1,3,5-Trihydroxy-4-prenylxanthone represses lipopolysaccharide-induced iNOS expression via impeding posttranslational modification of IRAK-1

Biochemical Pharmacology

Volumn 81, Issue 6, 2011, Pages 752-760

  Chiou, Wen Fei ^a,b,c   Chen, Chien Chih ^c   Lin, I Hsin ^d   Chiu, Jen Hwey ^b   Chen, Yi Ju ^b  

^a NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c HUNGKUANG UNIVERSITY   (Taiwan)

^d NATIONAL TAIPEI UNIVERSITY OF NURSING AND HEALTH SCIENCES   (Taiwan)

Author keywords

1,3,5 Trihydroxy 4 prenylxanthone; Inducible nitric oxide synthase; Interleukin (IL) 1 receptor associated serine threonine kinase 1; Lipopolysaccharide; Transforming growth factor activated kinase 1

Indexed keywords

1,3,5 TRIHYDROXY 4 PRENYLXANTHONE; ANTIINFLAMMATORY AGENT; I KAPPA B; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; PROTEIN C FOS; PROTEIN C JUN; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR; TRANSCRIPTION FACTOR AP 1; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; UNCLASSIFIED DRUG; XANTHONE DERIVATIVE;

ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; ENZYME ACTIVATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UBIQUITINATION; WESTERN BLOTTING;

ANIMALS; CELL LINE; CELL SURVIVAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; LIPOPOLYSACCHARIDES; MICE; MORACEAE; NITRIC OXIDE SYNTHASE TYPE II; PLANT EXTRACTS; PLANT ROOTS; PROTEIN PROCESSING, POST-TRANSLATIONAL; XANTHONES;

EID: 79951959266     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2010.12.022     Document Type: Article

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