Systematic Screening for Catalytic Promiscuity in 4-Oxalocrotonate Tautomerase: Enamine Formation and Aldolase Activity

ChemBioChem

Volumn 12, Issue 4, 2011, Pages 602-609

  Zandvoort, Ellen ^a   Baas, Bert Jan ^a   Quax, Wim J ^a   Poelarends, Gerrit J ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Aldol reaction; Catalytic promiscuity; Enamine catalysis; Enzyme catalysis; Tautomerases

Indexed keywords

4 OXALOCROTONATE TAUTOMERASE; ACETALDEHYDE; ALDEHYDE; AMINE; BENZALDEHYDE; CINNAMALDEHYDE; ENAMINE; FRUCTOSE BISPHOSPHATE ALDOLASE; IMINE; ISOMERASE; KETONE; LYSINE; NUCLEOPHILE; PROLINE; UNCLASSIFIED DRUG;

ALDOL REACTION; ARTICLE; BIOCATALYST; CATALYSIS; CHEMICAL BOND; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME MODIFICATION; MASS SPECTROMETRY; NONHUMAN; PH; POINT MUTATION; PRIORITY JOURNAL; PROTON TRANSPORT; SCREENING; WILD TYPE;

BIPHENYL COMPOUNDS; CATALYSIS; CATALYTIC DOMAIN; FRUCTOSE-BISPHOSPHATE ALDOLASE; GENETIC VECTORS; IMIDAZOLES; ISOMERASES; MOLECULAR STRUCTURE; MUTATION; PSEUDOMONAS PUTIDA; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SUBSTRATE SPECIFICITY;

PSEUDOMONAS PUTIDA;

EID: 79952028974     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.201000633     Document Type: Article

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