BONE METASTASIS;
BRAIN METASTASIS;
BREAST CANCER;
DOSE RESPONSE;
DRUG BLOOD LEVEL;
DRUG CLEARANCE;
DRUG EFFICACY;
DRUG HALF LIFE;
DRUG SAFETY;
FEMALE;
HUMAN;
LETTER;
LIVER METASTASIS;
LOADING DRUG DOSE;
METASTASIS;
PLASMA CONCENTRATION-TIME CURVE;
POSITRON EMISSION TOMOGRAPHY;
PRIORITY JOURNAL;
STEADY STATE;
BREAST TUMOR;
CHEMISTRY;
NOTE;
FDA clinical review of BLA 98-0369: Herceptin trastuzumab (rhuMAb HER2). http://www.fda.gov/downloads/Drugs/DevelopmentApprovalProcess/ HowDrugsareDevelopedandApproved/ApprovalApplications/ TherapeuticBiologicApplications/ucm091373.pdf
Population pharmacokinetics of trastuzumab in patients with HER2+ metastatic breast cancer
DOI 10.1007/s00280-005-1026-z
Bruno R, Washington CB, Lu JF, et al: Population pharmacokinetics of trastuzumab in patients with HER2+ metastatic breast cancer. Cancer Chemother Pharmacol 56:361-369, 2005 (Pubitemid 41095399)
89Zr-trastuzumab biodistribution and HER2 PET imaging in metastatic breast cancer patients
doi: 10.1038/clpt.2010.12 epub ahead of print on March 31
89Zr- trastuzumab biodistribution and HER2 PET imaging in metastatic breast cancer patients. Clin Pharmacol Ther doi: 10.1038/clpt.2010.12 (epub ahead of print on March 31, 2010)
The molecular and cellular biology of HER2/neu gene amplification/ overexpression and the clinical development of herceptin (trastuzumab) therapy for breast cancer
Pegram MD, Konecny G, Slamon DJ: The molecular and cellular biology of HER2/neu gene amplification/overexpression and the clinical development of herceptin (trastuzumab) therapy for breast cancer. Cancer Treat Res 103:57-75, 2000