Chemo-Physical and Biological Evaluation of Poly(L-lysine)-Grafted Chitosan Copolymers Used for Highly Efficient Gene Delivery

Macromolecular Bioscience

Volumn 11, Issue 3, 2011, Pages 352-361

  Yu, Haijun ^a   Deng, Chao ^a,b   Tian, Huayu ^a   Lu, Tiancheng ^a,c   Chen, Xuesi ^a   Jing, Xiabin ^a  

^a CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY   (China)

^b SOOCHOW UNIVERSITY   (China)

^c JILIN AGRICULTURAL UNIVERSITY   (China)

Author keywords

Chitosan; Gene delivery; Graft copolymers; Non viral; Poly(L lysine)

Indexed keywords

BINDING ABILITIES; BIOLOGICAL EVALUATION; GENE DELIVERY; GENE VECTORS; HIGH EFFICIENCY; IN-VITRO; IN-VIVO; L-LYSINE; LOW TOXICITY; NON-VIRAL GENE DELIVERY; NONVIRAL; POLY(L-LYSINE); POSITIVE CORRELATIONS; STARTING MATERIALS; TRANSFECTION EFFICIENCY;

AMINO ACIDS; BIOCOMPATIBILITY; CHITIN; CHITOSAN; GENE THERAPY; GENE TRANSFER; GRAFT COPOLYMERS; GRAFTING (CHEMICAL); PLASTIC PRODUCTS;

COPOLYMERIZATION;

CHITOSAN; COPOLYMER; POLYLYSINE;

ARTICLE; DNA BINDING; GENE VECTOR; GENETIC TRANSFECTION; IN VITRO GENE TRANSFER; NONVIRAL GENE DELIVERY SYSTEM; PHYSICAL CHEMISTRY; SYNTHESIS;

CELL SURVIVAL; CHITOSAN; DNA; ELECTROPHORESIS, AGAR GEL; GENE TRANSFER TECHNIQUES; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HELA CELLS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MICROSCOPY, FLUORESCENCE; PARTICLE SIZE; PHYSICOCHEMICAL PHENOMENA; PLASMIDS; POLYLYSINE; STATIC ELECTRICITY; TRANSFECTION;

EID: 79952080487     PISSN: 16165187     EISSN: 16165195     Source Type: Journal    
DOI: 10.1002/mabi.201000283     Document Type: Article

References (45)

1. M. Cotten, F. Langlerouault, H. Kirlappos, E. Wagner, K. Mechtler, M. Zenke, H. Beug, M. L. Birnstiel, Proc. Nat. Acad. Sci. USA 1990, 87, 4033;
2. M. Meyer, E. Wagner, Human Gene Ther. 2006, 17, 1062;
3. S. D. Li, L. Huang, J. Controlled Release 2007, 123, 181;
4. G. Zuber, E. Dauty, M. Nothisen, P. Belguise, J. P. Behr, Adv. Drug Deliv. Rev. 2001, 52, 245;
5. Y. Yang, W. X. Jia, X. Qi, C. Yang, L. Liu, Z. R. Zhang, J. H. Ma, S. B. Zhou, X. H. Li, Macromol. Biosci. 2004, 4, 1113.
6. K. A. Whitehead, R. Langer, D. G. Anderson, Nat. Rev. Drug Discov. 2009, 8, 129;
7. H. J. Yu, E. Wagner, Curr. Opin. Mol. Ther. 2009, 11, 165.
8. C. L. Gebhart, A. V. Kabanov, J. Controlled Release 2001, 73, 401;
9. B. Demeneix, J. P. Behr, Adv. Genet. 2005, 53, 217;
10. A. Baker, M. Saltik, H. Lehrmann, I. Killisch, V. Mautner, G. Lamm, G. Christofori, M. Cotten, Gene. Ther. 1997, 4, 773;
11. J. Chen, H. Y. Tian, Z. P. Guo, J. L. Xia, A. Kano, A. Maruyama, X. B. Jing, X. S. Chen, Macromol. Biosci. 2009, 9, 1247.
12. J. Kloeckner, E. Wagner, M. Ogris, Eur. J. Pharm. Sci. 2006, 29, 414;
13. H. J. Yu, V. Russ, E. Wagner, AAPS J. 2009, 11, 445.
14. E. Wagner, M. Zenke, M. Cotten, H. Beug, M. L. Birnstiel, Proc. Natl. Acad. Sci. USA 1990, 87, 3410;
15. M. Harada-Shiba, K. Yamauchi, A. Harada, I. Takamisawa, K. Shimokado, K. Kataoka, Gene Therapy 2002, 9, 407.
16. M. Ogris, R. C. Carlisle, T. Bettinger, L. W. Seymour, J. Biol. Chem. 2001, 276, 47550.
17. M. Meyer, A. Philipp, R. Oskuee, C. Schmidt, E. Wagner, J. Am. Chem. Soc. 2008, 130, 3272.
18. G. Borchard, Adv. Drug Deliver. Rev. 2001, 52, 145.
19. A. K. Singla, M. Chawla, J. Pharm. Pharmacol. 2001, 53, 1047.
20. T. Kean, M. Thanou, Adv. Drug Deliv. Rev. 2010, 62, 3.
21. S. R. Mao, W. Sun, T. Kissel, Adv. Drug Deliv. Rev. 2010, 62, 3;
22. J. M. Dang, K. W. Leong, Adv. Drug Deliv. Rev. 2006, 58, 487;
23. Y. Gao, Z. W. Zhang, L. L. Chen, W. W. Gu, Y. P. Li, Biomacromolecules 2009, 10, 2175.
24. H. J. Yu, X. S. Chen, T. C. Lu, J. Sun, H. Y. Tian, J. Hu, Y. Wang, P. B. Zhang, X. B. Jing, Biomacromolecules 2007, 8, 1425.
25. H. J. Yu, W. S. Wang, X. S. Chen, C. Deng, X. B. Jing, Biopolymers 2006, 83, 233;
26. C. Deng, H. Y. Tian, P. B. Zhang, J. Sun, X. S. Chen, X. B. Jing, Biomacromolecules 2006, 7, 590.
27. J. Holappa, T. Nevalainen, J. Savolainen, P. Soininen, M. Elomaa, R. Safin, S. Suvanto, T. Pakkanen, M. Masson, T. Loftsson, T. Jarvinen, Macromolecules 2004, 37, 2784.
28. Y. M. Liu, T. M. Reineke, J. Am. Chem. Soc. 2005, 127, 3004.
29. Y. M. Liu, T. M. Reineke, Bioconjugate Chem. 2007, 18, 19.
30. K. Roy, H. Q. Mao, S. K. Huang, K. W. Leong, Nat. Med. 1999, 5, 387;
31. Z. W. Mao, L. Ma, Y. Jiang, M. Yan, C. Y. Gao, J. C. Shen, Macromol. Biosci. 2007, 7, 855.
32. G. W. Wang, X. L. Luo, Y. N. Zhang, J. L. Huang, J. Polym. Sci. ; Part A: Polym. Chem. 2009, 47, 4800.
33. P. Midoux, C. Pichon, J. J. Yaouanc, P. A. Jaffres, Brit. J. Pharmacol. 2009, 157, 166;
34. K. A. Howard, J. Kjems, Expert. Opin. Biol. Th. 2007, 7, 1811.
35. K. Remaut, N. N. Sanders, F. Fayazpour, J. Demeester, S. C. De Smedt, J. Controlled Release 2006, 115, 335.
36. Y. Capan, B. H. Woo, S. Gebrekidan, S. Ahmed, P. P. DeLuca, Pharm. Dev. Tech. 1999, 4, 491.
37. W. F. Lai, M. C. M. Lin, J. Controlled Release 2009, 134, 158.
38. E. H. Chowdhury, Expert. Opin. Drug Del. 2009, 6, 697;
39. E. Wagner, Pharm. Res. 2004, 21, 8.
40. O. Boussif, F. Lezoualch, M. A. Zanta, M. D. Mergny, D. Scherman, B. Demeneix, J. P. Behr, P. Natl. Acad. Sci. USA 1995, 92, 7297.
41. M. Koping-Hoggard, K. M. Varum, M. Issa, S. Danielsen, B. E. Christensen, B. T. Stokke, P. Artursson, Gene Therapy 2004, 11, 1441.
42. C. L. Dong, G. L. Wen, J. Z. Ai, J. S. Shu, C. Nan, G. Gang, Y. Z. Jing, D. Y. Kang, Int. J. Pharm. 2006, 314, 63.
43. A. Pattani, V. B. Patravale, L. Panicker, P. D. Potdar, Mol. Pharm. 2009, 6, 345.
44. D. V. Schaffer, D. A. Lauffenburger, J. Biol. Chem. 1998, 273, 28004.
45. M. Thibault, S. Nimesh, M. Lavertu, M. D. Buschmann, Mol. Therapy 2010, 18, 1787.