Transcriptomic effects of depleted uranium on acetylcholine and cholesterol metabolisms in Alzheimer's disease model

Comptes Rendus - Biologies

Volumn 334, Issue 2, 2011, Pages 85-90

  Lestaevel, Philippe ^a   Bensoussan, Hélène ^a   Racine, Radjini ^a   Airault, Fabrice ^a   Gourmelon, Patrick ^a   Souidi, Maâmar ^a  

^a INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE IRSN   (France)

Author keywords

Brain; Chronic exposure; Neurodegenerative disease; Toxicity

Indexed keywords

ABC TRANSPORTER A1; ACETYLCHOLINE; AMYLOID PRECURSOR PROTEIN; CHOLESTEROL; CHOLINE ACETYLTRANSFERASE; DRINKING WATER; MESSENGER RNA; URANIUM; VESICULAR ACETYLCHOLINE TRANSPORTER;

ALUMINUM; BRAIN; DRINKING WATER; ESTER; METABOLISM; NERVOUS SYSTEM DISORDER; PROTEIN; RODENT; TOXICITY; URANIUM;

ACETYLCHOLINE RELEASE; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; CHOLESTEROL METABOLISM; CONTROLLED STUDY; MALE; MOUSE; MOUSE STRAIN; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN FUNCTION; TG2576 MOUSE; TRANSCRIPTOMICS; TRANSGENIC MOUSE; WILD TYPE;

ACETYLCHOLINE; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CARRIER PROTEINS; CHOLESTEROL; DISEASE MODELS, ANIMAL; ENZYMES; FRONTAL LOBE; GENE EXPRESSION PROFILING; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MICE; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; POLYMERASE CHAIN REACTION; RECEPTORS, CHOLINERGIC; RNA, MESSENGER; URANYL NITRATE; WATER POLLUTANTS, CHEMICAL; WATER POLLUTANTS, RADIOACTIVE;

MUS; MUS MUSCULUS; RATTUS;

EID: 79951949882     PISSN: 16310691     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.crvi.2010.12.004     Document Type: Article

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