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Volumn 51, Issue , 2011, Pages 359-372

Mechanisms of monoclonal antibody-drug interactions

Author keywords

cytokine; disease drug interaction; pharmacokinetics

Indexed keywords

ABCIXIMAB; ADALIMUMAB; ALEMTUZUMAB; BASILIXIMAB; BEVACIZUMAB; CANAKINUMAB; CAPROMAB PENDETIDE IN 111; CERTOLIZUMAB PEGOL; CETUXIMAB; DACLIZUMAB; ECULIZUMAB; EFALIZUMAB; FANOLESOMAB TC 99M; GOLIMUMAB; IBRITUMOMAB TIUXETAN; INFLIXIMAB; MONOCLONAL ANTIBODY; NATALIZUMAB; NOFETUMOMAB MERPENTAN TC 99M; OKT 3; OMALIZUMAB; PALIVIZUMAB; PANITUMUMAB; RANIBIZUMAB; RITUXIMAB; TOCILIZUMAB; TOSITUMOMAB; TRASTUZUMAB; UNINDEXED DRUG; VERAPAMIL;

EID: 79952001750     PISSN: 03621642     EISSN: 15454304     Source Type: Book Series    
DOI: 10.1146/annurev-pharmtox-010510-100510     Document Type: Article
Times cited : (69)

References (77)
  • 1
    • 0000057167 scopus 로고
    • Experimentelle untersuchungen über immunitat. I. Ueber ricin
    • Ehrlich P. 1891. Experimentelle untersuchungen über immunitat. I. Ueber ricin. Dtsch. Med. Wochenschr. 17:976-79
    • (1891) Dtsch. Med. Wochenschr. , vol.17 , pp. 976-79
    • Ehrlich, P.1
  • 2
    • 0021416934 scopus 로고
    • Origin of the terms "antibody" and "antigen."
    • Lindenmann J. 1984. Origin of the terms "antibody" and "antigen." Scand. J. Immunol. 194:281-85
    • (1984) Scand. J. Immunol. , vol.194 , pp. 281-85
    • Lindenmann, J.1
  • 3
    • 0033581251 scopus 로고    scopus 로고
    • The Nobel chronicles. 1972: GeraldMEdelman(b 1929) and Rodney R Porter (1917-85)
    • RajuTN. 1999. The Nobel chronicles. 1972: GeraldMEdelman(b 1929) and Rodney R Porter (1917-85). Lancet 354(9183):1040
    • (1999) Lancet , vol.354 , Issue.9183 , pp. 1040
    • Raju, T.N.1
  • 4
    • 54249138516 scopus 로고    scopus 로고
    • Monoclonal antibody pharmacokinetics and pharmacodynamics
    • Wang W, Wang EQ, Balthasar JP. 2008. Monoclonal antibody pharmacokinetics and pharmacodynamics. Clin. Pharmacol. Ther. 845:548-58
    • (2008) Clin. Pharmacol. Ther. , vol.845 , pp. 548-58
    • Wang, W.1    Wang, E.Q.2    Balthasar, J.P.3
  • 5
    • 79551588087 scopus 로고    scopus 로고
    • CYP-mediated therapeutic protein-drug interactions: Clinical findings, proposed mechanisms and regulatory implications
    • Lee J-I, Zhang L, Men AY, Kenna LA, Huang S-M. 2010. CYP-mediated therapeutic protein-drug interactions: clinical findings, proposed mechanisms and regulatory implications. Clin. Pharmacokinet. 495:295-310
    • (2010) Clin. Pharmacokinet. , vol.495 , pp. 295-310
    • Lee, J.-I.1    Zhang, L.2    Men, A.Y.3    Kenna, L.A.4    Huang, S.-M.5
  • 6
    • 58149269468 scopus 로고    scopus 로고
    • Use of prescription and over-the-counter medications and dietary supplements among older adults in the United States
    • Qato DM, Alexander GC, Conti RM, Johnson M, Schumm P, Tessler Lindau S, et al. 2008. Use of prescription and over-the-counter medications and dietary supplements among older adults in the United States. J. Am. Med. Assoc. 300(24):2867-78
    • (2008) J. Am. Med. Assoc. , vol.300 , Issue.24 , pp. 2867-78
    • Qato, D.M.1    Alexander, G.C.2    Conti, R.M.3    Johnson, M.4    Schumm, P.5    Tessler Lindau, S.6
  • 7
    • 41149106199 scopus 로고    scopus 로고
    • Pharmacokinetic drug-drug interaction potentials for therapeutic monoclonal antibodies: Reality check
    • Seitz K, Zhou H. 2007. Pharmacokinetic drug-drug interaction potentials for therapeutic monoclonal antibodies: reality check. J. Clin. Pharmacol. 47:1104-18
    • (2007) J. Clin. Pharmacol. , vol.47 , pp. 1104-18
    • Seitz, K.1    Zhou, H.2
  • 8
    • 36148968010 scopus 로고    scopus 로고
    • Drug interaction studies of therapeutic proteins or monoclonal antibodies
    • DOI 10.1177/0091270007308616
    • MahmoodI, GreenMD. 2007. Drug interaction studies of therapeutic proteins or monoclonal antibodies. J. Clin. Pharmacol. 47:1540-54 (Pubitemid 350115304)
    • (2007) Journal of Clinical Pharmacology , vol.47 , Issue.12 , pp. 1540-1554
    • Mahmood, I.1    Green, M.D.2
  • 9
    • 69749119482 scopus 로고    scopus 로고
    • Risk-based strategy for the assessment of pharmacokinetic drug-drug interactions for therapeutic monoclonal antibodies
    • Zhou H, Davis HM. 2009. Risk-based strategy for the assessment of pharmacokinetic drug-drug interactions for therapeutic monoclonal antibodies. Drug Discov. Today 14:891-98
    • (2009) Drug Discov. Today , vol.14 , pp. 891-98
    • Zhou, H.1    Davis, H.M.2
  • 10
    • 77949872821 scopus 로고    scopus 로고
    • Therapeutic protein-drug interactions and implications for drug development
    • Huang SM, Zhao H, Lee JI, Reynolds K, Zhang L, et al. 2010. Therapeutic protein-drug interactions and implications for drug development. Clin. Pharmacol. Ther. 87:497-503
    • (2010) Clin. Pharmacol. Ther. , vol.87 , pp. 497-503
    • Huang, S.M.1    Zhao, H.2    Lee, J.I.3    Reynolds, K.4    Zhang, L.5
  • 11
    • 79951992891 scopus 로고    scopus 로고
    • Current knowledge on clearance mechanisms: Drug-drug interaction potential for monoclonal antibodies with other protein biotherapeutics and small molecule drugs
    • June 22-25, Toronto
    • Theil FP. 2008. Current knowledge on clearance mechanisms: drug-drug interaction potential for monoclonal antibodies with other protein biotherapeutics and small molecule drugs. Presented at AAPS Natl. Biotechnol. Conf, June 22-25, Toronto
    • (2008) Presented at AAPS Natl. Biotechnol. Conf
    • Theil, F.P.1
  • 12
    • 0000146003 scopus 로고
    • A theoretical model of y-globulin catabolism
    • Brambell FWR, Hemmings WA, Morris IG. 1964. A theoretical model of y-globulin catabolism. Nature 203:1352-55
    • (1964) Nature , vol.203 , pp. 1352-55
    • Brambell, F.W.R.1    Hemmings, W.A.2    Morris, I.G.3
  • 13
    • 0014022299 scopus 로고
    • The transmission of immunity from mother to young and the catabolism of immunoglobulins
    • Brambell FW. 1966. The transmission of immunity from mother to young and the catabolism of immunoglobulins. Lancet 2:1087-93
    • (1966) Lancet , vol.2 , pp. 1087-93
    • Brambell, F.W.1
  • 15
    • 0030993535 scopus 로고    scopus 로고
    • Finally! the Brambell receptor (FcRB). Mediator of transmission of immunity and protection from catabolism for IgG
    • Junghans RP. 1997. Finally! The Brambell receptor (FcRB). Mediator of transmission of immunity and protection from catabolism for IgG. Immunol. Res. 16:29-57
    • (1997) Immunol. Res. , vol.16 , pp. 29-57
    • Junghans, R.P.1
  • 16
    • 0031449358 scopus 로고    scopus 로고
    • FcRn: The MHC class I-related receptor that is more than an IgG transporter
    • DOI 10.1016/S0167-5699(97)01172-9, PII S0167569997011729
    • Ghetie V, Ward ES. 1997. FcRn: the MHC class I-related receptor that is more than an IgG transporter. Immunol. Today 18:592-98 (Pubitemid 28012280)
    • (1997) Immunology Today , vol.18 , Issue.12 , pp. 592-598
    • Ghetie, V.1    Ward, E.S.2
  • 17
    • 0036201914 scopus 로고    scopus 로고
    • Transcytosis and catabolism of antibody
    • Ghetie V, Ward ES. 2002. Transcytosis and catabolism of antibody. Immunol. Res. 25:97-113 (Pubitemid 34264097)
    • (2002) Immunologic Research , vol.25 , Issue.2 , pp. 97-113
    • Ghetie, V.1    Ward, E.S.2
  • 18
    • 0031409592 scopus 로고    scopus 로고
    • Regulation of cytochromes P450 during inflammation and infection
    • Morgan ET. 1997. Regulation of cytochromes P450 during inflammation and infection. Drug Metab. Rev. 29:1129-88 (Pubitemid 28133460)
    • (1997) Drug Metabolism Reviews , vol.29 , Issue.4 , pp. 1129-1188
    • Morgan, E.T.1
  • 19
    • 20444467357 scopus 로고    scopus 로고
    • Important role of proinflammatory cytokines/other endogenous substances in drug-induced hepatotoxicity: Depression of drug metabolism during infections/inflammation states, and genetic polymorphisms of drug-metabolizing enzymes/cytokines may markedly contribute to this pathology
    • Prandota J. 2005. Important role of proinflammatory cytokines/other endogenous substances in drug-induced hepatotoxicity: depression of drug metabolism during infections/inflammation states, and genetic polymorphisms of drug-metabolizing enzymes/cytokines may markedly contribute to this pathology. Am. J. Ther. 12:254-61 (Pubitemid 40825131)
    • (2005) American Journal of Therapeutics , vol.12 , Issue.3 , pp. 254-261
    • Prandota, J.1
  • 20
    • 62649091120 scopus 로고    scopus 로고
    • Impact of infectious and inflammatory disease on cytochrome P450-mediated drug metabolism and pharmacokinetics
    • Morgan ET. 2009. Impact of infectious and inflammatory disease on cytochrome P450-mediated drug metabolism and pharmacokinetics. Clin. Pharmacol. Ther. 85:434-38
    • (2009) Clin. Pharmacol. Ther. , vol.85 , pp. 434-38
    • Morgan, E.T.1
  • 22
    • 61449142646 scopus 로고    scopus 로고
    • Regulation of drug transporter expression in human hepatocytes exposed to the proinflammatory cytokines tumor necrosis factor- a. or interleukin-6
    • LeVee LM, Lecureur V, Stieger B, Fardel O. 2009. Regulation of drug transporter expression in human hepatocytes exposed to the proinflammatory cytokines tumor necrosis factor- a. or interleukin-6. Drug Metab. Dispos. 37:685-93
    • (2009) Drug Metab. Dispos. , vol.37 , pp. 685-93
    • Levee, L.M.1    Lecureur, V.2    Stieger, B.3    Fardel, O.4
  • 23
    • 33144485957 scopus 로고    scopus 로고
    • Regulation of drug-metabolizing enzymes and transporters in inflammation
    • DOI 10.1146/annurev.pharmtox.46.120604.141059
    • AitkenAE, Richardson TA,MorganET. 2006. Regulation of drug-metabolizing enzymes and transporters in inflammation. Annu. Rev. Pharmacol. Toxicol. 46:123-49 (Pubitemid 43271186)
    • (2006) Annual Review of Pharmacology and Toxicology , vol.46 , pp. 123-149
    • Aitken, A.E.1    Richardson, T.A.2    Morgan, E.T.3
  • 24
    • 0008732635 scopus 로고
    • Enhanced phenobarbital induction of liver microsomal drug-metabolizing enzymes in mice infected with murine hepatitus virus
    • Kato R, Nakamura Y, Chiesara E. 1963. Enhanced phenobarbital induction of liver microsomal drug-metabolizing enzymes in mice infected with murine hepatitus virus. Biochem. Pharmacol. 12:365-70
    • (1963) Biochem. Pharmacol. , vol.12 , pp. 365-70
    • Kato, R.1    Nakamura, Y.2    Chiesara, E.3
  • 25
    • 0018190964 scopus 로고
    • Altered theophylline pharmacokinetics during acute respiratory viral illness
    • Chang KC, Lauer BA, Bell TD, Chai H. 1978. Altered theophylline pharmacokinetics during acute respiratory viral illness. Lancet 311:1132-33 (Pubitemid 8356442)
    • (1978) Lancet , vol.1 , Issue.8074 , pp. 1132-1133
    • Chang, K.C.1    Bell, T.D.2    Lauer, B.A.3    Chai, H.4
  • 26
    • 0020056612 scopus 로고
    • Altered theophylline clearance during an influenza B outbreak
    • Kraemer MJ, Furukawa CT, Koup JR, Shapiro GG, Pierson WE, Bierman CW. 1982. Altered theophylline clearance during an influenza B outbreak. Pediatrics 69:476-80 (Pubitemid 12135951)
    • (1982) Pediatrics , vol.69 , Issue.4 , pp. 476-480
    • Kraemer, M.J.1    Furukawa, C.T.2    Koup, J.R.3
  • 27
    • 0017079210 scopus 로고
    • Decrease in the activity of the drug-metabolizing enzymes of rat liver following the administration of tilorone hydrochloride
    • Leeson GA, Biedenbach SA, Chan KY, Gibson JP, Wright GJ. 1976. Decrease in the activity of the drug-metabolizing enzymes of rat liver following the administration of tilorone hydrochloride. Drug Metab. Dispos. 4:232-38
    • (1976) Drug Metab. Dispos. , vol.4 , pp. 232-38
    • Leeson, G.A.1    Biedenbach, S.A.2    Chan, K.Y.3    Gibson, J.P.4    Wright, G.J.5
  • 28
    • 0017192259 scopus 로고
    • Depression of hepatic cytochrome P-450-dependent monooxygenase systems with administered interferon inducing agents
    • Renton KW, Mannering GJ. 1976. Depression of hepatic cytochrome P-450-dependent monooxygenase systems with administered interferon inducing agents. Biochem. Biophys. Res. Commun. 73:343-48
    • (1976) Biochem. Biophys. Res. Commun. , vol.73 , pp. 343-48
    • Renton, K.W.1    Mannering, G.J.2
  • 31
    • 0031025257 scopus 로고    scopus 로고
    • Cytochrome P4501A1 and cytochrome P4501A2 are downregulated at both transcriptional and post-transcriptional levels by conditions resulting in interferon-α/β induction
    • DOI 10.1016/S0024-3205(97)00006-4, PII S0024320597000064
    • Delaporte E, Renton KW. 1997. Cytochrome P4501A1 and cytochrome P4501A2 are downregulated at both transcriptional and post-transcriptional levels by conditions resulting in interferon- a/13 induction. Life Sci. 60:787-96 (Pubitemid 27087271)
    • (1997) Life Sciences , vol.60 , Issue.10 , pp. 787-796
    • Delaporte, E.1    Renton, K.W.2
  • 34
    • 0023230059 scopus 로고
    • Inhibition of theophylline metabolism by interferon
    • Williams SJ, Baird-Lambert JA, Farrell GC. 1987. Inhibition of theophylline metabolism by interferon. Lancet 330:939-41 (Pubitemid 17150287)
    • (1987) Lancet , vol.2 , Issue.8565 , pp. 939-941
    • Williams, S.J.1    Baird-Lambert, J.A.2    Farrell, G.C.3
  • 35
    • 0019843503 scopus 로고
    • Interferon-mediated depression of cytochrome P-450-dependent drug biotransformation
    • Singh G, Renton KW. 1981. Interferon-mediated depression of cytochrome P-450-dependent drug biotransformation. Mol. Pharmacol. 20:681-84 (Pubitemid 12252294)
    • (1981) Molecular Pharmacology , vol.20 , Issue.3 , pp. 681-684
    • Singh, G.1    Renton, K.W.2
  • 36
    • 0019446311 scopus 로고
    • Depression of hepatic cytochrome P-450-dependent mixed function oxidases during infection with encephalomyocarditis virus
    • DOI 10.1016/0006-2952(81)90107-6
    • Renton KW. 1981. Depression of hepatic cytochrome P-450-dependent mixed function oxidases during infection with encephalomyocarditis virus. Biochem. Pharmacol. 30:2333-36 (Pubitemid 11048325)
    • (1981) Biochemical Pharmacology , vol.30 , Issue.16 , pp. 2333-2336
    • Renton, K.W.1
  • 38
    • 0031931324 scopus 로고    scopus 로고
    • The effect of chronic retrovirus infection and immune dysfunction on the P-450-mediated activation of acetaminophen in mouse liver microsomes
    • DOI 10.1002/(SICI)1099-081X(199801)19:1<9::AID-BDD70>3.0.CO;2-F
    • Chow HH, Tang Y, Li P, Brookshier G, Liang B, Watson R. 1998. The effect of chronic retrovirus infection and immune dysfunction on the P-450-mediated activation of acetaminophen in mouse liver microsomes. Biopharm. Drug Dispos. 19:9-15 (Pubitemid 28064486)
    • (1998) Biopharmaceutics and Drug Disposition , vol.19 , Issue.1 , pp. 9-15
    • Chow, H.-H.1    Tang, Y.2    Li, P.3    Brookshier, G.4    Liang, B.5    Watson, R.6
  • 40
    • 70349398811 scopus 로고
    • Physiopathology of detoxification of pentobarbital sodium
    • Samaras SC,DietzN 1953. Physiopathology of detoxification of pentobarbital sodium. FASEBJ. 12:122-25
    • (1953) FASEB J. , vol.12 , pp. 122-25
    • Samaras, S.C.1    Dietz, N.2
  • 41
    • 0028007169 scopus 로고
    • Endotoxin administration to humans inhibits hepatic cytochrome P450-mediated drug metabolism
    • Shedlofsky SI, Israel BC, McClain CJ, Hill DB, Blouin RA. 1994. Endotoxin administration to humans inhibits hepatic cytochrome P450-mediated drug metabolism. J. Clin. Investig. 94:2209-14
    • (1994) J. Clin. Investig. , vol.94 , pp. 2209-14
    • Shedlofsky, S.I.1    Israel, B.C.2    McClain, C.J.3    Hill, D.B.4    Blouin, R.A.5
  • 43
    • 0028021853 scopus 로고
    • Elevation of circulating interleukin 6 after surgery: Factors influencing the serum level
    • DOI 10.1016/1043-4666(94)90040-X
    • Sakamoto K, Arakawa H, Mita S, Ishiko T, Ikei S, et al. 1994. Elevation of circulating interleukin 6 after surgery: factors influencing the serum level. Cytokine 6:181-86 (Pubitemid 24263857)
    • (1994) Cytokine , vol.6 , Issue.2 , pp. 181-186
    • Sakamoto, K.1    Arakawa, H.2    Mita, S.3    Ishiko, T.4    Ikei, S.5    Egami, H.6    Hisano, S.7    Ogawa, M.8
  • 44
    • 0029970424 scopus 로고    scopus 로고
    • Changes in interleukin-6 concentrations following epilepsy surgery: Potential influence on carbamazepine pharmacokinetics [2]
    • Gidal BE, Reiss WG, Liao JS, Pitterle ME. 1996. Changes in interleukin-6 concentrations following epilepsy surgery: potential influence on carbamazepine pharmacokinetics. Ann. Pharmacother. 30:545-46 (Pubitemid 26139256)
    • (1996) Annals of Pharmacotherapy , vol.30 , Issue.5 , pp. 545-546
    • Gidal, B.E.1    Reiss, W.G.2    Liao, J.S.3    Pitterle, M.E.4
  • 45
    • 34548090571 scopus 로고    scopus 로고
    • Gene-specific effects of inflammatory cytokines on cytochrome P450 2C, 2B6 and 3A4 mRNA levels in human hepatocytes
    • DOI 10.1124/dmd.107.015511
    • Aitken AE, Morgan ET. 2007. Gene-specific effects of inflammatory cytokines on cytochrome P450 2C, 2B6 and 3A4 mRNAlevels in human hepatocytes. Drug Metab. Dispos. 35:1687-93 (Pubitemid 47296065)
    • (2007) Drug Metabolism and Disposition , vol.35 , Issue.9 , pp. 1687-1693
    • Aitken, A.E.1    Morgan, E.T.2
  • 46
    • 15344338966 scopus 로고    scopus 로고
    • Effect of early phase adjuvant arthritis on hepatic P450 enzymes and pharmacokinetics of verapamil: An alternative approach to the use of an animal model of inflammation for pharmacokinetic studies
    • DOI 10.1124/dmd.104.002360
    • Ling S, Jamali F. 2005. Effect of early phase adjuvant arthritis on hepatic P450 enzymes and pharmacokinetics of verapamil: an alternative approach to the use of an animal model of inflammation for pharmacokinetic studies. Drug. Metab. Dispos. 33:579-86 (Pubitemid 40393202)
    • (2005) Drug Metabolism and Disposition , vol.33 , Issue.4 , pp. 579-586
    • Ling, S.1    Jamali, F.2
  • 48
    • 0015948535 scopus 로고
    • Adjuvant disease in rats: Biochemical criteria for distinguishing several phases of inflammation and arthritis
    • Baumgartner WA, Beck FW, Lorber A, Pearson CM, Whitehouse MW. 1974. Adjuvant disease in rats: biochemical criteria for distinguishing several phases of inflammation and arthritis. Proc. Soc. Exp. Biol. Med. 145:625-30
    • (1974) Proc. Soc. Exp. Biol. Med. , vol.145 , pp. 625-30
    • Baumgartner, W.A.1    Beck, F.W.2    Lorber, A.3    Pearson, C.M.4    Whitehouse, M.W.5
  • 49
    • 0037407441 scopus 로고    scopus 로고
    • Disease-drug interaction: Reduced response to propranolol despite increased concentration in the rat with inflammation
    • DOI 10.1002/jps.10381
    • Guirguis MS, Jamali F. 2003. Disease-drug interaction: reduced response to propranolol despite increased concentration in the rat with inflammation. J. Pharm. Sci. 92:1077-84 (Pubitemid 36523454)
    • (2003) Journal of Pharmaceutical Sciences , vol.92 , Issue.5 , pp. 1077-1084
    • Guirguis, M.S.1    Jamali, F.2
  • 50
    • 67651205738 scopus 로고    scopus 로고
    • The effect of infliximab on hepatic cytochrome P450 and pharmacokinetics of verapamil in rats with pre-adjuvant arthritis: A drug-disease and drug-drug interaction
    • Ling S, Jamali F. 2009. The effect of infliximab on hepatic cytochrome P450 and pharmacokinetics of verapamil in rats with pre-adjuvant arthritis: a drug-disease and drug-drug interaction. Basic Clin. Pharmacol. Toxicol. 105:24-29
    • (2009) Basic Clin. Pharmacol. Toxicol. , vol.105 , pp. 24-29
    • Ling, S.1    Jamali, F.2
  • 51
    • 0017147272 scopus 로고
    • Plasma levels of propranolol in treated patients with celiac disease and patients with Crohn's disease
    • Schneider RE, Babb J, Bishop H, Mitchard M, Hoare AM. 1976. Plasma levels of propranolol in treated patients with celiac disease and patients with Crohn's disease. Br. Med. J. 2:794-95
    • (1976) Br. Med. J. , vol.2 , pp. 794-95
    • Schneider, R.E.1    Babb, J.2    Bishop, H.3    Mitchard, M.4    Hoare, A.M.5
  • 52
    • 0034536649 scopus 로고    scopus 로고
    • Decreased dromotropic response to verapamil despite pronounced increased drug concentration in rheumatoid arthritis
    • DOI 10.1046/j.1365-2125.2000.00314.x
    • Mayo PR, Skeith K, Russell AS, Jamali F. 2000. Decreased dromotropic response to verapamil despite pronounced increased drug concentration in rheumatoid arthritis. Br. J. Clin. Pharmacol. 50:605-13 (Pubitemid 32010020)
    • (2000) British Journal of Clinical Pharmacology , vol.50 , Issue.6 , pp. 605-613
    • Mayo, P.R.1    Skeith, K.2    Russell, A.S.3    Jamali, F.4
  • 53
    • 61449234078 scopus 로고    scopus 로고
    • Influence of controlled rheumatoid arthritis on the action and disposition of verapamil: Focus on infliximab
    • Ling S, Lewanczuk RZ, Russell AS, Ihejirika B, Jamali F. 2009. Influence of controlled rheumatoid arthritis on the action and disposition of verapamil: focus on infliximab. J. Clin. Pharmacol. 49:301-11
    • (2009) J. Clin. Pharmacol. , vol.49 , pp. 301-11
    • Ling, S.1    Lewanczuk, R.Z.2    Russell, A.S.3    Ihejirika, B.4    Jamali, F.5
  • 54
    • 77949873408 scopus 로고    scopus 로고
    • Disease-drug interaction studies of tocilizumab with cytochrome p450 substrate in vitro and in vivo
    • Abstr.
    • Zhang X, Schmitt C, Grange S, Terao K, Miya K. 2009. Disease-drug interaction studies of tocilizumab with cytochrome p450 substrate in vitro and in vivo. Clin. Pharmacol. Ther. 85:S59 (Abstr.)
    • (2009) Clin. Pharmacol. Ther. , vol.85
    • Zhang, X.1    Schmitt, C.2    Grange, S.3    Terao, K.4    Miya, K.5
  • 56
    • 79951985290 scopus 로고    scopus 로고
    • An academic view of therapeutic protein drug-drug interactions
    • Presented at May 15-16, San Francisco
    • Balthasar JP. 2010. An academic view of therapeutic protein drug-drug interactions. Presented at AAPS Workshop Ther. Protein Drug Interact., May 15-16, San Francisco
    • (2010) AAPS Workshop Ther. Protein Drug Interact.
    • Balthasar, J.P.1
  • 59
    • 0345407949 scopus 로고    scopus 로고
    • Chicago IL: Abbott Laboratories
    • Humira [package insert]. Chicago, IL: Abbott Laboratories; 2002
    • (2002) Humira [Package Insert]
  • 60
    • 69549107572 scopus 로고    scopus 로고
    • Population pharmacokinetics of golimumab, an anti-tumor necrosis factor-a human monoclonal antibody, in patients with psoriatic arthritis
    • Xu Z, Vu T, Lee H, Hu C, Ling J, et al. 2009. Population pharmacokinetics of golimumab, an anti-tumor necrosis factor-a human monoclonal antibody, in patients with psoriatic arthritis. J. Clin. Pharmacol. 49:1056-70
    • (2009) J. Clin. Pharmacol. , vol.49 , pp. 1056-70
    • Xu, Z.1    Vu, T.2    Lee, H.3    Hu, C.4    Ling, J.5
  • 62
    • 10044271092 scopus 로고    scopus 로고
    • 2 integrin receptor expression by monocytes and neutrophils in rheumatoid arthritis: Interaction with platelets
    • M p2 integrin receptor expression by monocytes and neutrophils in rheumatoid arthritis: interaction with platelets. J. Rheumatol. 31:2347-55 (Pubitemid 39603080)
    • (2004) Journal of Rheumatology , vol.31 , Issue.12 , pp. 2347-2355
    • Bunescu, A.1    Seideman, P.2    Lenkei, R.3    Levin, K.4    Egberg, N.5
  • 63
    • 6344284247 scopus 로고    scopus 로고
    • Unaltered etanercept pharmacokinetics with concurrent methotrexate in patients with rheumatoid arthritis
    • DOI 10.1177/0091270004268049
    • Zhou H, Mayer PR, Wajdula J, Fatenejad S. 2004. Unaltered etanercept pharmacokinetics with concurrent methotrexate in patients with rheumatoid arthritis. J. Clin. Pharmacol. 44:1235-43 (Pubitemid 39391482)
    • (2004) Journal of Clinical Pharmacology , vol.44 , Issue.11 , pp. 1235-1243
    • Zhou, H.1    Mayer, P.R.2    Wajdula, J.3    Fatenejad, S.4
  • 66
    • 0029588451 scopus 로고
    • Reduced human IgG anti-ATGAM antibody formation in renal transplant recipients receiving mycophenolate mofetil
    • Kimball JA, Pescovitz MD, Book BK, Norman DJ. 1995. Reduced human IgG anti-ATGAM antibody formation in renal transplant recipients receiving mycophenolate mofetil. Transplantation 60:1379-83 (Pubitemid 26018420)
    • (1995) Transplantation , vol.60 , Issue.12 , pp. 1379-1383
    • Kimball, J.A.1    Pescovitz, M.D.2    Book, B.K.3    Norman, D.J.4
  • 69
    • 79951961155 scopus 로고    scopus 로고
    • Herceptin® [package insert]. San Francisco: Genentech Inc.; 2003
    • Herceptin® [package insert]. San Francisco: Genentech Inc.; 2003
  • 71
    • 0346017700 scopus 로고    scopus 로고
    • Pharmacokinetics, safety, and efficacy of trastuzumab administered every three weeks in combination with paclitaxel
    • DOI 10.1200/JCO.2003.12.109
    • Leyland-Jones B, Gelmon K, Ayoub JP, Arnold A, Verma S. 2003. Pharmacokinetics, safety, and efficacy of trastuzumab administered every three weeks in combination with paclitaxel. J. Clin. Oncol. 21:3965-71 (Pubitemid 46606210)
    • (2003) Journal of Clinical Oncology , vol.21 , Issue.21 , pp. 3965-3971
    • Leyland-Jones, B.1    Gelmon, K.2    Ayoub, J.-P.3    Arnold, A.4    Verma, S.5    Dias, R.6    Ghahramani, P.7
  • 72
    • 0037180939 scopus 로고    scopus 로고
    • The antineoplastic drug paclitaxel has immunosuppressive properties that can effectively promote allograft survival in a rat heart transplant model
    • Tange S, Scherer MN, Graeb C, Weiss T, Justl M, et al. 2002. The antineoplastic drug paclitaxel has immunosuppressive properties that can effectively promote allograft survival in a rat heart transplant model. Transplantation 73:216-23 (Pubitemid 34112843)
    • (2002) Transplantation , vol.73 , Issue.2 , pp. 216-223
    • Tange, S.1    Scherer, M.N.2    Graeb, C.3    Weiss, T.4    Justl, M.5    Frank, E.6    Andrassy, J.7    Jauch, K.-W.8    Geissler, E.K.9
  • 73
    • 77955283683 scopus 로고    scopus 로고
    • Trastuzumab pharmacokinetics influenced by extent human epidermal growth factor receptor 2-positive tumor load
    • Oude Munnink TH, Dijkers EC, Netters SJ, Lub-de Hooge MN, Brouwers AH, et al. 2010. Trastuzumab pharmacokinetics influenced by extent human epidermal growth factor receptor 2-positive tumor load. J. Clin. Oncol. 28:e355-56
    • (2010) J. Clin. Oncol. , vol.28
    • Oude Munnink, T.H.1    Dijkers, E.C.2    Netters, S.J.3    Lub-De Hooge, M.N.4    Brouwers, A.H.5
  • 74
    • 0029891262 scopus 로고    scopus 로고
    • The protection receptor for IgG catabolism is the β2-microglobulin- containing neonatal intestinal transport receptor
    • Junghans RP, Anderson CL. 1996. The protection receptor for IgG catabolism is the β2-microglobulin-containing neonatal intestinal transport receptor. Proc. Natl. Acad. Sci. USA 93:5512-16
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 5512-16
    • Junghans, R.P.1    Anderson, C.L.2
  • 75
    • 33746290180 scopus 로고    scopus 로고
    • Rituximab, bevacizumab and CHOP (RA-CHOP) in untreated diffuse large B-cell lymphoma: Safety, biomarker and pharmacokinetic analysis
    • Ganjoo KN, An CS, Robertson MJ, Gordon LI, Sen JA, et al. 2006. Rituximab, bevacizumab and CHOP (RA-CHOP) in untreated diffuse large B-cell lymphoma: safety, biomarker and pharmacokinetic analysis. Leukemia Lymphoma 47:998-1005
    • (2006) Leukemia Lymphoma , vol.47 , pp. 998-1005
    • Ganjoo, K.N.1    An, C.S.2    Robertson, M.J.3    Gordon, L.I.4    Sen, J.A.5
  • 76
  • 77
    • 0037105368 scopus 로고    scopus 로고
    • Effects of intravenous immunoglobulin on platelet count and antiplatelet antibody disposition in a rat model of immune thrombocytopenia
    • Hansen RJ, Balthasar JP. 2002. Effects of intravenous immunoglobulin on platelet count and antiplatelet antibody disposition in a rat model of immune thrombocytopenia. Blood 100:2087-93 (Pubitemid 35001242)
    • (2002) Blood , vol.100 , Issue.6 , pp. 2087-2093
    • Hansen, R.J.1    Balthasar, J.P.2


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