Non-covalent association of folate to lipoplexes: A promising strategy to improve gene delivery in the presence of serum

Journal of Controlled Release

Volumn 149, Issue 3, 2011, Pages 264-272

  Duarte, Sónia ^a   Faneca, Henrique ^a   Pedroso De Lima, Maria C ^a  

^a NONE

Author keywords

DNA protection; Folate associated lipoplexes; Gene delivery; Non covalent association; Serum resistance

Indexed keywords

BIOLOGICAL ACTIVITIES; CANCER CELL LINES; CATIONIC LIPOSOMES; CELL LINES; COVALENT COUPLINGS; DNA COMPLEX; ELECTROSTATIC ASSOCIATION; GENE DELIVERY; GENE DELIVERY SYSTEMS; IN-VITRO; IN-VIVO; INHIBITORY EFFECT; LIPOPLEXES; NON-COVALENT ASSOCIATION; NONVIRAL VECTORS; SERUM RESISTANCE; TARGET CELLS; THERAPEUTIC GENES; TRANSFECTION ACTIVITY; TRANSFECTION EFFICIENCY; VIRAL VECTORS;

BIOACTIVITY; BODY FLUIDS; CELL CULTURE; COMPLEXATION; DNA; GENE TRANSFER; LIPOSOMES; NUCLEIC ACIDS; PHOSPHOLIPIDS;

GENE THERAPY;

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; CHOLESTEROL; DEOXYRIBONUCLEASE I; DNA; FOLIC ACID; LIPOPLEX;

ANIMAL CELL; ARTICLE; BIOLOGICAL ACTIVITY; CANCER CELL; CELL VIABILITY; COMPLEX FORMATION; CONTROLLED STUDY; COVALENT BOND; CYTOTOXICITY TEST; FEMALE; GENE DELIVERY SYSTEM; GENE TARGETING; GENETIC TRANSFECTION; NONHUMAN; PRIORITY JOURNAL; SERUM; STATIC ELECTRICITY;

ANIMALS; CELL LINE, TUMOR; DNA; FOLIC ACID; GENE EXPRESSION; GENE THERAPY; GREEN FLUORESCENT PROTEINS; HUMANS; LIPOSOMES; MICE; NEOPLASMS; SERUM; STATIC ELECTRICITY; TRANSFECTION;

EID: 79951941675     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2010.10.032     Document Type: Article

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