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Volumn 47, Issue 6, 2006, Pages 998-1005

Rituximab, Bevacizumab and CHOP (RA-CHOP) in untreated diffuse large B-cell lymphoma: Safety, biomarker and pharmacokinetic analysis

Author keywords

Anti angiogenesis; Bevacizumab; Diffuse large B cell lymphoma; Micro vessel density; Non Hodgkin's lymphoma; Rituximab; Vascular endothelial growth factor

Indexed keywords

AMINOTRANSFERASE; BEVACIZUMAB; BIOLOGICAL MARKER; BLOOD CLOTTING FACTOR 8; CD31 ANTIGEN; CYCLOPHOSPHAMIDE; DOXORUBICIN; PREDNISONE; RITUXIMAB; VASCULOTROPIN; VASCULOTROPIN A; VINCRISTINE;

EID: 33746290180     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.1080/10428190600563821     Document Type: Article
Times cited : (101)

References (37)
  • 1
    • 0027394689 scopus 로고
    • Comparison of a standard regimen (CHOP) with three intensive chemotherapy regimens for advanced non-Hodgkin's lymphoma
    • Fisher, R and Gaynor, E and Dahlberg, S and Oken, M and Grogan, T and Mize, E and et al. (1993) Comparison of a standard regimen (CHOP) with three intensive chemotherapy regimens for advanced non-Hodgkin's lymphoma N Eng J Med, 328, pp. 1002-1006.
    • (1993) N Eng J Med , vol.328 , pp. 1002-1006
    • Fisher, R.1    Gaynor, E.2    Dahlberg, S.3    Oken, M.4    Grogan, T.5    Mize, E.6
  • 2
    • 0026760539 scopus 로고
    • Comparison of a second generation combination chematherapeutic regimen (m-BACOD) with a standard regimen (CHOP) for advanced non-Hodgkin's lymphoma
    • Gordon, L and Harrington, D and Anderson, J and Colgan, J and Glick, J and Neiman, R and et al. (1991) Comparison of a second generation combination chematherapeutic regimen (m-BACOD) with a standard regimen (CHOP) for advanced non-Hodgkin's lymphoma N Eng J Med, 327, pp. 1342-1349.
    • (1991) N Eng J Med , vol.327 , pp. 1342-1349
    • Gordon, L.1    Harrington, D.2    Anderson, J.3    Colgan, J.4    Glick, J.5    Neiman, R.6
  • 3
    • 0037165261 scopus 로고    scopus 로고
    • CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large B-cell lymphoma
    • Coiffier, B and Lepage, E and Briere, J and Herbrecht, R and Tilly, H and Bouabdallah, R and et al. (2002) CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large B-cell lymphoma N Eng J Med, 346, pp. 235-242.
    • (2002) N Eng J Med , vol.346 , pp. 235-242
    • Coiffier, B.1    Lepage, E.2    Briere, J.3    Herbrecht, R.4    Tilly, H.5    Bouabdallah, R.6
  • 4
    • 13644249821 scopus 로고    scopus 로고
    • Rituximab-CHOP versus CHOP with or without maintenance rituximab in patients 60 years of age or older with diffuse large B-cell lymphoma (DLBCL): An update
    • Habermann, T and Weller, E and Morrison, V and Cassileth, P and Cohn, J and Dakhil, S and et al. (2004) Rituximab-CHOP versus CHOP with or without maintenance rituximab in patients 60 years of age or older with diffuse large B-cell lymphoma (DLBCL): An update Blood, 104.
    • (2004) Blood , pp. 104
    • Habermann, T.1    Weller, E.2    Morrison, V.3    Cassileth, P.4    Cohn, J.5    Dakhil, S.6
  • 5
    • 16244408186 scopus 로고    scopus 로고
    • First analysis of the completed Mabthera International (Mint) trial in young patients with low-risk diffuse large B-cell lymphoma (DLBCL)
    • Pfreundschuh, M and Truemper, L and Gill, D and Osterborg, A and Pettengell, R and Trneny, M and et al. (2004) First analysis of the completed Mabthera International (Mint) trial in young patients with low-risk diffuse large B-cell lymphoma (DLBCL) Blood, 104, pp. 157.
    • (2004) Blood , vol.104 , pp. 157
    • Pfreundschuh, M.1    Truemper, L.2    Gill, D.3    Osterborg, A.4    Pettengell, R.5    Trneny, M.6
  • 6
    • 0034548821 scopus 로고    scopus 로고
    • Simultaneous elevation in the serum concentration of the angiogenic growth factors and bFGF is an independent predictor of poor prognosis in non-Hodgkin's lymphoma: A single-institution study of 200 patients
    • Salven, P and Orpana, A and Teerenhovi, L and Joensuu, H and et al. (2000) Simultaneous elevation in the serum concentration of the angiogenic growth factors and bFGF is an independent predictor of poor prognosis in non-Hodgkin's lymphoma: A single-institution study of 200 patients Blood, 96, pp. 3712-3718.
    • (2000) Blood , vol.96 , pp. 3712-3718
    • Salven, P.1    Orpana, A.2    Teerenhovi, L.3    Joensuu, H.4
  • 7
    • 0034730186 scopus 로고    scopus 로고
    • Ongoing immunoglobulin somatic mutation in germinal center B cell-like but not in activated B cell-like diffuse large cell lymphomas
    • Lossos, I and Alizadeh, A and Eisen, M and Chan, W and Brown, P and Botstein, D and et al. (2000) Ongoing immunoglobulin somatic mutation in germinal center B cell-like but not in activated B cell-like diffuse large cell lymphomas Proceedings of the National Academy of Sciences (USA), 97, pp. 10209-10213.
    • (2000) Proceedings of the National Academy of Sciences (USA) , vol.97 , pp. 10209-10213
    • Lossos, I.1    Alizadeh, A.2    Eisen, M.3    Chan, W.4    Brown, P.5    Botstein, D.6
  • 8
    • 0242550768 scopus 로고    scopus 로고
    • Prognostic significance of microvessel density and vascular endothelial growth factor (VEGF) expression in non-Hodgkin's lymphoma
    • Hazar, B and Paydas, S and Zorludemir, S and Sahin, B and Tuncer, I and et al. (2003) Prognostic significance of microvessel density and vascular endothelial growth factor (VEGF) expression in non-Hodgkin's lymphoma Leukemia & Lymphoma, 44, pp. 2089-2093.
    • (2003) Leukemia & Lymphoma , vol.44 , pp. 2089-2093
    • Hazar, B.1    Paydas, S.2    Zorludemir, S.3    Sahin, B.4    Tuncer, I.5
  • 9
    • 3142767799 scopus 로고    scopus 로고
    • Lymphoma-specific genetic aberrations in microvascular endothelial cells in B-cell lymphomas
    • Strebel, B and Chott, A and Huber, D and Exner, M and Jager, U and Wagner, O and et al. (2004) Lymphoma-specific genetic aberrations in microvascular endothelial cells in B-cell lymphomas N Eng J Med, 351, pp. 250-259.
    • (2004) N Eng J Med , vol.351 , pp. 250-259
    • Strebel, B.1    Chott, A.2    Huber, D.3    Exner, M.4    Jager, U.5    Wagner, O.6
  • 10
    • 0035885932 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) is an autocrine growth factor for VEGF receptor-positive human tumors
    • Masood, R and Cai, J and Zheng, T and Smith, D and Hinton, D and Gill, P and et al. (2001) Vascular endothelial growth factor (VEGF) is an autocrine growth factor for VEGF receptor-positive human tumors Blood, 98, pp. 1904-1913.
    • (2001) Blood , vol.98 , pp. 1904-1913
    • Masood, R.1    Cai, J.2    Zheng, T.3    Smith, D.4    Hinton, D.5    Gill, P.6
  • 11
    • 7244236494 scopus 로고    scopus 로고
    • Targeting autocrine and paracrine VEGF receptor pathways inhibits human lymphoma xenografts in vivo
    • Wang, E and Teruya-Feldstein, J and Wu, Y and Zhu, Z and Hicklin, D and Moore, M and et al. (2004) Targeting autocrine and paracrine VEGF receptor pathways inhibits human lymphoma xenografts in vivo Blood, 104, pp. 2893-2902.
    • (2004) Blood , vol.104 , pp. 2893-2902
    • Wang, E.1    Teruya-Feldstein, J.2    Wu, Y.3    Zhu, Z.4    Hicklin, D.5    Moore, M.6
  • 12
    • 33947226602 scopus 로고    scopus 로고
    • Expression of VEGF, VEGF receptors, and other angiogenic markers in relapsed aggressive non-Hodgkin's lymphoma: Correlative studies from the SWOG S0108 trial
    • abst
    • Stopeck, A and Iannone, M and Rimsza, L and Miller, T and Fisher, R and Bellamy, W and et al. (2004) Expression of VEGF, VEGF receptors, and other angiogenic markers in relapsed aggressive non-Hodgkin's lymphoma: correlative studies from the SWOG S0108 trial Blood, 104. abst 2288
    • (2004) Blood , vol.104 , pp. 2288
    • Stopeck, A.1    Iannone, M.2    Rimsza, L.3    Miller, T.4    Fisher, R.5    Bellamy, W.6
  • 13
    • 0030856731 scopus 로고    scopus 로고
    • Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders
    • Presta, L and Chen, H and O'Connor, S and Chisholm, V and Meng, Y and Krummen, L and et al. (1997) Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders Cancer Res, 57, pp. 4593-4599.
    • (1997) Cancer Res , vol.57 , pp. 4593-4599
    • Presta, L.1    Chen, H.2    O'Connor, S.3    Chisholm, V.4    Meng, Y.5    Krummen, L.6
  • 14
    • 0032979775 scopus 로고    scopus 로고
    • Preclinical safety evaluation of bevacizumab, an antiangiogenic humanized monoclonal antibody
    • Ryan, A and Eppler, D and Hagler, K and Bruner, R and Thomford, P and Hall, R and et al. (1999) Preclinical safety evaluation of bevacizumab, an antiangiogenic humanized monoclonal antibody Toxicol Pathol, 27, pp. 78-86.
    • (1999) Toxicol Pathol , vol.27 , pp. 78-86
    • Ryan, A.1    Eppler, D.2    Hagler, K.3    Bruner, R.4    Thomford, P.5    Hall, R.6
  • 15
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus Irinotecan, Fluorouracil, and Leucovorin for metastatic colorectal cancer
    • Hurwitz, H and Fehrenbacher, L and Novotny, W and Cartwright, T and Hainsworth, J and Heim, W and et al. (2004) Bevacizumab plus Irinotecan, Fluorouracil, and Leucovorin for metastatic colorectal cancer N Eng J Med, 350, pp. 2335-2342.
    • (2004) N Eng J Med , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3    Cartwright, T.4    Hainsworth, J.5    Heim, W.6
  • 16
    • 22144471081 scopus 로고    scopus 로고
    • Randomized phase II/III trial of paclitaxel (P) plus carboplatin (C) with or without bevacizumab (NSC #704865) in patients with advanced non-squamous non small cell lung cancer (NSCLC): An Eastern Cooperative Oncology Group (ECOG) Trial E4599
    • Abst# LBA4
    • Sandler, A and Gray, R and Brahmer, J and Dowlati, A and Schiller, J and Perry, M and et al. (2005) Randomized phase II/III trial of paclitaxel (P) plus carboplatin (C) with or without bevacizumab (NSC #704865) in patients with advanced non-squamous non small cell lung cancer (NSCLC): an Eastern Cooperative Oncology Group (ECOG) Trial E4599 Proc of ASCO. Abst# LBA4
    • (2005) Proc of ASCO
    • Sandler, A.1    Gray, R.2    Brahmer, J.3    Dowlati, A.4    Schiller, J.5    Perry, M.6
  • 17
    • 33646780432 scopus 로고    scopus 로고
    • E2100: A randomized phase III trial of paclitaxel versus paclitaxel plus bevacizumab as first-line therapy for locally recurrent or metastatic breast cancer
    • Miller, K and Wang, M and Gralow, J and et al. (2005) E2100: A randomized phase III trial of paclitaxel versus paclitaxel plus bevacizumab as first-line therapy for locally recurrent or metastatic breast cancer Proc of ASCO.
    • (2005) Proc of ASCO
    • Miller, K.1    Wang, M.2    Gralow, J.3
  • 18
    • 21244481589 scopus 로고    scopus 로고
    • High-dose bevacizumab improves survival when combined with FOLFOX4 in previously treated advanced colorectal cancer: Results from the Eastern Cooperative Oncology Group (ECOG) study E3200
    • Abst# 2
    • Giantonio, B and Catalano, P and Meropol, N and O'Dwyer, P and Mitchell, E and Alberts, M and et al. (2005) High-dose bevacizumab improves survival when combined with FOLFOX4 in previously treated advanced colorectal cancer: Results from the Eastern Cooperative Oncology Group (ECOG) study E3200 Proc of ASCO. Abst# 2
    • (2005) Proc of ASCO
    • Giantonio, B.1    Catalano, P.2    Meropol, N.3    O'Dwyer, P.4    Mitchell, E.5    Alberts, M.6
  • 19
    • 0029127219 scopus 로고
    • Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors. breast
    • Weidner. (1995) Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors. breast Breast Cancer Res Treat, 36, pp. 169-180.
    • (1995) Breast Cancer Res Treat , vol.36 , pp. 169-180
    • Weidner1
  • 20
    • 0034650418 scopus 로고    scopus 로고
    • Angiogenesis and mast cell density with tryptase activity increase simultaneously with pathological progression in B-cell non-Hodgkin's lymphomas
    • Ribatti, D and Vacca, A and Marzullo, A and Nico, B and Ria, R and Roncali, L and Dammacco, F. (2000) Angiogenesis and mast cell density with tryptase activity increase simultaneously with pathological progression in B-cell non-Hodgkin's lymphomas Int J Cancer, 85, pp. 171-175.
    • (2000) Int J Cancer , vol.85 , pp. 171-175
    • Ribatti, D.1    Vacca, A.2    Marzullo, A.3    Nico, B.4    Ria, R.5    Roncali, L.6    Dammacco, F.7
  • 23
    • 27744462241 scopus 로고    scopus 로고
    • Plasma concentrations of vascular endothelial growth factor and basic fibroblast growth factor in lymphoproliferative disorders
    • Smolej, L and Andrys, C and Maisnar, V and Pour, L and Maly, J and et al. (2005) Plasma concentrations of vascular endothelial growth factor and basic fibroblast growth factor in lymphoproliferative disorders Acta Medica, 48, pp. 57-58.
    • (2005) Acta Medica , vol.48 , pp. 57-58
    • Smolej, L.1    Andrys, C.2    Maisnar, V.3    Pour, L.4    Maly, J.5
  • 24
    • 5344257527 scopus 로고    scopus 로고
    • Prognostic significance of vascular endothelial growth factor immunoexpression in the context of adverse standard prognostic factors in multiple myeloma
    • Ribas, C and Colleoni, G and Silva, M and Carregoza, M and Bordin, Jo and et al. (2004) Prognostic significance of vascular endothelial growth factor immunoexpression in the context of adverse standard prognostic factors in multiple myeloma Eur J Haemotol, 73, pp. 311-317.
    • (2004) Eur J Haemotol , vol.73 , pp. 311-317
    • Ribas, C.1    Colleoni, G.2    Silva, M.3    Carregoza, M.4    Bordin, Jo.5
  • 25
    • 22344457663 scopus 로고    scopus 로고
    • Early changes in serum IL-6 and VEGF levels predict clinical outcome following first-line therapy in aggressive non-Hodgkin's lymphoma
    • Pedersen, L and Klausen, T and Davidsen, U and Johnsen, H and et al. (2005) Early changes in serum IL-6 and VEGF levels predict clinical outcome following first-line therapy in aggressive non-Hodgkin's lymphoma Ann Hemat, 84, pp. 510-516.
    • (2005) Ann Hemat , vol.84 , pp. 510-516
    • Pedersen, L.1    Klausen, T.2    Davidsen, U.3    Johnsen, H.4
  • 26
    • 0032748385 scopus 로고    scopus 로고
    • Antitumor activity of thalidomide in refractory multiple myeloma
    • Singhal, S and Mehta, J and Desikan, R and Ayers, D and Roberson, P and Eddlemon, P and et al. (1999) Antitumor activity of thalidomide in refractory multiple myeloma N Eng J Med, 341, pp. 1565.
    • (1999) N Eng J Med , vol.341 , pp. 1565
    • Singhal, S.1    Mehta, J.2    Desikan, R.3    Ayers, D.4    Roberson, P.5    Eddlemon, P.6
  • 27
    • 17044393376 scopus 로고    scopus 로고
    • The influence of thalidomide therapy on cytokine secretion, immunophenotype, BCL-2 expression and microvessel density in patients with resistant or relapsed multiple myeloma
    • Dmoszynska, A and Podhorecka, M and Manko, J and Bojarska-Junak, A and Rolinski, J and Skomra, D and et al. (2005) The influence of thalidomide therapy on cytokine secretion, immunophenotype, BCL-2 expression and microvessel density in patients with resistant or relapsed multiple myeloma Neoplasm, 52, pp. 175-181.
    • (2005) Neoplasm , vol.52 , pp. 175-181
    • Dmoszynska, A.1    Podhorecka, M.2    Manko, J.3    Bojarska-Junak, A.4    Rolinski, J.5    Skomra, D.6
  • 28
    • 8344254359 scopus 로고    scopus 로고
    • Vascular endothelial growth factor- A in expressed both on lymphoma cells and endothelial cells in angioimmunoblastic T-cell lymphoma and related to lymphoma progression
    • Zhao, W and Mourah, S and Mounier, N and Leboeuf, C and Daneshpouy, M and Legres, L and et al. (2004) Vascular endothelial growth factor- A in expressed both on lymphoma cells and endothelial cells in angioimmunoblastic T-cell lymphoma and related to lymphoma progression Laboratory Investigations, 84, pp. 1512-1519.
    • (2004) Laboratory Investigations , vol.84 , pp. 1512-1519
    • Zhao, W.1    Mourah, S.2    Mounier, N.3    Leboeuf, C.4    Daneshpouy, M.5    Legres, L.6
  • 29
    • 4143136640 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: Basic science and clinical progress
    • Ferrara, N. (2004) Vascular endothelial growth factor: Basic science and clinical progress Endocrinol Rev, 25, pp. 581-611.
    • (2004) Endocrinol Rev , vol.25 , pp. 581-611
    • Ferrara, N.1
  • 30
    • 0029047695 scopus 로고
    • Vascular permeability factor/vascular endothelial growth factor: An important mediator of angiogenesis in malignancy and inflammation
    • Dvorak, H and Detmar, M and Claffey, K and Nagy, J and Van de Water, L and Senger, D and et al. (1995) Vascular permeability factor/vascular endothelial growth factor: An important mediator of angiogenesis in malignancy and inflammation Inter Arch Allergy Immunol, 107, pp. 233-235.
    • (1995) Inter Arch Allergy Immunol , vol.107 , pp. 233-235
    • Dvorak, H.1    Detmar, M.2    Claffey, K.3    Nagy, J.4    Van de Water, L.5    Senger, D.6
  • 31
    • 0036900804 scopus 로고    scopus 로고
    • Immunohistochemical expression of Basic fibroblast growth factor, vascular endothelial growth factor, and their receptors in stage IV non-Hodgkin's lymphoma
    • Ho, C and Sheu, L and Li, C and et al. (2002) Immunohistochemical expression of Basic fibroblast growth factor, vascular endothelial growth factor, and their receptors in stage IV non-Hodgkin's lymphoma Applied Immunohistochemistry and Molecular Morphology, 10, pp. 316-321.
    • (2002) Applied Immunohistochemistry and Molecular Morphology , vol.10 , pp. 316-321
    • Ho, C.1    Sheu, L.2    Li, C.3
  • 32
    • 0036251241 scopus 로고    scopus 로고
    • Simultaneous elevation of the serum concentration of vascular endothelial growth factor and interleukin-6 as independent predictors of prognosis in aggressive non-Hodgkin's lymphoma
    • Niitsu, N and Okamoto, M and Nakamine, H and Yoshino, T and Tamaru, J and Nakamura, S and et al. (2004) Simultaneous elevation of the serum concentration of vascular endothelial growth factor and interleukin-6 as independent predictors of prognosis in aggressive non-Hodgkin's lymphoma Eur J Haematol, 68, pp. 91-100.
    • (2004) Eur J Haematol , vol.68 , pp. 91-100
    • Niitsu, N.1    Okamoto, M.2    Nakamine, H.3    Yoshino, T.4    Tamaru, J.5    Nakamura, S.6
  • 33
    • 0031946469 scopus 로고    scopus 로고
    • Magnetic resonance imaging detects suppression of tumor vascular permeability after administration of antibody to vascular endothelial growth factor
    • Pham, C and Roberts, T and van Bruggen, N and Melnyk, O and Mann, J and Ferrara, N and et al. (1998) Magnetic resonance imaging detects suppression of tumor vascular permeability after administration of antibody to vascular endothelial growth factor Cancer Invest, 16, pp. 225-230.
    • (1998) Cancer Invest , vol.16 , pp. 225-230
    • Pham, C.1    Roberts, T.2    van Bruggen, N.3    Melnyk, O.4    Mann, J.5    Ferrara, N.6
  • 34
    • 0035253586 scopus 로고    scopus 로고
    • Phase Ib trial of intravenous recombinant humanized monoclonal antibody to vascular endothelial growth factor in combination with chemotherapy in patients with advanced cancer: Pharmacologic and long-term safety data
    • Margolin, K and Gordon, M and Holmgren, E and Gaudreault, J and Novotny, W and Fyfe, G and et al. (2001) Phase Ib trial of intravenous recombinant humanized monoclonal antibody to vascular endothelial growth factor in combination with chemotherapy in patients with advanced cancer: Pharmacologic and long-term safety data J Clin Oncol, 19, pp. 851-856.
    • (2001) J Clin Oncol , vol.19 , pp. 851-856
    • Margolin, K.1    Gordon, M.2    Holmgren, E.3    Gaudreault, J.4    Novotny, W.5    Fyfe, G.6
  • 35
    • 0035253739 scopus 로고    scopus 로고
    • Phase I safety and pharmacokinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer
    • Gordon, M and Margolin, K and Talpaz, M and Sledge, G, Jr and Holmgren, E and Benjamin, R and et al. (2001) Phase I safety and pharmacokinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer J Clin Oncol, 19, pp. 843-845.
    • (2001) J Clin Oncol , vol.19 , pp. 843-845
    • Gordon, M.1    Margolin, K.2    Talpaz, M.3    Sledge Jr., G.4    Holmgren, E.5    Benjamin, R.6
  • 36
    • 27644439175 scopus 로고    scopus 로고
    • Phase II trial of single agent bevacizumab in patients with relapsed, aggressive non-Hodgkin's lymphoma (NHL): Southwest Oncology Group Study S0108
    • abst #6592
    • Stopeck, A and Bellamy, W and Unger, J and Rimsza, L and Iannone, M and Fisher, R and et al. (2005) Phase II trial of single agent bevacizumab in patients with relapsed, aggressive non-Hodgkin's lymphoma (NHL): Southwest Oncology Group Study S0108 Proc of ASCO. abst #6592
    • (2005) Proc of ASCO
    • Stopeck, A.1    Bellamy, W.2    Unger, J.3    Rimsza, L.4    Iannone, M.5    Fisher, R.6
  • 37
    • 20244381389 scopus 로고    scopus 로고
    • Phase I/II trial evaluating the anti-vascular endothelial growth factor monoclonal antibody bevacizumab in combination with the HER-1/epidermal growth factor receptor tyrosine kinase inhibitor erlotinib for patients with recurrent non-small cell lung cancer
    • Herbst, R and Johnson, D and Mininberg, E and Carbone, D and Henderson, T and Kim, E and et al. (2005) Phase I/II trial evaluating the anti-vascular endothelial growth factor monoclonal antibody bevacizumab in combination with the HER-1/epidermal growth factor receptor tyrosine kinase inhibitor erlotinib for patients with recurrent non-small cell lung cancer J Clin Oncol, 23, pp. 1-10.
    • (2005) J Clin Oncol , vol.23 , pp. 1-10
    • Herbst, R.1    Johnson, D.2    Mininberg, E.3    Carbone, D.4    Henderson, T.5    Kim, E.6


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