease in Spain. Arch. Neurol. 59 6 (2002) 966-970
-
(2002)
Arch. Neurol.
, vol.59
, Issue.6
, pp. 966-970
-
-
Hoenicka, J.1
Vidal, L.2
Morales, B.3
Ampuero, I.4
Jimenez-Jimenez, F.J.5
Berciano, J.6
del Ser, T.7
Jimenez, A.8
Ruiz, P.G.9
de Yebenes, J.G.10
-
8
-
-
34249802905
-
Ubiquitin-proteasome system alterations in a striatal cell model of Huntington's disease
-
Hunter J.M., Lesort M., and Johnson G.V. Ubiquitin-proteasome system alterations in a striatal cell model of Huntington's disease. J. Neurosci. Res. 85 8 (2007) 1774-1788
-
(2007)
J. Neurosci. Res.
, vol.85
, Issue.8
, pp. 1774-1788
-
-
Hunter, J.M.1
Lesort, M.2
Johnson, G.V.3
-
9
-
-
10744221310
-
Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse
-
Itier J.M., Ibanez P., Mena M.A., Abbas N., Cohen-Salmon C., Bohme G.A., Laville M., Pratt J., Corti O., Pradier L., Ret G., Joubert C., Periquet M., Araujo F., Negroni J., Casarejos M.J., Canals S., Solano R., Serrano A., Gallego E., Sanchez M., Denefle P., Benavides J., Tremp G., Rooney T.A., Brice A., and Garcia de Yebenes J. Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse. Hum. Mol. Genet. 12 18 (2003) 2277-2291
-
(2003)
Hum. Mol. Genet.
, vol.12
, Issue.18
, pp. 2277-2291
-
-
Itier, J.M.1
Ibanez, P.2
Mena, M.A.3
Abbas, N.4
Cohen-Salmon, C.5
Bohme, G.A.6
Laville, M.7
Pratt, J.8
Corti, O.9
Pradier, L.10
Ret, G.11
Joubert, C.12
Periquet, M.13
Araujo, F.14
Negroni, J.15
Casarejos, M.J.16
Canals, S.17
Solano, R.18
Serrano, A.19
Gallego, E.20
Sanchez, M.21
Denefle, P.22
Benavides, J.23
Tremp, G.24
Rooney, T.A.25
Brice, A.26
Garcia de Yebenes, J.27
more..
-
10
-
-
0034131044
-
Impaired proteasome function in Alzheimer's disease
-
Keller J.N., Hanni K.B., and Markesbery W.R. Impaired proteasome function in Alzheimer's disease. J. Neurochem. 75 1 (2000) 436-439
-
(2000)
J. Neurochem.
, vol.75
, Issue.1
, pp. 436-439
-
-
Keller, J.N.1
Hanni, K.B.2
Markesbery, W.R.3
-
11
-
-
33746487396
-
Expanded polyglutamines impair synaptic transmission and ubiquitin-proteasome system in Caenorhabditis elegans
-
Khan L.A., Bauer P.O., Miyazaki H., Lindenberg K.S., Landwehrmeyer B.G., and Nukina N. Expanded polyglutamines impair synaptic transmission and ubiquitin-proteasome system in Caenorhabditis elegans. J. Neurochem. 98 2 (2006) 576-587
-
(2006)
J. Neurochem.
, vol.98
, Issue.2
, pp. 576-587
-
-
Khan, L.A.1
Bauer, P.O.2
Miyazaki, H.3
Lindenberg, K.S.4
Landwehrmeyer, B.G.5
Nukina, N.6
-
12
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada T., Asakawa S., Hattori N., Matsumine H., Yamamura Y., Minoshima S., Yokochi M., Mizuno Y., and Shimizu N. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392 6676 (1998) 605-608
-
(1998)
Nature
, vol.392
, Issue.6676
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
Yokochi, M.7
Mizuno, Y.8
Shimizu, N.9
-
13
-
-
33344456519
-
Parkin-mediated lysine 63-linked polyubiquitination: a link to protein inclusions formation in Parkinson's and other conformational diseases?
-
Lim K.L., Dawson V.L., and Dawson T.M. Parkin-mediated lysine 63-linked polyubiquitination: a link to protein inclusions formation in Parkinson's and other conformational diseases?. Neurobiol. Aging 27 4 (2006) 524-529
-
(2006)
Neurobiol. Aging
, vol.27
, Issue.4
, pp. 524-529
-
-
Lim, K.L.1
Dawson, V.L.2
Dawson, T.M.3
-
14
-
-
0342368772
-
Association between early-onset Parkinson's disease and mutations in the parkin gene
-
Lucking C.B., Durr A., Bonifati V., Vaughan J., De Michele G., Gasser T., Harhangi B.S., Meco G., Denefle P., Wood N.W., Agid Y., and Brice A. Association between early-onset Parkinson's disease and mutations in the parkin gene. N. Engl. J. Med. 342 21 (2000) 1560-1567
-
(2000)
N. Engl. J. Med.
, vol.342
, Issue.21
, pp. 1560-1567
-
-
Lucking, C.B.1
Durr, A.2
Bonifati, V.3
Vaughan, J.4
De Michele, G.5
Gasser, T.6
Harhangi, B.S.7
Meco, G.8
Denefle, P.9
Wood, N.W.10
Agid, Y.11
Brice, A.12
-
15
-
-
16044373842
-
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
-
Mangiarini L., Sathasivam K., Seller M., Cozens B., Harper A., Hetherington C., Lawton M., Trottier Y., Lehrach H., Davies S.W., and Bates G.P. Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice. Cell 87 3 (1996) 493-506
-
(1996)
Cell
, vol.87
, Issue.3
, pp. 493-506
-
-
Mangiarini, L.1
Sathasivam, K.2
Seller, M.3
Cozens, B.4
Harper, A.5
Hetherington, C.6
Lawton, M.7
Trottier, Y.8
Lehrach, H.9
Davies, S.W.10
Bates, G.P.11
-
16
-
-
33845652619
-
Effects of chain length on the aggregation of model polyglutamine peptides: molecular dynamics simulations
-
Marchut A.J., and Hall C.K. Effects of chain length on the aggregation of model polyglutamine peptides: molecular dynamics simulations. Proteins 66 1 (2007) 96-109
-
(2007)
Proteins
, vol.66
, Issue.1
, pp. 96-109
-
-
Marchut, A.J.1
Hall, C.K.2
-
17
-
-
0036868476
-
Steele-Richardson-Olszewski syndrome in a patient with a single C212Y mutation in the parkin protein
-
Morales B., Martinez A., Gonzalo I., Vidal L., Ros R., Gomez-Tortosa E., Rabano A., Ampuero I., Sanchez M., Hoenicka J., and Garcia De Yebenes J. Steele-Richardson-Olszewski syndrome in a patient with a single C212Y mutation in the parkin protein. Mov. Disord. 17 6 (2002) 1374-1380
-
(2002)
Mov. Disord.
, vol.17
, Issue.6
, pp. 1374-1380
-
-
Morales, B.1
Martinez, A.2
Gonzalo, I.3
Vidal, L.4
Ros, R.5
Gomez-Tortosa, E.6
Rabano, A.7
Ampuero, I.8
Sanchez, M.9
Hoenicka, J.10
Garcia De Yebenes, J.11
-
18
-
-
34548331451
-
Is the ubiquitin-proteasome system impaired in Huntington's disease?
-
Ortega Z., Diaz-Hernandez M., and Lucas J.J. Is the ubiquitin-proteasome system impaired in Huntington's disease?. Cell. Mol. Life Sci. 64 17 (2007) 2245-2257
-
(2007)
Cell. Mol. Life Sci.
, vol.64
, Issue.17
, pp. 2245-2257
-
-
Ortega, Z.1
Diaz-Hernandez, M.2
Lucas, J.J.3
-
19
-
-
34247390079
-
Polyglutamine-mediated neurodegeneration: use of chaperones as prevention strategy
-
Paul S. Polyglutamine-mediated neurodegeneration: use of chaperones as prevention strategy. Biochemistry (Mosc) 72 4 (2007) 359-366
-
(2007)
Biochemistry (Mosc)
, vol.72
, Issue.4
, pp. 359-366
-
-
Paul, S.1
-
20
-
-
34548649412
-
Mortality, oxidative stress and tau accumulation during ageing in parkin null mice
-
Rodriguez-Navarro J.A., Casarejos M.J., Menendez J., Solano R.M., Rodal I., Gomez A., Yebenes J.G., and Mena M.A. Mortality, oxidative stress and tau accumulation during ageing in parkin null mice. J. Neurochem. 103 1 (2007) 98-114
-
(2007)
J. Neurochem.
, vol.103
, Issue.1
, pp. 98-114
-
-
Rodriguez-Navarro, J.A.1
Casarejos, M.J.2
Menendez, J.3
Solano, R.M.4
Rodal, I.5
Gomez, A.6
Yebenes, J.G.7
Mena, M.A.8
-
21
-
-
40749134969
-
Parkin polymorphisms in progressive supranuclear palsy
-
Ros R., Ampuero I., and Garcia de Yebenes J. Parkin polymorphisms in progressive supranuclear palsy. J. Neurol. Sci. 268 1-2 (2008) 176-178
-
(2008)
J. Neurol. Sci.
, vol.268
, Issue.1-2
, pp. 176-178
-
-
Ros, R.1
Ampuero, I.2
Garcia de Yebenes, J.3
-
22
-
-
3142604036
-
The ubiquitin-proteasome pathway in Parkinson's disease and other neurodegenerative diseases
-
Ross C.A., and Pickart C.M. The ubiquitin-proteasome pathway in Parkinson's disease and other neurodegenerative diseases. Trends Cell Biol. 14 12 (2004) 703-711
-
(2004)
Trends Cell Biol.
, vol.14
, Issue.12
, pp. 703-711
-
-
Ross, C.A.1
Pickart, C.M.2
-
23
-
-
21644446776
-
Effects of cinnarizine, a calcium antagonist that produces human parkinsonism, in parkin knock out mice
-
Serrano A., Menendez J., Casarejos M.J., Solano R.M., Gallego E., Sanchez M., Mena M.A., and Garcia de Yebenes J. Effects of cinnarizine, a calcium antagonist that produces human parkinsonism, in parkin knock out mice. Neuropharmacology 49 2 (2005) 208-219
-
(2005)
Neuropharmacology
, vol.49
, Issue.2
, pp. 208-219
-
-
Serrano, A.1
Menendez, J.2
Casarejos, M.J.3
Solano, R.M.4
Gallego, E.5
Sanchez, M.6
Mena, M.A.7
Garcia de Yebenes, J.8
-
24
-
-
33749557821
-
Cytotoxicity of a mutant huntingtin fragment in yeast involves early alterations in mitochondrial OXPHOS complexes II and III
-
Solans A., Zambrano A., Rodriguez M., and Barrientos A. Cytotoxicity of a mutant huntingtin fragment in yeast involves early alterations in mitochondrial OXPHOS complexes II and III. Hum. Mol. Genet. 15 20 (2006) 3063-3081
-
(2006)
Hum. Mol. Genet.
, vol.15
, Issue.20
, pp. 3063-3081
-
-
Solans, A.1
Zambrano, A.2
Rodriguez, M.3
Barrientos, A.4
-
25
-
-
0014481378
-
Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues
-
Tietze F. Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal. Biochem. 27 3 (1969) 502-522
-
(1969)
Anal. Biochem.
, vol.27
, Issue.3
, pp. 502-522
-
-
Tietze, F.1
-
26
-
-
27744605127
-
The ubiquitin-proteasome system in Huntington's disease
-
Valera A.G., Diaz-Hernandez M., Hernandez F., Ortega Z., and Lucas J.J. The ubiquitin-proteasome system in Huntington's disease. Neuroscientist 11 6 (2005) 583-594
-
(2005)
Neuroscientist
, vol.11
, Issue.6
, pp. 583-594
-
-
Valera, A.G.1
Diaz-Hernandez, M.2
Hernandez, F.3
Ortega, Z.4
Lucas, J.J.5
-
27
-
-
41549129945
-
Impaired ubiquitin-proteasome system activity in the synapses of Huntington's disease mice
-
Wang J., Wang C.E., Orr A., Tydlacka S., Li S.H., and Li X.J. Impaired ubiquitin-proteasome system activity in the synapses of Huntington's disease mice. J. Cell Biol. 180 6 (2008) 1177-1189
-
(2008)
J. Cell Biol.
, vol.180
, Issue.6
, pp. 1177-1189
-
-
Wang, J.1
Wang, C.E.2
Orr, A.3
Tydlacka, S.4
Li, S.H.5
Li, X.J.6
-
28
-
-
29244462838
-
In vitro analysis of huntingtin-mediated transcriptional repression reveals multiple transcription factor targets
-
Zhai W., Jeong H., Cui L., Krainc D., and Tjian R. In vitro analysis of huntingtin-mediated transcriptional repression reveals multiple transcription factor targets. Cell 123 7 (2005) 1241-1253
-
(2005)
Cell
, vol.123
, Issue.7
, pp. 1241-1253
-
-
Zhai, W.1
Jeong, H.2
Cui, L.3
Krainc, D.4
Tjian, R.5
|