-
1
-
-
0019423856
-
Sequence and organization of the human mitochondrial genome
-
Anderson, S., Bankier, A.T., Barrell, B.G., de Bruijn, M.H., Coulson, A.R., Drouin, J., Eperon, I.C., Nierlich, D.P., Roe, B.A., Sanger, F. et al. (1981) Sequence and organization of the human mitochondrial genome. Nature 290, 457-465
-
(1981)
Nature
, vol.290
, pp. 457-465
-
-
Anderson, S.1
Bankier, A.T.2
Barrell, B.G.3
De Bruijn, M.H.4
Coulson, A.R.5
Drouin, J.6
Eperon, I.C.7
Nierlich, D.P.8
Roe, B.A.9
Sanger, F.10
-
2
-
-
0032868141
-
Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA
-
Andrews, R.M., Kubacka, I., Chinnery, P.F., Lightowlers, R.N., Turnbull, D.M. and Howell, N. (1999) Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA. Nat. Genet. 23, 147
-
(1999)
Nat. Genet
, vol.23
, pp. 147
-
-
Andrews, R.M.1
Kubacka, I.2
Chinnery, P.F.3
Lightowlers, R.N.4
Turnbull, D.M.5
Howell, N.6
-
3
-
-
34548627532
-
DNA replication and transcription in mammalian mitochondria
-
Falkenberg, M., Larsson, N.G. and Gustafsson, C.M. (2007) DNA replication and transcription in mammalian mitochondria. Annu. Rev. Biochem. 76, 679-699
-
(2007)
Annu. Rev. Biochem
, vol.76
, pp. 679-699
-
-
Falkenberg, M.1
Larsson, N.G.2
Gustafsson, C.M.3
-
4
-
-
41249098355
-
The layered structure of human mitochondrial DNA nucleoids
-
Bogenhagen, D.F., Rousseau, D. and Burke, S. (2008) The layered structure of human mitochondrial DNA nucleoids. J. Biol. Chem. 283, 3665-3675
-
(2008)
J. Biol. Chem
, vol.283
, pp. 3665-3675
-
-
Bogenhagen, D.F.1
Rousseau, D.2
Burke, S.3
-
5
-
-
0015106989
-
Symbiosis and evolution
-
Margulis, L. (1971) Symbiosis and evolution. Sci. Am. 225, 48-57
-
(1971)
Sci. Am.
, vol.225
, pp. 48-57
-
-
Margulis, L.1
-
6
-
-
0022532186
-
Why mitochondria need a genome
-
von Heijne, G. (1986) Why mitochondria need a genome. FEBS Lett. 198, 1-4
-
(1986)
FEBS Lett
, vol.198
, pp. 1-4
-
-
Von Heijne, G.1
-
7
-
-
66449103627
-
Do organellar genomes function as long-term redox damage sensors?
-
Wright, A.F., Murphy, M.P. and Turnbull, D.M. (2009) Do organellar genomes function as long-term redox damage sensors? Trends Genet. 25, 253-261
-
(2009)
Trends Genet
, vol.25
, pp. 253-261
-
-
Wright, A.F.1
Murphy, M.P.2
Turnbull, D.M.3
-
8
-
-
0019978703
-
Replication of animal mitochondrial DNA
-
Clayton, D.A. (1982) Replication of animal mitochondrial DNA. Cell 28, 693-705
-
(1982)
Cell
, vol.28
, pp. 693-705
-
-
Clayton, D.A.1
-
9
-
-
0034598918
-
Coupled leading- and lagging-strand synthesis of mammalian mitochondrial DNA
-
Holt, I.J., Lorimer, H.E. and Jacobs, H.T. (2000) Coupled leading- and lagging-strand synthesis of mammalian mitochondrial DNA. Cell 100, 515-524
-
(2000)
Cell
, vol.100
, pp. 515-524
-
-
Holt, I.J.1
Lorimer, H.E.2
Jacobs, H.T.3
-
10
-
-
0037112343
-
Biased incorporation of ribonucleotides on the mitochondrial L-strand accounts for apparent strand-asymmetric DNA replication
-
Yang, M.Y., Bowmaker, M., Reyes, A., Vergani, L., Angeli, P., Gringeri, E., Jacobs, H.T. and Holt, I.J. (2002) Biased incorporation of ribonucleotides on the mitochondrial L-strand accounts for apparent strand-asymmetric DNA replication. Cell 111, 495-505
-
(2002)
Cell
, vol.111
, pp. 495-505
-
-
Yang, M.Y.1
Bowmaker, M.2
Reyes, A.3
Vergani, L.4
Angeli, P.5
Gringeri, E.6
Jacobs, H.T.7
Holt, I.J.8
-
11
-
-
33751088000
-
Replication of vertebrate mitochondrial DNA entails transient ribonucleotide incorporation throughout the lagging strand
-
Yasukawa, T., Reyes, A., Cluett, T.J., Yang, M.Y., Bowmaker, M., Jacobs, H.T. and Holt, I.J. (2006) Replication of vertebrate mitochondrial DNA entails transient ribonucleotide incorporation throughout the lagging strand. EMBO J. 25, 5358-5371
-
(2006)
EMBO J.
, vol.25
, pp. 5358-5371
-
-
Yasukawa, T.1
Reyes, A.2
Cluett, T.J.3
Yang, M.Y.4
Bowmaker, M.5
Jacobs, H.T.6
Holt, I.J.7
-
12
-
-
33749001168
-
Mitochondrial DNA polymerase-γ and human disease
-
Hudson, G. and Chinnery, P.F. (2006) Mitochondrial DNA polymerase-γ and human disease. Hum. Mol. Genet. 15 (Spec No 2), R244-R252
-
(2006)
Hum. Mol. Genet
, vol.15
, Issue.SPEC. NO. 2
-
-
Hudson, G.1
Chinnery, P.F.2
-
13
-
-
0026673872
-
DNA binding properties of an HMG1-related protein from yeast mitochondria
-
Diffley, J.F. and Stillman, B. (1992) DNA binding properties of an HMG1-related protein from yeast mitochondria. J. Biol. Chem. 267, 3368-3374
-
(1992)
J. Biol. Chem
, vol.267
, pp. 3368-3374
-
-
Diffley, J.F.1
Stillman, B.2
-
14
-
-
0000825475
-
The absence of a pyrimidine dimer repair mechanism in mammalian mitochondria
-
Clayton, D.A., Doda, J.N. and Friedberg, E.C. (1974) The absence of a pyrimidine dimer repair mechanism in mammalian mitochondria. Proc. Natl. Acad. Sci. U.S.A. 71, 2777-2781
-
(1974)
Proc. Natl. Acad. Sci. U.S.A.
, vol.71
, pp. 2777-2781
-
-
Clayton, D.A.1
Doda, J.N.2
Friedberg, E.C.3
-
15
-
-
0036570012
-
Repair of oxidative DNA damage in nuclear and mitochondrial DNA, and some changes with aging in mammalian cells
-
Bohr, V.A. (2002) Repair of oxidative DNA damage in nuclear and mitochondrial DNA, and some changes with aging in mammalian cells. Free Radical Biol. Med. 32, 804-812
-
(2002)
Free Radical Biol. Med
, vol.32
, pp. 804-812
-
-
Bohr, V.A.1
-
16
-
-
49449102611
-
Removal of oxidative DNA damage via FEN1-dependent long-patch base excision repair in human cell mitochondria
-
Liu, P., Qian, L., Sung, J.S., de Souza-Pinto, N.C., Zheng, L., Bogenhagen, D.F., Bohr, V.A., Wilson, 3rd, D.M., Shen, B., Demple, B. and Pinz, K.G. (2008) Removal of oxidative DNA damage via FEN1-dependent long-patch base excision repair in human cell mitochondria. Mol. Cell. Biol. 28, 4975-4987
-
(2008)
Mol. Cell. Biol
, vol.28
, pp. 4975-4987
-
-
Liu, P.1
Qian, L.2
Sung, J.S.3
De Souza-Pinto, N.C.4
Zheng, L.5
Bogenhagen, D.F.6
Bohr, V.A.7
Wilson Iii, D.M.8
Shen, B.9
Demple, B.10
Pinz, K.G.11
-
17
-
-
0037324321
-
Mismatch repair activity in mammalian mitochondria
-
Mason, P.A., Matheson, E.C., Hall, A.G. and Lightowlers, R.N. (2003) Mismatch repair activity in mammalian mitochondria. Nucleic Acids Res. 31, 1052-1058
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 1052-1058
-
-
Mason, P.A.1
Matheson, E.C.2
Hall, A.G.3
Lightowlers, R.N.4
-
18
-
-
0019495572
-
Synthesis and turnover of mitochondrial ribonucleic acid in HeLa cells: The mature ribosomal and messenger ribonucleic acid species are metabolically unstable
-
Gelfand, R. and Attardi, G. (1981) Synthesis and turnover of mitochondrial ribonucleic acid in HeLa cells: the mature ribosomal and messenger ribonucleic acid species are metabolically unstable. Mol. Cell. Biol. 1, 497-511
-
(1981)
Mol. Cell. Biol
, vol.1
, pp. 497-511
-
-
Gelfand, R.1
Attardi, G.2
-
19
-
-
65449130464
-
The MTERF family proteins: Mitochondrial transcription regulators and beyond
-
Roberti, M., Polosa, P.L., Bruni, F., Manzari, C., Deceglie, S., Gadaleta, M.N. and Cantatore, P. (2009) The MTERF family proteins: mitochondrial transcription regulators and beyond. Biochim. Biophys. Acta 1787, 303-311
-
(2009)
Biochim. Biophys. Acta
, vol.1787
, pp. 303-311
-
-
Roberti, M.1
Polosa, P.L.2
Bruni, F.3
Manzari, C.4
Deceglie, S.5
Gadaleta, M.N.6
Cantatore, P.7
-
20
-
-
0042632864
-
Human mitochondrial transcription factor B1 interacts with the C-terminal activation region of h-mtTFA and stimulates transcription independently of its RNA methyltransferase activity
-
McCulloch, V. and Shadel, G.S. (2003) Human mitochondrial transcription factor B1 interacts with the C-terminal activation region of h-mtTFA and stimulates transcription independently of its RNA methyltransferase activity. Mol. Cell. Biol. 23, 5816-5824
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 5816-5824
-
-
McCulloch, V.1
Shadel, G.S.2
-
21
-
-
63449105579
-
Methylation of 12S rRNA is necessary for in vivo stability of the small subunit of the mammalian mitochondrial ribosome
-
Metodiev, M.D., Lesko, N., Park, C.B., Camara, Y., Shi, Y., Wibom, R., Hultenby, K., Gustafsson, C.M. and Larsson, N.G. (2009) Methylation of 12S rRNA is necessary for in vivo stability of the small subunit of the mammalian mitochondrial ribosome. Cell. Metab. 9, 386-397
-
(2009)
Cell. Metab
, vol.9
, pp. 386-397
-
-
Metodiev, M.D.1
Lesko, N.2
Park, C.B.3
Camara, Y.4
Shi, Y.5
Wibom, R.6
Hultenby, K.7
Gustafsson, C.M.8
Larsson, N.G.9
-
22
-
-
54549088876
-
RNase P without RNA: Identification and functional reconstitution of the human mitochondrial tRNA processing enzyme
-
Holzmann, J., Frank, P., Loffler, E., Bennett, K.L., Gerner, C. and Rossmanith, W. (2008) RNase P without RNA: identification and functional reconstitution of the human mitochondrial tRNA processing enzyme. Cell 135, 462-474
-
(2008)
Cell
, vol.135
, pp. 462-474
-
-
Holzmann, J.1
Frank, P.2
Loffler, E.3
Bennett, K.L.4
Gerner, C.5
Rossmanith, W.6
-
23
-
-
36749030716
-
How do mammalian mitochondria synthesize proteins?
-
Rorbach, J., Soleimanpour-Lichaei, R., Lightowlers, R.N. and Chrzanowska-Lightowlers, Z.M. (2007) How do mammalian mitochondria synthesize proteins? Biochem. Soc. Trans. 35, 1290-1291
-
(2007)
Biochem. Soc. Trans
, vol.35
, pp. 1290-1291
-
-
Rorbach, J.1
Soleimanpour-Lichaei, R.2
Lightowlers, R.N.3
Chrzanowska- Lightowlers, Z.M.4
-
24
-
-
0034619822
-
Mitochondrial genome variation and the origin of modern humans
-
Ingman, M., Kaessmann, H., Paabo, S. and Gyllensten, U. (2000) Mitochondrial genome variation and the origin of modern humans. Nature 408, 708-713
-
(2000)
Nature
, vol.408
, pp. 708-713
-
-
Ingman, M.1
Kaessmann, H.2
Paabo, S.3
Gyllensten, U.4
-
25
-
-
44849139534
-
A functionally dominant mitochondrial DNA mutation
-
Sacconi, S., Salviati, L., Nishigaki, Y., Walker, W.F., Hernandez-Rosa, E., Trevisson, E., Delplace, S., Desnuelle, C., Shanske, S., Hirano, M. et al. (2008) A functionally dominant mitochondrial DNA mutation. Hum. Mol. Genet. 17, 1814-1820
-
(2008)
Hum. Mol. Genet
, vol.17
, pp. 1814-1820
-
-
Sacconi, S.1
Salviati, L.2
Nishigaki, Y.3
Walker, W.F.4
Hernandez-Rosa, E.5
Trevisson, E.6
Delplace, S.7
Desnuelle, C.8
Shanske, S.9
Hirano, M.10
-
26
-
-
48349097445
-
Pathogenic mitochondrial DNA mutations are common in the general population
-
Elliott, H.R., Samuels, D.C., Eden, J.A., Relton, C.L. and Chinnery, P.F. (2008) Pathogenic mitochondrial DNA mutations are common in the general population. Am. J. Hum. Genet. 83, 254-260
-
(2008)
Am. J. Hum. Genet
, vol.83
, pp. 254-260
-
-
Elliott, H.R.1
Samuels, D.C.2
Eden, J.A.3
Relton, C.L.4
Chinnery, P.F.5
-
27
-
-
59749088107
-
Prevalence of mitochondrial 1555A→G mutation in European children
-
Bitner-Glindzicz, M., Pembrey, M., Duncan, A., Heron, J., Ring, S.M., Hall, A. and Rahman, S. (2009) Prevalence of mitochondrial 1555A→G mutation in European children. N. Engl. J. Med. 360, 640-642
-
(2009)
N. Engl. J. Med
, vol.360
, pp. 640-642
-
-
Bitner-Glindzicz, M.1
Pembrey, M.2
Duncan, A.3
Heron, J.4
Ring, S.M.5
Hall, A.6
Rahman, S.7
-
28
-
-
59749096341
-
Prevalence of mitochondrial 1555A→G mutation in adults of European descent
-
Vandebona, H., Mitchell, P., Manwaring, N., Griffiths, K., Gopinath, B., Wang, J.J. and Sue, C.M. (2009) Prevalence of mitochondrial 1555A→G mutation in adults of European descent. N. Engl. J. Med. 360, 642-644
-
(2009)
N. Engl. J. Med
, vol.360
, pp. 642-644
-
-
Vandebona, H.1
Mitchell, P.2
Manwaring, N.3
Griffiths, K.4
Gopinath, B.5
Wang, J.J.6
Sue, C.M.7
-
29
-
-
39049156470
-
Prevalence of mitochondrial DNA disease in adults
-
Schaefer, A.M., McFarland, R., Blakely, E.L., He, L., Whittaker, R.G., Taylor, R.W., Chinnery, P.F. and Turnbull, D.M. (2008) Prevalence of mitochondrial DNA disease in adults. Ann. Neurol. 63, 35-39
-
(2008)
Ann. Neurol
, vol.63
, pp. 35-39
-
-
Schaefer, A.M.1
McFarland, R.2
Blakely, E.L.3
He, L.4
Whittaker, R.G.5
Taylor, R.W.6
Chinnery, P.F.7
Turnbull, D.M.8
-
30
-
-
33847248347
-
The mitochondrial bottleneck occurs without reduction of mtDNA content in female mouse germ cells
-
Cao, L., Shitara, H., Horii, T., Nagao, Y., Imai, H., Abe, K., Hara, T., Hayashi, J. and Yonekawa, H. (2007) The mitochondrial bottleneck occurs without reduction of mtDNA content in female mouse germ cells. Nat. Genet. 39, 386-390
-
(2007)
Nat. Genet
, vol.39
, pp. 386-390
-
-
Cao, L.1
Shitara, H.2
Horii, T.3
Nagao, Y.4
Imai, H.5
Abe, K.6
Hara, T.7
Hayashi, J.8
Yonekawa, H.9
-
31
-
-
38649091334
-
A reduction of mitochondrial DNA molecules during embryogenesis explains the rapid segregation of genotypes
-
Cree, L.M., Samuels, D.C., de Sousa Lopes, S.C., Rajasimha, H.K., Wonnapinij, P., Mann, J.R., Dahl, H.H. and Chinnery, P.F. (2008) A reduction of mitochondrial DNA molecules during embryogenesis explains the rapid segregation of genotypes. Nat. Genet. 40, 249-254
-
(2008)
Nat. Genet
, vol.40
, pp. 249-254
-
-
Cree, L.M.1
Samuels, D.C.2
De Sousa Lopes, S.C.3
Rajasimha, H.K.4
Wonnapinij, P.5
Mann, J.R.6
Dahl, H.H.7
Chinnery, P.F.8
-
32
-
-
56749180593
-
The mitochondrial DNA genetic bottleneck results from replication of a subpopulation of genomes
-
Wai, T., Teoli, D. and Shoubridge, E.A. (2008) The mitochondrial DNA genetic bottleneck results from replication of a subpopulation of genomes. Nat. Genet. 40, 1484-1488
-
(2008)
Nat. Genet
, vol.40
, pp. 1484-1488
-
-
Wai, T.1
Teoli, D.2
Shoubridge, E.A.3
-
33
-
-
17744393686
-
Mitochondrial DNA mutations in human disease
-
Taylor, R.W. and Turnbull, D.M. (2005) Mitochondrial DNA mutations in human disease. Nat. Rev. Genet. 6, 389-402
-
(2005)
Nat. Rev. Genet
, vol.6
, pp. 389-402
-
-
Taylor, R.W.1
Turnbull, D.M.2
-
34
-
-
33645124221
-
Analysis of mtDNA variant segregation during early human embryonic development: A tool for successful NARP preimplantation diagnosis
-
Steffann, J., Frydman, N., Gigarel, N., Burlet, P., Ray, P.F., Fanchin, R., Feyereisen, E., Kerbrat, V., Tachdjian, G., Bonnefont, J.P. et al. (2006) Analysis of mtDNA variant segregation during early human embryonic development: a tool for successful NARP preimplantation diagnosis. J. Med. Genet. 43, 244-247
-
(2006)
J. Med. Genet
, vol.43
, pp. 244-247
-
-
Steffann, J.1
Frydman, N.2
Gigarel, N.3
Burlet, P.4
Ray, P.F.5
Fanchin, R.6
Feyereisen, E.7
Kerbrat, V.8
Tachdjian, G.9
Bonnefont, J.P.10
-
35
-
-
28044448512
-
Gene therapy for progeny of mito-mice carrying pathogenic mtDNA by nuclear transplantation
-
Sato, A., Kono, T., Nakada, K., Ishikawa, K., Inoue, S., Yonekawa, H. and Hayashi, J. (2005) Gene therapy for progeny of mito-mice carrying pathogenic mtDNA by nuclear transplantation. Proc. Natl. Acad. Sci. U.S.A. 102, 16765-16770
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 16765-16770
-
-
Sato, A.1
Kono, T.2
Nakada, K.3
Ishikawa, K.4
Inoue, S.5
Yonekawa, H.6
Hayashi, J.7
-
36
-
-
70349284435
-
Mitochondrial gene replacement in primate offspring and embryonic stem cells
-
Tachibana, M., Sparman, M., Sritanaudomchai, H., Ma, H., Clepper, L., Woodward, J., Li, Y., Ramsey, C., Kolotushkina, O. and Mitalipov, S. (2009) Mitochondrial gene replacement in primate offspring and embryonic stem cells. Nature 461, 367-372
-
(2009)
Nature
, vol.461
, pp. 367-372
-
-
Tachibana, M.1
Sparman, M.2
Sritanaudomchai, H.3
Ma, H.4
Clepper, L.5
Woodward, J.6
Li, Y.7
Ramsey, C.8
Kolotushkina, O.9
Mitalipov, S.10
-
37
-
-
0027017232
-
Mitochondrial DNA deletions in human brain: Regional variability and increase with advanced age
-
Corral-Debrinski, M., Horton, T., Lott, M.T., Shoffner, J.M., Beal, M.F. and Wallace, D.C. (1992) Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age. Nat. Genet. 2, 324-329
-
(1992)
Nat. Genet
, vol.2
, pp. 324-329
-
-
Corral-Debrinski, M.1
Horton, T.2
Lott, M.T.3
Shoffner, J.M.4
Beal, M.F.5
Wallace, D.C.6
-
38
-
-
33646375711
-
High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease
-
Bender, A., Krishnan, K.J., Morris, C.M., Taylor, G.A., Reeve, A.K., Perry, R.H., Jaros, E., Hersheson, J.S., Betts, J., Klopstock, T. et al. (2006) High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease. Nat. Genet. 38, 515-517
-
(2006)
Nat. Genet
, vol.38
, pp. 515-517
-
-
Bender, A.1
Krishnan, K.J.2
Morris, C.M.3
Taylor, G.A.4
Reeve, A.K.5
Perry, R.H.6
Jaros, E.7
Hersheson, J.S.8
Betts, J.9
Klopstock, T.10
-
39
-
-
33646351299
-
Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons
-
Kraytsberg, Y., Kudryavtseva, E., McKee, A.C., Geula, C., Kowall, N.W. and Khrapko, K. (2006) Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons. Nat. Genet. 38, 518-520
-
(2006)
Nat. Genet
, vol.38
, pp. 518-520
-
-
Kraytsberg, Y.1
Kudryavtseva, E.2
McKee, A.C.3
Geula, C.4
Kowall, N.W.5
Khrapko, K.6
-
40
-
-
22344456832
-
Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging
-
Kujoth, G.C., Hiona, A., Pugh, T.D., Someya, S., Panzer, K., Wohlgemuth, S.E., Hofer, T., Seo, A.Y., Sullivan, R., Jobling, W.A. et al. (2005) Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging. Science 309, 481-484
-
(2005)
Science
, vol.309
, pp. 481-484
-
-
Kujoth, G.C.1
Hiona, A.2
Pugh, T.D.3
Someya, S.4
Panzer, K.5
Wohlgemuth, S.E.6
Hofer, T.7
Seo, A.Y.8
Sullivan, R.9
Jobling, W.A.10
-
41
-
-
2642580016
-
Premature ageing in mice expressing defective mitochondrial DNA polymerase
-
Trifunovic, A., Wredenberg, A., Falkenberg, M., Spelbrink, J.N., Rovio, A.T., Bruder, C.E., Bohlooly, Y.M., Gidlof, S., Oldfors, A., Wibom, R. et al. (2004) Premature ageing in mice expressing defective mitochondrial DNA polymerase. Nature 429, 417-423
-
(2004)
Nature
, vol.429
, pp. 417-423
-
-
Trifunovic, A.1
Wredenberg, A.2
Falkenberg, M.3
Spelbrink, J.N.4
Rovio, A.T.5
Bruder, C.E.6
Bohlooly, Y.M.7
Gidlof, S.8
Oldfors, A.9
Wibom, R.10
|